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SUMMIT THERAPEUTICS INC. (SMMT)

(10% Negative) SUMMIT THERAPEUTICS INC. (SMMT) Announces Delay in endpoint Development Timeline Due to Geopolitical Situation, Pandemic-Related Challenges, Patient Enrollment Issues, Regulatory Process, Safety Review, Efficacy Assessment

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  • News bot Sept. 3, 2026, 1:22 p.m.

    📋 SUMMIT THERAPEUTICS INC. (SMMT) - Clinical Trial Update

    Filing Date: 2026-09-03

    Accepted: 2026-09-03 09:21:44

    Event Type: Clinical Trial Update

    Event Details:

    SUMMIT THERAPEUTICS INC. (SMMT) Announces Clinical Trial Update SUMMIT THERAPEUTICS INC. (SMMT) provided an update on its clinical development programs. Clinical Development Highlights:
    • Drug Program: endpoint, conducted
    • Clinical Stage: Phase III
    • Update Type: Trial Timeline Adjustment
    • Primary Factors: Geopolitical Situation, Pandemic-Related Challenges, Patient Enrollment, Regulatory Process
    • Collaboration: NMPA
    • Updated Timeline: April 2025

    🔬 Clinical Development Pipeline (SUMMIT THERAPEUTICS INC.):

    Product Type Development Stage Therapeutic Area Source
    Hyperbaric Oxygen Therapy (HBOT) Drug Phase PHASE2 Traumatic Brain Injury ClinicalTrials.gov
    Ligufalimab Other Phase PHASE3 Squamous Cell Carcinoma Head and Neck Cancer (HNSCC) ClinicalTrials.gov
    Drug: Bevacizumab Injection Drug Phase PHASE3 Metastatic Colorectal Cancer (CRC) ClinicalTrials.gov
    Change in SARS-CoV-2 Antibody Levels OTHER Preclinical Covid-19 ClinicalTrials.gov
    Drug: Ivonescimab Injection Drug Phase PHASE3 Metastatic Colorectal Cancer (CRC) ClinicalTrials.gov
    AK112 Other Phase PHASE2 Metastatic Colorectal Cancer ClinicalTrials.gov
    Leucovorin Other Phase PHASE2 Stomach Cancer Stage IV ClinicalTrials.gov
    Oxaliplatin Other Phase PHASE2 Stomach Cancer Stage IV ClinicalTrials.gov
    5-Fluorouracil Other Phase PHASE2 Stomach Cancer Stage IV ClinicalTrials.gov
    Ivonescimab Other Phase PHASE2 Stomach Cancer Stage IV ClinicalTrials.gov
    Ivonescimab 20 mg/kg Other Phase PHASE2 Extensive Stage Lung Small Cell Cancer ClinicalTrials.gov
    Ivonescimab 10 mg/kg Other Phase PHASE2 Extensive Stage Lung Small Cell Cancer ClinicalTrials.gov
    FOLFOX regimen Other Phase PHASE2 Biliary Tract Cancer ClinicalTrials.gov
    IP PTX Other Phase PHASE2 Phase II ClinicalTrials.gov
    Pembrolizumab Injection Other Phase PHASE3 Non-Small Cell Lung Cancer ClinicalTrials.gov
    Ivonescimab Injection Other Phase PHASE3 Non-Small Cell Lung Cancer ClinicalTrials.gov
    Docetaxel Other Phase PHASE2 TNBC ClinicalTrials.gov
    Carboplatin Other Phase PHASE2 TNBC ClinicalTrials.gov
    Placebo Injection Other Phase PHASE3 Non-Squamous Non-small Cell Lung Cancer ClinicalTrials.gov
    AK112 Injection Other Phase PHASE3 Non-Squamous Non-small Cell Lung Cancer ClinicalTrials.gov
    pemetrexed Other Phase PHASE2 Lung Cancer (NSCLC) ClinicalTrials.gov
    Questionnaire Administration Other Phase PHASE2 Thymus Carcinoma ClinicalTrials.gov
    Magnetic Resonance Imaging Other Phase PHASE2 Thymus Carcinoma ClinicalTrials.gov
    Computed Tomography Other Phase PHASE2 Thymus Carcinoma ClinicalTrials.gov
    Biospecimen Collection Other Phase PHASE2 Thymus Carcinoma ClinicalTrials.gov
    Biopsy Procedure Procedure Phase PHASE2 Thymus Carcinoma ClinicalTrials.gov
    Digital care Other Approved Pregnancy ClinicalTrials.gov
    Standard Care Other Approved Pregnancy ClinicalTrials.gov
    Blister pack Other Approved Pregnancy ClinicalTrials.gov
    Bottle pack Other Approved Pregnancy ClinicalTrials.gov
    Surgical Procedure Procedure Phase PHASE2 Advanced Head and Neck Squamous Cell Carcinoma ClinicalTrials.gov
    Positron Emission Tomography Other Phase PHASE2 Advanced Head and Neck Squamous Cell Carcinoma ClinicalTrials.gov
    Standard Learning Methodology Other Approved Workshop ClinicalTrials.gov
    Genomics & Science Dojo Learning Methodology Other Approved Workshop ClinicalTrials.gov
    Tepotinib Other Phase PHASE1 Non-Small Cell Lung Cancer ClinicalTrials.gov
    Stereotactic Radiosurgery (SRS) or Fractionated Stereotactic Radiotherapy (FSRT) Drug Phase PHASE2 Non Small Cell Lung Cancer ClinicalTrials.gov
    Paclitaxel-albumin Other Phase PHASE2 Non Small Cell Lung Cancer ClinicalTrials.gov
    Paclitaxel Other Phase PHASE2 Non Small Cell Lung Cancer ClinicalTrials.gov
    VENDY Other Phase PHASE4 Harm Reduction ClinicalTrials.gov
    Pembrolizumab (KEYTRUDA ®) Other Phase PHASE3 Squamous Cell Carcinoma Head and Neck Cancer (HNSCC) ClinicalTrials.gov
    FOLFIRI Protocol Other Phase PHASE2 Metastatic Colorectal Cancer ClinicalTrials.gov
    Bevacizumab Other Phase PHASE2 Metastatic Colorectal Cancer ClinicalTrials.gov
    Experimental: Adductor Canal perineural local anesthetic infusion Other Phase PHASE4 Postoperative Pain Following Knee Arthroplasty ClinicalTrials.gov
    Control: Femoral perineural local anesthetic infusion Other Phase PHASE4 Postoperative Pain Following Knee Arthroplasty ClinicalTrials.gov
    BLOOD PRESSURE MEASUREMENT Other Preclinical Peripheral Arterial Disease ClinicalTrials.gov
    BLOOD PRESSURE MEASURMENT Other Preclinical Peripheral Arterial Disease ClinicalTrials.gov
    Placebo Acupuncture Other Phase PHASE3 Fatigue ClinicalTrials.gov
    Acupuncture Other Phase PHASE3 Fatigue ClinicalTrials.gov
    SMT C1100 Other Phase PHASE1 Duchenne Muscular Dystrophy ClinicalTrials.gov
    Vancomycin Other Phase PHASE2 Clostridium Difficile Infection ClinicalTrials.gov
    SMT19969 Other Phase PHASE2 Clostridium Difficile Infection ClinicalTrials.gov
    Fidaxomicin Other Phase PHASE2 Clostridium Difficile Infection ClinicalTrials.gov
    Ridinilazole Other Phase PHASE2 Clostridium Difficile Infection ClinicalTrials.gov
    Replens and coconut oil Other Phase EARLY_PHASE1 Genitourinary Abnormality ClinicalTrials.gov
    Ezutromid Other Phase PHASE2 Duchenne Muscular Dystrophy ClinicalTrials.gov
    WAYA-Holiday Other Approved Cancer ClinicalTrials.gov
    WAYA-Wilderness Other Approved Cancer ClinicalTrials.gov
    STrategically Acquired Gradient Echo (STAGE) Other Approved MRI ClinicalTrials.gov
    Timolol Ophthalmic Solution 0.5 Percent Other Phase PHASE2 Open-Angle Glaucoma ClinicalTrials.gov
    Timolol Ophthalmic Suspension 0.5 Percent Other Phase PHASE2 Open-Angle Glaucoma ClinicalTrials.gov
    Nebivolol Ophthalmic Suspension 0.5 Percent Other Phase PHASE2 Open-Angle Glaucoma ClinicalTrials.gov
    Nebivolol Ophthalmic Suspension 1 Percent Other Phase PHASE2 Open-Angle Glaucoma ClinicalTrials.gov
    ketamine Other Phase EARLY_PHASE1 Multiple Sclerosis ClinicalTrials.gov
    Prescription for Action (SPHERES Model) Other Approved Pregnancy ClinicalTrials.gov
    Hyperbaric Oxygen Therapy Drug Phase PHASE2 TBI Traumatic Brain Injury ClinicalTrials.gov
    Irinotecan Other Phase PHASE2 Metastatic Colorectal Cancer ClinicalTrials.gov
    Capecitabine Other Phase PHASE2 Metastatic Colorectal Cancer ClinicalTrials.gov
    AK117 Other Phase PHASE2 Metastatic Colorectal Cancer ClinicalTrials.gov
    FLEXIBLE AND NAVIGATIONAL URETERAL ACCESS SHEATH (FANS) IN FLEXIBLE URETEROSCOPY (FURS) Other Preclinical Urolithiasis ClinicalTrials.gov
    CVAC® SYSTEM Other Preclinical Urolithiasis ClinicalTrials.gov
    Stereotactic Radiosurgery Procedure Phase PHASE1 Non-Small Cell Lung Cancer ClinicalTrials.gov
    Osimertinib Other Phase PHASE1 Non-Small Cell Lung Cancer ClinicalTrials.gov
    Dato-DXd Other Phase PHASE1 Non-Small Cell Lung Cancer ClinicalTrials.gov
    Daraxonrasib (Cohort B1 only) DRUG Phase PHASE1 Advanced Solid Tumors ClinicalTrials.gov
    Carboplatin/Cisplatin + Pemetrexed (Cohort B2 Only) DRUG Phase PHASE1 Advanced Solid Tumors ClinicalTrials.gov
    cetuximab (Cohort C2 Only) DRUG Phase PHASE1 Advanced Solid Tumors ClinicalTrials.gov
    Carboplatin/Cisplatin + Pemetrexed (Dose Expansion Only) DRUG Phase PHASE1 Advanced Solid Tumors ClinicalTrials.gov
    Zoldonrasib DRUG Phase PHASE1 Advanced Solid Tumors ClinicalTrials.gov
    Elironrasib DRUG Phase PHASE1 Advanced Solid Tumors ClinicalTrials.gov
    Daraxonrasib DRUG Phase PHASE1 Advanced Solid Tumors ClinicalTrials.gov
    perineural ropivacaine PROCEDURE Approved Amputation ClinicalTrials.gov

    💼 Business Developments:

    • Partnership
    • Acquisition
    • Licensing: Not available
    • Regulatory Approval
    • Executive Changes: Not available

    Structured Data:

    • Company Name: SUMMIT THERAPEUTICS INC.
    • Ticker Symbol: SMMT

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