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  • News bot Jan. 9, 2026, 1:19 p.m.

    📋 APTEVO THERAPEUTICS INC. (APVO) - Clinical Trial Update

    Filing Date: 2026-01-09

    Accepted: 2026-01-09 08:17:21

    Event Type: Clinical Trial Update

    Event Details:

    Aptevo Therapeutics Inc. (APVO) Announces Clinical Trial Update Aptevo Therapeutics Inc. (APVO) provided an update on its clinical development programs. Clinical Development Highlights:
    • Collaboration: Company

    🔬 Clinical Development Pipeline (APTEVO THERAPEUTICS INC.):

    Product Type Development Stage Therapeutic Area Source
    ALG.APV-527 DRUG Phase PHASE1 Solid Tumor ClinicalTrials.gov
    Azacitidine DRUG Phase PHASE1 Acute Myeloid Leukemia (AML) ClinicalTrials.gov
    Venetoclax DRUG Phase PHASE1 Acute Myeloid Leukemia (AML) ClinicalTrials.gov
    Bevacizumab (Avastin) DRUG Phase PHASE1 Tumors ClinicalTrials.gov
    Combretastatin A4 Phosphate (CA4P) DRUG Phase PHASE1 Tumors ClinicalTrials.gov
    Combretastatin A-4 Phosphate DRUG Phase PHASE2 Choroidal Neovascularization ClinicalTrials.gov
    OXi4503 DRUG Phase PHASE1 Solid Tumors ClinicalTrials.gov
    Saline DRUG Phase PHASE2 Polypoidal Choroidal Vasculopathy ClinicalTrials.gov
    fosbretabulin DRUG Phase PHASE2 Polypoidal Choroidal Vasculopathy ClinicalTrials.gov
    Combretastatin A1 Diphosphate (OXi4503) DRUG Phase PHASE1 Neoplasm Metastasis ClinicalTrials.gov
    Combretastatin A-4 Phosphate + Paclitaxel + Carboplatin DRUG Phase PHASE2 Cancer ClinicalTrials.gov
    Placebo + paclitaxel + carboplatin DRUG Phase PHASE3 Anaplastic Thyroid Cancer ClinicalTrials.gov
    Fosbretabulin + paclitaxel + carboplatin DRUG Phase PHASE3 Anaplastic Thyroid Cancer ClinicalTrials.gov
    carboplatin DRUG Phase PHASE2 Anaplastic Thyroid Cancer ClinicalTrials.gov
    paclitaxel DRUG Phase PHASE2 Anaplastic Thyroid Cancer ClinicalTrials.gov
    CA4P DRUG Phase PHASE2 Anaplastic Thyroid Cancer ClinicalTrials.gov
    Bevacizumab DRUG Phase PHASE2 Tumors ClinicalTrials.gov
    TRU-016 (anti-CD37 protein therapeutic) DRUG Phase PHASE1 Chronic Lymphocytic Leukemia (CLL) ClinicalTrials.gov
    Rituximab DRUG Phase PHASE1 B-cell Small Lymphocytic Lymphoma Recurrent ClinicalTrials.gov
    Bendamustine DRUG Phase PHASE1 B-cell Small Lymphocytic Lymphoma Recurrent ClinicalTrials.gov
    TRU-016 DRUG Phase PHASE1 B-cell Small Lymphocytic Lymphoma Recurrent ClinicalTrials.gov
    ES414 BIOLOGICAL Phase PHASE1 Prostate Cancer ClinicalTrials.gov
    20 mg/kg TRU-016 and bendamustine DRUG Phase PHASE1 Chronic Lymphocytic Leukemia (CLL) ClinicalTrials.gov
    15 mg/kg TRU-016 and bendamustine DRUG Phase PHASE1 Chronic Lymphocytic Leukemia (CLL) ClinicalTrials.gov
    TRU-016 and bendamustine DRUG Phase PHASE1 Chronic Lymphocytic Leukemia (CLL) ClinicalTrials.gov
    TRU-016 10-20 mg/kg + bendamustine BIOLOGICAL Phase PHASE1 Chronic Lymphocytic Leukemia ClinicalTrials.gov
    TRU-016 10-20 mg/kg + ibrutinib BIOLOGICAL Phase PHASE1 Chronic Lymphocytic Leukemia ClinicalTrials.gov
    TRU-016 6-20 mg/kg + idelalisib + rituximab BIOLOGICAL Phase PHASE1 Chronic Lymphocytic Leukemia ClinicalTrials.gov
    TRU-016 20 mg/kg + Obinutuzumab BIOLOGICAL Phase PHASE1 Chronic Lymphocytic Leukemia ClinicalTrials.gov
    10 mg/kg TRU-016 + Rituximab BIOLOGICAL Phase PHASE1 Chronic Lymphocytic Leukemia ClinicalTrials.gov
    20 mg/kg TRU-016 + Rituximab BIOLOGICAL Phase PHASE1 Chronic Lymphocytic Leukemia ClinicalTrials.gov
    Dexamethasone DRUG Phase PHASE4 Covid19 ClinicalTrials.gov
    Placebo BIOLOGICAL Phase PHASE1 Psoriasis ClinicalTrials.gov
    APVO210 BIOLOGICAL Phase PHASE1 Psoriasis ClinicalTrials.gov
    APVO436 BIOLOGICAL Phase PHASE1 AML ClinicalTrials.gov

    💼 Business Developments:

    • Partnership
    • Acquisition: Not available
    • Licensing: Not available
    • Regulatory Approval
    • Executive Changes: Not available

    Structured Data:

    • Company Name: Aptevo Therapeutics Inc.
    • CIK: 0001671584
    • Ticker Symbol: APVO
    • Period End Date: 2026-01-08
    • Document Type: 8-K

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