SymbolPYPD
NamePOLYPID LTD.
SectorHEALTH CARE
RegionMiddle East
IndustryBiotechnology: Pharmaceutical Preparations
Address18 HASIVIM STREET, PETACH TIKVA, 495376, Israel
Telephone+972 747195700
Fax
Email
Websitehttps://www.polypid.com
IncorporationUNDEFINED
Incorporated On
Employees
Fiscal Year
Public Since
ExchangesNASDAQ
Auditor
Audit StatusNOT PROVIDED
Reporting Status
CIK0001611842
Description

PolyPid Ltd is a clinical stage specialty pharmaceutical company engaged in research and development of products based on PLEX (Polymer-Lipid Encapsulation MatriX), the Companys proprietary drug delivery technology. PLEX is capable of encapsulating many types of drugs to enable targeted, localized drug delivery into the body over extended periods of time with pre-determined release rates thus optimizing drug treatment regimens. BonyPid, BonyPid-1000, BonyPid-500, PLEX, and D-PLEX are trademarks of the Company. The Company is subject to extensive regulation by the FDA, under the Federal Food, Drug, and Cosmetic Act, as well as by other federal, state, and local regulatory agencies.

Additional info from NASDAQ:
PolyPid Ltd is a clinical stage specialty pharmaceutical company engaged in research and development of products based on PLEX (Polymer-Lipid Encapsulation MatriX), the Companys proprietary drug delivery technology. PLEX is capable of encapsulating many types of drugs to enable targeted, localized drug delivery into the body over extended periods of time with pre-determined release rates thus optimizing drug treatment regimens. BonyPid, BonyPid-1000, BonyPid-500, PLEX, and D-PLEX are trademarks of the Company. The Company is subject to extensive regulation by the FDA, under the Federal Food, Drug, and Cosmetic Act, as well as by other federal, state, and local regulatory agencies.

2026-08-12 17:02

New Form S-8 - PolyPid Ltd. <b>Filed:</b> 2026-08-12 <b>AccNo:</b> 0001213900-26-088332 <b>Size:</b> 249 KB

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2026-08-12 15:00

New Form SCHEDULE 13G/A - PolyPid Ltd. <b>Filed:</b> 2026-08-12 <b>AccNo:</b> 0001622627-26-000017 <b>Size:</b> 15 KB

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2026-08-12 11:30

PolyPid Provides Corporate Update and Reports Second Quarter 2026 Financial Results

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2026-07-30 12:00

PolyPid to Report Second Quarter 2026 Financial Results and Operational Highlights on August 12, 2026

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2026-07-29 12:30

PolyPid Announces FDA Acceptance of NDA with Priority Review for D-PLEX₁₀₀

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2026-07-21 11:30

PolyPid Announces Exclusive Partnership with Azurity Pharmaceuticals for the Commercialization of D-PLEX₁₀₀ in the U.S. and Canada

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2026-07-17 20:05

Warshavsky Ori 🟢 acquired 46.0K shares (1 derivative) of PolyPid Ltd. (PYPD) at $4.46 Transaction Date: May 11, 2026 | Filing ID: 079167

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2026-07-17 20:04

Missulawin Jonathan 🟢 acquired 49.0K shares (1 derivative) of PolyPid Ltd. (PYPD) at $4.46 Transaction Date: May 11, 2026 | Filing ID: 079162

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2026-07-17 20:04

Hazan Dalit Fellous 🟢 acquired 75.0K shares (1 derivative) of PolyPid Ltd. (PYPD) at $4.46 Transaction Date: May 11, 2026 | Filing ID: 079161

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2026-07-17 20:03

Director Barenholz Yechezkel 🟢 acquired 9.1K shares (1 derivative) of PolyPid Ltd. (PYPD) at $4.46 Transaction Date: Jul 15, 2026 | Filing ID: 079159

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Trial ID Title Phase Indication Status Start Date Completion Date Source
NCT04411199 D-PLEX 312 - Safety and Efficacy of D-PLEX in the Prevention of Post Abdominal … Phase3 Surgical Site Infection Completed 2020-12-15 2025-05-10 ClinicalTrials.gov
NCT04233424 D-PLEX 311: Safety and Efficacy of D-PLEX in the Prevention of Post Abdominal S… Phase3 Surgical Site Infection Completed 2020-06-24 2022-09-02 ClinicalTrials.gov
NCT03558984 D-PLEX 302: Efficacy and Safety of D-PLEX in the Prevention of Sternal Infectio… Phase3 Surgical Site Infection Terminated 2019-12-17 2022-10-24 ClinicalTrials.gov
NCT03633123 D-PLEX 310: Safety and Efficacy of D-PLEX in the Prevention of Post Abdominal S… Phase2 Abdominal Surgery Completed 2018-10-04 2019-10-06 ClinicalTrials.gov
NCT02731573 Safety and Efficacy of D-PLEX in the Prevention of Sternal Infection Post Cardi… Phase1 Postoperative Wound Infection Superficial Incisional Completed 2016-10-12 2018-05-01 ClinicalTrials.gov
NCT02531100 BonyPid-500TM Bone Graft Substitute Study Na Peri Implantitis Completed 2016-03-01 2018-06-01 ClinicalTrials.gov
NCT02491047 Safety and Performance of BonyPid-1000™ in the Treatment of Gustilo I, II, IIIA… Na Tibial Fractures Completed 2015-10-01 2018-09-01 ClinicalTrials.gov
Total clinical trials: 7
Product Name Type Development Stage Therapeutic Area Study Status Trial ID
Standard of Care Other Phase PHASE3 Surgical Site Infection TERMINATED NCT03558984
D-PLEX Other Phase PHASE3 Surgical Site Infection TERMINATED NCT03558984
SOC treatment only Drug Approved Peri Implantitis COMPLETED NCT02531100
BonyPid 500TM implantation concomitantly to SOC treatment Drug Approved Peri Implantitis COMPLETED NCT02531100
Standard of Care (SOC) treatment Drug Approved Tibial Fractures COMPLETED NCT02491047
BonyPid-1000 Other Approved Tibial Fractures COMPLETED NCT02491047
Standard of Care Other Phase PHASE3 Surgical Site Infection TERMINATED NCT03558984
D-PLEX Other Phase PHASE3 Surgical Site Infection TERMINATED NCT03558984
Standard of Care (SoC) Other Phase PHASE3 Surgical Site Infection COMPLETED NCT04411199
D-PLEX Other Phase PHASE3 Surgical Site Infection COMPLETED NCT04411199
Open heart surgery Procedure Phase PHASE1 Postoperative Wound Infection Superficial Incisional COMPLETED NCT02731573
D-PLEX Other Phase PHASE1 Postoperative Wound Infection Superficial Incisional COMPLETED NCT02731573
Standard of Care (SoC) Other Phase PHASE2 Abdominal Surgery COMPLETED NCT03633123
D-PLEX Other Phase PHASE2 Abdominal Surgery COMPLETED NCT03633123
Standard of Care (SoC) Other Phase PHASE3 Surgical Site Infection COMPLETED NCT04233424
D-PLEX Other Phase PHASE3 Surgical Site Infection COMPLETED NCT04233424
Standard of Care (SoC) Other Phase PHASE3 Surgical Site Infection COMPLETED NCT04233424
D-PLEX Other Phase PHASE3 Surgical Site Infection COMPLETED NCT04233424
Standard of Care (SoC) Other Phase PHASE3 Surgical Site Infection COMPLETED NCT04233424
D-PLEX Other Phase PHASE3 Surgical Site Infection COMPLETED NCT04233424
Standard of Care (SoC) Other Phase PHASE3 Surgical Site Infection COMPLETED NCT04233424
D-PLEX Other Phase PHASE3 Surgical Site Infection COMPLETED NCT04233424
Standard of Care (SoC) Other Phase PHASE3 Surgical Site Infection COMPLETED NCT04233424
D-PLEX Other Phase PHASE3 Surgical Site Infection COMPLETED NCT04233424
Standard of Care (SoC) Other Phase PHASE3 Surgical Site Infection COMPLETED NCT04233424
D-PLEX Other Phase PHASE3 Surgical Site Infection COMPLETED NCT04233424
Standard of Care (SoC) Other Phase PHASE3 Surgical Site Infection COMPLETED NCT04233424
D-PLEX Other Phase PHASE3 Surgical Site Infection COMPLETED NCT04233424
Standard of Care (SoC) Other Phase PHASE3 Surgical Site Infection COMPLETED NCT04233424
D-PLEX Other Phase PHASE3 Surgical Site Infection COMPLETED NCT04233424
Standard of Care (SoC) Other Phase PHASE3 Surgical Site Infection COMPLETED NCT04233424
D-PLEX Other Phase PHASE3 Surgical Site Infection COMPLETED NCT04233424
Standard of Care (SoC) OTHER Phase PHASE3 Surgical Site Infection COMPLETED NCT04411199
Standard of Care OTHER Phase PHASE3 Surgical Site Infection TERMINATED NCT03558984
Open heart surgery PROCEDURE Phase PHASE1 Postoperative Wound Infection Superficial Incisional COMPLETED NCT02731573
D-PLEX DRUG Phase PHASE3 Surgical Site Infection COMPLETED NCT04411199
SOC treatment only OTHER Approved Peri Implantitis COMPLETED NCT02531100
BonyPid 500TM implantation concomitantly to SOC treatment DEVICE Approved Peri Implantitis COMPLETED NCT02531100
Standard of Care (SOC) treatment OTHER Approved Tibial Fractures COMPLETED NCT02491047
BonyPid-1000 DEVICE Approved Tibial Fractures COMPLETED NCT02491047
Total products: 40