ABBVIE INC. (ABBV) Announces Clinical Trial Update
ABBVIE INC. (ABBV) provided an update on its clinical development programs.
Clinical Development Highlights:
Collaboration: Apogee Therapeutics, Inc.
targeting multiple validated inflammatory pathways in large immunology and inflammation markets, including atopic dermatitis (AD), asthma, and chronic obstructive pulmonary disease (COPD). AbbVie Inc. +1 (847) 938-9190
targeting multiple validated inflammatory pathways. APG273 combines zumilokibart with APG333, an antibody that blocks thymic stromal lymphopoietin (TSLP), a signaling protein that acts as an early trigger of inflammation in the lungs. Phase 1 data showed that APG333 has a long half-life and was able to suppress relevant type 2 inflammatory markers for up to six months after dosing. The Phase 1 data with APG333 and positive interim results from a Phase 1b study of zumilokibart in asthma, support the potential of the APG273 combination with quarterly or twice-yearly injections in asthma. For additional background on the acquisition, please read the announcement press release here and view AbbVie's investor presentation here. Financial Terms AbbVie has acquired all outstanding Apogee common stock for $135.11 per share in cash, for a total equity value of approximately $10.9 billion. Apogee's common stock ceased trading on the NASDAQ stock exchange prior to market open on Sept. 3, 2026
targeting dermatologic, respiratory and other inflammatory and immunological diseases –Apogee's lead asset, zumilokibart, is a late-stage, half-life extended monoclonal antibody targeting IL-13, in development for patients with atopic dermatitis –Apogee's pipeline also includes APG273, a potential best-in-category long-acting combination targeting IL-13 and thymic stromal lymphopoietin (TSLP), in development for asthma –AbbVie reaffirms previously issued 2026
🔬 Clinical Development Pipeline (ABBVIE INC.):
Product
Type
Development Stage
Therapeutic Area
Source
XEN63 Glaucoma Treatment System
Drug
Phase PHASE3
Primary Open Angle Glaucoma
ClinicalTrials.gov
Placebo-Matching Atogepant
Other
Phase PHASE3
Episodic Migraine
ClinicalTrials.gov
Atogepant
Other
Phase PHASE3
Episodic Migraine
ClinicalTrials.gov
Placebo
Other
Phase PHASE2
Obesity
ClinicalTrials.gov
ABBV-295
Other
Phase PHASE2
Obesity
ClinicalTrials.gov
Placebo for Atogepant
Other
Phase PHASE3
Chronic Migraine
ClinicalTrials.gov
VOLITE XC
Other
Phase PHASE3
Neck Lines
ClinicalTrials.gov
Placebo for ABBV-142
Other
Phase PHASE2
Idiopathic Pulmonary Fibrosis
ClinicalTrials.gov
ABBV-142
Other
Phase PHASE2
Idiopathic Pulmonary Fibrosis
ClinicalTrials.gov
ABBV-701
Other
Phase PHASE2
Crohn's Disease
ClinicalTrials.gov
Trosunilimab
Other
Phase PHASE2
Crohn's Disease
ClinicalTrials.gov
Risankizumab
Other
Phase PHASE2
Crohn's Disease
ClinicalTrials.gov
Matching Placebo for PVEK
Other
Phase PHASE2
Acute Myeloid Leukemia
ClinicalTrials.gov
Azacitidine
Other
Phase PHASE2
Acute Myeloid Leukemia
ClinicalTrials.gov
Venetoclax
Other
Phase PHASE2
Acute Myeloid Leukemia
ClinicalTrials.gov
Pivekimab Sunirine
Other
Phase PHASE2
Acute Myeloid Leukemia
ClinicalTrials.gov
Artificial Tears
Other
Phase PHASE2
Diabetic Retinopathy
ClinicalTrials.gov
Topical Steroid
Other
Phase PHASE2
Diabetic Retinopathy
ClinicalTrials.gov
Sham
Other
Phase PHASE2
Diabetic Retinopathy
ClinicalTrials.gov
Surabgene Lomparvovec
Other
Phase PHASE2
Diabetic Retinopathy
ClinicalTrials.gov
Cisplatin
Other
Phase PHASE1
Non Small Cell Lung Carcinoma
ClinicalTrials.gov
Pemetrexed
Other
Phase PHASE1
Non Small Cell Lung Carcinoma
ClinicalTrials.gov
Carboplatin
Other
Phase PHASE1
Non Small Cell Lung Carcinoma
ClinicalTrials.gov
Pembrolizumab
Other
Phase PHASE1
Non Small Cell Lung Carcinoma
ClinicalTrials.gov
Budigalimab
Other
Phase PHASE1
Non Small Cell Lung Carcinoma
ClinicalTrials.gov
Telisotuzumab Adizutecan
Other
Phase PHASE1
Non Small Cell Lung Carcinoma
ClinicalTrials.gov
Nab-paclitaxel
Other
Phase PHASE1
Cancer
ClinicalTrials.gov
ABBV-181
Other
Phase PHASE1
Cancer
ClinicalTrials.gov
ABBV-368
Other
Phase PHASE1
Cancer
ClinicalTrials.gov
ABBV-927
Other
Phase PHASE1
Cancer
ClinicalTrials.gov
Panitumumab
Other
Phase PHASE2
Metastatic Colorectal Cancer
ClinicalTrials.gov
Bevacizumab
Other
Phase PHASE2
Metastatic Colorectal Cancer
ClinicalTrials.gov
Leucovorin
Other
Phase PHASE2
Metastatic Colorectal Cancer
ClinicalTrials.gov
Oxaliplatin
Other
Phase PHASE2
Metastatic Colorectal Cancer
ClinicalTrials.gov
Fluorouracil
Other
Phase PHASE2
Metastatic Colorectal Cancer
ClinicalTrials.gov
Telisotuzumab Vedotin
Other
Phase PHASE2
Non-Small Cell Lung Cancer
ClinicalTrials.gov
Lutikizumab
Other
Phase PHASE3
Hidradenitis Suppurativa
ClinicalTrials.gov
Amrubicin
Other
Phase PHASE3
Small Cell Lung Cancer
ClinicalTrials.gov
Lurbinectedin
Other
Phase PHASE3
Small Cell Lung Cancer
ClinicalTrials.gov
Topotecan
Other
Phase PHASE3
Small Cell Lung Cancer
ClinicalTrials.gov
ABBV-706
Other
Phase PHASE3
Small Cell Lung Cancer
ClinicalTrials.gov
Venetoclax Oral Tablet
Other
Phase PHASE1
Relapsed Adult AML
ClinicalTrials.gov
Etentamig
Other
Phase PHASE1
Multiple Myeloma
ClinicalTrials.gov
Pomalidomide
Other
Phase PHASE1
Multiple Myeloma
ClinicalTrials.gov
Dexamethasone
Other
Phase PHASE1
Multiple Myeloma
ClinicalTrials.gov
Daratumumab
Other
Phase PHASE1
Multiple Myeloma
ClinicalTrials.gov
Surzetoclax
Other
Phase PHASE1
Multiple Myeloma
ClinicalTrials.gov
Placebo-Matching Ubrogepant
Other
Phase PHASE3
Migraine
ClinicalTrials.gov
Ubrogepant
Other
Phase PHASE3
Migraine
ClinicalTrials.gov
Irinotecan
Other
Phase PHASE2
Metastatic Pancreatic Ductal Adenocarcinoma
ClinicalTrials.gov
Folinic acid/ Leucovorina
Other
Phase PHASE2
Metastatic Pancreatic Ductal Adenocarcinoma
ClinicalTrials.gov
Livmoniplimab
Other
Phase PHASE2
Non-Small Cell Lung Cancer
ClinicalTrials.gov
Adalimumab
Other
Phase PHASE3
Juvenile Psoriatic Arthritis
ClinicalTrials.gov
Mirvetuximab Soravtansine
Other
Phase PHASE2
Epithelial Ovarian Cancer
ClinicalTrials.gov
Bretisilocin
Other
Phase PHASE1
Healthy Volunteer
ClinicalTrials.gov
Breath Test
Other
Preclinical
IBD
ClinicalTrials.gov
VOLUX
Other
Phase PHASE4
Jawline and Neck Appearance
ClinicalTrials.gov
VOLUMA
Other
Phase PHASE4
Jawline and Neck Appearance
ClinicalTrials.gov
SKINVIVE
Other
Phase PHASE4
Jawline and Neck Appearance
ClinicalTrials.gov
OnabotulinumtoxinA
Other
Phase PHASE4
Jawline and Neck Appearance
ClinicalTrials.gov
Levonorgestrel/Ethinyl Estradiol
Other
Phase PHASE1
Healthy Volunteer
ClinicalTrials.gov
JUVÉDERM VOLIFT with Lidocaine
Other
Phase PHASE3
Nasolabial Folds
ClinicalTrials.gov
NOA LIFT
Other
Phase PHASE3
Nasolabial Folds
ClinicalTrials.gov
Zanubrutinib
Other
Phase PHASE2
Chronic Lymphocytic Leukemia
ClinicalTrials.gov
Magnetic Resonance Imaging
Other
Phase PHASE2
Chronic Lymphocytic Leukemia
ClinicalTrials.gov
Computed Tomography
Other
Phase PHASE2
Chronic Lymphocytic Leukemia
ClinicalTrials.gov
Bone Marrow Biopsy
Other
Phase PHASE2
Chronic Lymphocytic Leukemia
ClinicalTrials.gov
Bone Marrow Aspiration
Other
Phase PHASE2
Chronic Lymphocytic Leukemia
ClinicalTrials.gov
Biospecimen Collection
Other
Phase PHASE2
Chronic Lymphocytic Leukemia
ClinicalTrials.gov
Cyclophosphamide
Other
Phase PHASE3
Amyloid Light Chain (AL) Amyloidosis
ClinicalTrials.gov
Bortezomib
Other
Phase PHASE3
Amyloid Light Chain (AL) Amyloidosis
ClinicalTrials.gov
Itraconazole
Other
Phase PHASE1
Healthy Volunteers
ClinicalTrials.gov
ABBV-722
Other
Phase PHASE1
Healthy Volunteers
ClinicalTrials.gov
ABBV-319
Other
Phase PHASE1
Diffuse Large B-Cell Lymphoma
ClinicalTrials.gov
Ibrutinib
Other
Phase PHASE2
Mantle Cell Lymphoma (MCL)
ClinicalTrials.gov
standard of care chemotherapy plus gemtuzumab ozogamicin
📋 ABBVIE INC. (ABBV) - Clinical Trial Update
Filing Date: 2026-09-03
Accepted: 2026-09-03 08:47:46
Event Type: Clinical Trial Update
Event Details:
🔬 Clinical Development Pipeline (ABBVIE INC.):
💼 Business Developments:
Structured Data: