SymbolPCRX
NamePACIRA BIOSCIENCES, INC.
SectorHEALTH CARE
RegionNorth America
IndustryBiotechnology: Pharmaceutical Preparations
Address5401 WEST KENNEDY BOULEVARD,SUITE 890, TAMPA, Florida, 33609, United States
Telephone+1 813 553-6680
Fax
Email
Websitehttps://www.pacira.com
IncorporationUNDEFINED
Incorporated On
Employees
Fiscal Year
Public Since
ExchangesNASDAQ
Auditor
Audit StatusNOT PROVIDED
Reporting Status
CIK0001396814
Description

Pacira BioSciences Inc is a provider of non-opioid pain management and regenerative health solutions dedicated to advancing and improving outcomes for health care practitioners and their patients. The company has launched EXPAREL which utilizes DepoFoam, a product delivery technology that encapsulates drugs without altering their molecular structure, and releases them over a desired period of time.

Additional info from NASDAQ:
Pacira BioSciences Inc is a provider of non-opioid pain management and regenerative health solutions dedicated to advancing and improving outcomes for health care practitioners and their patients. The company has launched EXPAREL which utilizes DepoFoam, a product delivery technology that encapsulates drugs without altering their molecular structure, and releases them over a desired period of time.

2026-06-13 01:07

Director Hirawat Samit 🟢 acquired 17.3K shares (1 derivative) of Pacira BioSciences, Inc. (PCRX) at $23.42 Transaction Date: Jun 10, 2026 | Filing ID: 043010

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2026-06-13 01:07

RIKER LAUREN 🔴 sold 6.1K shares of Pacira BioSciences, Inc. (PCRX) at $23.50 Transaction Date: Jun 11, 2026 | Filing ID: 043009

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2026-06-13 01:07

Director CHRISTIE CHRISTOPHER 🟢 acquired 17.3K shares (1 derivative) of Pacira BioSciences, Inc. (PCRX) at $23.42 Transaction Date: Jun 10, 2026 | Filing ID: 043008

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2026-06-13 01:07

Director WIGGANS THOMAS G 🟢 acquired 32.7K shares (1 derivative) of Pacira BioSciences, Inc. (PCRX) at $23.42 Transaction Date: Jun 10, 2026 | Filing ID: 043007

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2026-06-13 01:07

Director Young Alethia 🟢 acquired 17.3K shares (1 derivative) of Pacira BioSciences, Inc. (PCRX) at $23.42 Transaction Date: Jun 10, 2026 | Filing ID: 043006

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2026-06-13 01:07

Director YANG MICHAEL J. 🟢 acquired 17.3K shares (1 derivative) of Pacira BioSciences, Inc. (PCRX) at $23.42 Transaction Date: Jun 10, 2026 | Filing ID: 043005

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2026-06-13 01:07

Director BIGAL MARCELO 🟢 acquired 17.3K shares (1 derivative) of Pacira BioSciences, Inc. (PCRX) at $23.42 Transaction Date: Jun 10, 2026 | Filing ID: 043004

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2026-06-13 01:06

Director Froimson Mark 🟢 acquired 17.3K shares (1 derivative) of Pacira BioSciences, Inc. (PCRX) at $23.42 Transaction Date: Jun 10, 2026 | Filing ID: 043003

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2026-06-13 01:06

Director Brege Laura 🟢 acquired 17.3K shares (1 derivative) of Pacira BioSciences, Inc. (PCRX) at $23.42 Transaction Date: Jun 10, 2026 | Filing ID: 043002

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2026-06-12 22:06

New Form 3 - Pacira BioSciences, Inc. <b>Filed:</b> 2026-06-12 <b>AccNo:</b> 0001628280-26-043001 <b>Size:</b> 9 KB

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Trial ID Title Phase Indication Status Start Date Completion Date Source
NCT07584915 Pilot Study on EXPAREL as an Intra-articular Posteromedial Surgeon Administered… Phase4 Total Knee Arthroplasty Enrolling_By_Invitation 2026-06-01 2026-08-01 ClinicalTrials.gov
NCT07214844 A Prospective Study to Evaluate the Efficacy of Iovera Lumbar Medial Branch Cry… Na Low Back Pain, Chronic Recruiting 2026-04-16 2028-05-01 ClinicalTrials.gov
NCT07212114 Efficacy of EXPAREL vs. Bupivacaine Phase3 Total Ankle Arthroplasty Recruiting 2025-11-17 2029-08-01 ClinicalTrials.gov
NCT06946368 Effectiveness of Exparel Anesthetic Administered by the Surgeon During Knee Sur… Na Total Knee Arthroplasty Recruiting 2025-08-18 2026-12-11 ClinicalTrials.gov
NCT06958289 Cryoneurolysis for Spasticity Treatment: Long-term Clinical Outcomes and Mechan… Na Spasticity as Sequela of Stroke Recruiting 2025-08-01 2028-05-01 ClinicalTrials.gov
NCT07125833 Cryoneurolysis of the Suprascapular Nerve for Perioperative Pain Control After … Na Degenerative Joint Disease of Shoulder Recruiting 2025-07-30 2026-08-01 ClinicalTrials.gov
NCT06977568 A Study to Evaluate an Intra-Articular Injection of ZILRETTA Versus Triamcinolo… Phase2 Osteoarthritis of Hip Terminated 2025-07-25 2025-10-16 ClinicalTrials.gov
NCT06995352 Liposomal Bupivacaine Versus Continuous Peripheral Nerve Blocks for Analgesia F… Phase4 Moderate-to-severely Painful Ankle Surgery Enrolling_By_Invitation 2025-06-23 2027-06-22 ClinicalTrials.gov
NCT06935539 Cryoneurolysis vs Radiofrequency Ablation for Chronic Sacroiliac Joint Pain Na Chronic Sacroiliac Joint Pain Not_Yet_Recruiting 2025-05-01 2026-08-01 ClinicalTrials.gov
NCT06884865 A Study to Assess Safety and Tolerability of PCRX-201 in Subjects With Painful … Phase2 Osteoarthritis (OA) of the Knee Active_Not_Recruiting 2025-02-26 2032-07-01 ClinicalTrials.gov
NCT06603051 The Effect of Pre-Operative Cryoneurolysis on Post-Operative Narcotic Consumpti… Na ACL Repair Recruiting 2024-08-28 2027-10-01 ClinicalTrials.gov
NCT06340451 Study to Assess the Efficacy and Safety of Iovera®° System in Subjects With Upp… Na Spasticity, Cerebral or Spinal Condition Recruiting 2024-07-11 2026-08-01 ClinicalTrials.gov
NCT06284109 Preoperative (Pre-amputation) Cryoanalgesia to Improve Post-amputation Phantom … Na Postoperative Pain Withdrawn 2024-06-01 2024-09-10 ClinicalTrials.gov
NCT06350981 Analgesic Requirement for Post-Operative Pain Control in TLIP Interbody Fusion Phase2 Back Pain Enrolling_By_Invitation 2024-04-30 2026-03-01 ClinicalTrials.gov
NCT06340932 Impact of Opioid Avoidance Protocol for ACL Reconstruction ACL Tear Completed 2024-04-27 2025-02-01 ClinicalTrials.gov
NCT06271265 Study to Evaluate the Pharmacokinetics and Safety of EXPAREL for Postoperative … Phase1 Postoperative Pain Recruiting 2024-03-29 2027-01-01 ClinicalTrials.gov
NCT06269705 ZILRETTA in Subjects With Shoulder Osteoarthritis Phase3 Glenohumeral Osteoarthritis Active_Not_Recruiting 2024-02-05 2026-12-01 ClinicalTrials.gov
NCT06077422 Exparel vs. Marcaine ESP Block for Post-cardiac Surgical Pain Phase2 Pain, Postoperative Enrolling_By_Invitation 2024-01-11 2027-04-05 ClinicalTrials.gov
NCT06093776 Rib Fracture Cryoanalgesia Pain Management Improvement Completed 2023-06-05 2025-06-12 ClinicalTrials.gov
NCT05456490 Phase 1, Dose Escalation Study to Evaluate of Safety, Pharmacokinetics and Phar… Phase1 Healthy Completed 2023-04-18 2025-02-27 ClinicalTrials.gov
NCT05730920 IV Methadone Vs EXPAREL Erector Spinae Plane Blockade in Pediatric Subjects Und… Phase4 Adolescent Idiopathic Scoliosis Completed 2022-10-19 2024-09-21 ClinicalTrials.gov
NCT05604144 Cryoanalgesia for the Treatment of Pain in Subjects With Morton's Neuroma Na Morton's Neuroma Unknown 2022-08-22 2023-04-22 ClinicalTrials.gov
NCT06016127 Cryoneurolysis for Facet Mediated Chronic Low Back Pain Na Low Back Pain Completed 2022-06-18 2023-10-23 ClinicalTrials.gov
NCT05157841 Phase 3, Sciatic Nerve Block With EXPAREL for Subjects Undergoing Bunionectomy Phase3 Bunionectomy Completed 2022-02-15 2022-08-17 ClinicalTrials.gov
NCT05139030 Phase 3 Adductor Canal Block With EXPAREL in Subjects Undergoing Primary Unilat… Phase3 Knee Osteoarthritis Completed 2022-01-18 2022-07-11 ClinicalTrials.gov
NCT05495334 Innovations in Genicular Outcomes Registry Knee Osteoarthritis Recruiting 2021-09-23 2033-12-30 ClinicalTrials.gov
NCT04117074 Thoracic Epidural Analgesia vs Surgical Site Infiltration With Liposomal Bupiva… Phase3 Surgery Completed 2021-04-14 2025-03-17 ClinicalTrials.gov
NCT04826328 Study to Evaluate the Safety and Tolerability of FX301 in Patients Undergoing B… Phase1 Pain, Postoperative Completed 2021-03-15 2022-03-30 ClinicalTrials.gov
NCT04504812 A Sequenced Strategy for Improving Outcomes in People With Knee Osteoarthritis … Phase3 Knee Osteoarthritis Completed 2021-02-01 2025-04-08 ClinicalTrials.gov
NCT04518462 Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of EXPAREL, EXPARE… Phase3 Lower Extremity Surgery Completed 2020-10-20 2021-04-05 ClinicalTrials.gov
NCT04191031 Study to Evaluate Iovera®° in Adult Patients Undergoing Total Knee Arthroplasty Na Post-Operative Pain Management Terminated 2020-09-30 2022-07-12 ClinicalTrials.gov
NCT04182672 Study to Assess the Safety and Efficacy of FX006 Administered to Patients With … Phase2 Trochanteric Bursitis Completed 2020-08-12 2022-12-14 ClinicalTrials.gov
NCT04261049 Effect of Zilretta Injection Phase1 Osteoarthritis, Knee Completed 2020-08-01 2022-01-10 ClinicalTrials.gov
NCT03954639 Phase 3, Randomized, Double Blinded, Active Controlled, Multicenter Study to Ev… Phase3 Bunion Withdrawn 2020-06-15 2020-09-01 ClinicalTrials.gov
NCT04173611 Evaluation of Safety, Pharmacokinetics and Pharmacodynamics of EXPAREL® Adminis… Phase1 Healthy Terminated 2020-06-08 2020-12-07 ClinicalTrials.gov
NCT04119687 Study to Evaluate the Safety and Tolerability of FX201 in Patients with Osteoar… Phase1 Osteoarthritis, Knee Active_Not_Recruiting 2020-03-02 2026-11-28 ClinicalTrials.gov
NCT04293809 Study to Evaluate the Pharmacokinetics and Safety of EXPAREL Administered as a … Phase1 Breast Augmentation Completed 2019-12-19 2020-01-29 ClinicalTrials.gov
NCT03738696 Liposomal Bupivacaine in Rotator Cuff Repair Phase4 Rotator Cuff Injury Completed 2019-12-15 2022-01-01 ClinicalTrials.gov
NCT04160091 Study to Evaluate the Efficacy and Safety of FX006 in Patients With Glenohumera… Phase2 Osteoarthritis of the Shoulder Terminated 2019-11-07 2020-06-15 ClinicalTrials.gov
NCT03739021 Exparel for Total Shoulder Pain Phase2 Chronic Shoulder Pain Not_Yet_Recruiting 2019-11-01 2020-11-15 ClinicalTrials.gov
NCT03827291 QL Block With Exparel in Colectomy Phase4 Laparotomy Completed 2019-10-31 2022-12-09 ClinicalTrials.gov
NCT03907033 Liposomal Bupivacaine in Vaginal Hysterectomy Phase4 Vaginal Hysterectomy Terminated 2019-09-03 2021-07-23 ClinicalTrials.gov
NCT03955458 EXPAREL Facia Iliaca Compartment Block for Intertrochanteric Hip Fracture Phase4 Hip Fractures Withdrawn 2019-08-26 2020-05-01 ClinicalTrials.gov
NCT03975283 Use of Exparel for Postoperative Analgesia Following Bariatric Surgery Phase4 Post Operative Pain Unknown 2019-08-01 2021-08-01 ClinicalTrials.gov
NCT03927911 Phase 4 Study in Adult Subjects Undergoing Posterior Lumbar Spine Surgeries Phase4 Postoperative Pain Management Terminated 2019-07-31 2020-08-04 ClinicalTrials.gov
NCT04065074 Study to Evaluate a Procedure for Intra-articular Injection of FX006 in Patient… Phase2 Osteoarthritis, Hip Completed 2019-07-30 2019-12-30 ClinicalTrials.gov
NCT04002089 Study to Evaluate the Pharmacokinetics, Pharmacodynamics and Safety, of EXPAREL… Phase1 Bunion Completed 2019-07-26 2019-12-02 ClinicalTrials.gov
NCT03909516 Evaluate the Iovera° Device in Treating Pain Associated With Anterior Cruciate … Na ACL Reconstruction Withdrawn 2019-05-01 2019-05-01 ClinicalTrials.gov
NCT03682302 Multicenter Study for Pediatric Subjects Evaluating Pharmacokinetics and Safety… Phase3 Postoperative Pain Management Completed 2019-04-02 2019-09-24 ClinicalTrials.gov
NCT03853694 Efficacy and Safety of EXPAREL Versus Standard of Care (SoC) in Subjects Underg… Phase4 Elective Cesarean Section Completed 2019-03-04 2020-01-16 ClinicalTrials.gov
NCT03836313 Assessing if Cryoneurolysis Improves Prehabilitation and Decreases Pain After S… Na Arthropathy of Knee Withdrawn 2019-03-01 2021-06-01 ClinicalTrials.gov
NCT03802864 Post-operative Pain Control of Testicular Sperm Extraction Using Liposomal Bupi… Phase4 Male Infertility Completed 2019-02-04 2020-01-30 ClinicalTrials.gov
NCT03793010 Study to Evaluate the Efficacy and Safety of FX006 in Patients With Hip Osteoar… Phase3 Osteoarthritis, Hip Terminated 2018-12-12 2019-08-07 ClinicalTrials.gov
NCT03270514 Comparison of Sternal Wound Infiltration With Liposomal Bupivacaine v. Bupivaca… Phase3 Coronary Artery Disease Completed 2018-11-15 2020-02-25 ClinicalTrials.gov
NCT03688477 Iovera° to Treat Pain Associated With ACL Reconstruction and Rehabilitation Na Anterior Cruciate Ligament Reconstruction Withdrawn 2018-10-01 2019-06-01 ClinicalTrials.gov
NCT03578237 Cryoanalgesia to Prevent Acute and Chronic Pain Following Surgery: A Randomized… Na Mastectomy Completed 2018-08-25 2022-11-25 ClinicalTrials.gov
NCT03541941 Exparel vs. Bupivacaine Hydrochloride vs. Placebo for Hernia Repair Phase4 Analgesia, Postoperative Completed 2018-07-03 2019-12-19 ClinicalTrials.gov
NCT03428984 Study in Adult Subjects Undergoing Posterolateral Thoracotomy Phase1 Postoperative Pain Management Terminated 2018-05-03 2018-09-28 ClinicalTrials.gov
NCT03529942 Study to Evaluate the Effect of FX006 on Synovial Inflammation in Patients With… Phase3 Osteoarthritis, Knee Completed 2018-04-24 2020-03-09 ClinicalTrials.gov
NCT03485014 Study in Pediatric Subjects Evaluating Pharmacokinetics and Safety of EXPAREL Phase1 Postoperative Pain Management Completed 2018-04-10 2019-02-12 ClinicalTrials.gov
NCT03382262 Study to Compare Exposure of TA Following Administration of FX006 or TAcs in Pa… Phase2 Osteoarthritis of the Shoulder Completed 2017-12-18 2018-10-09 ClinicalTrials.gov
NCT03378076 Study to Compare Exposure of TA Following Administration of Either FX006 or TAc… Phase2 Bilateral Knee Osteoarthritis Completed 2017-12-06 2018-03-14 ClinicalTrials.gov
NCT03149887 Liposomal Bupivacaine After Arthroscopic Rotator Cuff Repair Phase4 Rotator Cuff Tear Completed 2017-12-05 2019-03-01 ClinicalTrials.gov
NCT03327220 Treatment With Iovera° for Total Knee Arthroplasty (TKA) Post-Operative Pain Na Total Knee Arthroplasty Completed 2017-11-06 2019-03-27 ClinicalTrials.gov
NCT03076710 Post-Operative Pain Management Following Spine Surgery Pain Management Withdrawn 2017-07-31 2022-03-01 ClinicalTrials.gov
NCT03176459 Evaluate the Safety and Efficacy of EXPAREL When Administered Via Infiltration … Phase4 C-Section Completed 2017-06-01 2018-12-04 ClinicalTrials.gov
NCT03015961 Phase 4, Controlled Study in Adult Subjects Undergoing Primary, 1-2 Level, Open… Phase4 Postoperative Pain Management Terminated 2017-02-21 2017-10-30 ClinicalTrials.gov
NCT03046446 Study to Assess the Safety of Repeat Administration of FX006 Administered to Pa… Phase3 Osteoarthritis of the Knee Completed 2017-02-20 2018-07-19 ClinicalTrials.gov
NCT03106519 Liposome Bupivacaine for WRIST Blocks Phase2 Dupuytren's Contracture of the Hand (Viking's Disease) Completed 2017-01-02 2017-10-31 ClinicalTrials.gov
NCT03106545 Liposome Bupivacaine for ANKLE Blocks Phase2 Hallux Valgus (Bunions) Completed 2017-01-02 2017-10-31 ClinicalTrials.gov
NCT02985762 PK Study of EXPAREL in Subjects Undergoing Open Spinal Fusion or Reconstructive… Phase1 Spinal Fusion Completed 2016-12-01 2017-09-01 ClinicalTrials.gov
NCT02922582 Study of Local Administration of DepoTXA for Reduced Postsurgical Bleeding in S… Phase2 Total Knee Arthroplasty Terminated 2016-10-28 2017-11-27 ClinicalTrials.gov
NCT02821325 Intra-articular Volumetric Assessment After Total Knee Arthroplasty Hematoma Completed 2016-09-28 2018-01-30 ClinicalTrials.gov
NCT02740114 Wound Infiltration With Liposomal Bupivacaine vs. Standard Wound Infiltration W… Phase3 Malignant Neoplasms of Female Genital Organs Terminated 2016-08-31 2020-07-23 ClinicalTrials.gov
NCT02713178 Efficacy, Safety, and Pharmacokinetics of Femoral Nerve Block With EXPAREL in T… Phase3 Pain Completed 2016-06-03 2017-06-30 ClinicalTrials.gov
NCT02713230 Efficacy, Safety, and Pharmacokinetics of Brachial Plexus Block With EXPAREL in… Phase3 Pain Completed 2016-05-09 2017-07-07 ClinicalTrials.gov
NCT02713490 Local Infiltration Analgesia With and Without EXPAREL Following Total Knee Arth… Phase4 Pain Completed 2016-04-18 2017-02-08 ClinicalTrials.gov
NCT02762370 Study to Assess the Effects of FX006 on Blood Glucose in Patients With OA of th… Phase2 Osteoarthritis of the Knee Completed 2016-04-01 2016-11-01 ClinicalTrials.gov
NCT02637323 Study to Characterize the PK and Local Extent and Duration of Exposure From FX0… Phase2 Osteoarthritis of the Knee Completed 2015-11-01 2016-09-01 ClinicalTrials.gov
NCT03290196 The Effect of EXPAREL® on Postsurgical Pain, and the Use of Narcotics Phase4 Rotator Cuff Tear Terminated 2015-09-03 2022-04-07 ClinicalTrials.gov
NCT02517905 Evaluation of EXPAREL for Prolonged Postsurgical Analgesia in Subjects Undergoi… Phase3 Dental Pain Completed 2015-08-01 2016-01-01 ClinicalTrials.gov
NCT02554357 Quality of Analgesia After Interscalene Block After Arthroscopic Shoulder Surge… Na Injury of Shoulder Region Completed 2015-07-01 2016-03-01 ClinicalTrials.gov
NCT02353754 Evaluation of the Safety and Efficacy of EXPAREL When Administered Into the TAP… Phase4 Pain Terminated 2015-05-01 2015-07-01 ClinicalTrials.gov
NCT02468583 Proof of Concept Study Comparing FX006 to Kenalog®-40 in Patients With Post-Tra… Phase2 Post-traumatic Osteoarthritis of the Knee Terminated 2015-02-01 2016-07-01 ClinicalTrials.gov
NCT02357459 Study of FX006 for the Treatment of Pain in Patients With Osteoarthritis of the… Phase3 Osteoarthritis of the Knee Completed 2015-01-01 2016-01-01 ClinicalTrials.gov
NCT02284113 A Randomized, Study to Evaluate the Iovera° Device in Treating Pain Associated … Na Arthritis of the Knee Completed 2014-12-01 2016-06-01 ClinicalTrials.gov
NCT02284386 Pharmacokinetics and Safety of Bupivacaine HCl Spinal Block and EXPAREL Local I… Phase4 Pain Completed 2014-12-01 2015-03-01 ClinicalTrials.gov
NCT02260921 Study to Evaluate the Iovera° Device for Temporary Relief From Knee Pain Na Knee Osteoarthritis Completed 2014-10-20 2016-05-31 ClinicalTrials.gov
NCT02255500 EXPAREL Infiltration in Subjects Undergoing Femoral Nerve Block With Bupivacain… Phase4 Pain Completed 2014-09-01 2015-03-01 ClinicalTrials.gov
NCT04278846 Efficacy of Liposomal Bupivacaine for Prolonged Postoperative Analgesia in Pati… Phase4 Pain, Postoperative Completed 2014-08-22 2019-05-15 ClinicalTrials.gov
NCT02787226 Liposomal Bupivacaine Infiltration vs Continuous Perineural Ropivacaine Infusio… Phase4 Postoperative Pain Terminated 2014-08-01 2017-05-31 ClinicalTrials.gov
NCT02210247 Safety and Pharmacokinetics Study of Redosing EXPAREL in Healthy Volunteers Phase1 Healthy Volunteers Completed 2014-08-01 2014-09-01 ClinicalTrials.gov
NCT02199574 Pharmacokinetic Evaluation of EXPAREL in Adults Undergoing Tonsillectomy Phase4 Pain Completed 2014-08-01 2015-06-01 ClinicalTrials.gov
NCT02128646 Liposomal Bupivacaine (Exparel) for Postoperative Pain Control for Open and Lap… Phase4 Pain Completed 2014-04-01 2017-01-01 ClinicalTrials.gov
NCT02116972 Study of FX006 vs Normal Saline in Patients With Osteoarthritis of the Knee Phase2 Osteoarthritis of the Knee Completed 2014-04-01 2015-11-01 ClinicalTrials.gov
NCT02058303 Study of A Long Lasting Local Anesthestic for Hand, Wrist or Finger Surgery Phase4 Hand Injuries Terminated 2014-02-01 2016-03-01 ClinicalTrials.gov
NCT02586077 Foot and Ankle Clinic Application for Liposomal Related Anesthetic Phase4 Ankle Arthrodesis Completed 2014-02-01 2016-11-15 ClinicalTrials.gov
NCT02003365 Study to Characterize the Local Duration of Exposure From FX006 in Patients Wit… Phase2 Osteoarthritis of the Knee Completed 2013-11-01 2014-04-01 ClinicalTrials.gov
NCT01950065 Effectiveness and Safety Study of the Iovera Device for the Temporary Reduction… Na Forehead Wrinkles Completed 2013-09-01 2014-10-01 ClinicalTrials.gov
NCT01984619 Prospective Study Evaluating the Treatment of Hyperdynamic Forehead Wrinkles Wrinkles Completed 2013-09-01 2014-09-01 ClinicalTrials.gov
NCT01919190 EXPAREL Administered by Infiltration Into the TAP for Prolonged Postsurgical An… Phase4 Pain Terminated 2013-08-01 2014-02-01 ClinicalTrials.gov
NCT01863901 Study Evaluating Treatment of Upper Limb Spasticity Using the Cryo-Touch III De… Na Upper Limb Spasticity Completed 2013-04-01 2013-10-01 ClinicalTrials.gov
NCT01801826 A Prospective Study Evaluating the Treatment of Forehead and/or Glabellar Lines… Frown Lines Completed 2013-01-01 2014-12-01 ClinicalTrials.gov
NCT01802411 Intercostal Nerve Block With Liposome Bupivacaine in Subjects Undergoing Poster… Phase3 Posterolateral Thoracotomy Completed 2012-12-01 2013-06-01 ClinicalTrials.gov
NCT02142829 Pain Control in Bariatric Patients: EXPAREL(R) vs. the On-Q(R) Pain Ball Phase4 Obesity Completed 2012-11-01 2013-03-01 ClinicalTrials.gov
NCT01753778 Study Evaluating Treatment of Forefoot Pain Related to Nerve Entrapment Using t… Na Entrapment Neuropathy Completed 2012-11-01 2013-08-01 ClinicalTrials.gov
NCT01808742 Study Evaluating the Treatment of Forehead and/or Glabellar Lines With the CRYO… Frown Lines Completed 2012-11-01 2014-08-01 ClinicalTrials.gov
NCT01753765 Study Evaluating the Treatment of Occipital Neuralgia Na Occipital Neuralgia Completed 2012-10-01 2014-07-01 ClinicalTrials.gov
NCT01704157 A Prospective Study Evaluating the Treatment of Knee Osteoarthritis With the Cr… Na Osteoarthritis of the Knee Completed 2012-09-01 2013-07-01 ClinicalTrials.gov
NCT01683071 Femoral Nerve Block With Liposome Bupivacaine for Postsurgical Analgesia Follow… Phase2 Postoperative Pain Completed 2012-09-01 2013-12-01 ClinicalTrials.gov
NCT01919606 EXPAREL Administered Into the TAP for Analgesia in Subjects Undergoing Open Tot… Phase4 Postoperative Pain Terminated 2012-08-01 2012-10-01 ClinicalTrials.gov
NCT01487200 Pharmacokinetic and Pharmacodynamic Study of FX006 in Patients With Osteoarthri… Phase2 Osteoarthritis of the Knee Completed 2012-07-01 2012-11-01 ClinicalTrials.gov
NCT01487161 Study of FX006 in Patients With Osteoarthritis of the Knee Phase2 Osteoarthritis of the Knee Completed 2012-06-01 2013-04-01 ClinicalTrials.gov
NCT01681745 Probe Configuration and Time-Temperature Dose Ranging for Understanding of Skin… Na Histological Response of Tissue to Cold Completed 2012-06-01 2015-04-01 ClinicalTrials.gov
NCT01507233 A Health Economic Trial in Adult Patients Undergoing Open Colectomy MA402S23B302 Phase4 Bowel Obstruction Terminated 2012-05-01 2012-07-01 ClinicalTrials.gov
NCT01801124 EXPAREL Infiltrated Into the TAP for Postoperative Analgesia in Unilateral Abdo… Phase4 Hernia Completed 2012-04-01 2012-12-01 ClinicalTrials.gov
NCT01582490 Study of EXPAREL in Patients Undergoing Breast Augmentation Phase4 Mammoplasty Completed 2012-04-01 2012-11-01 ClinicalTrials.gov
NCT01509638 A Health Economic Trial in Adult Patients Undergoing Ileostomy Reversal MA402S2… Phase4 Retraction of Colostomy Completed 2012-03-01 2012-10-01 ClinicalTrials.gov
NCT01582477 TAP-patients With Robotic Assisted Lap Prostatectomy Phase4 Postsurgical Pain Completed 2012-03-01 2012-07-01 ClinicalTrials.gov
NCT01507220 A Health Economic Trial in Adult Patients Undergoing Open Colectomy MA402S23B301 Phase4 Bowel Obstruction Terminated 2012-03-01 2012-07-01 ClinicalTrials.gov
NCT01349140 EXPAREL Dose-Response for Single-Injection Femoral Nerve Blocks Phase1 Healthy Volunteers Completed 2012-02-01 2012-04-01 ClinicalTrials.gov
NCT01509807 A Health Economic Trial in Adult Patients Undergoing Ileostomy Reversal MA402S2… Phase4 Retraction of Colostomy Completed 2012-01-01 2012-10-01 ClinicalTrials.gov
NCT01507246 Adult Patients Undergoing Open Colectomy MA402S23B303 Phase4 Bowel Obstruction Completed 2011-12-01 2012-08-01 ClinicalTrials.gov
NCT02058290 A Health Economic Trial in Adult Patients Undergoing Laparoscopic Colectomy Phase4 Bowel Obstruction Terminated 2011-12-01 2013-02-01 ClinicalTrials.gov
NCT01447342 A Study to Evaluate the Safety and Effectiveness of the Cryo-Touch II Device fo… Phase2 Facial Wrinkles Completed 2011-09-01 2012-08-01 ClinicalTrials.gov
NCT01379365 Cryo-Touch III Refinement Study Investigational Plan Phase2 Facial Wrinkles Completed 2011-06-01 2014-12-01 ClinicalTrials.gov
NCT01291914 Study of FX005 for the Treatment of Pain in Patients With Osteoarthritis of the… Phase1 Osteoarthritis, Knee Completed 2010-12-01 2012-03-01 ClinicalTrials.gov
NCT01167140 Cryo-Touch II for the Treatment of Wrinkles Phase2 Facial Wrinkles Completed 2010-07-01 2011-04-01 ClinicalTrials.gov
NCT01076686 Observational Study to Assess Long-Term Follow-Up of Breast Augmentation Subjec… Postoperative Pain Completed 2010-02-01 2010-03-01 ClinicalTrials.gov
NCT00890721 Study of Pain Control in Hemorrhoidectomy Phase3 Hemorrhoid Completed 2009-05-01 2009-11-01 ClinicalTrials.gov
NCT00890682 Study of Postoperative Analgesia in Bunionectomy Phase3 Bunion Completed 2009-04-01 2009-11-01 ClinicalTrials.gov
NCT00842062 Study of the MyoScience Tissue Remodeling Device for Facial Rejuvenation Phase1 Facial Rhytides Completed 2009-02-01 2012-01-01 ClinicalTrials.gov
NCT00812305 Hepatic Impairment Study: Pharmacokinetics in Healthy and Hepatically Impaired … Phase1 Pain Completed 2009-01-01 2009-08-01 ClinicalTrials.gov
NCT00807209 Dose Finding Posterolateral Thoracotomy Study Phase2 Postoperative Pain Terminated 2008-12-01 2009-02-01 ClinicalTrials.gov
NCT00813111 Phase 3 Study of Local Administration of SKY0402 for Postoperative Analgesia in… Phase3 Pain Terminated 2008-11-01 2009-02-01 ClinicalTrials.gov
NCT00806806 Evaluate the Onset of Action of SKY0402 Following Local Infiltration in Healthy… Phase1 Postoperative Pain Management Completed 2008-10-01 2009-02-01 ClinicalTrials.gov
NCT00744848 Study to Evaluate Postoperative Analgesia in Subjects Undergoing Hemorrhoidecto… Phase3 Hemorrhoids Completed 2008-08-01 2009-02-01 ClinicalTrials.gov
NCT00745290 A Phase 3 Study to Evaluate the Safety and Efficacy of SKY0402 in Subjects Unde… Phase3 Postoperative Pain Completed 2008-08-01 2009-02-01 ClinicalTrials.gov
NCT01206608 Evaluation of the Safety and Efficacy of a Single Dose of SKY0402 in Subjects U… Phase2 Postoperative Pain Completed 2008-03-01 2008-12-01 ClinicalTrials.gov
NCT00529126 Phase 2 Dose-Ranging Study of SKY0402 for Prolonged Postoperative Analgesia in … Phase2 Postoperative Pain Completed 2007-09-01 2008-07-01 ClinicalTrials.gov
NCT00485693 Dose-Ranging Study for Prolonged Postoperative Analgesia in Subject Undergoing … Phase2 Postoperative Pain Completed 2007-06-01 2009-08-01 ClinicalTrials.gov
NCT00485667 Phase 1 Thorough QT Study in Young Healthy Volunteers Phase1 Postoperative Pain Completed 2007-06-01 2007-08-01 ClinicalTrials.gov
NCT00485433 Dose-ranging Study for Postoperative Analgesia in Subjects Undergoing Primary U… Phase2 Postoperative Pain Completed 2007-06-01 2008-08-01 ClinicalTrials.gov
NCT00130351 A 3-week Study Investigating Patient Use and Functionality of Formoterol in a N… Phase3 Asthma Completed 2005-07-01 2005-08-01 ClinicalTrials.gov
NCT01206595 Safety, Efficacy, and Pharmacokinetics of SKY0402 Administered as a Nerve Block… Phase2 Postoperative Pain Completed 2005-03-01 2006-12-01 ClinicalTrials.gov
NCT01203644 Evaluation of the Safety, Efficacy, and Pharmacokinetics of SKY0402 in Subjects… Phase2 Inguinal Hernia Completed 2004-12-01 2006-12-01 ClinicalTrials.gov
NCT00134979 Formoterol Certihaler, Tiotropium HandiHaler and Tiotropium HandiHaler in Combi… Phase4 Chronic Obstructive Pulmonary Disease Completed 2004-10-01 2005-11-01 ClinicalTrials.gov
NCT00728832 A Pharmacokinetic (PK) Study of Extended-Release Epidural Morphine in Upper Abd… Phase1 Postoperative Pain Completed 2002-05-01 ClinicalTrials.gov
NCT00029523 DepoCyt Therapy in Patients With Neoplastic Meningitis From Lymphoma or a Solid… Phase4 Meningeal Neoplasms Completed 2001-04-01 2004-11-01 ClinicalTrials.gov
NCT00003073 Chemotherapy in Treating Young Patients With Recurrent or Refractory Meningeal … Phase1 Brain and Central Nervous System Tumors Unknown 1997-02-01 ClinicalTrials.gov
Total clinical trials: 150
Product Name Type Development Stage Therapeutic Area Study Status Trial ID
Radiofrequency ablation (RFA) Other Approved Low Back Pain, Chronic RECRUITING NCT07214844
Iovera Medial Branch Cryoneurolysis Other Approved Low Back Pain, Chronic RECRUITING NCT07214844
Treatment for Knee OA Drug Preclinical Knee Osteoarthritis RECRUITING NCT05495334
Treatment for Knee OA Drug Preclinical Knee Osteoarthritis RECRUITING NCT05495334
Placebo Other Phase PHASE3 Glenohumeral Osteoarthritis ACTIVE_NOT_RECRUITING NCT06269705
ZILRETTA Other Phase PHASE3 Glenohumeral Osteoarthritis ACTIVE_NOT_RECRUITING NCT06269705
Treatment for Knee OA Drug Preclinical Knee Osteoarthritis RECRUITING NCT05495334
Treatment for Knee OA Drug Preclinical Knee Osteoarthritis RECRUITING NCT05495334
Treatment for Knee OA Drug Preclinical Knee Osteoarthritis RECRUITING NCT05495334
Treatment for Knee OA Drug Preclinical Knee Osteoarthritis RECRUITING NCT05495334
Treatment for Knee OA Drug Preclinical Knee Osteoarthritis RECRUITING NCT05495334
Thoracic epidural analgesia (bupivacaine) Other Phase PHASE3 Surgery COMPLETED NCT04117074
Liposomal bupivacaine Other Phase PHASE3 Surgery COMPLETED NCT04117074
Thoracic epidural analgesia (bupivacaine) Other Phase PHASE3 Surgery COMPLETED NCT04117074
Liposomal bupivacaine Other Phase PHASE3 Surgery COMPLETED NCT04117074
Thoracic epidural analgesia (bupivacaine) Other Phase PHASE3 Surgery COMPLETED NCT04117074
Liposomal bupivacaine Other Phase PHASE3 Surgery COMPLETED NCT04117074
Thoracic epidural analgesia (bupivacaine) Other Phase PHASE3 Surgery COMPLETED NCT04117074
Liposomal bupivacaine Other Phase PHASE3 Surgery COMPLETED NCT04117074
Thoracic epidural analgesia (bupivacaine) Other Phase PHASE3 Surgery COMPLETED NCT04117074
Liposomal bupivacaine Other Phase PHASE3 Surgery COMPLETED NCT04117074
Thoracic epidural analgesia (bupivacaine) Other Phase PHASE3 Surgery COMPLETED NCT04117074
Liposomal bupivacaine Other Phase PHASE3 Surgery COMPLETED NCT04117074
Thoracic epidural analgesia (bupivacaine) Other Phase PHASE3 Surgery COMPLETED NCT04117074
Liposomal bupivacaine Other Phase PHASE3 Surgery COMPLETED NCT04117074
Thoracic epidural analgesia (bupivacaine) Other Phase PHASE3 Surgery COMPLETED NCT04117074
Liposomal bupivacaine Other Phase PHASE3 Surgery COMPLETED NCT04117074
Thoracic epidural analgesia (bupivacaine) Other Phase PHASE3 Surgery COMPLETED NCT04117074
Liposomal bupivacaine Other Phase PHASE3 Surgery COMPLETED NCT04117074
Thoracic epidural analgesia (bupivacaine) Other Phase PHASE3 Surgery COMPLETED NCT04117074
Liposomal bupivacaine Other Phase PHASE3 Surgery COMPLETED NCT04117074
Thoracic epidural analgesia (bupivacaine) Other Phase PHASE3 Surgery COMPLETED NCT04117074
Liposomal bupivacaine Other Phase PHASE3 Surgery COMPLETED NCT04117074
Thoracic epidural analgesia (bupivacaine) Other Phase PHASE3 Surgery COMPLETED NCT04117074
Liposomal bupivacaine Other Phase PHASE3 Surgery COMPLETED NCT04117074
Thoracic epidural analgesia (bupivacaine) Other Phase PHASE3 Surgery COMPLETED NCT04117074
Liposomal bupivacaine Other Phase PHASE3 Surgery COMPLETED NCT04117074
Thoracic epidural analgesia (bupivacaine) Other Phase PHASE3 Surgery COMPLETED NCT04117074
Liposomal bupivacaine Other Phase PHASE3 Surgery COMPLETED NCT04117074
Thoracic epidural analgesia (bupivacaine) Other Phase PHASE3 Surgery COMPLETED NCT04117074
Liposomal bupivacaine Other Phase PHASE3 Surgery COMPLETED NCT04117074
Thoracic epidural analgesia (bupivacaine) Other Phase PHASE3 Surgery COMPLETED NCT04117074
Liposomal bupivacaine Other Phase PHASE3 Surgery COMPLETED NCT04117074
Bupivacaine liposome injectable suspension (LIA) Other Phase PHASE4 Total Knee Arthroplasty ENROLLING_BY_INVITATION NCT07584915
Bupivacaine liposome injectable suspension (IPSA block) Other Phase PHASE4 Total Knee Arthroplasty ENROLLING_BY_INVITATION NCT07584915
Local Infiltration Analgesia (LIA) Other Phase PHASE4 Total Knee Arthroplasty ENROLLING_BY_INVITATION NCT07584915
Intra-articular Posteromedial Surgeon Administered (IPSA) Block with LIA Other Phase PHASE4 Total Knee Arthroplasty ENROLLING_BY_INVITATION NCT07584915
Bupivacaine liposome injectable suspension (LIA) Other Phase PHASE4 Total Knee Arthroplasty ENROLLING_BY_INVITATION NCT07584915
Bupivacaine liposome injectable suspension (IPSA block) Other Phase PHASE4 Total Knee Arthroplasty ENROLLING_BY_INVITATION NCT07584915
Local Infiltration Analgesia (LIA) Other Phase PHASE4 Total Knee Arthroplasty ENROLLING_BY_INVITATION NCT07584915
Intra-articular Posteromedial Surgeon Administered (IPSA) Block with LIA Other Phase PHASE4 Total Knee Arthroplasty ENROLLING_BY_INVITATION NCT07584915
Bupivacaine liposome injectable suspension (LIA) Other Phase PHASE4 Total Knee Arthroplasty ENROLLING_BY_INVITATION NCT07584915
Bupivacaine liposome injectable suspension (IPSA block) Other Phase PHASE4 Total Knee Arthroplasty ENROLLING_BY_INVITATION NCT07584915
Local Infiltration Analgesia (LIA) Other Phase PHASE4 Total Knee Arthroplasty ENROLLING_BY_INVITATION NCT07584915
Intra-articular Posteromedial Surgeon Administered (IPSA) Block with LIA Other Phase PHASE4 Total Knee Arthroplasty ENROLLING_BY_INVITATION NCT07584915
Bupivacaine liposome injectable suspension (LIA) Other Phase PHASE4 Total Knee Arthroplasty ENROLLING_BY_INVITATION NCT07584915
Bupivacaine liposome injectable suspension (IPSA block) Other Phase PHASE4 Total Knee Arthroplasty ENROLLING_BY_INVITATION NCT07584915
Local Infiltration Analgesia (LIA) Other Phase PHASE4 Total Knee Arthroplasty ENROLLING_BY_INVITATION NCT07584915
Intra-articular Posteromedial Surgeon Administered (IPSA) Block with LIA Other Phase PHASE4 Total Knee Arthroplasty ENROLLING_BY_INVITATION NCT07584915
Bupivacaine liposome injectable suspension (LIA) Other Phase PHASE4 Total Knee Arthroplasty ENROLLING_BY_INVITATION NCT07584915
Bupivacaine liposome injectable suspension (IPSA block) Other Phase PHASE4 Total Knee Arthroplasty ENROLLING_BY_INVITATION NCT07584915
Local Infiltration Analgesia (LIA) Other Phase PHASE4 Total Knee Arthroplasty ENROLLING_BY_INVITATION NCT07584915
Intra-articular Posteromedial Surgeon Administered (IPSA) Block with LIA Other Phase PHASE4 Total Knee Arthroplasty ENROLLING_BY_INVITATION NCT07584915
Cryoneurolysis Other Approved ACL Repair RECRUITING NCT06603051
Bupivacaine liposome injectable suspension (LIA) Other Phase PHASE4 Total Knee Arthroplasty ENROLLING_BY_INVITATION NCT07584915
Bupivacaine liposome injectable suspension (IPSA block) Other Phase PHASE4 Total Knee Arthroplasty ENROLLING_BY_INVITATION NCT07584915
Local Infiltration Analgesia (LIA) Other Phase PHASE4 Total Knee Arthroplasty ENROLLING_BY_INVITATION NCT07584915
Intra-articular Posteromedial Surgeon Administered (IPSA) Block with LIA Other Phase PHASE4 Total Knee Arthroplasty ENROLLING_BY_INVITATION NCT07584915
Cryoneurolysis Other Approved ACL Repair RECRUITING NCT06603051
Cryoneurolysis Other Approved ACL Repair RECRUITING NCT06603051
Cryoneurolysis Other Approved ACL Repair RECRUITING NCT06603051
Cryoneurolysis Other Approved ACL Repair RECRUITING NCT06603051
Cryoneurolysis Other Approved ACL Repair RECRUITING NCT06603051
Cryo-Touch III Device Device Approved Entrapment Neuropathy COMPLETED NCT01753778
EXPAREL Other Phase PHASE4 Retraction of Colostomy COMPLETED NCT01509807
IV morphine sulfate or Sponsor-approved equivalent Other Phase PHASE4 Retraction of Colostomy COMPLETED NCT01509807
EXPAREL Other Phase PHASE1 Postoperative Pain Management TERMINATED NCT03428984
EXPAREL 266 mg Other Phase PHASE2 Postoperative Pain COMPLETED NCT01683071
EXPAREL 133 mg Other Phase PHASE2 Postoperative Pain COMPLETED NCT01683071
EXPAREL 67 mg Other Phase PHASE2 Postoperative Pain COMPLETED NCT01683071
Placebo Other Phase PHASE2 Postoperative Pain COMPLETED NCT01683071
Bupivacaine HCl Other Phase PHASE2 Postoperative Pain COMPLETED NCT01206595
SKY0402 Other Phase PHASE2 Postoperative Pain COMPLETED NCT01206595
Bupivacaine HCl Other Phase PHASE2 Inguinal Hernia COMPLETED NCT01203644
SKY0402 Other Phase PHASE2 Inguinal Hernia COMPLETED NCT01203644
EXPAREL Infiltration Other Phase PHASE4 Pain COMPLETED NCT02284386
Bupivacaine SNB Other Phase PHASE4 Pain COMPLETED NCT02284386
Bupivacaine Hydrochloride Other Phase PHASE1 Breast Augmentation COMPLETED NCT04293809
Exparel Injectable Product Other Phase PHASE1 Breast Augmentation COMPLETED NCT04293809
Bupivacaine supraclavicular block Other Phase PHASE4 Hand Injuries TERMINATED NCT02058303
Exparel Forearm block Other Phase PHASE4 Hand Injuries TERMINATED NCT02058303
Questionnaire and Physical Exam Other Preclinical Postoperative Pain COMPLETED NCT01076686
EXPAREL (bupivacaine liposome injectable suspension) Other Phase PHASE4 Bowel Obstruction COMPLETED NCT01507246
IV morphine sulfate Other Phase PHASE4 Bowel Obstruction COMPLETED NCT01507246
Group 2 EXPAREL Other Phase PHASE4 Retraction of Colostomy COMPLETED NCT01509638
Group 1 Standard of Care Other Phase PHASE4 Retraction of Colostomy COMPLETED NCT01509638
EXPAREL (bupivacaine liposome injectable suspension) Other Phase PHASE4 Bowel Obstruction TERMINATED NCT01507233
IV morphine sulfate Other Phase PHASE4 Bowel Obstruction TERMINATED NCT01507233
bupivacaine liposome extended-release injectable suspension Other Phase PHASE4 Bowel Obstruction TERMINATED NCT01507220
morphine sulfate Other Phase PHASE4 Bowel Obstruction TERMINATED NCT01507220
EXPAREL Other Phase PHASE4 Bowel Obstruction TERMINATED NCT02058290
IV morphine sulfate or Sponsor-approved equivalent Other Phase PHASE4 Bowel Obstruction TERMINATED NCT02058290
On-Q Pain Ball Other Phase PHASE4 Obesity COMPLETED NCT02142829
EXPAREL Other Phase PHASE4 Obesity COMPLETED NCT02142829
Infiltration - EXPAREL Other Phase PHASE4 Mammoplasty COMPLETED NCT01582490
Instillation - EXPAREL Other Phase PHASE4 Mammoplasty COMPLETED NCT01582490
Cryotherapy for the utilization of wrinkle reduction (iovera) Drug Preclinical Wrinkles COMPLETED NCT01984619
iovera Other Approved Forehead Wrinkles COMPLETED NCT01950065
Treatment with CryoTouch III Device Drug Preclinical Frown Lines COMPLETED NCT01808742
Treatment with CryoTouch IV Drug Preclinical Frown Lines COMPLETED NCT01801826
Cryo-Touch II Other Phase PHASE2 Facial Wrinkles COMPLETED NCT01447342
Cryo-Touch III Other Phase PHASE2 Facial Wrinkles COMPLETED NCT01379365
Bupivacaine block in shoulder surgery Procedure Approved Injury of Shoulder Region COMPLETED NCT02554357
Exparel block in arthroscopic shoulder surgery Procedure Approved Injury of Shoulder Region COMPLETED NCT02554357
Continuous Perineural Ropivicaine Infusion Other Phase PHASE4 Postoperative Pain TERMINATED NCT02787226
Liposomal Bupivacaine Infiltration Other Phase PHASE4 Postoperative Pain TERMINATED NCT02787226
MRI Other Preclinical Hematoma COMPLETED NCT02821325
EXPAREL Other Phase PHASE1 Spinal Fusion COMPLETED NCT02985762
iovera° Other Approved Anterior Cruciate Ligament Reconstruction WITHDRAWN NCT03688477
iovera° Other Approved ACL Reconstruction WITHDRAWN NCT03909516
Bupivacaine Hcl 0.25% Inj Other Phase PHASE4 Post Operative Pain UNKNOWN NCT03975283
Exparel 266 MG Per 20 ML Injection Other Phase PHASE4 Post Operative Pain UNKNOWN NCT03975283
iovera° Other Approved Arthropathy of Knee WITHDRAWN NCT03836313
Ropivacaine Other Phase PHASE2 Chronic Shoulder Pain NOT_YET_RECRUITING NCT03739021
Exparel Other Phase PHASE2 Chronic Shoulder Pain NOT_YET_RECRUITING NCT03739021
Placebo Other Phase PHASE4 Rotator Cuff Tear COMPLETED NCT03149887
Liposomal bupivacaine Other Phase PHASE4 Rotator Cuff Tear COMPLETED NCT03149887
Bupivacaine Hydrochloride Other Phase PHASE4 Hip Fractures WITHDRAWN NCT03955458
Ropivacaine Other Phase PHASE4 Hip Fractures WITHDRAWN NCT03955458
EXPAREL Other Phase PHASE4 Hip Fractures WITHDRAWN NCT03955458
EXPAREL® infiltration Other Preclinical Pain Management WITHDRAWN NCT03076710
Opioids delivered through PCA Other Preclinical Pain Management WITHDRAWN NCT03076710
Bupivacaine Hydrochloride Other Phase PHASE3 Bunion WITHDRAWN NCT03954639
EXPAREL 13.3Mg/mL Suspension for Injection Other Phase PHASE3 Bunion WITHDRAWN NCT03954639
Liposome bupivacaine + bupivacaine Other Phase PHASE2 Dupuytren's Contracture of the Hand (Viking's Disease) COMPLETED NCT03106519
Liposome bupivacaine Other Phase PHASE2 Hallux Valgus (Bunions) COMPLETED NCT03106545
Exparel Other Phase PHASE4 Ankle Arthrodesis COMPLETED NCT02586077
Placebo Other Phase PHASE3 Pain COMPLETED NCT02713178
bupivacaine liposome injectable suspension Other Phase PHASE3 Pain COMPLETED NCT02713178
Placebo Other Phase PHASE3 Pain COMPLETED NCT02713230
bupivacaine liposome injectable suspension Other Phase PHASE3 Pain COMPLETED NCT02713230
Placebo Other Phase PHASE3 Dental Pain COMPLETED NCT02517905
Bupivacaine liposome Other Phase PHASE3 Dental Pain COMPLETED NCT02517905
Tranexamic Acid Other Phase PHASE2 Total Knee Arthroplasty TERMINATED NCT02922582
DepoTXA Other Phase PHASE2 Total Knee Arthroplasty TERMINATED NCT02922582
Bupivacaine Other Phase PHASE4 Pain COMPLETED NCT02713490
EXPAREL Other Phase PHASE4 Pain COMPLETED NCT02713490
Standard Bupivacaine Other Phase PHASE4 Male Infertility COMPLETED NCT03802864
Liposomal Bupivacaine Other Phase PHASE4 Male Infertility COMPLETED NCT03802864
0.5% Bupivacaine HCl Other Phase PHASE3 Postoperative Pain Management COMPLETED NCT03682302
Exparel Other Phase PHASE3 Postoperative Pain Management COMPLETED NCT03682302
Bupivacaine Other Phase PHASE4 C-Section COMPLETED NCT03176459
Exparel + Bupivacaine Other Phase PHASE4 C-Section COMPLETED NCT03176459
Bupivacaine Other Phase PHASE1 Bunion COMPLETED NCT04002089
Exparel Injectable Product Other Phase PHASE1 Bunion COMPLETED NCT04002089
EXPAREL Other Phase PHASE4 Postoperative Pain TERMINATED NCT01919606
Mid-dose SKY0402 + bupivacaine HCl Other Phase PHASE2 Postoperative Pain COMPLETED NCT01206608
SKY0402 + bupivacaine HCl Other Phase PHASE2 Postoperative Pain COMPLETED NCT01206608
EXPAREL Infiltration Other Phase PHASE4 Pain COMPLETED NCT02255500
Bupivacaine FNB Other Phase PHASE4 Pain COMPLETED NCT02255500
EXPAREL Other Phase PHASE4 Pain COMPLETED NCT02199574
EXPAREL Other Phase PHASE4 Hernia COMPLETED NCT01801124
SKY0402 Other Phase PHASE1 Healthy Volunteers COMPLETED NCT01349140
EXPAREL Other Phase PHASE4 Pain TERMINATED NCT02353754
Intrathecal morphine injection Other Phase PHASE4 Pain TERMINATED NCT02353754
Placebo Other Phase PHASE1 Healthy TERMINATED NCT04173611
Bupivacaine Hydrochloride Other Phase PHASE1 Healthy TERMINATED NCT04173611
EXPAREL Other Phase PHASE1 Healthy TERMINATED NCT04173611
iovera° Other Approved Total Knee Arthroplasty COMPLETED NCT03327220
EXPAREL 40 mL Other Phase PHASE4 Postsurgical Pain COMPLETED NCT01582477
EXPAREL 20 mL Other Phase PHASE4 Postsurgical Pain COMPLETED NCT01582477
Placebo Other Phase PHASE4 Pain TERMINATED NCT01919190
EXPAREL Other Phase PHASE4 Pain TERMINATED NCT01919190
EXPAREL Other Phase PHASE1 Healthy Volunteers COMPLETED NCT02210247
Placebo Other Phase PHASE3 Posterolateral Thoracotomy COMPLETED NCT01802411
EXPAREL 266 mg Other Phase PHASE3 Posterolateral Thoracotomy COMPLETED NCT01802411
Bupivacaine Hydrochloride Other Phase PHASE3 Coronary Artery Disease COMPLETED NCT03270514
Exparel Injectable Product Other Phase PHASE3 Coronary Artery Disease COMPLETED NCT03270514
Placebo Other Phase PHASE4 Analgesia, Postoperative COMPLETED NCT03541941
Bupivacaine Hcl 0.25% Inj Other Phase PHASE4 Analgesia, Postoperative COMPLETED NCT03541941
Exparel Other Phase PHASE4 Analgesia, Postoperative COMPLETED NCT03541941
Bupivacaine HCl Other Phase PHASE4 Postoperative Pain Management TERMINATED NCT03015961
EXPAREL and bupivacaine HCl Other Phase PHASE4 Postoperative Pain Management TERMINATED NCT03015961
Bupivacaine Hydrochloride Other Phase PHASE4 Vaginal Hysterectomy TERMINATED NCT03907033
Liposomal bupivacaine Other Phase PHASE4 Vaginal Hysterectomy TERMINATED NCT03907033
Symptom Questionnaire Other Phase PHASE3 Malignant Neoplasms of Female Genital Organs TERMINATED NCT02740114
Pill Diary Other Phase PHASE3 Malignant Neoplasms of Female Genital Organs TERMINATED NCT02740114
Oxycodone Other Phase PHASE3 Malignant Neoplasms of Female Genital Organs TERMINATED NCT02740114
Liposomal Bupivacaine Other Phase PHASE3 Malignant Neoplasms of Female Genital Organs TERMINATED NCT02740114
Bupivacaine Other Phase PHASE3 Malignant Neoplasms of Female Genital Organs TERMINATED NCT02740114
Standard of Care Other Phase PHASE4 Postoperative Pain Management TERMINATED NCT03927911
EXPAREL and Bupivacaine Other Phase PHASE4 Postoperative Pain Management TERMINATED NCT03927911
Triamcinolone Acetonide Extended-Release Injectable Suspension Other Phase PHASE1 Osteoarthritis, Knee COMPLETED NCT04261049
Bupivacaine hydrochloride (HCl) Other Phase PHASE4 Pain, Postoperative COMPLETED NCT04278846
Depofoam bupivacaine Other Phase PHASE4 Pain, Postoperative COMPLETED NCT04278846
Bupivacaine Hydrochloride Other Phase PHASE3 Lower Extremity Surgery COMPLETED NCT04518462
Exparel Other Phase PHASE3 Lower Extremity Surgery COMPLETED NCT04518462
Exparel TAP + multi-modal pain regimen Other Phase PHASE4 Elective Cesarean Section COMPLETED NCT03853694
150 mcg Duramorph + multi-modal pain regimen Other Phase PHASE4 Elective Cesarean Section COMPLETED NCT03853694
50 mcg Duramorph+ EXPAREL + multi-modal pain regimen Other Phase PHASE4 Elective Cesarean Section COMPLETED NCT03853694
Normal Saline Other Phase PHASE1 Pain, Postoperative COMPLETED NCT04826328
FX301 Other Phase PHASE1 Pain, Postoperative COMPLETED NCT04826328
Cryoanalgesia (iovera°®) Other Approved Morton's Neuroma UNKNOWN NCT05604144
ioveraº sham Other Approved Post-Operative Pain Management TERMINATED NCT04191031
ioveraº Other Approved Post-Operative Pain Management TERMINATED NCT04191031
Sham cryoneurolysis procedure Procedure Approved Mastectomy COMPLETED NCT03578237
Cryoneurolysis (active) Other Approved Mastectomy COMPLETED NCT03578237
Exparel Other Phase PHASE1 Postoperative Pain Management COMPLETED NCT03485014
FX006 Other Phase PHASE2 Trochanteric Bursitis COMPLETED NCT04182672
Normal Saline Other Phase PHASE2 Osteoarthritis of the Shoulder TERMINATED NCT04160091
FX006 Other Phase PHASE2 Osteoarthritis of the Shoulder TERMINATED NCT04160091
FX006 32 mg Other Phase PHASE2 Osteoarthritis, Hip COMPLETED NCT04065074
Normal saline Other Phase PHASE3 Osteoarthritis, Hip TERMINATED NCT03793010
FX006 Other Phase PHASE3 Osteoarthritis, Hip TERMINATED NCT03793010
FX006 32 mg Other Phase PHASE3 Osteoarthritis, Knee COMPLETED NCT03529942
TAcs 40 mg Other Phase PHASE2 Osteoarthritis of the Shoulder COMPLETED NCT03382262
FX006 32 mg Other Phase PHASE2 Osteoarthritis of the Shoulder COMPLETED NCT03382262
TAcs 40 mg Other Phase PHASE2 Bilateral Knee Osteoarthritis COMPLETED NCT03378076
FX006 32 mg Other Phase PHASE2 Bilateral Knee Osteoarthritis COMPLETED NCT03378076
FX006 32 mg Other Phase PHASE3 Osteoarthritis of the Knee COMPLETED NCT03046446
TCA IR 40 mg Other Phase PHASE2 Osteoarthritis of the Knee COMPLETED NCT02762370
FX006 32 mg Other Phase PHASE2 Osteoarthritis of the Knee COMPLETED NCT02762370
TCA IR 40 Other Phase PHASE2 Osteoarthritis of the Knee COMPLETED NCT02637323
FX006 32 mg Other Phase PHASE2 Osteoarthritis of the Knee COMPLETED NCT02637323
TCA IR 40 mg Other Phase PHASE2 Post-traumatic Osteoarthritis of the Knee TERMINATED NCT02468583
FX006 32 mg Other Phase PHASE2 Post-traumatic Osteoarthritis of the Knee TERMINATED NCT02468583
TCA IR 40 Other Phase PHASE3 Osteoarthritis of the Knee COMPLETED NCT02357459
Placebo Other Phase PHASE3 Osteoarthritis of the Knee COMPLETED NCT02357459
FX006 Other Phase PHASE3 Osteoarthritis of the Knee COMPLETED NCT02357459
iovera° Sham Other Approved Arthritis of the Knee COMPLETED NCT02284113
iovera° Other Approved Arthritis of the Knee COMPLETED NCT02284113
Sham Comparator Other Approved Knee Osteoarthritis COMPLETED NCT02260921
iovera° Other Approved Knee Osteoarthritis COMPLETED NCT02260921
FX006 16 mg Other Phase PHASE2 Osteoarthritis of the Knee COMPLETED NCT02116972
Placebo Other Phase PHASE2 Osteoarthritis of the Knee COMPLETED NCT02116972
FX006 32 mg Other Phase PHASE2 Osteoarthritis of the Knee COMPLETED NCT02116972
TCA IR 40 mg Other Phase PHASE2 Osteoarthritis of the Knee COMPLETED NCT02003365
FX006 40 mg Other Phase PHASE2 Osteoarthritis of the Knee COMPLETED NCT02003365
FX006 10 mg Other Phase PHASE2 Osteoarthritis of the Knee COMPLETED NCT02003365
Treatment with Cryo-Touch III device Drug Approved Upper Limb Spasticity COMPLETED NCT01863901
Device: Cryo-Touch III Study treatment at Day 0. Drug Approved Occipital Neuralgia COMPLETED NCT01753765
Cryo-Touch III Other Approved Osteoarthritis of the Knee COMPLETED NCT01704157
Cryo-Touch III Other Approved Histological Response of Tissue to Cold COMPLETED NCT01681745
TCA IR 40 Other Phase PHASE2 Osteoarthritis of the Knee COMPLETED NCT01487200
FX006 60 mg Other Phase PHASE2 Osteoarthritis of the Knee COMPLETED NCT01487200
FX006 40 mg Other Phase PHASE2 Osteoarthritis of the Knee COMPLETED NCT01487200
FX006 10 mg Other Phase PHASE2 Osteoarthritis of the Knee COMPLETED NCT01487200
TCA IR Other Phase PHASE2 Osteoarthritis of the Knee COMPLETED NCT01487161
FX006 Other Phase PHASE2 Osteoarthritis of the Knee COMPLETED NCT01487161
Placebo 2 (Diluent) Other Phase PHASE1 Osteoarthritis, Knee COMPLETED NCT01291914
Placebo 1 (Carrier) Other Phase PHASE1 Osteoarthritis, Knee COMPLETED NCT01291914
FX005 Other Phase PHASE1 Osteoarthritis, Knee COMPLETED NCT01291914
Cryo-Touch II Other Phase PHASE2 Facial Wrinkles COMPLETED NCT01167140
Ropivacaine Other Phase PHASE4 Rotator Cuff Injury COMPLETED NCT03738696
Exparel Other Phase PHASE4 Rotator Cuff Injury COMPLETED NCT03738696
Liposomal bupivacaine (LB, Exparel) Other Phase PHASE4 Adolescent Idiopathic Scoliosis COMPLETED NCT05730920
Methadone Other Phase PHASE4 Adolescent Idiopathic Scoliosis COMPLETED NCT05730920
Bupivacaine Hydrochloride Other Phase PHASE3 Knee Osteoarthritis COMPLETED NCT05139030
bupivacaine liposome injectable suspension Other Phase PHASE3 Knee Osteoarthritis COMPLETED NCT05139030
Radiofrequency ablation Other Approved Low Back Pain COMPLETED NCT06016127
iovera system Other Approved Low Back Pain COMPLETED NCT06016127
Cryoneurolysis Other Approved ACL Repair RECRUITING NCT06603051
Bupivacain Other Phase PHASE2 Back Pain ENROLLING_BY_INVITATION NCT06350981
Exparel Other Phase PHASE2 Back Pain ENROLLING_BY_INVITATION NCT06350981
Acetaminophen 500Mg Cap Other Preclinical ACL Tear COMPLETED NCT06340932
Bupivacaine Hydrochloride Other Preclinical ACL Tear COMPLETED NCT06340932
Tramadol Other Preclinical ACL Tear COMPLETED NCT06340932
Oxycodone Other Preclinical ACL Tear COMPLETED NCT06340932
Acetaminophen Other Preclinical ACL Tear COMPLETED NCT06340932
Celecoxib Other Preclinical ACL Tear COMPLETED NCT06340932
Iovera Other Preclinical ACL Tear COMPLETED NCT06340932
Placebo Other Phase PHASE1 Healthy COMPLETED NCT05456490
Bupivacaine Other Phase PHASE1 Healthy COMPLETED NCT05456490
Liposomal Bupivacaine 13.3 Other Phase PHASE1 Healthy COMPLETED NCT05456490
FX201 Other Phase PHASE1 Osteoarthritis, Knee ACTIVE_NOT_RECRUITING NCT04119687
EXPAREL 1.3 % in 20 ML Injection Other Phase PHASE4 Rotator Cuff Tear TERMINATED NCT03290196
Radiofrequency ablation Other Approved Chronic Sacroiliac Joint Pain NOT_YET_RECRUITING NCT06935539
Cryoneurolysis Other Approved Chronic Sacroiliac Joint Pain NOT_YET_RECRUITING NCT06935539
Thoracic epidural analgesia (bupivacaine) Other Phase PHASE3 Surgery COMPLETED NCT04117074
Liposomal bupivacaine Other Phase PHASE3 Surgery COMPLETED NCT04117074
Bupivacaine liposome injectable suspension 133 mg Other Phase PHASE3 Bunionectomy COMPLETED NCT05157841
Bupivacaine HCl Other Phase PHASE3 Bunionectomy COMPLETED NCT05157841
Bupivacaine liposome injectable suspension 266 mg Other Phase PHASE3 Bunionectomy COMPLETED NCT05157841
Sham Cryoanalgesia Other Approved Postoperative Pain WITHDRAWN NCT06284109
Cryoanalgesia Other Approved Postoperative Pain WITHDRAWN NCT06284109
No cryoneurolysis Other Approved Degenerative Joint Disease of Shoulder RECRUITING NCT07125833
Cryoneurolysis Other Approved Degenerative Joint Disease of Shoulder RECRUITING NCT07125833
Local Infiltration Analgesia (LIA) of EXPAREL Other Approved Total Knee Arthroplasty RECRUITING NCT06946368
Adductor Canal Block (ACB) and Local Local Infiltration Analgesia of EXPAREL Other Approved Total Knee Arthroplasty RECRUITING NCT06946368
Intra-articular Posteromedial Surgeon Administered (IPSA) Block of EXPAREL Other Approved Total Knee Arthroplasty RECRUITING NCT06946368
an open surgery for abdominal hernia repair Procedure Phase PHASE4 Pain COMPLETED NCT02128646
laparoscopic abdominal hernia repair Other Phase PHASE4 Pain COMPLETED NCT02128646
Ketorolac Other Phase PHASE4 Pain COMPLETED NCT02128646
EXPAREL Other Phase PHASE4 Pain COMPLETED NCT02128646
Thoracic epidural analgesia Other Phase PHASE4 Laparotomy COMPLETED NCT03827291
Exparel Other Phase PHASE4 Laparotomy COMPLETED NCT03827291
Continuous popliteal nerve block with unencapsulated bupivacaine Other Phase PHASE4 Moderate-to-severely Painful Ankle Surgery ENROLLING_BY_INVITATION NCT06995352
Adductor canal nerve block with exclusively unencapsulated bupivacaine Other Phase PHASE4 Moderate-to-severely Painful Ankle Surgery ENROLLING_BY_INVITATION NCT06995352
Popliteal nerve block with exclusively unencapsulated bupivacaine Other Phase PHASE4 Moderate-to-severely Painful Ankle Surgery ENROLLING_BY_INVITATION NCT06995352
Continuous popliteal nerve block with normal saline Other Phase PHASE4 Moderate-to-severely Painful Ankle Surgery ENROLLING_BY_INVITATION NCT06995352
Adductor canal nerve block including liposomal bupivacaine Other Phase PHASE4 Moderate-to-severely Painful Ankle Surgery ENROLLING_BY_INVITATION NCT06995352
Popliteal nerve block including liposomal bupivacaine Other Phase PHASE4 Moderate-to-severely Painful Ankle Surgery ENROLLING_BY_INVITATION NCT06995352
Placebo Other Phase PHASE3 Glenohumeral Osteoarthritis RECRUITING NCT06269705
ZILRETTA Other Phase PHASE3 Glenohumeral Osteoarthritis RECRUITING NCT06269705
Triamcinolone Acetonide Other Phase PHASE2 Osteoarthritis of Hip TERMINATED NCT06977568
Zilretta Other Phase PHASE2 Osteoarthritis of Hip TERMINATED NCT06977568
bupivacaine Other Phase PHASE1 Postoperative Pain RECRUITING NCT06271265
EXPAREL Other Phase PHASE1 Postoperative Pain RECRUITING NCT06271265
Treatment for Knee OA Drug Preclinical Knee Osteoarthritis RECRUITING NCT05495334
Bupivacaine Hydrochloride Other Phase PHASE2 Pain, Postoperative ENROLLING_BY_INVITATION NCT06077422
bupivacaine liposome injectable suspension Other Phase PHASE2 Pain, Postoperative ENROLLING_BY_INVITATION NCT06077422
0.25% bupivacaine (HCl): 30 ml Other Phase PHASE3 Total Ankle Arthroplasty RECRUITING NCT07212114
0.25% bupivacaine (HCl): 50 ml Other Phase PHASE3 Total Ankle Arthroplasty RECRUITING NCT07212114
EXPAREL Other Phase PHASE3 Total Ankle Arthroplasty RECRUITING NCT07212114
ioveraº system Other Preclinical Pain Management Improvement COMPLETED NCT06093776
Placebo Other Phase PHASE2 Osteoarthritis (OA) of the Knee ACTIVE_NOT_RECRUITING NCT06884865
Enekinragene Inzadenovec (PCRX-201) Other Phase PHASE2 Osteoarthritis (OA) of the Knee ACTIVE_NOT_RECRUITING NCT06884865
sham iovera° system treatment Drug Approved Spasticity, Cerebral or Spinal Condition RECRUITING NCT06340451
iovera° system Other Approved Spasticity, Cerebral or Spinal Condition RECRUITING NCT06340451
Best Practices Other Phase PHASE3 Knee Osteoarthritis COMPLETED NCT04504812
Pain Coping Skills Training Other Phase PHASE3 Knee Osteoarthritis COMPLETED NCT04504812
Nerve Procedure with nerve ablation Procedure Phase PHASE3 Knee Osteoarthritis COMPLETED NCT04504812
Nerve Procedure with long acting blocks Procedure Phase PHASE3 Knee Osteoarthritis COMPLETED NCT04504812
Intra-Articular Injection Other Phase PHASE3 Knee Osteoarthritis COMPLETED NCT04504812
Duloxetine Other Phase PHASE3 Knee Osteoarthritis COMPLETED NCT04504812
Cryoneurolysis Other Approved Spasticity as Sequela of Stroke RECRUITING NCT06958289
Radiofrequency ablation (RFA) Other Approved Low Back Pain, Chronic RECRUITING NCT07214844
Iovera Medial Branch Cryoneurolysis Other Approved Low Back Pain, Chronic RECRUITING NCT07214844
Radiofrequency ablation (RFA) Other Approved Low Back Pain, Chronic RECRUITING NCT07214844
Iovera Medial Branch Cryoneurolysis Other Approved Low Back Pain, Chronic RECRUITING NCT07214844
Radiofrequency ablation (RFA) Other Approved Low Back Pain, Chronic RECRUITING NCT07214844
Iovera Medial Branch Cryoneurolysis Other Approved Low Back Pain, Chronic RECRUITING NCT07214844
Radiofrequency ablation (RFA) Other Approved Low Back Pain, Chronic RECRUITING NCT07214844
Iovera Medial Branch Cryoneurolysis Other Approved Low Back Pain, Chronic RECRUITING NCT07214844
Radiofrequency ablation (RFA) Other Approved Low Back Pain, Chronic RECRUITING NCT07214844
Iovera Medial Branch Cryoneurolysis Other Approved Low Back Pain, Chronic RECRUITING NCT07214844
Radiofrequency ablation (RFA) Other Approved Low Back Pain, Chronic RECRUITING NCT07214844
Iovera Medial Branch Cryoneurolysis Other Approved Low Back Pain, Chronic RECRUITING NCT07214844
Radiofrequency ablation (RFA) Other Approved Low Back Pain, Chronic RECRUITING NCT07214844
Iovera Medial Branch Cryoneurolysis Other Approved Low Back Pain, Chronic RECRUITING NCT07214844
Radiofrequency ablation (RFA) Other Approved Low Back Pain, Chronic RECRUITING NCT07214844
Iovera Medial Branch Cryoneurolysis Other Approved Low Back Pain, Chronic RECRUITING NCT07214844
Radiofrequency ablation (RFA) Other Approved Low Back Pain, Chronic RECRUITING NCT07214844
Iovera Medial Branch Cryoneurolysis Other Approved Low Back Pain, Chronic RECRUITING NCT07214844
Radiofrequency ablation (RFA) Other Approved Low Back Pain, Chronic RECRUITING NCT07214844
Iovera Medial Branch Cryoneurolysis Other Approved Low Back Pain, Chronic RECRUITING NCT07214844
Radiofrequency ablation (RFA) Other Approved Low Back Pain, Chronic RECRUITING NCT07214844
Iovera Medial Branch Cryoneurolysis Other Approved Low Back Pain, Chronic RECRUITING NCT07214844
Cryoneurolysis Other Approved Spasticity as Sequela of Stroke RECRUITING NCT06958289
Cryoneurolysis Other Approved Spasticity as Sequela of Stroke RECRUITING NCT06958289
Cryoneurolysis Other Approved Spasticity as Sequela of Stroke RECRUITING NCT06958289
Cryoneurolysis Other Approved Spasticity as Sequela of Stroke RECRUITING NCT06958289
Cryoneurolysis Other Approved Spasticity as Sequela of Stroke RECRUITING NCT06958289
Cryoneurolysis Other Approved Spasticity as Sequela of Stroke RECRUITING NCT06958289
Total products: 354