| Symbol | PCRX |
|---|---|
| Name | PACIRA BIOSCIENCES, INC. |
| Sector | HEALTH CARE |
| Region | North America |
| Industry | Biotechnology: Pharmaceutical Preparations |
| Address | 5401 WEST KENNEDY BOULEVARD,SUITE 890, TAMPA, Florida, 33609, United States |
| Telephone | +1 813 553-6680 |
| Fax | — |
| — | |
| Website | https://www.pacira.com |
| Incorporation | UNDEFINED |
| Incorporated On | — |
| Employees | — |
| Fiscal Year | — |
| Public Since | — |
| Exchanges | NASDAQ |
| Auditor | — |
| Audit Status | NOT PROVIDED |
| Reporting Status | — |
| CIK | 0001396814 |
| Description | Pacira BioSciences Inc is a provider of non-opioid pain management and regenerative health solutions dedicated to advancing and improving outcomes for health care practitioners and their patients. The company has launched EXPAREL which utilizes DepoFoam, a product delivery technology that encapsulates drugs without altering their molecular structure, and releases them over a desired period of time. Additional info from NASDAQ: |
SLONIN JONATHAN 🔴 sold 3.0K shares of Pacira BioSciences, Inc. (PCRX) at $23.23 Transaction Date: Aug 17, 2026 | Filing ID: 057759
Read more📋 SLONIN JONATHAN (Officer) plans to sell 3K shares of Pacira BioSciences, Inc. (at $23.23 each, total $71K) Filed: Aug 17, 2026 | ID: 006073
Read morePacira BioSciences Reports Inducement Grants Under Nasdaq Listing Rule 5635(c)(4)
Read moreNew Form SCHEDULE 13G - Pacira BioSciences, Inc. <b>Filed:</b> 2026-08-07 <b>AccNo:</b> 0000093751-26-000517 <b>Size:</b> 8 KB
Read morePacira BioSciences Announces Publication of Positive Two-Year Phase 1 Data For PCRX-201 in Annals of the Rheumatic Diseases
Read morePacira BioSciences Announces New National Survey Revealing the Hidden Toll of Pain on America’s Workforce
Read morePacira to Report Second Quarter 2026 Financial Results on Tuesday August 4, 2026
Read morePacira BioSciences Reports Inducement Grants Under Nasdaq Listing Rule 5635(c)(4)
Read more| Trial ID | Title | Phase | Indication | Status | Start Date | Completion Date | Source |
|---|---|---|---|---|---|---|---|
| NCT07584915 | Pilot Study on EXPAREL as an Intra-articular Posteromedial Surgeon Administered… | Phase4 | Total Knee Arthroplasty | Enrolling_By_Invitation | 2026-06-01 | 2026-08-01 | ClinicalTrials.gov |
| NCT07214844 | A Prospective Study to Evaluate the Efficacy of Iovera Lumbar Medial Branch Cry… | Na | Low Back Pain, Chronic | Recruiting | 2026-04-16 | 2028-05-01 | ClinicalTrials.gov |
| NCT07212114 | Efficacy of EXPAREL vs. Bupivacaine | Phase3 | Total Ankle Arthroplasty | Recruiting | 2025-11-17 | 2029-08-01 | ClinicalTrials.gov |
| NCT06946368 | Effectiveness of Exparel Anesthetic Administered by the Surgeon During Knee Sur… | Na | Total Knee Arthroplasty | Recruiting | 2025-08-18 | 2026-12-11 | ClinicalTrials.gov |
| NCT06958289 | Cryoneurolysis for Spasticity Treatment: Long-term Clinical Outcomes and Mechan… | Na | Spasticity as Sequela of Stroke | Recruiting | 2025-08-01 | 2028-05-01 | ClinicalTrials.gov |
| NCT07125833 | Cryoneurolysis of the Suprascapular Nerve for Perioperative Pain Control After … | Na | Degenerative Joint Disease of Shoulder | Recruiting | 2025-07-30 | 2026-08-01 | ClinicalTrials.gov |
| NCT06977568 | A Study to Evaluate an Intra-Articular Injection of ZILRETTA Versus Triamcinolo… | Phase2 | Osteoarthritis of Hip | Terminated | 2025-07-25 | 2025-10-16 | ClinicalTrials.gov |
| NCT06995352 | Liposomal Bupivacaine Versus Continuous Peripheral Nerve Blocks for Analgesia F… | Phase4 | Moderate-to-severely Painful Ankle Surgery | Enrolling_By_Invitation | 2025-06-23 | 2027-06-22 | ClinicalTrials.gov |
| NCT06935539 | Cryoneurolysis vs Radiofrequency Ablation for Chronic Sacroiliac Joint Pain | Na | Chronic Sacroiliac Joint Pain | Not_Yet_Recruiting | 2025-05-01 | 2026-08-01 | ClinicalTrials.gov |
| NCT06884865 | A Study to Assess Safety and Tolerability of PCRX-201 in Subjects With Painful … | Phase2 | Osteoarthritis (OA) of the Knee | Recruiting | 2025-02-26 | 2032-07-01 | ClinicalTrials.gov |
| NCT06603051 | The Effect of Pre-Operative Cryoneurolysis on Post-Operative Narcotic Consumpti… | Na | ACL Repair | Recruiting | 2024-08-28 | 2027-10-01 | ClinicalTrials.gov |
| NCT06340451 | Study to Assess the Efficacy and Safety of Iovera®° System in Subjects With Upp… | Na | Spasticity, Cerebral or Spinal Condition | Active_Not_Recruiting | 2024-07-11 | 2026-10-01 | ClinicalTrials.gov |
| NCT06284109 | Preoperative (Pre-amputation) Cryoanalgesia to Improve Post-amputation Phantom … | Na | Postoperative Pain | Withdrawn | 2024-06-01 | 2024-09-10 | ClinicalTrials.gov |
| NCT06350981 | Analgesic Requirement for Post-Operative Pain Control in TLIP Interbody Fusion | Phase2 | Back Pain | Enrolling_By_Invitation | 2024-04-30 | 2026-03-01 | ClinicalTrials.gov |
| NCT06340932 | Impact of Opioid Avoidance Protocol for ACL Reconstruction | — | ACL Tear | Completed | 2024-04-27 | 2025-02-01 | ClinicalTrials.gov |
| NCT06271265 | Study to Evaluate the Pharmacokinetics and Safety of EXPAREL for Postoperative … | Phase1 | Postoperative Pain | Recruiting | 2024-03-29 | 2027-01-01 | ClinicalTrials.gov |
| NCT06269705 | ZILRETTA in Subjects With Shoulder Osteoarthritis | Phase3 | Glenohumeral Osteoarthritis | Active_Not_Recruiting | 2024-02-05 | 2026-12-01 | ClinicalTrials.gov |
| NCT06077422 | Exparel vs. Marcaine ESP Block for Post-cardiac Surgical Pain | Phase2 | Pain, Postoperative | Enrolling_By_Invitation | 2024-01-11 | 2027-04-05 | ClinicalTrials.gov |
| NCT06093776 | Rib Fracture Cryoanalgesia | — | Pain Management Improvement | Completed | 2023-06-05 | 2025-06-12 | ClinicalTrials.gov |
| NCT05456490 | Phase 1, Dose Escalation Study to Evaluate of Safety, Pharmacokinetics and Phar… | Phase1 | Healthy | Completed | 2023-04-18 | 2025-02-27 | ClinicalTrials.gov |
| NCT05730920 | IV Methadone Vs EXPAREL Erector Spinae Plane Blockade in Pediatric Subjects Und… | Phase4 | Adolescent Idiopathic Scoliosis | Completed | 2022-10-19 | 2024-09-21 | ClinicalTrials.gov |
| NCT05604144 | Cryoanalgesia for the Treatment of Pain in Subjects With Morton's Neuroma | Na | Morton's Neuroma | Unknown | 2022-08-22 | 2023-04-22 | ClinicalTrials.gov |
| NCT06016127 | Cryoneurolysis for Facet Mediated Chronic Low Back Pain | Na | Low Back Pain | Completed | 2022-06-18 | 2023-10-23 | ClinicalTrials.gov |
| NCT05157841 | Phase 3, Sciatic Nerve Block With EXPAREL for Subjects Undergoing Bunionectomy | Phase3 | Bunionectomy | Completed | 2022-02-15 | 2022-08-17 | ClinicalTrials.gov |
| NCT05139030 | Phase 3 Adductor Canal Block With EXPAREL in Subjects Undergoing Primary Unilat… | Phase3 | Knee Osteoarthritis | Completed | 2022-01-18 | 2022-07-11 | ClinicalTrials.gov |
| NCT05495334 | Innovations in Genicular Outcomes Registry | — | Knee Osteoarthritis | Recruiting | 2021-09-23 | 2033-12-30 | ClinicalTrials.gov |
| NCT04117074 | Thoracic Epidural Analgesia vs Surgical Site Infiltration With Liposomal Bupiva… | Phase3 | Surgery | Completed | 2021-04-14 | 2025-03-17 | ClinicalTrials.gov |
| NCT04826328 | Study to Evaluate the Safety and Tolerability of FX301 in Patients Undergoing B… | Phase1 | Pain, Postoperative | Completed | 2021-03-15 | 2022-03-30 | ClinicalTrials.gov |
| NCT04504812 | A Sequenced Strategy for Improving Outcomes in People With Knee Osteoarthritis … | Phase3 | Knee Osteoarthritis | Completed | 2021-02-01 | 2025-04-08 | ClinicalTrials.gov |
| NCT04518462 | Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of EXPAREL, EXPARE… | Phase3 | Lower Extremity Surgery | Completed | 2020-10-20 | 2021-04-05 | ClinicalTrials.gov |
| NCT04191031 | Study to Evaluate Iovera®° in Adult Patients Undergoing Total Knee Arthroplasty | Na | Post-Operative Pain Management | Terminated | 2020-09-30 | 2022-07-12 | ClinicalTrials.gov |
| NCT04182672 | Study to Assess the Safety and Efficacy of FX006 Administered to Patients With … | Phase2 | Trochanteric Bursitis | Completed | 2020-08-12 | 2022-12-14 | ClinicalTrials.gov |
| NCT04261049 | Effect of Zilretta Injection | Phase1 | Osteoarthritis, Knee | Completed | 2020-08-01 | 2022-01-10 | ClinicalTrials.gov |
| NCT03954639 | Phase 3, Randomized, Double Blinded, Active Controlled, Multicenter Study to Ev… | Phase3 | Bunion | Withdrawn | 2020-06-15 | 2020-09-01 | ClinicalTrials.gov |
| NCT04173611 | Evaluation of Safety, Pharmacokinetics and Pharmacodynamics of EXPAREL® Adminis… | Phase1 | Healthy | Terminated | 2020-06-08 | 2020-12-07 | ClinicalTrials.gov |
| NCT04119687 | Study to Evaluate the Safety and Tolerability of FX201 in Patients with Osteoar… | Phase1 | Osteoarthritis, Knee | Active_Not_Recruiting | 2020-03-02 | 2026-11-28 | ClinicalTrials.gov |
| NCT04293809 | Study to Evaluate the Pharmacokinetics and Safety of EXPAREL Administered as a … | Phase1 | Breast Augmentation | Completed | 2019-12-19 | 2020-01-29 | ClinicalTrials.gov |
| NCT03738696 | Liposomal Bupivacaine in Rotator Cuff Repair | Phase4 | Rotator Cuff Injury | Completed | 2019-12-15 | 2022-01-01 | ClinicalTrials.gov |
| NCT04160091 | Study to Evaluate the Efficacy and Safety of FX006 in Patients With Glenohumera… | Phase2 | Osteoarthritis of the Shoulder | Terminated | 2019-11-07 | 2020-06-15 | ClinicalTrials.gov |
| NCT03739021 | Exparel for Total Shoulder Pain | Phase2 | Chronic Shoulder Pain | Not_Yet_Recruiting | 2019-11-01 | 2020-11-15 | ClinicalTrials.gov |
| NCT03827291 | QL Block With Exparel in Colectomy | Phase4 | Laparotomy | Completed | 2019-10-31 | 2022-12-09 | ClinicalTrials.gov |
| NCT03907033 | Liposomal Bupivacaine in Vaginal Hysterectomy | Phase4 | Vaginal Hysterectomy | Terminated | 2019-09-03 | 2021-07-23 | ClinicalTrials.gov |
| NCT03955458 | EXPAREL Facia Iliaca Compartment Block for Intertrochanteric Hip Fracture | Phase4 | Hip Fractures | Withdrawn | 2019-08-26 | 2020-05-01 | ClinicalTrials.gov |
| NCT03975283 | Use of Exparel for Postoperative Analgesia Following Bariatric Surgery | Phase4 | Post Operative Pain | Unknown | 2019-08-01 | 2021-08-01 | ClinicalTrials.gov |
| NCT03927911 | Phase 4 Study in Adult Subjects Undergoing Posterior Lumbar Spine Surgeries | Phase4 | Postoperative Pain Management | Terminated | 2019-07-31 | 2020-08-04 | ClinicalTrials.gov |
| NCT04065074 | Study to Evaluate a Procedure for Intra-articular Injection of FX006 in Patient… | Phase2 | Osteoarthritis, Hip | Completed | 2019-07-30 | 2019-12-30 | ClinicalTrials.gov |
| NCT04002089 | Study to Evaluate the Pharmacokinetics, Pharmacodynamics and Safety, of EXPAREL… | Phase1 | Bunion | Completed | 2019-07-26 | 2019-12-02 | ClinicalTrials.gov |
| NCT03909516 | Evaluate the Iovera° Device in Treating Pain Associated With Anterior Cruciate … | Na | ACL Reconstruction | Withdrawn | 2019-05-01 | 2019-05-01 | ClinicalTrials.gov |
| NCT03682302 | Multicenter Study for Pediatric Subjects Evaluating Pharmacokinetics and Safety… | Phase3 | Postoperative Pain Management | Completed | 2019-04-02 | 2019-09-24 | ClinicalTrials.gov |
| NCT03853694 | Efficacy and Safety of EXPAREL Versus Standard of Care (SoC) in Subjects Underg… | Phase4 | Elective Cesarean Section | Completed | 2019-03-04 | 2020-01-16 | ClinicalTrials.gov |
| NCT03836313 | Assessing if Cryoneurolysis Improves Prehabilitation and Decreases Pain After S… | Na | Arthropathy of Knee | Withdrawn | 2019-03-01 | 2021-06-01 | ClinicalTrials.gov |
| NCT03802864 | Post-operative Pain Control of Testicular Sperm Extraction Using Liposomal Bupi… | Phase4 | Male Infertility | Completed | 2019-02-04 | 2020-01-30 | ClinicalTrials.gov |
| NCT03793010 | Study to Evaluate the Efficacy and Safety of FX006 in Patients With Hip Osteoar… | Phase3 | Osteoarthritis, Hip | Terminated | 2018-12-12 | 2019-08-07 | ClinicalTrials.gov |
| NCT03270514 | Comparison of Sternal Wound Infiltration With Liposomal Bupivacaine v. Bupivaca… | Phase3 | Coronary Artery Disease | Completed | 2018-11-15 | 2020-02-25 | ClinicalTrials.gov |
| NCT03688477 | Iovera° to Treat Pain Associated With ACL Reconstruction and Rehabilitation | Na | Anterior Cruciate Ligament Reconstruction | Withdrawn | 2018-10-01 | 2019-06-01 | ClinicalTrials.gov |
| NCT03578237 | Cryoanalgesia to Prevent Acute and Chronic Pain Following Surgery: A Randomized… | Na | Mastectomy | Completed | 2018-08-25 | 2022-11-25 | ClinicalTrials.gov |
| NCT03541941 | Exparel vs. Bupivacaine Hydrochloride vs. Placebo for Hernia Repair | Phase4 | Analgesia, Postoperative | Completed | 2018-07-03 | 2019-12-19 | ClinicalTrials.gov |
| NCT03428984 | Study in Adult Subjects Undergoing Posterolateral Thoracotomy | Phase1 | Postoperative Pain Management | Terminated | 2018-05-03 | 2018-09-28 | ClinicalTrials.gov |
| NCT03529942 | Study to Evaluate the Effect of FX006 on Synovial Inflammation in Patients With… | Phase3 | Osteoarthritis, Knee | Completed | 2018-04-24 | 2020-03-09 | ClinicalTrials.gov |
| NCT03485014 | Study in Pediatric Subjects Evaluating Pharmacokinetics and Safety of EXPAREL | Phase1 | Postoperative Pain Management | Completed | 2018-04-10 | 2019-02-12 | ClinicalTrials.gov |
| NCT03382262 | Study to Compare Exposure of TA Following Administration of FX006 or TAcs in Pa… | Phase2 | Osteoarthritis of the Shoulder | Completed | 2017-12-18 | 2018-10-09 | ClinicalTrials.gov |
| NCT03378076 | Study to Compare Exposure of TA Following Administration of Either FX006 or TAc… | Phase2 | Bilateral Knee Osteoarthritis | Completed | 2017-12-06 | 2018-03-14 | ClinicalTrials.gov |
| NCT03149887 | Liposomal Bupivacaine After Arthroscopic Rotator Cuff Repair | Phase4 | Rotator Cuff Tear | Completed | 2017-12-05 | 2019-03-01 | ClinicalTrials.gov |
| NCT03327220 | Treatment With Iovera° for Total Knee Arthroplasty (TKA) Post-Operative Pain | Na | Total Knee Arthroplasty | Completed | 2017-11-06 | 2019-03-27 | ClinicalTrials.gov |
| NCT03076710 | Post-Operative Pain Management Following Spine Surgery | — | Pain Management | Withdrawn | 2017-07-31 | 2022-03-01 | ClinicalTrials.gov |
| NCT03176459 | Evaluate the Safety and Efficacy of EXPAREL When Administered Via Infiltration … | Phase4 | C-Section | Completed | 2017-06-01 | 2018-12-04 | ClinicalTrials.gov |
| NCT03015961 | Phase 4, Controlled Study in Adult Subjects Undergoing Primary, 1-2 Level, Open… | Phase4 | Postoperative Pain Management | Terminated | 2017-02-21 | 2017-10-30 | ClinicalTrials.gov |
| NCT03046446 | Study to Assess the Safety of Repeat Administration of FX006 Administered to Pa… | Phase3 | Osteoarthritis of the Knee | Completed | 2017-02-20 | 2018-07-19 | ClinicalTrials.gov |
| NCT03106519 | Liposome Bupivacaine for WRIST Blocks | Phase2 | Dupuytren's Contracture of the Hand (Viking's Disease) | Completed | 2017-01-02 | 2017-10-31 | ClinicalTrials.gov |
| NCT03106545 | Liposome Bupivacaine for ANKLE Blocks | Phase2 | Hallux Valgus (Bunions) | Completed | 2017-01-02 | 2017-10-31 | ClinicalTrials.gov |
| NCT02985762 | PK Study of EXPAREL in Subjects Undergoing Open Spinal Fusion or Reconstructive… | Phase1 | Spinal Fusion | Completed | 2016-12-01 | 2017-09-01 | ClinicalTrials.gov |
| NCT02922582 | Study of Local Administration of DepoTXA for Reduced Postsurgical Bleeding in S… | Phase2 | Total Knee Arthroplasty | Terminated | 2016-10-28 | 2017-11-27 | ClinicalTrials.gov |
| NCT02821325 | Intra-articular Volumetric Assessment After Total Knee Arthroplasty | — | Hematoma | Completed | 2016-09-28 | 2018-01-30 | ClinicalTrials.gov |
| NCT02740114 | Wound Infiltration With Liposomal Bupivacaine vs. Standard Wound Infiltration W… | Phase3 | Malignant Neoplasms of Female Genital Organs | Terminated | 2016-08-31 | 2020-07-23 | ClinicalTrials.gov |
| NCT02713178 | Efficacy, Safety, and Pharmacokinetics of Femoral Nerve Block With EXPAREL in T… | Phase3 | Pain | Completed | 2016-06-03 | 2017-06-30 | ClinicalTrials.gov |
| NCT02713230 | Efficacy, Safety, and Pharmacokinetics of Brachial Plexus Block With EXPAREL in… | Phase3 | Pain | Completed | 2016-05-09 | 2017-07-07 | ClinicalTrials.gov |
| NCT02713490 | Local Infiltration Analgesia With and Without EXPAREL Following Total Knee Arth… | Phase4 | Pain | Completed | 2016-04-18 | 2017-02-08 | ClinicalTrials.gov |
| NCT02762370 | Study to Assess the Effects of FX006 on Blood Glucose in Patients With OA of th… | Phase2 | Osteoarthritis of the Knee | Completed | 2016-04-01 | 2016-11-01 | ClinicalTrials.gov |
| NCT02637323 | Study to Characterize the PK and Local Extent and Duration of Exposure From FX0… | Phase2 | Osteoarthritis of the Knee | Completed | 2015-11-01 | 2016-09-01 | ClinicalTrials.gov |
| NCT03290196 | The Effect of EXPAREL® on Postsurgical Pain, and the Use of Narcotics | Phase4 | Rotator Cuff Tear | Terminated | 2015-09-03 | 2022-04-07 | ClinicalTrials.gov |
| NCT02517905 | Evaluation of EXPAREL for Prolonged Postsurgical Analgesia in Subjects Undergoi… | Phase3 | Dental Pain | Completed | 2015-08-01 | 2016-01-01 | ClinicalTrials.gov |
| NCT02554357 | Quality of Analgesia After Interscalene Block After Arthroscopic Shoulder Surge… | Na | Injury of Shoulder Region | Completed | 2015-07-01 | 2016-03-01 | ClinicalTrials.gov |
| NCT02353754 | Evaluation of the Safety and Efficacy of EXPAREL When Administered Into the TAP… | Phase4 | Pain | Terminated | 2015-05-01 | 2015-07-01 | ClinicalTrials.gov |
| NCT02468583 | Proof of Concept Study Comparing FX006 to Kenalog®-40 in Patients With Post-Tra… | Phase2 | Post-traumatic Osteoarthritis of the Knee | Terminated | 2015-02-01 | 2016-07-01 | ClinicalTrials.gov |
| NCT02357459 | Study of FX006 for the Treatment of Pain in Patients With Osteoarthritis of the… | Phase3 | Osteoarthritis of the Knee | Completed | 2015-01-01 | 2016-01-01 | ClinicalTrials.gov |
| NCT02284386 | Pharmacokinetics and Safety of Bupivacaine HCl Spinal Block and EXPAREL Local I… | Phase4 | Pain | Completed | 2014-12-01 | 2015-03-01 | ClinicalTrials.gov |
| NCT02284113 | A Randomized, Study to Evaluate the Iovera° Device in Treating Pain Associated … | Na | Arthritis of the Knee | Completed | 2014-12-01 | 2016-06-01 | ClinicalTrials.gov |
| NCT02260921 | Study to Evaluate the Iovera° Device for Temporary Relief From Knee Pain | Na | Knee Osteoarthritis | Completed | 2014-10-20 | 2016-05-31 | ClinicalTrials.gov |
| NCT02255500 | EXPAREL Infiltration in Subjects Undergoing Femoral Nerve Block With Bupivacain… | Phase4 | Pain | Completed | 2014-09-01 | 2015-03-01 | ClinicalTrials.gov |
| NCT04278846 | Efficacy of Liposomal Bupivacaine for Prolonged Postoperative Analgesia in Pati… | Phase4 | Pain, Postoperative | Completed | 2014-08-22 | 2019-05-15 | ClinicalTrials.gov |
| NCT02787226 | Liposomal Bupivacaine Infiltration vs Continuous Perineural Ropivacaine Infusio… | Phase4 | Postoperative Pain | Terminated | 2014-08-01 | 2017-05-31 | ClinicalTrials.gov |
| NCT02210247 | Safety and Pharmacokinetics Study of Redosing EXPAREL in Healthy Volunteers | Phase1 | Healthy Volunteers | Completed | 2014-08-01 | 2014-09-01 | ClinicalTrials.gov |
| NCT02199574 | Pharmacokinetic Evaluation of EXPAREL in Adults Undergoing Tonsillectomy | Phase4 | Pain | Completed | 2014-08-01 | 2015-06-01 | ClinicalTrials.gov |
| NCT02116972 | Study of FX006 vs Normal Saline in Patients With Osteoarthritis of the Knee | Phase2 | Osteoarthritis of the Knee | Completed | 2014-04-01 | 2015-11-01 | ClinicalTrials.gov |
| NCT02128646 | Liposomal Bupivacaine (Exparel) for Postoperative Pain Control for Open and Lap… | Phase4 | Pain | Completed | 2014-04-01 | 2017-01-01 | ClinicalTrials.gov |
| NCT02586077 | Foot and Ankle Clinic Application for Liposomal Related Anesthetic | Phase4 | Ankle Arthrodesis | Completed | 2014-02-01 | 2016-11-15 | ClinicalTrials.gov |
| NCT02058303 | Study of A Long Lasting Local Anesthestic for Hand, Wrist or Finger Surgery | Phase4 | Hand Injuries | Terminated | 2014-02-01 | 2016-03-01 | ClinicalTrials.gov |
| NCT02003365 | Study to Characterize the Local Duration of Exposure From FX006 in Patients Wit… | Phase2 | Osteoarthritis of the Knee | Completed | 2013-11-01 | 2014-04-01 | ClinicalTrials.gov |
| NCT01950065 | Effectiveness and Safety Study of the Iovera Device for the Temporary Reduction… | Na | Forehead Wrinkles | Completed | 2013-09-01 | 2014-10-01 | ClinicalTrials.gov |
| NCT01984619 | Prospective Study Evaluating the Treatment of Hyperdynamic Forehead Wrinkles | — | Wrinkles | Completed | 2013-09-01 | 2014-09-01 | ClinicalTrials.gov |
| NCT01919190 | EXPAREL Administered by Infiltration Into the TAP for Prolonged Postsurgical An… | Phase4 | Pain | Terminated | 2013-08-01 | 2014-02-01 | ClinicalTrials.gov |
| NCT01863901 | Study Evaluating Treatment of Upper Limb Spasticity Using the Cryo-Touch III De… | Na | Upper Limb Spasticity | Completed | 2013-04-01 | 2013-10-01 | ClinicalTrials.gov |
| NCT01801826 | A Prospective Study Evaluating the Treatment of Forehead and/or Glabellar Lines… | — | Frown Lines | Completed | 2013-01-01 | 2014-12-01 | ClinicalTrials.gov |
| NCT01802411 | Intercostal Nerve Block With Liposome Bupivacaine in Subjects Undergoing Poster… | Phase3 | Posterolateral Thoracotomy | Completed | 2012-12-01 | 2013-06-01 | ClinicalTrials.gov |
| NCT01753778 | Study Evaluating Treatment of Forefoot Pain Related to Nerve Entrapment Using t… | Na | Entrapment Neuropathy | Completed | 2012-11-01 | 2013-08-01 | ClinicalTrials.gov |
| NCT01808742 | Study Evaluating the Treatment of Forehead and/or Glabellar Lines With the CRYO… | — | Frown Lines | Completed | 2012-11-01 | 2014-08-01 | ClinicalTrials.gov |
| NCT02142829 | Pain Control in Bariatric Patients: EXPAREL(R) vs. the On-Q(R) Pain Ball | Phase4 | Obesity | Completed | 2012-11-01 | 2013-03-01 | ClinicalTrials.gov |
| NCT01753765 | Study Evaluating the Treatment of Occipital Neuralgia | Na | Occipital Neuralgia | Completed | 2012-10-01 | 2014-07-01 | ClinicalTrials.gov |
| NCT01683071 | Femoral Nerve Block With Liposome Bupivacaine for Postsurgical Analgesia Follow… | Phase2 | Postoperative Pain | Completed | 2012-09-01 | 2013-12-01 | ClinicalTrials.gov |
| NCT01704157 | A Prospective Study Evaluating the Treatment of Knee Osteoarthritis With the Cr… | Na | Osteoarthritis of the Knee | Completed | 2012-09-01 | 2013-07-01 | ClinicalTrials.gov |
| NCT01919606 | EXPAREL Administered Into the TAP for Analgesia in Subjects Undergoing Open Tot… | Phase4 | Postoperative Pain | Terminated | 2012-08-01 | 2012-10-01 | ClinicalTrials.gov |
| NCT01487200 | Pharmacokinetic and Pharmacodynamic Study of FX006 in Patients With Osteoarthri… | Phase2 | Osteoarthritis of the Knee | Completed | 2012-07-01 | 2012-11-01 | ClinicalTrials.gov |
| NCT01487161 | Study of FX006 in Patients With Osteoarthritis of the Knee | Phase2 | Osteoarthritis of the Knee | Completed | 2012-06-01 | 2013-04-01 | ClinicalTrials.gov |
| NCT01681745 | Probe Configuration and Time-Temperature Dose Ranging for Understanding of Skin… | Na | Histological Response of Tissue to Cold | Completed | 2012-06-01 | 2015-04-01 | ClinicalTrials.gov |
| NCT01507233 | A Health Economic Trial in Adult Patients Undergoing Open Colectomy MA402S23B302 | Phase4 | Bowel Obstruction | Terminated | 2012-05-01 | 2012-07-01 | ClinicalTrials.gov |
| NCT01582490 | Study of EXPAREL in Patients Undergoing Breast Augmentation | Phase4 | Mammoplasty | Completed | 2012-04-01 | 2012-11-01 | ClinicalTrials.gov |
| NCT01801124 | EXPAREL Infiltrated Into the TAP for Postoperative Analgesia in Unilateral Abdo… | Phase4 | Hernia | Completed | 2012-04-01 | 2012-12-01 | ClinicalTrials.gov |
| NCT01582477 | TAP-patients With Robotic Assisted Lap Prostatectomy | Phase4 | Postsurgical Pain | Completed | 2012-03-01 | 2012-07-01 | ClinicalTrials.gov |
| NCT01507220 | A Health Economic Trial in Adult Patients Undergoing Open Colectomy MA402S23B301 | Phase4 | Bowel Obstruction | Terminated | 2012-03-01 | 2012-07-01 | ClinicalTrials.gov |
| NCT01509638 | A Health Economic Trial in Adult Patients Undergoing Ileostomy Reversal MA402S2… | Phase4 | Retraction of Colostomy | Completed | 2012-03-01 | 2012-10-01 | ClinicalTrials.gov |
| NCT01349140 | EXPAREL Dose-Response for Single-Injection Femoral Nerve Blocks | Phase1 | Healthy Volunteers | Completed | 2012-02-01 | 2012-04-01 | ClinicalTrials.gov |
| NCT01509807 | A Health Economic Trial in Adult Patients Undergoing Ileostomy Reversal MA402S2… | Phase4 | Retraction of Colostomy | Completed | 2012-01-01 | 2012-10-01 | ClinicalTrials.gov |
| NCT01507246 | Adult Patients Undergoing Open Colectomy MA402S23B303 | Phase4 | Bowel Obstruction | Completed | 2011-12-01 | 2012-08-01 | ClinicalTrials.gov |
| NCT02058290 | A Health Economic Trial in Adult Patients Undergoing Laparoscopic Colectomy | Phase4 | Bowel Obstruction | Terminated | 2011-12-01 | 2013-02-01 | ClinicalTrials.gov |
| NCT01447342 | A Study to Evaluate the Safety and Effectiveness of the Cryo-Touch II Device fo… | Phase2 | Facial Wrinkles | Completed | 2011-09-01 | 2012-08-01 | ClinicalTrials.gov |
| NCT01379365 | Cryo-Touch III Refinement Study Investigational Plan | Phase2 | Facial Wrinkles | Completed | 2011-06-01 | 2014-12-01 | ClinicalTrials.gov |
| NCT01291914 | Study of FX005 for the Treatment of Pain in Patients With Osteoarthritis of the… | Phase1 | Osteoarthritis, Knee | Completed | 2010-12-01 | 2012-03-01 | ClinicalTrials.gov |
| NCT01167140 | Cryo-Touch II for the Treatment of Wrinkles | Phase2 | Facial Wrinkles | Completed | 2010-07-01 | 2011-04-01 | ClinicalTrials.gov |
| NCT01076686 | Observational Study to Assess Long-Term Follow-Up of Breast Augmentation Subjec… | — | Postoperative Pain | Completed | 2010-02-01 | 2010-03-01 | ClinicalTrials.gov |
| NCT00890721 | Study of Pain Control in Hemorrhoidectomy | Phase3 | Hemorrhoid | Completed | 2009-05-01 | 2009-11-01 | ClinicalTrials.gov |
| NCT00890682 | Study of Postoperative Analgesia in Bunionectomy | Phase3 | Bunion | Completed | 2009-04-01 | 2009-11-01 | ClinicalTrials.gov |
| NCT00842062 | Study of the MyoScience Tissue Remodeling Device for Facial Rejuvenation | Phase1 | Facial Rhytides | Completed | 2009-02-01 | 2012-01-01 | ClinicalTrials.gov |
| NCT00812305 | Hepatic Impairment Study: Pharmacokinetics in Healthy and Hepatically Impaired … | Phase1 | Pain | Completed | 2009-01-01 | 2009-08-01 | ClinicalTrials.gov |
| NCT00807209 | Dose Finding Posterolateral Thoracotomy Study | Phase2 | Postoperative Pain | Terminated | 2008-12-01 | 2009-02-01 | ClinicalTrials.gov |
| NCT00813111 | Phase 3 Study of Local Administration of SKY0402 for Postoperative Analgesia in… | Phase3 | Pain | Terminated | 2008-11-01 | 2009-02-01 | ClinicalTrials.gov |
| NCT00806806 | Evaluate the Onset of Action of SKY0402 Following Local Infiltration in Healthy… | Phase1 | Postoperative Pain Management | Completed | 2008-10-01 | 2009-02-01 | ClinicalTrials.gov |
| NCT00745290 | A Phase 3 Study to Evaluate the Safety and Efficacy of SKY0402 in Subjects Unde… | Phase3 | Postoperative Pain | Completed | 2008-08-01 | 2009-02-01 | ClinicalTrials.gov |
| NCT00744848 | Study to Evaluate Postoperative Analgesia in Subjects Undergoing Hemorrhoidecto… | Phase3 | Hemorrhoids | Completed | 2008-08-01 | 2009-02-01 | ClinicalTrials.gov |
| NCT01206608 | Evaluation of the Safety and Efficacy of a Single Dose of SKY0402 in Subjects U… | Phase2 | Postoperative Pain | Completed | 2008-03-01 | 2008-12-01 | ClinicalTrials.gov |
| NCT00529126 | Phase 2 Dose-Ranging Study of SKY0402 for Prolonged Postoperative Analgesia in … | Phase2 | Postoperative Pain | Completed | 2007-09-01 | 2008-07-01 | ClinicalTrials.gov |
| NCT00485693 | Dose-Ranging Study for Prolonged Postoperative Analgesia in Subject Undergoing … | Phase2 | Postoperative Pain | Completed | 2007-06-01 | 2009-08-01 | ClinicalTrials.gov |
| NCT00485667 | Phase 1 Thorough QT Study in Young Healthy Volunteers | Phase1 | Postoperative Pain | Completed | 2007-06-01 | 2007-08-01 | ClinicalTrials.gov |
| NCT00485433 | Dose-ranging Study for Postoperative Analgesia in Subjects Undergoing Primary U… | Phase2 | Postoperative Pain | Completed | 2007-06-01 | 2008-08-01 | ClinicalTrials.gov |
| NCT00130351 | A 3-week Study Investigating Patient Use and Functionality of Formoterol in a N… | Phase3 | Asthma | Completed | 2005-07-01 | 2005-08-01 | ClinicalTrials.gov |
| NCT01206595 | Safety, Efficacy, and Pharmacokinetics of SKY0402 Administered as a Nerve Block… | Phase2 | Postoperative Pain | Completed | 2005-03-01 | 2006-12-01 | ClinicalTrials.gov |
| NCT01203644 | Evaluation of the Safety, Efficacy, and Pharmacokinetics of SKY0402 in Subjects… | Phase2 | Inguinal Hernia | Completed | 2004-12-01 | 2006-12-01 | ClinicalTrials.gov |
| NCT00134979 | Formoterol Certihaler, Tiotropium HandiHaler and Tiotropium HandiHaler in Combi… | Phase4 | Chronic Obstructive Pulmonary Disease | Completed | 2004-10-01 | 2005-11-01 | ClinicalTrials.gov |
| NCT00728832 | A Pharmacokinetic (PK) Study of Extended-Release Epidural Morphine in Upper Abd… | Phase1 | Postoperative Pain | Completed | 2002-05-01 | — | ClinicalTrials.gov |
| NCT00029523 | DepoCyt Therapy in Patients With Neoplastic Meningitis From Lymphoma or a Solid… | Phase4 | Meningeal Neoplasms | Completed | 2001-04-01 | 2004-11-01 | ClinicalTrials.gov |
| NCT00003073 | Chemotherapy in Treating Young Patients With Recurrent or Refractory Meningeal … | Phase1 | Brain and Central Nervous System Tumors | Unknown | 1997-02-01 | — | ClinicalTrials.gov |
| Product Name | Type | Development Stage | Therapeutic Area | Study Status | Trial ID |
|---|---|---|---|---|---|
| Placebo | Other | Phase PHASE2 | Osteoarthritis (OA) of the Knee | RECRUITING | NCT06884865 |
| Enekinragene Inzadenovec (PCRX-201) | Other | Phase PHASE2 | Osteoarthritis (OA) of the Knee | RECRUITING | NCT06884865 |
| Treatment for Knee OA | Drug | Preclinical | Knee Osteoarthritis | RECRUITING | NCT05495334 |
| sham iovera° system treatment | Drug | Approved | Spasticity, Cerebral or Spinal Condition | ACTIVE_NOT_RECRUITING | NCT06340451 |
| iovera° system | Other | Approved | Spasticity, Cerebral or Spinal Condition | ACTIVE_NOT_RECRUITING | NCT06340451 |
| Radiofrequency ablation (RFA) | Other | Approved | Low Back Pain, Chronic | RECRUITING | NCT07214844 |
| Iovera Medial Branch Cryoneurolysis | Other | Approved | Low Back Pain, Chronic | RECRUITING | NCT07214844 |
| Treatment for Knee OA | Drug | Preclinical | Knee Osteoarthritis | RECRUITING | NCT05495334 |
| Treatment for Knee OA | Drug | Preclinical | Knee Osteoarthritis | RECRUITING | NCT05495334 |
| Placebo | Other | Phase PHASE3 | Glenohumeral Osteoarthritis | ACTIVE_NOT_RECRUITING | NCT06269705 |
| ZILRETTA | Other | Phase PHASE3 | Glenohumeral Osteoarthritis | ACTIVE_NOT_RECRUITING | NCT06269705 |
| Treatment for Knee OA | Drug | Preclinical | Knee Osteoarthritis | RECRUITING | NCT05495334 |
| Treatment for Knee OA | Drug | Preclinical | Knee Osteoarthritis | RECRUITING | NCT05495334 |
| Treatment for Knee OA | Drug | Preclinical | Knee Osteoarthritis | RECRUITING | NCT05495334 |
| Treatment for Knee OA | Drug | Preclinical | Knee Osteoarthritis | RECRUITING | NCT05495334 |
| Treatment for Knee OA | Drug | Preclinical | Knee Osteoarthritis | RECRUITING | NCT05495334 |
| Thoracic epidural analgesia (bupivacaine) | Other | Phase PHASE3 | Surgery | COMPLETED | NCT04117074 |
| Liposomal bupivacaine | Other | Phase PHASE3 | Surgery | COMPLETED | NCT04117074 |
| Thoracic epidural analgesia (bupivacaine) | Other | Phase PHASE3 | Surgery | COMPLETED | NCT04117074 |
| Liposomal bupivacaine | Other | Phase PHASE3 | Surgery | COMPLETED | NCT04117074 |
| Thoracic epidural analgesia (bupivacaine) | Other | Phase PHASE3 | Surgery | COMPLETED | NCT04117074 |
| Liposomal bupivacaine | Other | Phase PHASE3 | Surgery | COMPLETED | NCT04117074 |
| Thoracic epidural analgesia (bupivacaine) | Other | Phase PHASE3 | Surgery | COMPLETED | NCT04117074 |
| Liposomal bupivacaine | Other | Phase PHASE3 | Surgery | COMPLETED | NCT04117074 |
| Thoracic epidural analgesia (bupivacaine) | Other | Phase PHASE3 | Surgery | COMPLETED | NCT04117074 |
| Liposomal bupivacaine | Other | Phase PHASE3 | Surgery | COMPLETED | NCT04117074 |
| Thoracic epidural analgesia (bupivacaine) | Other | Phase PHASE3 | Surgery | COMPLETED | NCT04117074 |
| Liposomal bupivacaine | Other | Phase PHASE3 | Surgery | COMPLETED | NCT04117074 |
| Thoracic epidural analgesia (bupivacaine) | Other | Phase PHASE3 | Surgery | COMPLETED | NCT04117074 |
| Liposomal bupivacaine | Other | Phase PHASE3 | Surgery | COMPLETED | NCT04117074 |
| Thoracic epidural analgesia (bupivacaine) | Other | Phase PHASE3 | Surgery | COMPLETED | NCT04117074 |
| Liposomal bupivacaine | Other | Phase PHASE3 | Surgery | COMPLETED | NCT04117074 |
| Thoracic epidural analgesia (bupivacaine) | Other | Phase PHASE3 | Surgery | COMPLETED | NCT04117074 |
| Liposomal bupivacaine | Other | Phase PHASE3 | Surgery | COMPLETED | NCT04117074 |
| Thoracic epidural analgesia (bupivacaine) | Other | Phase PHASE3 | Surgery | COMPLETED | NCT04117074 |
| Liposomal bupivacaine | Other | Phase PHASE3 | Surgery | COMPLETED | NCT04117074 |
| Thoracic epidural analgesia (bupivacaine) | Other | Phase PHASE3 | Surgery | COMPLETED | NCT04117074 |
| Liposomal bupivacaine | Other | Phase PHASE3 | Surgery | COMPLETED | NCT04117074 |
| Thoracic epidural analgesia (bupivacaine) | Other | Phase PHASE3 | Surgery | COMPLETED | NCT04117074 |
| Liposomal bupivacaine | Other | Phase PHASE3 | Surgery | COMPLETED | NCT04117074 |
| Thoracic epidural analgesia (bupivacaine) | Other | Phase PHASE3 | Surgery | COMPLETED | NCT04117074 |
| Liposomal bupivacaine | Other | Phase PHASE3 | Surgery | COMPLETED | NCT04117074 |
| Thoracic epidural analgesia (bupivacaine) | Other | Phase PHASE3 | Surgery | COMPLETED | NCT04117074 |
| Liposomal bupivacaine | Other | Phase PHASE3 | Surgery | COMPLETED | NCT04117074 |
| Thoracic epidural analgesia (bupivacaine) | Other | Phase PHASE3 | Surgery | COMPLETED | NCT04117074 |
| Liposomal bupivacaine | Other | Phase PHASE3 | Surgery | COMPLETED | NCT04117074 |
| Thoracic epidural analgesia (bupivacaine) | Other | Phase PHASE3 | Surgery | COMPLETED | NCT04117074 |
| Liposomal bupivacaine | Other | Phase PHASE3 | Surgery | COMPLETED | NCT04117074 |
| Bupivacaine liposome injectable suspension (LIA) | Other | Phase PHASE4 | Total Knee Arthroplasty | ENROLLING_BY_INVITATION | NCT07584915 |
| Bupivacaine liposome injectable suspension (IPSA block) | Other | Phase PHASE4 | Total Knee Arthroplasty | ENROLLING_BY_INVITATION | NCT07584915 |
| Local Infiltration Analgesia (LIA) | Other | Phase PHASE4 | Total Knee Arthroplasty | ENROLLING_BY_INVITATION | NCT07584915 |
| Intra-articular Posteromedial Surgeon Administered (IPSA) Block with LIA | Other | Phase PHASE4 | Total Knee Arthroplasty | ENROLLING_BY_INVITATION | NCT07584915 |
| Bupivacaine liposome injectable suspension (LIA) | Other | Phase PHASE4 | Total Knee Arthroplasty | ENROLLING_BY_INVITATION | NCT07584915 |
| Bupivacaine liposome injectable suspension (IPSA block) | Other | Phase PHASE4 | Total Knee Arthroplasty | ENROLLING_BY_INVITATION | NCT07584915 |
| Local Infiltration Analgesia (LIA) | Other | Phase PHASE4 | Total Knee Arthroplasty | ENROLLING_BY_INVITATION | NCT07584915 |
| Intra-articular Posteromedial Surgeon Administered (IPSA) Block with LIA | Other | Phase PHASE4 | Total Knee Arthroplasty | ENROLLING_BY_INVITATION | NCT07584915 |
| Bupivacaine liposome injectable suspension (LIA) | Other | Phase PHASE4 | Total Knee Arthroplasty | ENROLLING_BY_INVITATION | NCT07584915 |
| Bupivacaine liposome injectable suspension (IPSA block) | Other | Phase PHASE4 | Total Knee Arthroplasty | ENROLLING_BY_INVITATION | NCT07584915 |
| Local Infiltration Analgesia (LIA) | Other | Phase PHASE4 | Total Knee Arthroplasty | ENROLLING_BY_INVITATION | NCT07584915 |
| Intra-articular Posteromedial Surgeon Administered (IPSA) Block with LIA | Other | Phase PHASE4 | Total Knee Arthroplasty | ENROLLING_BY_INVITATION | NCT07584915 |
| Bupivacaine liposome injectable suspension (LIA) | Other | Phase PHASE4 | Total Knee Arthroplasty | ENROLLING_BY_INVITATION | NCT07584915 |
| Bupivacaine liposome injectable suspension (IPSA block) | Other | Phase PHASE4 | Total Knee Arthroplasty | ENROLLING_BY_INVITATION | NCT07584915 |
| Local Infiltration Analgesia (LIA) | Other | Phase PHASE4 | Total Knee Arthroplasty | ENROLLING_BY_INVITATION | NCT07584915 |
| Intra-articular Posteromedial Surgeon Administered (IPSA) Block with LIA | Other | Phase PHASE4 | Total Knee Arthroplasty | ENROLLING_BY_INVITATION | NCT07584915 |
| Bupivacaine liposome injectable suspension (LIA) | Other | Phase PHASE4 | Total Knee Arthroplasty | ENROLLING_BY_INVITATION | NCT07584915 |
| Bupivacaine liposome injectable suspension (IPSA block) | Other | Phase PHASE4 | Total Knee Arthroplasty | ENROLLING_BY_INVITATION | NCT07584915 |
| Local Infiltration Analgesia (LIA) | Other | Phase PHASE4 | Total Knee Arthroplasty | ENROLLING_BY_INVITATION | NCT07584915 |
| Intra-articular Posteromedial Surgeon Administered (IPSA) Block with LIA | Other | Phase PHASE4 | Total Knee Arthroplasty | ENROLLING_BY_INVITATION | NCT07584915 |
| Cryoneurolysis | Other | Approved | ACL Repair | RECRUITING | NCT06603051 |
| Bupivacaine liposome injectable suspension (LIA) | Other | Phase PHASE4 | Total Knee Arthroplasty | ENROLLING_BY_INVITATION | NCT07584915 |
| Bupivacaine liposome injectable suspension (IPSA block) | Other | Phase PHASE4 | Total Knee Arthroplasty | ENROLLING_BY_INVITATION | NCT07584915 |
| Local Infiltration Analgesia (LIA) | Other | Phase PHASE4 | Total Knee Arthroplasty | ENROLLING_BY_INVITATION | NCT07584915 |
| Intra-articular Posteromedial Surgeon Administered (IPSA) Block with LIA | Other | Phase PHASE4 | Total Knee Arthroplasty | ENROLLING_BY_INVITATION | NCT07584915 |
| Cryoneurolysis | Other | Approved | ACL Repair | RECRUITING | NCT06603051 |
| Cryoneurolysis | Other | Approved | ACL Repair | RECRUITING | NCT06603051 |
| Cryoneurolysis | Other | Approved | ACL Repair | RECRUITING | NCT06603051 |
| Cryoneurolysis | Other | Approved | ACL Repair | RECRUITING | NCT06603051 |
| Cryoneurolysis | Other | Approved | ACL Repair | RECRUITING | NCT06603051 |
| Cryo-Touch III Device | Device | Approved | Entrapment Neuropathy | COMPLETED | NCT01753778 |
| EXPAREL | Other | Phase PHASE4 | Retraction of Colostomy | COMPLETED | NCT01509807 |
| IV morphine sulfate or Sponsor-approved equivalent | Other | Phase PHASE4 | Retraction of Colostomy | COMPLETED | NCT01509807 |
| EXPAREL | Other | Phase PHASE1 | Postoperative Pain Management | TERMINATED | NCT03428984 |
| EXPAREL 266 mg | Other | Phase PHASE2 | Postoperative Pain | COMPLETED | NCT01683071 |
| EXPAREL 133 mg | Other | Phase PHASE2 | Postoperative Pain | COMPLETED | NCT01683071 |
| EXPAREL 67 mg | Other | Phase PHASE2 | Postoperative Pain | COMPLETED | NCT01683071 |
| Placebo | Other | Phase PHASE2 | Postoperative Pain | COMPLETED | NCT01683071 |
| Bupivacaine HCl | Other | Phase PHASE2 | Postoperative Pain | COMPLETED | NCT01206595 |
| SKY0402 | Other | Phase PHASE2 | Postoperative Pain | COMPLETED | NCT01206595 |
| Bupivacaine HCl | Other | Phase PHASE2 | Inguinal Hernia | COMPLETED | NCT01203644 |
| SKY0402 | Other | Phase PHASE2 | Inguinal Hernia | COMPLETED | NCT01203644 |
| EXPAREL Infiltration | Other | Phase PHASE4 | Pain | COMPLETED | NCT02284386 |
| Bupivacaine SNB | Other | Phase PHASE4 | Pain | COMPLETED | NCT02284386 |
| Bupivacaine Hydrochloride | Other | Phase PHASE1 | Breast Augmentation | COMPLETED | NCT04293809 |
| Exparel Injectable Product | Other | Phase PHASE1 | Breast Augmentation | COMPLETED | NCT04293809 |
| Bupivacaine supraclavicular block | Other | Phase PHASE4 | Hand Injuries | TERMINATED | NCT02058303 |
| Exparel Forearm block | Other | Phase PHASE4 | Hand Injuries | TERMINATED | NCT02058303 |
| Questionnaire and Physical Exam | Other | Preclinical | Postoperative Pain | COMPLETED | NCT01076686 |
| EXPAREL (bupivacaine liposome injectable suspension) | Other | Phase PHASE4 | Bowel Obstruction | COMPLETED | NCT01507246 |
| IV morphine sulfate | Other | Phase PHASE4 | Bowel Obstruction | COMPLETED | NCT01507246 |
| Group 2 EXPAREL | Other | Phase PHASE4 | Retraction of Colostomy | COMPLETED | NCT01509638 |
| Group 1 Standard of Care | Other | Phase PHASE4 | Retraction of Colostomy | COMPLETED | NCT01509638 |
| EXPAREL (bupivacaine liposome injectable suspension) | Other | Phase PHASE4 | Bowel Obstruction | TERMINATED | NCT01507233 |
| IV morphine sulfate | Other | Phase PHASE4 | Bowel Obstruction | TERMINATED | NCT01507233 |
| bupivacaine liposome extended-release injectable suspension | Other | Phase PHASE4 | Bowel Obstruction | TERMINATED | NCT01507220 |
| morphine sulfate | Other | Phase PHASE4 | Bowel Obstruction | TERMINATED | NCT01507220 |
| EXPAREL | Other | Phase PHASE4 | Bowel Obstruction | TERMINATED | NCT02058290 |
| IV morphine sulfate or Sponsor-approved equivalent | Other | Phase PHASE4 | Bowel Obstruction | TERMINATED | NCT02058290 |
| On-Q Pain Ball | Other | Phase PHASE4 | Obesity | COMPLETED | NCT02142829 |
| EXPAREL | Other | Phase PHASE4 | Obesity | COMPLETED | NCT02142829 |
| Infiltration - EXPAREL | Other | Phase PHASE4 | Mammoplasty | COMPLETED | NCT01582490 |
| Instillation - EXPAREL | Other | Phase PHASE4 | Mammoplasty | COMPLETED | NCT01582490 |
| Cryotherapy for the utilization of wrinkle reduction (iovera) | Drug | Preclinical | Wrinkles | COMPLETED | NCT01984619 |
| iovera | Other | Approved | Forehead Wrinkles | COMPLETED | NCT01950065 |
| Treatment with CryoTouch III Device | Drug | Preclinical | Frown Lines | COMPLETED | NCT01808742 |
| Treatment with CryoTouch IV | Drug | Preclinical | Frown Lines | COMPLETED | NCT01801826 |
| Cryo-Touch II | Other | Phase PHASE2 | Facial Wrinkles | COMPLETED | NCT01447342 |
| Cryo-Touch III | Other | Phase PHASE2 | Facial Wrinkles | COMPLETED | NCT01379365 |
| Bupivacaine block in shoulder surgery | Procedure | Approved | Injury of Shoulder Region | COMPLETED | NCT02554357 |
| Exparel block in arthroscopic shoulder surgery | Procedure | Approved | Injury of Shoulder Region | COMPLETED | NCT02554357 |
| Continuous Perineural Ropivicaine Infusion | Other | Phase PHASE4 | Postoperative Pain | TERMINATED | NCT02787226 |
| Liposomal Bupivacaine Infiltration | Other | Phase PHASE4 | Postoperative Pain | TERMINATED | NCT02787226 |
| MRI | Other | Preclinical | Hematoma | COMPLETED | NCT02821325 |
| EXPAREL | Other | Phase PHASE1 | Spinal Fusion | COMPLETED | NCT02985762 |
| iovera° | Other | Approved | Anterior Cruciate Ligament Reconstruction | WITHDRAWN | NCT03688477 |
| iovera° | Other | Approved | ACL Reconstruction | WITHDRAWN | NCT03909516 |
| Bupivacaine Hcl 0.25% Inj | Other | Phase PHASE4 | Post Operative Pain | UNKNOWN | NCT03975283 |
| Exparel 266 MG Per 20 ML Injection | Other | Phase PHASE4 | Post Operative Pain | UNKNOWN | NCT03975283 |
| iovera° | Other | Approved | Arthropathy of Knee | WITHDRAWN | NCT03836313 |
| Ropivacaine | Other | Phase PHASE2 | Chronic Shoulder Pain | NOT_YET_RECRUITING | NCT03739021 |
| Exparel | Other | Phase PHASE2 | Chronic Shoulder Pain | NOT_YET_RECRUITING | NCT03739021 |
| Placebo | Other | Phase PHASE4 | Rotator Cuff Tear | COMPLETED | NCT03149887 |
| Liposomal bupivacaine | Other | Phase PHASE4 | Rotator Cuff Tear | COMPLETED | NCT03149887 |
| Bupivacaine Hydrochloride | Other | Phase PHASE4 | Hip Fractures | WITHDRAWN | NCT03955458 |
| Ropivacaine | Other | Phase PHASE4 | Hip Fractures | WITHDRAWN | NCT03955458 |
| EXPAREL | Other | Phase PHASE4 | Hip Fractures | WITHDRAWN | NCT03955458 |
| EXPAREL® infiltration | Other | Preclinical | Pain Management | WITHDRAWN | NCT03076710 |
| Opioids delivered through PCA | Other | Preclinical | Pain Management | WITHDRAWN | NCT03076710 |
| Bupivacaine Hydrochloride | Other | Phase PHASE3 | Bunion | WITHDRAWN | NCT03954639 |
| EXPAREL 13.3Mg/mL Suspension for Injection | Other | Phase PHASE3 | Bunion | WITHDRAWN | NCT03954639 |
| Liposome bupivacaine + bupivacaine | Other | Phase PHASE2 | Dupuytren's Contracture of the Hand (Viking's Disease) | COMPLETED | NCT03106519 |
| Liposome bupivacaine | Other | Phase PHASE2 | Hallux Valgus (Bunions) | COMPLETED | NCT03106545 |
| Exparel | Other | Phase PHASE4 | Ankle Arthrodesis | COMPLETED | NCT02586077 |
| Placebo | Other | Phase PHASE3 | Pain | COMPLETED | NCT02713178 |
| bupivacaine liposome injectable suspension | Other | Phase PHASE3 | Pain | COMPLETED | NCT02713178 |
| Placebo | Other | Phase PHASE3 | Pain | COMPLETED | NCT02713230 |
| bupivacaine liposome injectable suspension | Other | Phase PHASE3 | Pain | COMPLETED | NCT02713230 |
| Placebo | Other | Phase PHASE3 | Dental Pain | COMPLETED | NCT02517905 |
| Bupivacaine liposome | Other | Phase PHASE3 | Dental Pain | COMPLETED | NCT02517905 |
| Tranexamic Acid | Other | Phase PHASE2 | Total Knee Arthroplasty | TERMINATED | NCT02922582 |
| DepoTXA | Other | Phase PHASE2 | Total Knee Arthroplasty | TERMINATED | NCT02922582 |
| Bupivacaine | Other | Phase PHASE4 | Pain | COMPLETED | NCT02713490 |
| EXPAREL | Other | Phase PHASE4 | Pain | COMPLETED | NCT02713490 |
| Standard Bupivacaine | Other | Phase PHASE4 | Male Infertility | COMPLETED | NCT03802864 |
| Liposomal Bupivacaine | Other | Phase PHASE4 | Male Infertility | COMPLETED | NCT03802864 |
| 0.5% Bupivacaine HCl | Other | Phase PHASE3 | Postoperative Pain Management | COMPLETED | NCT03682302 |
| Exparel | Other | Phase PHASE3 | Postoperative Pain Management | COMPLETED | NCT03682302 |
| Bupivacaine | Other | Phase PHASE4 | C-Section | COMPLETED | NCT03176459 |
| Exparel + Bupivacaine | Other | Phase PHASE4 | C-Section | COMPLETED | NCT03176459 |
| Bupivacaine | Other | Phase PHASE1 | Bunion | COMPLETED | NCT04002089 |
| Exparel Injectable Product | Other | Phase PHASE1 | Bunion | COMPLETED | NCT04002089 |
| EXPAREL | Other | Phase PHASE4 | Postoperative Pain | TERMINATED | NCT01919606 |
| Mid-dose SKY0402 + bupivacaine HCl | Other | Phase PHASE2 | Postoperative Pain | COMPLETED | NCT01206608 |
| SKY0402 + bupivacaine HCl | Other | Phase PHASE2 | Postoperative Pain | COMPLETED | NCT01206608 |
| EXPAREL Infiltration | Other | Phase PHASE4 | Pain | COMPLETED | NCT02255500 |
| Bupivacaine FNB | Other | Phase PHASE4 | Pain | COMPLETED | NCT02255500 |
| EXPAREL | Other | Phase PHASE4 | Pain | COMPLETED | NCT02199574 |
| EXPAREL | Other | Phase PHASE4 | Hernia | COMPLETED | NCT01801124 |
| SKY0402 | Other | Phase PHASE1 | Healthy Volunteers | COMPLETED | NCT01349140 |
| EXPAREL | Other | Phase PHASE4 | Pain | TERMINATED | NCT02353754 |
| Intrathecal morphine injection | Other | Phase PHASE4 | Pain | TERMINATED | NCT02353754 |
| Placebo | Other | Phase PHASE1 | Healthy | TERMINATED | NCT04173611 |
| Bupivacaine Hydrochloride | Other | Phase PHASE1 | Healthy | TERMINATED | NCT04173611 |
| EXPAREL | Other | Phase PHASE1 | Healthy | TERMINATED | NCT04173611 |
| iovera° | Other | Approved | Total Knee Arthroplasty | COMPLETED | NCT03327220 |
| EXPAREL 40 mL | Other | Phase PHASE4 | Postsurgical Pain | COMPLETED | NCT01582477 |
| EXPAREL 20 mL | Other | Phase PHASE4 | Postsurgical Pain | COMPLETED | NCT01582477 |
| Placebo | Other | Phase PHASE4 | Pain | TERMINATED | NCT01919190 |
| EXPAREL | Other | Phase PHASE4 | Pain | TERMINATED | NCT01919190 |
| EXPAREL | Other | Phase PHASE1 | Healthy Volunteers | COMPLETED | NCT02210247 |
| Placebo | Other | Phase PHASE3 | Posterolateral Thoracotomy | COMPLETED | NCT01802411 |
| EXPAREL 266 mg | Other | Phase PHASE3 | Posterolateral Thoracotomy | COMPLETED | NCT01802411 |
| Bupivacaine Hydrochloride | Other | Phase PHASE3 | Coronary Artery Disease | COMPLETED | NCT03270514 |
| Exparel Injectable Product | Other | Phase PHASE3 | Coronary Artery Disease | COMPLETED | NCT03270514 |
| Placebo | Other | Phase PHASE4 | Analgesia, Postoperative | COMPLETED | NCT03541941 |
| Bupivacaine Hcl 0.25% Inj | Other | Phase PHASE4 | Analgesia, Postoperative | COMPLETED | NCT03541941 |
| Exparel | Other | Phase PHASE4 | Analgesia, Postoperative | COMPLETED | NCT03541941 |
| Bupivacaine HCl | Other | Phase PHASE4 | Postoperative Pain Management | TERMINATED | NCT03015961 |
| EXPAREL and bupivacaine HCl | Other | Phase PHASE4 | Postoperative Pain Management | TERMINATED | NCT03015961 |
| Bupivacaine Hydrochloride | Other | Phase PHASE4 | Vaginal Hysterectomy | TERMINATED | NCT03907033 |
| Liposomal bupivacaine | Other | Phase PHASE4 | Vaginal Hysterectomy | TERMINATED | NCT03907033 |
| Symptom Questionnaire | Other | Phase PHASE3 | Malignant Neoplasms of Female Genital Organs | TERMINATED | NCT02740114 |
| Pill Diary | Other | Phase PHASE3 | Malignant Neoplasms of Female Genital Organs | TERMINATED | NCT02740114 |
| Oxycodone | Other | Phase PHASE3 | Malignant Neoplasms of Female Genital Organs | TERMINATED | NCT02740114 |
| Liposomal Bupivacaine | Other | Phase PHASE3 | Malignant Neoplasms of Female Genital Organs | TERMINATED | NCT02740114 |
| Bupivacaine | Other | Phase PHASE3 | Malignant Neoplasms of Female Genital Organs | TERMINATED | NCT02740114 |
| Standard of Care | Other | Phase PHASE4 | Postoperative Pain Management | TERMINATED | NCT03927911 |
| EXPAREL and Bupivacaine | Other | Phase PHASE4 | Postoperative Pain Management | TERMINATED | NCT03927911 |
| Triamcinolone Acetonide Extended-Release Injectable Suspension | Other | Phase PHASE1 | Osteoarthritis, Knee | COMPLETED | NCT04261049 |
| Bupivacaine hydrochloride (HCl) | Other | Phase PHASE4 | Pain, Postoperative | COMPLETED | NCT04278846 |
| Depofoam bupivacaine | Other | Phase PHASE4 | Pain, Postoperative | COMPLETED | NCT04278846 |
| Bupivacaine Hydrochloride | Other | Phase PHASE3 | Lower Extremity Surgery | COMPLETED | NCT04518462 |
| Exparel | Other | Phase PHASE3 | Lower Extremity Surgery | COMPLETED | NCT04518462 |
| Exparel TAP + multi-modal pain regimen | Other | Phase PHASE4 | Elective Cesarean Section | COMPLETED | NCT03853694 |
| 150 mcg Duramorph + multi-modal pain regimen | Other | Phase PHASE4 | Elective Cesarean Section | COMPLETED | NCT03853694 |
| 50 mcg Duramorph+ EXPAREL + multi-modal pain regimen | Other | Phase PHASE4 | Elective Cesarean Section | COMPLETED | NCT03853694 |
| Normal Saline | Other | Phase PHASE1 | Pain, Postoperative | COMPLETED | NCT04826328 |
| FX301 | Other | Phase PHASE1 | Pain, Postoperative | COMPLETED | NCT04826328 |
| Cryoanalgesia (iovera°®) | Other | Approved | Morton's Neuroma | UNKNOWN | NCT05604144 |
| ioveraº sham | Other | Approved | Post-Operative Pain Management | TERMINATED | NCT04191031 |
| ioveraº | Other | Approved | Post-Operative Pain Management | TERMINATED | NCT04191031 |
| Sham cryoneurolysis procedure | Procedure | Approved | Mastectomy | COMPLETED | NCT03578237 |
| Cryoneurolysis (active) | Other | Approved | Mastectomy | COMPLETED | NCT03578237 |
| Exparel | Other | Phase PHASE1 | Postoperative Pain Management | COMPLETED | NCT03485014 |
| FX006 | Other | Phase PHASE2 | Trochanteric Bursitis | COMPLETED | NCT04182672 |
| Normal Saline | Other | Phase PHASE2 | Osteoarthritis of the Shoulder | TERMINATED | NCT04160091 |
| FX006 | Other | Phase PHASE2 | Osteoarthritis of the Shoulder | TERMINATED | NCT04160091 |
| FX006 32 mg | Other | Phase PHASE2 | Osteoarthritis, Hip | COMPLETED | NCT04065074 |
| Normal saline | Other | Phase PHASE3 | Osteoarthritis, Hip | TERMINATED | NCT03793010 |
| FX006 | Other | Phase PHASE3 | Osteoarthritis, Hip | TERMINATED | NCT03793010 |
| FX006 32 mg | Other | Phase PHASE3 | Osteoarthritis, Knee | COMPLETED | NCT03529942 |
| TAcs 40 mg | Other | Phase PHASE2 | Osteoarthritis of the Shoulder | COMPLETED | NCT03382262 |
| FX006 32 mg | Other | Phase PHASE2 | Osteoarthritis of the Shoulder | COMPLETED | NCT03382262 |
| TAcs 40 mg | Other | Phase PHASE2 | Bilateral Knee Osteoarthritis | COMPLETED | NCT03378076 |
| FX006 32 mg | Other | Phase PHASE2 | Bilateral Knee Osteoarthritis | COMPLETED | NCT03378076 |
| FX006 32 mg | Other | Phase PHASE3 | Osteoarthritis of the Knee | COMPLETED | NCT03046446 |
| TCA IR 40 mg | Other | Phase PHASE2 | Osteoarthritis of the Knee | COMPLETED | NCT02762370 |
| FX006 32 mg | Other | Phase PHASE2 | Osteoarthritis of the Knee | COMPLETED | NCT02762370 |
| TCA IR 40 | Other | Phase PHASE2 | Osteoarthritis of the Knee | COMPLETED | NCT02637323 |
| FX006 32 mg | Other | Phase PHASE2 | Osteoarthritis of the Knee | COMPLETED | NCT02637323 |
| TCA IR 40 mg | Other | Phase PHASE2 | Post-traumatic Osteoarthritis of the Knee | TERMINATED | NCT02468583 |
| FX006 32 mg | Other | Phase PHASE2 | Post-traumatic Osteoarthritis of the Knee | TERMINATED | NCT02468583 |
| TCA IR 40 | Other | Phase PHASE3 | Osteoarthritis of the Knee | COMPLETED | NCT02357459 |
| Placebo | Other | Phase PHASE3 | Osteoarthritis of the Knee | COMPLETED | NCT02357459 |
| FX006 | Other | Phase PHASE3 | Osteoarthritis of the Knee | COMPLETED | NCT02357459 |
| iovera° Sham | Other | Approved | Arthritis of the Knee | COMPLETED | NCT02284113 |
| iovera° | Other | Approved | Arthritis of the Knee | COMPLETED | NCT02284113 |
| Sham Comparator | Other | Approved | Knee Osteoarthritis | COMPLETED | NCT02260921 |
| iovera° | Other | Approved | Knee Osteoarthritis | COMPLETED | NCT02260921 |
| FX006 16 mg | Other | Phase PHASE2 | Osteoarthritis of the Knee | COMPLETED | NCT02116972 |
| Placebo | Other | Phase PHASE2 | Osteoarthritis of the Knee | COMPLETED | NCT02116972 |
| FX006 32 mg | Other | Phase PHASE2 | Osteoarthritis of the Knee | COMPLETED | NCT02116972 |
| TCA IR 40 mg | Other | Phase PHASE2 | Osteoarthritis of the Knee | COMPLETED | NCT02003365 |
| FX006 40 mg | Other | Phase PHASE2 | Osteoarthritis of the Knee | COMPLETED | NCT02003365 |
| FX006 10 mg | Other | Phase PHASE2 | Osteoarthritis of the Knee | COMPLETED | NCT02003365 |
| Treatment with Cryo-Touch III device | Drug | Approved | Upper Limb Spasticity | COMPLETED | NCT01863901 |
| Device: Cryo-Touch III Study treatment at Day 0. | Drug | Approved | Occipital Neuralgia | COMPLETED | NCT01753765 |
| Cryo-Touch III | Other | Approved | Osteoarthritis of the Knee | COMPLETED | NCT01704157 |
| Cryo-Touch III | Other | Approved | Histological Response of Tissue to Cold | COMPLETED | NCT01681745 |
| TCA IR 40 | Other | Phase PHASE2 | Osteoarthritis of the Knee | COMPLETED | NCT01487200 |
| FX006 60 mg | Other | Phase PHASE2 | Osteoarthritis of the Knee | COMPLETED | NCT01487200 |
| FX006 40 mg | Other | Phase PHASE2 | Osteoarthritis of the Knee | COMPLETED | NCT01487200 |
| FX006 10 mg | Other | Phase PHASE2 | Osteoarthritis of the Knee | COMPLETED | NCT01487200 |
| TCA IR | Other | Phase PHASE2 | Osteoarthritis of the Knee | COMPLETED | NCT01487161 |
| FX006 | Other | Phase PHASE2 | Osteoarthritis of the Knee | COMPLETED | NCT01487161 |
| Placebo 2 (Diluent) | Other | Phase PHASE1 | Osteoarthritis, Knee | COMPLETED | NCT01291914 |
| Placebo 1 (Carrier) | Other | Phase PHASE1 | Osteoarthritis, Knee | COMPLETED | NCT01291914 |
| FX005 | Other | Phase PHASE1 | Osteoarthritis, Knee | COMPLETED | NCT01291914 |
| Cryo-Touch II | Other | Phase PHASE2 | Facial Wrinkles | COMPLETED | NCT01167140 |
| Ropivacaine | Other | Phase PHASE4 | Rotator Cuff Injury | COMPLETED | NCT03738696 |
| Exparel | Other | Phase PHASE4 | Rotator Cuff Injury | COMPLETED | NCT03738696 |
| Liposomal bupivacaine (LB, Exparel) | Other | Phase PHASE4 | Adolescent Idiopathic Scoliosis | COMPLETED | NCT05730920 |
| Methadone | Other | Phase PHASE4 | Adolescent Idiopathic Scoliosis | COMPLETED | NCT05730920 |
| Bupivacaine Hydrochloride | Other | Phase PHASE3 | Knee Osteoarthritis | COMPLETED | NCT05139030 |
| bupivacaine liposome injectable suspension | Other | Phase PHASE3 | Knee Osteoarthritis | COMPLETED | NCT05139030 |
| Radiofrequency ablation | Other | Approved | Low Back Pain | COMPLETED | NCT06016127 |
| iovera system | Other | Approved | Low Back Pain | COMPLETED | NCT06016127 |
| Cryoneurolysis | Other | Approved | ACL Repair | RECRUITING | NCT06603051 |
| Bupivacain | Other | Phase PHASE2 | Back Pain | ENROLLING_BY_INVITATION | NCT06350981 |
| Exparel | Other | Phase PHASE2 | Back Pain | ENROLLING_BY_INVITATION | NCT06350981 |
| Acetaminophen 500Mg Cap | Other | Preclinical | ACL Tear | COMPLETED | NCT06340932 |
| Bupivacaine Hydrochloride | Other | Preclinical | ACL Tear | COMPLETED | NCT06340932 |
| Tramadol | Other | Preclinical | ACL Tear | COMPLETED | NCT06340932 |
| Oxycodone | Other | Preclinical | ACL Tear | COMPLETED | NCT06340932 |
| Acetaminophen | Other | Preclinical | ACL Tear | COMPLETED | NCT06340932 |
| Celecoxib | Other | Preclinical | ACL Tear | COMPLETED | NCT06340932 |
| Iovera | Other | Preclinical | ACL Tear | COMPLETED | NCT06340932 |
| Placebo | Other | Phase PHASE1 | Healthy | COMPLETED | NCT05456490 |
| Bupivacaine | Other | Phase PHASE1 | Healthy | COMPLETED | NCT05456490 |
| Liposomal Bupivacaine 13.3 | Other | Phase PHASE1 | Healthy | COMPLETED | NCT05456490 |
| FX201 | Other | Phase PHASE1 | Osteoarthritis, Knee | ACTIVE_NOT_RECRUITING | NCT04119687 |
| EXPAREL 1.3 % in 20 ML Injection | Other | Phase PHASE4 | Rotator Cuff Tear | TERMINATED | NCT03290196 |
| Radiofrequency ablation | Other | Approved | Chronic Sacroiliac Joint Pain | NOT_YET_RECRUITING | NCT06935539 |
| Cryoneurolysis | Other | Approved | Chronic Sacroiliac Joint Pain | NOT_YET_RECRUITING | NCT06935539 |
| Thoracic epidural analgesia (bupivacaine) | Other | Phase PHASE3 | Surgery | COMPLETED | NCT04117074 |
| Liposomal bupivacaine | Other | Phase PHASE3 | Surgery | COMPLETED | NCT04117074 |
| Bupivacaine liposome injectable suspension 133 mg | Other | Phase PHASE3 | Bunionectomy | COMPLETED | NCT05157841 |
| Bupivacaine HCl | Other | Phase PHASE3 | Bunionectomy | COMPLETED | NCT05157841 |
| Bupivacaine liposome injectable suspension 266 mg | Other | Phase PHASE3 | Bunionectomy | COMPLETED | NCT05157841 |
| Sham Cryoanalgesia | Other | Approved | Postoperative Pain | WITHDRAWN | NCT06284109 |
| Cryoanalgesia | Other | Approved | Postoperative Pain | WITHDRAWN | NCT06284109 |
| No cryoneurolysis | Other | Approved | Degenerative Joint Disease of Shoulder | RECRUITING | NCT07125833 |
| Cryoneurolysis | Other | Approved | Degenerative Joint Disease of Shoulder | RECRUITING | NCT07125833 |
| Local Infiltration Analgesia (LIA) of EXPAREL | Other | Approved | Total Knee Arthroplasty | RECRUITING | NCT06946368 |
| Adductor Canal Block (ACB) and Local Local Infiltration Analgesia of EXPAREL | Other | Approved | Total Knee Arthroplasty | RECRUITING | NCT06946368 |
| Intra-articular Posteromedial Surgeon Administered (IPSA) Block of EXPAREL | Other | Approved | Total Knee Arthroplasty | RECRUITING | NCT06946368 |
| an open surgery for abdominal hernia repair | Procedure | Phase PHASE4 | Pain | COMPLETED | NCT02128646 |
| laparoscopic abdominal hernia repair | Other | Phase PHASE4 | Pain | COMPLETED | NCT02128646 |
| Ketorolac | Other | Phase PHASE4 | Pain | COMPLETED | NCT02128646 |
| EXPAREL | Other | Phase PHASE4 | Pain | COMPLETED | NCT02128646 |
| Thoracic epidural analgesia | Other | Phase PHASE4 | Laparotomy | COMPLETED | NCT03827291 |
| Exparel | Other | Phase PHASE4 | Laparotomy | COMPLETED | NCT03827291 |
| Continuous popliteal nerve block with unencapsulated bupivacaine | Other | Phase PHASE4 | Moderate-to-severely Painful Ankle Surgery | ENROLLING_BY_INVITATION | NCT06995352 |
| Adductor canal nerve block with exclusively unencapsulated bupivacaine | Other | Phase PHASE4 | Moderate-to-severely Painful Ankle Surgery | ENROLLING_BY_INVITATION | NCT06995352 |
| Popliteal nerve block with exclusively unencapsulated bupivacaine | Other | Phase PHASE4 | Moderate-to-severely Painful Ankle Surgery | ENROLLING_BY_INVITATION | NCT06995352 |
| Continuous popliteal nerve block with normal saline | Other | Phase PHASE4 | Moderate-to-severely Painful Ankle Surgery | ENROLLING_BY_INVITATION | NCT06995352 |
| Adductor canal nerve block including liposomal bupivacaine | Other | Phase PHASE4 | Moderate-to-severely Painful Ankle Surgery | ENROLLING_BY_INVITATION | NCT06995352 |
| Popliteal nerve block including liposomal bupivacaine | Other | Phase PHASE4 | Moderate-to-severely Painful Ankle Surgery | ENROLLING_BY_INVITATION | NCT06995352 |
| Placebo | Other | Phase PHASE3 | Glenohumeral Osteoarthritis | RECRUITING | NCT06269705 |
| ZILRETTA | Other | Phase PHASE3 | Glenohumeral Osteoarthritis | RECRUITING | NCT06269705 |
| Triamcinolone Acetonide | Other | Phase PHASE2 | Osteoarthritis of Hip | TERMINATED | NCT06977568 |
| Zilretta | Other | Phase PHASE2 | Osteoarthritis of Hip | TERMINATED | NCT06977568 |
| bupivacaine | Other | Phase PHASE1 | Postoperative Pain | RECRUITING | NCT06271265 |
| EXPAREL | Other | Phase PHASE1 | Postoperative Pain | RECRUITING | NCT06271265 |
| Treatment for Knee OA | Drug | Preclinical | Knee Osteoarthritis | RECRUITING | NCT05495334 |
| Bupivacaine Hydrochloride | Other | Phase PHASE2 | Pain, Postoperative | ENROLLING_BY_INVITATION | NCT06077422 |
| bupivacaine liposome injectable suspension | Other | Phase PHASE2 | Pain, Postoperative | ENROLLING_BY_INVITATION | NCT06077422 |
| 0.25% bupivacaine (HCl): 30 ml | Other | Phase PHASE3 | Total Ankle Arthroplasty | RECRUITING | NCT07212114 |
| 0.25% bupivacaine (HCl): 50 ml | Other | Phase PHASE3 | Total Ankle Arthroplasty | RECRUITING | NCT07212114 |
| EXPAREL | Other | Phase PHASE3 | Total Ankle Arthroplasty | RECRUITING | NCT07212114 |
| ioveraº system | Other | Preclinical | Pain Management Improvement | COMPLETED | NCT06093776 |
| Placebo | Other | Phase PHASE2 | Osteoarthritis (OA) of the Knee | ACTIVE_NOT_RECRUITING | NCT06884865 |
| Enekinragene Inzadenovec (PCRX-201) | Other | Phase PHASE2 | Osteoarthritis (OA) of the Knee | ACTIVE_NOT_RECRUITING | NCT06884865 |
| sham iovera° system treatment | Drug | Approved | Spasticity, Cerebral or Spinal Condition | RECRUITING | NCT06340451 |
| iovera° system | Other | Approved | Spasticity, Cerebral or Spinal Condition | RECRUITING | NCT06340451 |
| Best Practices | Other | Phase PHASE3 | Knee Osteoarthritis | COMPLETED | NCT04504812 |
| Pain Coping Skills Training | Other | Phase PHASE3 | Knee Osteoarthritis | COMPLETED | NCT04504812 |
| Nerve Procedure with nerve ablation | Procedure | Phase PHASE3 | Knee Osteoarthritis | COMPLETED | NCT04504812 |
| Nerve Procedure with long acting blocks | Procedure | Phase PHASE3 | Knee Osteoarthritis | COMPLETED | NCT04504812 |
| Intra-Articular Injection | Other | Phase PHASE3 | Knee Osteoarthritis | COMPLETED | NCT04504812 |
| Duloxetine | Other | Phase PHASE3 | Knee Osteoarthritis | COMPLETED | NCT04504812 |
| Cryoneurolysis | Other | Approved | Spasticity as Sequela of Stroke | RECRUITING | NCT06958289 |
| Radiofrequency ablation (RFA) | Other | Approved | Low Back Pain, Chronic | RECRUITING | NCT07214844 |
| Iovera Medial Branch Cryoneurolysis | Other | Approved | Low Back Pain, Chronic | RECRUITING | NCT07214844 |
| Radiofrequency ablation (RFA) | Other | Approved | Low Back Pain, Chronic | RECRUITING | NCT07214844 |
| Iovera Medial Branch Cryoneurolysis | Other | Approved | Low Back Pain, Chronic | RECRUITING | NCT07214844 |
| Radiofrequency ablation (RFA) | Other | Approved | Low Back Pain, Chronic | RECRUITING | NCT07214844 |
| Iovera Medial Branch Cryoneurolysis | Other | Approved | Low Back Pain, Chronic | RECRUITING | NCT07214844 |
| Radiofrequency ablation (RFA) | Other | Approved | Low Back Pain, Chronic | RECRUITING | NCT07214844 |
| Iovera Medial Branch Cryoneurolysis | Other | Approved | Low Back Pain, Chronic | RECRUITING | NCT07214844 |
| Radiofrequency ablation (RFA) | Other | Approved | Low Back Pain, Chronic | RECRUITING | NCT07214844 |
| Iovera Medial Branch Cryoneurolysis | Other | Approved | Low Back Pain, Chronic | RECRUITING | NCT07214844 |
| Radiofrequency ablation (RFA) | Other | Approved | Low Back Pain, Chronic | RECRUITING | NCT07214844 |
| Iovera Medial Branch Cryoneurolysis | Other | Approved | Low Back Pain, Chronic | RECRUITING | NCT07214844 |
| Radiofrequency ablation (RFA) | Other | Approved | Low Back Pain, Chronic | RECRUITING | NCT07214844 |
| Iovera Medial Branch Cryoneurolysis | Other | Approved | Low Back Pain, Chronic | RECRUITING | NCT07214844 |
| Radiofrequency ablation (RFA) | Other | Approved | Low Back Pain, Chronic | RECRUITING | NCT07214844 |
| Iovera Medial Branch Cryoneurolysis | Other | Approved | Low Back Pain, Chronic | RECRUITING | NCT07214844 |
| Radiofrequency ablation (RFA) | Other | Approved | Low Back Pain, Chronic | RECRUITING | NCT07214844 |
| Iovera Medial Branch Cryoneurolysis | Other | Approved | Low Back Pain, Chronic | RECRUITING | NCT07214844 |
| Radiofrequency ablation (RFA) | Other | Approved | Low Back Pain, Chronic | RECRUITING | NCT07214844 |
| Iovera Medial Branch Cryoneurolysis | Other | Approved | Low Back Pain, Chronic | RECRUITING | NCT07214844 |
| Radiofrequency ablation (RFA) | Other | Approved | Low Back Pain, Chronic | RECRUITING | NCT07214844 |
| Iovera Medial Branch Cryoneurolysis | Other | Approved | Low Back Pain, Chronic | RECRUITING | NCT07214844 |
| Cryoneurolysis | Other | Approved | Spasticity as Sequela of Stroke | RECRUITING | NCT06958289 |
| Cryoneurolysis | Other | Approved | Spasticity as Sequela of Stroke | RECRUITING | NCT06958289 |
| Cryoneurolysis | Other | Approved | Spasticity as Sequela of Stroke | RECRUITING | NCT06958289 |
| Cryoneurolysis | Other | Approved | Spasticity as Sequela of Stroke | RECRUITING | NCT06958289 |
| Cryoneurolysis | Other | Approved | Spasticity as Sequela of Stroke | RECRUITING | NCT06958289 |
| Cryoneurolysis | Other | Approved | Spasticity as Sequela of Stroke | RECRUITING | NCT06958289 |