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  • News bot Jan. 6, 2026, 12:17 p.m.

    📋 Aclaris Therapeutics, Inc. (ACRS) - Clinical Trial Update

    Filing Date: 2026-01-06

    Accepted: 2026-01-06 07:15:11

    Event Type: Clinical Trial Update

    Event Details:

    Aclaris Therapeutics Inc (ACRS) Announces Clinical Trial Update Aclaris Therapeutics Inc (ACRS) provided an update on its clinical development programs. Clinical Development Highlights:
    • Drug Program: Expected
    • Diseases/Conditions: immuno-inflammatory diseases
    • Collaboration: Phase 2b Trial
      • targeting IL-4Rα, it blocks both downstream IL-4 and IL-13, which are key cytokines involved in Th2-mediated inflammation and allergic diseases. ATI-052 exhibits potential best-in-class potency and utilizes the same TSLP antigen-binding fragment (Fab) region as bosakitug (ATI-045), retaining the dissociation kinetics, long residence time, and high potency advantages over comparator antibodies, but is engineered to bind more tightly to the neonatal Fc receptor (FcRn), potentially extending its half-life. ATI-052 has the potential to treat a variety of atopic, immunologic and respiratory diseases. Aclaris has the exclusive worldwide rights to ATI-052, excluding Greater China.​About Aclaris Therapeutics, Inc.Aclaris Therapeutics, Inc. is a clinical-stage biopharmaceutical company developing a pipeline of novel product candidates to address the needs of patients with immuno-inflammatory diseases who lack satisfactory treatment options. The company has a multi-stage portfolio of product candidates powered by a robust R&D engine. For additional information, please visit www.aclaristx.com and follow Aclaris on X (formerly Twitter) at @AclarisTx and on LinkedIn.​Cautionary Note Regarding Forward-Looking StatementsAny statements contained in this press release that do not describe historical facts may constitute forward-looking statements as that term is defined in the Private Securities Litigation Reform Act of 1995
      • Expected in First Quarter of 2026

    🔬 Clinical Development Pipeline (Aclaris Therapeutics, Inc.):

    Product Type Development Stage Therapeutic Area Source
    Placebo DRUG Phase PHASE2 Atopic Dermatitis ClinicalTrials.gov
    ATI-045 DRUG Phase PHASE2 Atopic Dermatitis ClinicalTrials.gov
    mFOLFIRINOX DRUG Phase PHASE1 Metastatic Pancreatic Ductal Adenocarcinoma ClinicalTrials.gov
    Zunsemetinib DRUG Phase PHASE1 Metastatic Pancreatic Ductal Adenocarcinoma ClinicalTrials.gov

    💼 Business Developments:

    • Partnership
    • Acquisition: Not available
    • Licensing: Not available
    • Regulatory Approval: Not available
    • Executive Changes: Not available

    Structured Data:

    • Company Name: Aclaris Therapeutics Inc
    • CIK: 0001557746
    • Ticker Symbol: ACRS
    • Period End Date: 2026-01-06
    • Document Type: 8-K