| Symbol | PCRX |
|---|---|
| Name | PACIRA BIOSCIENCES, INC. |
| Sector | HEALTH CARE |
| Region | North America |
| Industry | Biotechnology: Pharmaceutical Preparations |
| Address | 5401 WEST KENNEDY BOULEVARD,SUITE 890, TAMPA, Florida, 33609, United States |
| Telephone | +1 813 553-6680 |
| Fax | — |
| — | |
| Website | https://www.pacira.com |
| Incorporation | UNDEFINED |
| Incorporated On | — |
| Employees | — |
| Fiscal Year | — |
| Public Since | — |
| Exchanges | NASDAQ |
| Auditor | — |
| Audit Status | NOT PROVIDED |
| Reporting Status | — |
| CIK | 0001396814 |
| Description | Pacira BioSciences Inc is a provider of non-opioid pain management and regenerative health solutions dedicated to advancing and improving outcomes for health care practitioners and their patients. The company has launched EXPAREL which utilizes DepoFoam, a product delivery technology that encapsulates drugs without altering their molecular structure, and releases them over a desired period of time. Additional info from NASDAQ: |
Director Hirawat Samit 🟢 acquired 17.3K shares (1 derivative) of Pacira BioSciences, Inc. (PCRX) at $23.42 Transaction Date: Jun 10, 2026 | Filing ID: 043010
Read moreRIKER LAUREN 🔴 sold 6.1K shares of Pacira BioSciences, Inc. (PCRX) at $23.50 Transaction Date: Jun 11, 2026 | Filing ID: 043009
Read moreDirector CHRISTIE CHRISTOPHER 🟢 acquired 17.3K shares (1 derivative) of Pacira BioSciences, Inc. (PCRX) at $23.42 Transaction Date: Jun 10, 2026 | Filing ID: 043008
Read moreDirector WIGGANS THOMAS G 🟢 acquired 32.7K shares (1 derivative) of Pacira BioSciences, Inc. (PCRX) at $23.42 Transaction Date: Jun 10, 2026 | Filing ID: 043007
Read moreDirector Young Alethia 🟢 acquired 17.3K shares (1 derivative) of Pacira BioSciences, Inc. (PCRX) at $23.42 Transaction Date: Jun 10, 2026 | Filing ID: 043006
Read moreDirector YANG MICHAEL J. 🟢 acquired 17.3K shares (1 derivative) of Pacira BioSciences, Inc. (PCRX) at $23.42 Transaction Date: Jun 10, 2026 | Filing ID: 043005
Read moreDirector BIGAL MARCELO 🟢 acquired 17.3K shares (1 derivative) of Pacira BioSciences, Inc. (PCRX) at $23.42 Transaction Date: Jun 10, 2026 | Filing ID: 043004
Read moreDirector Froimson Mark 🟢 acquired 17.3K shares (1 derivative) of Pacira BioSciences, Inc. (PCRX) at $23.42 Transaction Date: Jun 10, 2026 | Filing ID: 043003
Read moreDirector Brege Laura 🟢 acquired 17.3K shares (1 derivative) of Pacira BioSciences, Inc. (PCRX) at $23.42 Transaction Date: Jun 10, 2026 | Filing ID: 043002
Read moreNew Form 3 - Pacira BioSciences, Inc. <b>Filed:</b> 2026-06-12 <b>AccNo:</b> 0001628280-26-043001 <b>Size:</b> 9 KB
Read more| Trial ID | Title | Phase | Indication | Status | Start Date | Completion Date | Source |
|---|---|---|---|---|---|---|---|
| NCT07584915 | Pilot Study on EXPAREL as an Intra-articular Posteromedial Surgeon Administered… | Phase4 | Total Knee Arthroplasty | Enrolling_By_Invitation | 2026-06-01 | 2026-08-01 | ClinicalTrials.gov |
| NCT07214844 | A Prospective Study to Evaluate the Efficacy of Iovera Lumbar Medial Branch Cry… | Na | Low Back Pain, Chronic | Recruiting | 2026-04-16 | 2028-05-01 | ClinicalTrials.gov |
| NCT07212114 | Efficacy of EXPAREL vs. Bupivacaine | Phase3 | Total Ankle Arthroplasty | Recruiting | 2025-11-17 | 2029-08-01 | ClinicalTrials.gov |
| NCT06946368 | Effectiveness of Exparel Anesthetic Administered by the Surgeon During Knee Sur… | Na | Total Knee Arthroplasty | Recruiting | 2025-08-18 | 2026-12-11 | ClinicalTrials.gov |
| NCT06958289 | Cryoneurolysis for Spasticity Treatment: Long-term Clinical Outcomes and Mechan… | Na | Spasticity as Sequela of Stroke | Recruiting | 2025-08-01 | 2028-05-01 | ClinicalTrials.gov |
| NCT07125833 | Cryoneurolysis of the Suprascapular Nerve for Perioperative Pain Control After … | Na | Degenerative Joint Disease of Shoulder | Recruiting | 2025-07-30 | 2026-08-01 | ClinicalTrials.gov |
| NCT06977568 | A Study to Evaluate an Intra-Articular Injection of ZILRETTA Versus Triamcinolo… | Phase2 | Osteoarthritis of Hip | Terminated | 2025-07-25 | 2025-10-16 | ClinicalTrials.gov |
| NCT06995352 | Liposomal Bupivacaine Versus Continuous Peripheral Nerve Blocks for Analgesia F… | Phase4 | Moderate-to-severely Painful Ankle Surgery | Enrolling_By_Invitation | 2025-06-23 | 2027-06-22 | ClinicalTrials.gov |
| NCT06935539 | Cryoneurolysis vs Radiofrequency Ablation for Chronic Sacroiliac Joint Pain | Na | Chronic Sacroiliac Joint Pain | Not_Yet_Recruiting | 2025-05-01 | 2026-08-01 | ClinicalTrials.gov |
| NCT06884865 | A Study to Assess Safety and Tolerability of PCRX-201 in Subjects With Painful … | Phase2 | Osteoarthritis (OA) of the Knee | Active_Not_Recruiting | 2025-02-26 | 2032-07-01 | ClinicalTrials.gov |
| NCT06603051 | The Effect of Pre-Operative Cryoneurolysis on Post-Operative Narcotic Consumpti… | Na | ACL Repair | Recruiting | 2024-08-28 | 2027-10-01 | ClinicalTrials.gov |
| NCT06340451 | Study to Assess the Efficacy and Safety of Iovera®° System in Subjects With Upp… | Na | Spasticity, Cerebral or Spinal Condition | Recruiting | 2024-07-11 | 2026-08-01 | ClinicalTrials.gov |
| NCT06284109 | Preoperative (Pre-amputation) Cryoanalgesia to Improve Post-amputation Phantom … | Na | Postoperative Pain | Withdrawn | 2024-06-01 | 2024-09-10 | ClinicalTrials.gov |
| NCT06350981 | Analgesic Requirement for Post-Operative Pain Control in TLIP Interbody Fusion | Phase2 | Back Pain | Enrolling_By_Invitation | 2024-04-30 | 2026-03-01 | ClinicalTrials.gov |
| NCT06340932 | Impact of Opioid Avoidance Protocol for ACL Reconstruction | — | ACL Tear | Completed | 2024-04-27 | 2025-02-01 | ClinicalTrials.gov |
| NCT06271265 | Study to Evaluate the Pharmacokinetics and Safety of EXPAREL for Postoperative … | Phase1 | Postoperative Pain | Recruiting | 2024-03-29 | 2027-01-01 | ClinicalTrials.gov |
| NCT06269705 | ZILRETTA in Subjects With Shoulder Osteoarthritis | Phase3 | Glenohumeral Osteoarthritis | Active_Not_Recruiting | 2024-02-05 | 2026-12-01 | ClinicalTrials.gov |
| NCT06077422 | Exparel vs. Marcaine ESP Block for Post-cardiac Surgical Pain | Phase2 | Pain, Postoperative | Enrolling_By_Invitation | 2024-01-11 | 2027-04-05 | ClinicalTrials.gov |
| NCT06093776 | Rib Fracture Cryoanalgesia | — | Pain Management Improvement | Completed | 2023-06-05 | 2025-06-12 | ClinicalTrials.gov |
| NCT05456490 | Phase 1, Dose Escalation Study to Evaluate of Safety, Pharmacokinetics and Phar… | Phase1 | Healthy | Completed | 2023-04-18 | 2025-02-27 | ClinicalTrials.gov |
| NCT05730920 | IV Methadone Vs EXPAREL Erector Spinae Plane Blockade in Pediatric Subjects Und… | Phase4 | Adolescent Idiopathic Scoliosis | Completed | 2022-10-19 | 2024-09-21 | ClinicalTrials.gov |
| NCT05604144 | Cryoanalgesia for the Treatment of Pain in Subjects With Morton's Neuroma | Na | Morton's Neuroma | Unknown | 2022-08-22 | 2023-04-22 | ClinicalTrials.gov |
| NCT06016127 | Cryoneurolysis for Facet Mediated Chronic Low Back Pain | Na | Low Back Pain | Completed | 2022-06-18 | 2023-10-23 | ClinicalTrials.gov |
| NCT05157841 | Phase 3, Sciatic Nerve Block With EXPAREL for Subjects Undergoing Bunionectomy | Phase3 | Bunionectomy | Completed | 2022-02-15 | 2022-08-17 | ClinicalTrials.gov |
| NCT05139030 | Phase 3 Adductor Canal Block With EXPAREL in Subjects Undergoing Primary Unilat… | Phase3 | Knee Osteoarthritis | Completed | 2022-01-18 | 2022-07-11 | ClinicalTrials.gov |
| NCT05495334 | Innovations in Genicular Outcomes Registry | — | Knee Osteoarthritis | Recruiting | 2021-09-23 | 2033-12-30 | ClinicalTrials.gov |
| NCT04117074 | Thoracic Epidural Analgesia vs Surgical Site Infiltration With Liposomal Bupiva… | Phase3 | Surgery | Completed | 2021-04-14 | 2025-03-17 | ClinicalTrials.gov |
| NCT04826328 | Study to Evaluate the Safety and Tolerability of FX301 in Patients Undergoing B… | Phase1 | Pain, Postoperative | Completed | 2021-03-15 | 2022-03-30 | ClinicalTrials.gov |
| NCT04504812 | A Sequenced Strategy for Improving Outcomes in People With Knee Osteoarthritis … | Phase3 | Knee Osteoarthritis | Completed | 2021-02-01 | 2025-04-08 | ClinicalTrials.gov |
| NCT04518462 | Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of EXPAREL, EXPARE… | Phase3 | Lower Extremity Surgery | Completed | 2020-10-20 | 2021-04-05 | ClinicalTrials.gov |
| NCT04191031 | Study to Evaluate Iovera®° in Adult Patients Undergoing Total Knee Arthroplasty | Na | Post-Operative Pain Management | Terminated | 2020-09-30 | 2022-07-12 | ClinicalTrials.gov |
| NCT04182672 | Study to Assess the Safety and Efficacy of FX006 Administered to Patients With … | Phase2 | Trochanteric Bursitis | Completed | 2020-08-12 | 2022-12-14 | ClinicalTrials.gov |
| NCT04261049 | Effect of Zilretta Injection | Phase1 | Osteoarthritis, Knee | Completed | 2020-08-01 | 2022-01-10 | ClinicalTrials.gov |
| NCT03954639 | Phase 3, Randomized, Double Blinded, Active Controlled, Multicenter Study to Ev… | Phase3 | Bunion | Withdrawn | 2020-06-15 | 2020-09-01 | ClinicalTrials.gov |
| NCT04173611 | Evaluation of Safety, Pharmacokinetics and Pharmacodynamics of EXPAREL® Adminis… | Phase1 | Healthy | Terminated | 2020-06-08 | 2020-12-07 | ClinicalTrials.gov |
| NCT04119687 | Study to Evaluate the Safety and Tolerability of FX201 in Patients with Osteoar… | Phase1 | Osteoarthritis, Knee | Active_Not_Recruiting | 2020-03-02 | 2026-11-28 | ClinicalTrials.gov |
| NCT04293809 | Study to Evaluate the Pharmacokinetics and Safety of EXPAREL Administered as a … | Phase1 | Breast Augmentation | Completed | 2019-12-19 | 2020-01-29 | ClinicalTrials.gov |
| NCT03738696 | Liposomal Bupivacaine in Rotator Cuff Repair | Phase4 | Rotator Cuff Injury | Completed | 2019-12-15 | 2022-01-01 | ClinicalTrials.gov |
| NCT04160091 | Study to Evaluate the Efficacy and Safety of FX006 in Patients With Glenohumera… | Phase2 | Osteoarthritis of the Shoulder | Terminated | 2019-11-07 | 2020-06-15 | ClinicalTrials.gov |
| NCT03739021 | Exparel for Total Shoulder Pain | Phase2 | Chronic Shoulder Pain | Not_Yet_Recruiting | 2019-11-01 | 2020-11-15 | ClinicalTrials.gov |
| NCT03827291 | QL Block With Exparel in Colectomy | Phase4 | Laparotomy | Completed | 2019-10-31 | 2022-12-09 | ClinicalTrials.gov |
| NCT03907033 | Liposomal Bupivacaine in Vaginal Hysterectomy | Phase4 | Vaginal Hysterectomy | Terminated | 2019-09-03 | 2021-07-23 | ClinicalTrials.gov |
| NCT03955458 | EXPAREL Facia Iliaca Compartment Block for Intertrochanteric Hip Fracture | Phase4 | Hip Fractures | Withdrawn | 2019-08-26 | 2020-05-01 | ClinicalTrials.gov |
| NCT03975283 | Use of Exparel for Postoperative Analgesia Following Bariatric Surgery | Phase4 | Post Operative Pain | Unknown | 2019-08-01 | 2021-08-01 | ClinicalTrials.gov |
| NCT03927911 | Phase 4 Study in Adult Subjects Undergoing Posterior Lumbar Spine Surgeries | Phase4 | Postoperative Pain Management | Terminated | 2019-07-31 | 2020-08-04 | ClinicalTrials.gov |
| NCT04065074 | Study to Evaluate a Procedure for Intra-articular Injection of FX006 in Patient… | Phase2 | Osteoarthritis, Hip | Completed | 2019-07-30 | 2019-12-30 | ClinicalTrials.gov |
| NCT04002089 | Study to Evaluate the Pharmacokinetics, Pharmacodynamics and Safety, of EXPAREL… | Phase1 | Bunion | Completed | 2019-07-26 | 2019-12-02 | ClinicalTrials.gov |
| NCT03909516 | Evaluate the Iovera° Device in Treating Pain Associated With Anterior Cruciate … | Na | ACL Reconstruction | Withdrawn | 2019-05-01 | 2019-05-01 | ClinicalTrials.gov |
| NCT03682302 | Multicenter Study for Pediatric Subjects Evaluating Pharmacokinetics and Safety… | Phase3 | Postoperative Pain Management | Completed | 2019-04-02 | 2019-09-24 | ClinicalTrials.gov |
| NCT03853694 | Efficacy and Safety of EXPAREL Versus Standard of Care (SoC) in Subjects Underg… | Phase4 | Elective Cesarean Section | Completed | 2019-03-04 | 2020-01-16 | ClinicalTrials.gov |
| NCT03836313 | Assessing if Cryoneurolysis Improves Prehabilitation and Decreases Pain After S… | Na | Arthropathy of Knee | Withdrawn | 2019-03-01 | 2021-06-01 | ClinicalTrials.gov |
| NCT03802864 | Post-operative Pain Control of Testicular Sperm Extraction Using Liposomal Bupi… | Phase4 | Male Infertility | Completed | 2019-02-04 | 2020-01-30 | ClinicalTrials.gov |
| NCT03793010 | Study to Evaluate the Efficacy and Safety of FX006 in Patients With Hip Osteoar… | Phase3 | Osteoarthritis, Hip | Terminated | 2018-12-12 | 2019-08-07 | ClinicalTrials.gov |
| NCT03270514 | Comparison of Sternal Wound Infiltration With Liposomal Bupivacaine v. Bupivaca… | Phase3 | Coronary Artery Disease | Completed | 2018-11-15 | 2020-02-25 | ClinicalTrials.gov |
| NCT03688477 | Iovera° to Treat Pain Associated With ACL Reconstruction and Rehabilitation | Na | Anterior Cruciate Ligament Reconstruction | Withdrawn | 2018-10-01 | 2019-06-01 | ClinicalTrials.gov |
| NCT03578237 | Cryoanalgesia to Prevent Acute and Chronic Pain Following Surgery: A Randomized… | Na | Mastectomy | Completed | 2018-08-25 | 2022-11-25 | ClinicalTrials.gov |
| NCT03541941 | Exparel vs. Bupivacaine Hydrochloride vs. Placebo for Hernia Repair | Phase4 | Analgesia, Postoperative | Completed | 2018-07-03 | 2019-12-19 | ClinicalTrials.gov |
| NCT03428984 | Study in Adult Subjects Undergoing Posterolateral Thoracotomy | Phase1 | Postoperative Pain Management | Terminated | 2018-05-03 | 2018-09-28 | ClinicalTrials.gov |
| NCT03529942 | Study to Evaluate the Effect of FX006 on Synovial Inflammation in Patients With… | Phase3 | Osteoarthritis, Knee | Completed | 2018-04-24 | 2020-03-09 | ClinicalTrials.gov |
| NCT03485014 | Study in Pediatric Subjects Evaluating Pharmacokinetics and Safety of EXPAREL | Phase1 | Postoperative Pain Management | Completed | 2018-04-10 | 2019-02-12 | ClinicalTrials.gov |
| NCT03382262 | Study to Compare Exposure of TA Following Administration of FX006 or TAcs in Pa… | Phase2 | Osteoarthritis of the Shoulder | Completed | 2017-12-18 | 2018-10-09 | ClinicalTrials.gov |
| NCT03378076 | Study to Compare Exposure of TA Following Administration of Either FX006 or TAc… | Phase2 | Bilateral Knee Osteoarthritis | Completed | 2017-12-06 | 2018-03-14 | ClinicalTrials.gov |
| NCT03149887 | Liposomal Bupivacaine After Arthroscopic Rotator Cuff Repair | Phase4 | Rotator Cuff Tear | Completed | 2017-12-05 | 2019-03-01 | ClinicalTrials.gov |
| NCT03327220 | Treatment With Iovera° for Total Knee Arthroplasty (TKA) Post-Operative Pain | Na | Total Knee Arthroplasty | Completed | 2017-11-06 | 2019-03-27 | ClinicalTrials.gov |
| NCT03076710 | Post-Operative Pain Management Following Spine Surgery | — | Pain Management | Withdrawn | 2017-07-31 | 2022-03-01 | ClinicalTrials.gov |
| NCT03176459 | Evaluate the Safety and Efficacy of EXPAREL When Administered Via Infiltration … | Phase4 | C-Section | Completed | 2017-06-01 | 2018-12-04 | ClinicalTrials.gov |
| NCT03015961 | Phase 4, Controlled Study in Adult Subjects Undergoing Primary, 1-2 Level, Open… | Phase4 | Postoperative Pain Management | Terminated | 2017-02-21 | 2017-10-30 | ClinicalTrials.gov |
| NCT03046446 | Study to Assess the Safety of Repeat Administration of FX006 Administered to Pa… | Phase3 | Osteoarthritis of the Knee | Completed | 2017-02-20 | 2018-07-19 | ClinicalTrials.gov |
| NCT03106519 | Liposome Bupivacaine for WRIST Blocks | Phase2 | Dupuytren's Contracture of the Hand (Viking's Disease) | Completed | 2017-01-02 | 2017-10-31 | ClinicalTrials.gov |
| NCT03106545 | Liposome Bupivacaine for ANKLE Blocks | Phase2 | Hallux Valgus (Bunions) | Completed | 2017-01-02 | 2017-10-31 | ClinicalTrials.gov |
| NCT02985762 | PK Study of EXPAREL in Subjects Undergoing Open Spinal Fusion or Reconstructive… | Phase1 | Spinal Fusion | Completed | 2016-12-01 | 2017-09-01 | ClinicalTrials.gov |
| NCT02922582 | Study of Local Administration of DepoTXA for Reduced Postsurgical Bleeding in S… | Phase2 | Total Knee Arthroplasty | Terminated | 2016-10-28 | 2017-11-27 | ClinicalTrials.gov |
| NCT02821325 | Intra-articular Volumetric Assessment After Total Knee Arthroplasty | — | Hematoma | Completed | 2016-09-28 | 2018-01-30 | ClinicalTrials.gov |
| NCT02740114 | Wound Infiltration With Liposomal Bupivacaine vs. Standard Wound Infiltration W… | Phase3 | Malignant Neoplasms of Female Genital Organs | Terminated | 2016-08-31 | 2020-07-23 | ClinicalTrials.gov |
| NCT02713178 | Efficacy, Safety, and Pharmacokinetics of Femoral Nerve Block With EXPAREL in T… | Phase3 | Pain | Completed | 2016-06-03 | 2017-06-30 | ClinicalTrials.gov |
| NCT02713230 | Efficacy, Safety, and Pharmacokinetics of Brachial Plexus Block With EXPAREL in… | Phase3 | Pain | Completed | 2016-05-09 | 2017-07-07 | ClinicalTrials.gov |
| NCT02713490 | Local Infiltration Analgesia With and Without EXPAREL Following Total Knee Arth… | Phase4 | Pain | Completed | 2016-04-18 | 2017-02-08 | ClinicalTrials.gov |
| NCT02762370 | Study to Assess the Effects of FX006 on Blood Glucose in Patients With OA of th… | Phase2 | Osteoarthritis of the Knee | Completed | 2016-04-01 | 2016-11-01 | ClinicalTrials.gov |
| NCT02637323 | Study to Characterize the PK and Local Extent and Duration of Exposure From FX0… | Phase2 | Osteoarthritis of the Knee | Completed | 2015-11-01 | 2016-09-01 | ClinicalTrials.gov |
| NCT03290196 | The Effect of EXPAREL® on Postsurgical Pain, and the Use of Narcotics | Phase4 | Rotator Cuff Tear | Terminated | 2015-09-03 | 2022-04-07 | ClinicalTrials.gov |
| NCT02517905 | Evaluation of EXPAREL for Prolonged Postsurgical Analgesia in Subjects Undergoi… | Phase3 | Dental Pain | Completed | 2015-08-01 | 2016-01-01 | ClinicalTrials.gov |
| NCT02554357 | Quality of Analgesia After Interscalene Block After Arthroscopic Shoulder Surge… | Na | Injury of Shoulder Region | Completed | 2015-07-01 | 2016-03-01 | ClinicalTrials.gov |
| NCT02353754 | Evaluation of the Safety and Efficacy of EXPAREL When Administered Into the TAP… | Phase4 | Pain | Terminated | 2015-05-01 | 2015-07-01 | ClinicalTrials.gov |
| NCT02468583 | Proof of Concept Study Comparing FX006 to Kenalog®-40 in Patients With Post-Tra… | Phase2 | Post-traumatic Osteoarthritis of the Knee | Terminated | 2015-02-01 | 2016-07-01 | ClinicalTrials.gov |
| NCT02357459 | Study of FX006 for the Treatment of Pain in Patients With Osteoarthritis of the… | Phase3 | Osteoarthritis of the Knee | Completed | 2015-01-01 | 2016-01-01 | ClinicalTrials.gov |
| NCT02284113 | A Randomized, Study to Evaluate the Iovera° Device in Treating Pain Associated … | Na | Arthritis of the Knee | Completed | 2014-12-01 | 2016-06-01 | ClinicalTrials.gov |
| NCT02284386 | Pharmacokinetics and Safety of Bupivacaine HCl Spinal Block and EXPAREL Local I… | Phase4 | Pain | Completed | 2014-12-01 | 2015-03-01 | ClinicalTrials.gov |
| NCT02260921 | Study to Evaluate the Iovera° Device for Temporary Relief From Knee Pain | Na | Knee Osteoarthritis | Completed | 2014-10-20 | 2016-05-31 | ClinicalTrials.gov |
| NCT02255500 | EXPAREL Infiltration in Subjects Undergoing Femoral Nerve Block With Bupivacain… | Phase4 | Pain | Completed | 2014-09-01 | 2015-03-01 | ClinicalTrials.gov |
| NCT04278846 | Efficacy of Liposomal Bupivacaine for Prolonged Postoperative Analgesia in Pati… | Phase4 | Pain, Postoperative | Completed | 2014-08-22 | 2019-05-15 | ClinicalTrials.gov |
| NCT02787226 | Liposomal Bupivacaine Infiltration vs Continuous Perineural Ropivacaine Infusio… | Phase4 | Postoperative Pain | Terminated | 2014-08-01 | 2017-05-31 | ClinicalTrials.gov |
| NCT02210247 | Safety and Pharmacokinetics Study of Redosing EXPAREL in Healthy Volunteers | Phase1 | Healthy Volunteers | Completed | 2014-08-01 | 2014-09-01 | ClinicalTrials.gov |
| NCT02199574 | Pharmacokinetic Evaluation of EXPAREL in Adults Undergoing Tonsillectomy | Phase4 | Pain | Completed | 2014-08-01 | 2015-06-01 | ClinicalTrials.gov |
| NCT02128646 | Liposomal Bupivacaine (Exparel) for Postoperative Pain Control for Open and Lap… | Phase4 | Pain | Completed | 2014-04-01 | 2017-01-01 | ClinicalTrials.gov |
| NCT02116972 | Study of FX006 vs Normal Saline in Patients With Osteoarthritis of the Knee | Phase2 | Osteoarthritis of the Knee | Completed | 2014-04-01 | 2015-11-01 | ClinicalTrials.gov |
| NCT02058303 | Study of A Long Lasting Local Anesthestic for Hand, Wrist or Finger Surgery | Phase4 | Hand Injuries | Terminated | 2014-02-01 | 2016-03-01 | ClinicalTrials.gov |
| NCT02586077 | Foot and Ankle Clinic Application for Liposomal Related Anesthetic | Phase4 | Ankle Arthrodesis | Completed | 2014-02-01 | 2016-11-15 | ClinicalTrials.gov |
| NCT02003365 | Study to Characterize the Local Duration of Exposure From FX006 in Patients Wit… | Phase2 | Osteoarthritis of the Knee | Completed | 2013-11-01 | 2014-04-01 | ClinicalTrials.gov |
| NCT01950065 | Effectiveness and Safety Study of the Iovera Device for the Temporary Reduction… | Na | Forehead Wrinkles | Completed | 2013-09-01 | 2014-10-01 | ClinicalTrials.gov |
| NCT01984619 | Prospective Study Evaluating the Treatment of Hyperdynamic Forehead Wrinkles | — | Wrinkles | Completed | 2013-09-01 | 2014-09-01 | ClinicalTrials.gov |
| NCT01919190 | EXPAREL Administered by Infiltration Into the TAP for Prolonged Postsurgical An… | Phase4 | Pain | Terminated | 2013-08-01 | 2014-02-01 | ClinicalTrials.gov |
| NCT01863901 | Study Evaluating Treatment of Upper Limb Spasticity Using the Cryo-Touch III De… | Na | Upper Limb Spasticity | Completed | 2013-04-01 | 2013-10-01 | ClinicalTrials.gov |
| NCT01801826 | A Prospective Study Evaluating the Treatment of Forehead and/or Glabellar Lines… | — | Frown Lines | Completed | 2013-01-01 | 2014-12-01 | ClinicalTrials.gov |
| NCT01802411 | Intercostal Nerve Block With Liposome Bupivacaine in Subjects Undergoing Poster… | Phase3 | Posterolateral Thoracotomy | Completed | 2012-12-01 | 2013-06-01 | ClinicalTrials.gov |
| NCT02142829 | Pain Control in Bariatric Patients: EXPAREL(R) vs. the On-Q(R) Pain Ball | Phase4 | Obesity | Completed | 2012-11-01 | 2013-03-01 | ClinicalTrials.gov |
| NCT01753778 | Study Evaluating Treatment of Forefoot Pain Related to Nerve Entrapment Using t… | Na | Entrapment Neuropathy | Completed | 2012-11-01 | 2013-08-01 | ClinicalTrials.gov |
| NCT01808742 | Study Evaluating the Treatment of Forehead and/or Glabellar Lines With the CRYO… | — | Frown Lines | Completed | 2012-11-01 | 2014-08-01 | ClinicalTrials.gov |
| NCT01753765 | Study Evaluating the Treatment of Occipital Neuralgia | Na | Occipital Neuralgia | Completed | 2012-10-01 | 2014-07-01 | ClinicalTrials.gov |
| NCT01704157 | A Prospective Study Evaluating the Treatment of Knee Osteoarthritis With the Cr… | Na | Osteoarthritis of the Knee | Completed | 2012-09-01 | 2013-07-01 | ClinicalTrials.gov |
| NCT01683071 | Femoral Nerve Block With Liposome Bupivacaine for Postsurgical Analgesia Follow… | Phase2 | Postoperative Pain | Completed | 2012-09-01 | 2013-12-01 | ClinicalTrials.gov |
| NCT01919606 | EXPAREL Administered Into the TAP for Analgesia in Subjects Undergoing Open Tot… | Phase4 | Postoperative Pain | Terminated | 2012-08-01 | 2012-10-01 | ClinicalTrials.gov |
| NCT01487200 | Pharmacokinetic and Pharmacodynamic Study of FX006 in Patients With Osteoarthri… | Phase2 | Osteoarthritis of the Knee | Completed | 2012-07-01 | 2012-11-01 | ClinicalTrials.gov |
| NCT01487161 | Study of FX006 in Patients With Osteoarthritis of the Knee | Phase2 | Osteoarthritis of the Knee | Completed | 2012-06-01 | 2013-04-01 | ClinicalTrials.gov |
| NCT01681745 | Probe Configuration and Time-Temperature Dose Ranging for Understanding of Skin… | Na | Histological Response of Tissue to Cold | Completed | 2012-06-01 | 2015-04-01 | ClinicalTrials.gov |
| NCT01507233 | A Health Economic Trial in Adult Patients Undergoing Open Colectomy MA402S23B302 | Phase4 | Bowel Obstruction | Terminated | 2012-05-01 | 2012-07-01 | ClinicalTrials.gov |
| NCT01801124 | EXPAREL Infiltrated Into the TAP for Postoperative Analgesia in Unilateral Abdo… | Phase4 | Hernia | Completed | 2012-04-01 | 2012-12-01 | ClinicalTrials.gov |
| NCT01582490 | Study of EXPAREL in Patients Undergoing Breast Augmentation | Phase4 | Mammoplasty | Completed | 2012-04-01 | 2012-11-01 | ClinicalTrials.gov |
| NCT01509638 | A Health Economic Trial in Adult Patients Undergoing Ileostomy Reversal MA402S2… | Phase4 | Retraction of Colostomy | Completed | 2012-03-01 | 2012-10-01 | ClinicalTrials.gov |
| NCT01582477 | TAP-patients With Robotic Assisted Lap Prostatectomy | Phase4 | Postsurgical Pain | Completed | 2012-03-01 | 2012-07-01 | ClinicalTrials.gov |
| NCT01507220 | A Health Economic Trial in Adult Patients Undergoing Open Colectomy MA402S23B301 | Phase4 | Bowel Obstruction | Terminated | 2012-03-01 | 2012-07-01 | ClinicalTrials.gov |
| NCT01349140 | EXPAREL Dose-Response for Single-Injection Femoral Nerve Blocks | Phase1 | Healthy Volunteers | Completed | 2012-02-01 | 2012-04-01 | ClinicalTrials.gov |
| NCT01509807 | A Health Economic Trial in Adult Patients Undergoing Ileostomy Reversal MA402S2… | Phase4 | Retraction of Colostomy | Completed | 2012-01-01 | 2012-10-01 | ClinicalTrials.gov |
| NCT01507246 | Adult Patients Undergoing Open Colectomy MA402S23B303 | Phase4 | Bowel Obstruction | Completed | 2011-12-01 | 2012-08-01 | ClinicalTrials.gov |
| NCT02058290 | A Health Economic Trial in Adult Patients Undergoing Laparoscopic Colectomy | Phase4 | Bowel Obstruction | Terminated | 2011-12-01 | 2013-02-01 | ClinicalTrials.gov |
| NCT01447342 | A Study to Evaluate the Safety and Effectiveness of the Cryo-Touch II Device fo… | Phase2 | Facial Wrinkles | Completed | 2011-09-01 | 2012-08-01 | ClinicalTrials.gov |
| NCT01379365 | Cryo-Touch III Refinement Study Investigational Plan | Phase2 | Facial Wrinkles | Completed | 2011-06-01 | 2014-12-01 | ClinicalTrials.gov |
| NCT01291914 | Study of FX005 for the Treatment of Pain in Patients With Osteoarthritis of the… | Phase1 | Osteoarthritis, Knee | Completed | 2010-12-01 | 2012-03-01 | ClinicalTrials.gov |
| NCT01167140 | Cryo-Touch II for the Treatment of Wrinkles | Phase2 | Facial Wrinkles | Completed | 2010-07-01 | 2011-04-01 | ClinicalTrials.gov |
| NCT01076686 | Observational Study to Assess Long-Term Follow-Up of Breast Augmentation Subjec… | — | Postoperative Pain | Completed | 2010-02-01 | 2010-03-01 | ClinicalTrials.gov |
| NCT00890721 | Study of Pain Control in Hemorrhoidectomy | Phase3 | Hemorrhoid | Completed | 2009-05-01 | 2009-11-01 | ClinicalTrials.gov |
| NCT00890682 | Study of Postoperative Analgesia in Bunionectomy | Phase3 | Bunion | Completed | 2009-04-01 | 2009-11-01 | ClinicalTrials.gov |
| NCT00842062 | Study of the MyoScience Tissue Remodeling Device for Facial Rejuvenation | Phase1 | Facial Rhytides | Completed | 2009-02-01 | 2012-01-01 | ClinicalTrials.gov |
| NCT00812305 | Hepatic Impairment Study: Pharmacokinetics in Healthy and Hepatically Impaired … | Phase1 | Pain | Completed | 2009-01-01 | 2009-08-01 | ClinicalTrials.gov |
| NCT00807209 | Dose Finding Posterolateral Thoracotomy Study | Phase2 | Postoperative Pain | Terminated | 2008-12-01 | 2009-02-01 | ClinicalTrials.gov |
| NCT00813111 | Phase 3 Study of Local Administration of SKY0402 for Postoperative Analgesia in… | Phase3 | Pain | Terminated | 2008-11-01 | 2009-02-01 | ClinicalTrials.gov |
| NCT00806806 | Evaluate the Onset of Action of SKY0402 Following Local Infiltration in Healthy… | Phase1 | Postoperative Pain Management | Completed | 2008-10-01 | 2009-02-01 | ClinicalTrials.gov |
| NCT00744848 | Study to Evaluate Postoperative Analgesia in Subjects Undergoing Hemorrhoidecto… | Phase3 | Hemorrhoids | Completed | 2008-08-01 | 2009-02-01 | ClinicalTrials.gov |
| NCT00745290 | A Phase 3 Study to Evaluate the Safety and Efficacy of SKY0402 in Subjects Unde… | Phase3 | Postoperative Pain | Completed | 2008-08-01 | 2009-02-01 | ClinicalTrials.gov |
| NCT01206608 | Evaluation of the Safety and Efficacy of a Single Dose of SKY0402 in Subjects U… | Phase2 | Postoperative Pain | Completed | 2008-03-01 | 2008-12-01 | ClinicalTrials.gov |
| NCT00529126 | Phase 2 Dose-Ranging Study of SKY0402 for Prolonged Postoperative Analgesia in … | Phase2 | Postoperative Pain | Completed | 2007-09-01 | 2008-07-01 | ClinicalTrials.gov |
| NCT00485693 | Dose-Ranging Study for Prolonged Postoperative Analgesia in Subject Undergoing … | Phase2 | Postoperative Pain | Completed | 2007-06-01 | 2009-08-01 | ClinicalTrials.gov |
| NCT00485667 | Phase 1 Thorough QT Study in Young Healthy Volunteers | Phase1 | Postoperative Pain | Completed | 2007-06-01 | 2007-08-01 | ClinicalTrials.gov |
| NCT00485433 | Dose-ranging Study for Postoperative Analgesia in Subjects Undergoing Primary U… | Phase2 | Postoperative Pain | Completed | 2007-06-01 | 2008-08-01 | ClinicalTrials.gov |
| NCT00130351 | A 3-week Study Investigating Patient Use and Functionality of Formoterol in a N… | Phase3 | Asthma | Completed | 2005-07-01 | 2005-08-01 | ClinicalTrials.gov |
| NCT01206595 | Safety, Efficacy, and Pharmacokinetics of SKY0402 Administered as a Nerve Block… | Phase2 | Postoperative Pain | Completed | 2005-03-01 | 2006-12-01 | ClinicalTrials.gov |
| NCT01203644 | Evaluation of the Safety, Efficacy, and Pharmacokinetics of SKY0402 in Subjects… | Phase2 | Inguinal Hernia | Completed | 2004-12-01 | 2006-12-01 | ClinicalTrials.gov |
| NCT00134979 | Formoterol Certihaler, Tiotropium HandiHaler and Tiotropium HandiHaler in Combi… | Phase4 | Chronic Obstructive Pulmonary Disease | Completed | 2004-10-01 | 2005-11-01 | ClinicalTrials.gov |
| NCT00728832 | A Pharmacokinetic (PK) Study of Extended-Release Epidural Morphine in Upper Abd… | Phase1 | Postoperative Pain | Completed | 2002-05-01 | — | ClinicalTrials.gov |
| NCT00029523 | DepoCyt Therapy in Patients With Neoplastic Meningitis From Lymphoma or a Solid… | Phase4 | Meningeal Neoplasms | Completed | 2001-04-01 | 2004-11-01 | ClinicalTrials.gov |
| NCT00003073 | Chemotherapy in Treating Young Patients With Recurrent or Refractory Meningeal … | Phase1 | Brain and Central Nervous System Tumors | Unknown | 1997-02-01 | — | ClinicalTrials.gov |
| Product Name | Type | Development Stage | Therapeutic Area | Study Status | Trial ID |
|---|---|---|---|---|---|
| Radiofrequency ablation (RFA) | Other | Approved | Low Back Pain, Chronic | RECRUITING | NCT07214844 |
| Iovera Medial Branch Cryoneurolysis | Other | Approved | Low Back Pain, Chronic | RECRUITING | NCT07214844 |
| Treatment for Knee OA | Drug | Preclinical | Knee Osteoarthritis | RECRUITING | NCT05495334 |
| Treatment for Knee OA | Drug | Preclinical | Knee Osteoarthritis | RECRUITING | NCT05495334 |
| Placebo | Other | Phase PHASE3 | Glenohumeral Osteoarthritis | ACTIVE_NOT_RECRUITING | NCT06269705 |
| ZILRETTA | Other | Phase PHASE3 | Glenohumeral Osteoarthritis | ACTIVE_NOT_RECRUITING | NCT06269705 |
| Treatment for Knee OA | Drug | Preclinical | Knee Osteoarthritis | RECRUITING | NCT05495334 |
| Treatment for Knee OA | Drug | Preclinical | Knee Osteoarthritis | RECRUITING | NCT05495334 |
| Treatment for Knee OA | Drug | Preclinical | Knee Osteoarthritis | RECRUITING | NCT05495334 |
| Treatment for Knee OA | Drug | Preclinical | Knee Osteoarthritis | RECRUITING | NCT05495334 |
| Treatment for Knee OA | Drug | Preclinical | Knee Osteoarthritis | RECRUITING | NCT05495334 |
| Thoracic epidural analgesia (bupivacaine) | Other | Phase PHASE3 | Surgery | COMPLETED | NCT04117074 |
| Liposomal bupivacaine | Other | Phase PHASE3 | Surgery | COMPLETED | NCT04117074 |
| Thoracic epidural analgesia (bupivacaine) | Other | Phase PHASE3 | Surgery | COMPLETED | NCT04117074 |
| Liposomal bupivacaine | Other | Phase PHASE3 | Surgery | COMPLETED | NCT04117074 |
| Thoracic epidural analgesia (bupivacaine) | Other | Phase PHASE3 | Surgery | COMPLETED | NCT04117074 |
| Liposomal bupivacaine | Other | Phase PHASE3 | Surgery | COMPLETED | NCT04117074 |
| Thoracic epidural analgesia (bupivacaine) | Other | Phase PHASE3 | Surgery | COMPLETED | NCT04117074 |
| Liposomal bupivacaine | Other | Phase PHASE3 | Surgery | COMPLETED | NCT04117074 |
| Thoracic epidural analgesia (bupivacaine) | Other | Phase PHASE3 | Surgery | COMPLETED | NCT04117074 |
| Liposomal bupivacaine | Other | Phase PHASE3 | Surgery | COMPLETED | NCT04117074 |
| Thoracic epidural analgesia (bupivacaine) | Other | Phase PHASE3 | Surgery | COMPLETED | NCT04117074 |
| Liposomal bupivacaine | Other | Phase PHASE3 | Surgery | COMPLETED | NCT04117074 |
| Thoracic epidural analgesia (bupivacaine) | Other | Phase PHASE3 | Surgery | COMPLETED | NCT04117074 |
| Liposomal bupivacaine | Other | Phase PHASE3 | Surgery | COMPLETED | NCT04117074 |
| Thoracic epidural analgesia (bupivacaine) | Other | Phase PHASE3 | Surgery | COMPLETED | NCT04117074 |
| Liposomal bupivacaine | Other | Phase PHASE3 | Surgery | COMPLETED | NCT04117074 |
| Thoracic epidural analgesia (bupivacaine) | Other | Phase PHASE3 | Surgery | COMPLETED | NCT04117074 |
| Liposomal bupivacaine | Other | Phase PHASE3 | Surgery | COMPLETED | NCT04117074 |
| Thoracic epidural analgesia (bupivacaine) | Other | Phase PHASE3 | Surgery | COMPLETED | NCT04117074 |
| Liposomal bupivacaine | Other | Phase PHASE3 | Surgery | COMPLETED | NCT04117074 |
| Thoracic epidural analgesia (bupivacaine) | Other | Phase PHASE3 | Surgery | COMPLETED | NCT04117074 |
| Liposomal bupivacaine | Other | Phase PHASE3 | Surgery | COMPLETED | NCT04117074 |
| Thoracic epidural analgesia (bupivacaine) | Other | Phase PHASE3 | Surgery | COMPLETED | NCT04117074 |
| Liposomal bupivacaine | Other | Phase PHASE3 | Surgery | COMPLETED | NCT04117074 |
| Thoracic epidural analgesia (bupivacaine) | Other | Phase PHASE3 | Surgery | COMPLETED | NCT04117074 |
| Liposomal bupivacaine | Other | Phase PHASE3 | Surgery | COMPLETED | NCT04117074 |
| Thoracic epidural analgesia (bupivacaine) | Other | Phase PHASE3 | Surgery | COMPLETED | NCT04117074 |
| Liposomal bupivacaine | Other | Phase PHASE3 | Surgery | COMPLETED | NCT04117074 |
| Thoracic epidural analgesia (bupivacaine) | Other | Phase PHASE3 | Surgery | COMPLETED | NCT04117074 |
| Liposomal bupivacaine | Other | Phase PHASE3 | Surgery | COMPLETED | NCT04117074 |
| Thoracic epidural analgesia (bupivacaine) | Other | Phase PHASE3 | Surgery | COMPLETED | NCT04117074 |
| Liposomal bupivacaine | Other | Phase PHASE3 | Surgery | COMPLETED | NCT04117074 |
| Bupivacaine liposome injectable suspension (LIA) | Other | Phase PHASE4 | Total Knee Arthroplasty | ENROLLING_BY_INVITATION | NCT07584915 |
| Bupivacaine liposome injectable suspension (IPSA block) | Other | Phase PHASE4 | Total Knee Arthroplasty | ENROLLING_BY_INVITATION | NCT07584915 |
| Local Infiltration Analgesia (LIA) | Other | Phase PHASE4 | Total Knee Arthroplasty | ENROLLING_BY_INVITATION | NCT07584915 |
| Intra-articular Posteromedial Surgeon Administered (IPSA) Block with LIA | Other | Phase PHASE4 | Total Knee Arthroplasty | ENROLLING_BY_INVITATION | NCT07584915 |
| Bupivacaine liposome injectable suspension (LIA) | Other | Phase PHASE4 | Total Knee Arthroplasty | ENROLLING_BY_INVITATION | NCT07584915 |
| Bupivacaine liposome injectable suspension (IPSA block) | Other | Phase PHASE4 | Total Knee Arthroplasty | ENROLLING_BY_INVITATION | NCT07584915 |
| Local Infiltration Analgesia (LIA) | Other | Phase PHASE4 | Total Knee Arthroplasty | ENROLLING_BY_INVITATION | NCT07584915 |
| Intra-articular Posteromedial Surgeon Administered (IPSA) Block with LIA | Other | Phase PHASE4 | Total Knee Arthroplasty | ENROLLING_BY_INVITATION | NCT07584915 |
| Bupivacaine liposome injectable suspension (LIA) | Other | Phase PHASE4 | Total Knee Arthroplasty | ENROLLING_BY_INVITATION | NCT07584915 |
| Bupivacaine liposome injectable suspension (IPSA block) | Other | Phase PHASE4 | Total Knee Arthroplasty | ENROLLING_BY_INVITATION | NCT07584915 |
| Local Infiltration Analgesia (LIA) | Other | Phase PHASE4 | Total Knee Arthroplasty | ENROLLING_BY_INVITATION | NCT07584915 |
| Intra-articular Posteromedial Surgeon Administered (IPSA) Block with LIA | Other | Phase PHASE4 | Total Knee Arthroplasty | ENROLLING_BY_INVITATION | NCT07584915 |
| Bupivacaine liposome injectable suspension (LIA) | Other | Phase PHASE4 | Total Knee Arthroplasty | ENROLLING_BY_INVITATION | NCT07584915 |
| Bupivacaine liposome injectable suspension (IPSA block) | Other | Phase PHASE4 | Total Knee Arthroplasty | ENROLLING_BY_INVITATION | NCT07584915 |
| Local Infiltration Analgesia (LIA) | Other | Phase PHASE4 | Total Knee Arthroplasty | ENROLLING_BY_INVITATION | NCT07584915 |
| Intra-articular Posteromedial Surgeon Administered (IPSA) Block with LIA | Other | Phase PHASE4 | Total Knee Arthroplasty | ENROLLING_BY_INVITATION | NCT07584915 |
| Bupivacaine liposome injectable suspension (LIA) | Other | Phase PHASE4 | Total Knee Arthroplasty | ENROLLING_BY_INVITATION | NCT07584915 |
| Bupivacaine liposome injectable suspension (IPSA block) | Other | Phase PHASE4 | Total Knee Arthroplasty | ENROLLING_BY_INVITATION | NCT07584915 |
| Local Infiltration Analgesia (LIA) | Other | Phase PHASE4 | Total Knee Arthroplasty | ENROLLING_BY_INVITATION | NCT07584915 |
| Intra-articular Posteromedial Surgeon Administered (IPSA) Block with LIA | Other | Phase PHASE4 | Total Knee Arthroplasty | ENROLLING_BY_INVITATION | NCT07584915 |
| Cryoneurolysis | Other | Approved | ACL Repair | RECRUITING | NCT06603051 |
| Bupivacaine liposome injectable suspension (LIA) | Other | Phase PHASE4 | Total Knee Arthroplasty | ENROLLING_BY_INVITATION | NCT07584915 |
| Bupivacaine liposome injectable suspension (IPSA block) | Other | Phase PHASE4 | Total Knee Arthroplasty | ENROLLING_BY_INVITATION | NCT07584915 |
| Local Infiltration Analgesia (LIA) | Other | Phase PHASE4 | Total Knee Arthroplasty | ENROLLING_BY_INVITATION | NCT07584915 |
| Intra-articular Posteromedial Surgeon Administered (IPSA) Block with LIA | Other | Phase PHASE4 | Total Knee Arthroplasty | ENROLLING_BY_INVITATION | NCT07584915 |
| Cryoneurolysis | Other | Approved | ACL Repair | RECRUITING | NCT06603051 |
| Cryoneurolysis | Other | Approved | ACL Repair | RECRUITING | NCT06603051 |
| Cryoneurolysis | Other | Approved | ACL Repair | RECRUITING | NCT06603051 |
| Cryoneurolysis | Other | Approved | ACL Repair | RECRUITING | NCT06603051 |
| Cryoneurolysis | Other | Approved | ACL Repair | RECRUITING | NCT06603051 |
| Cryo-Touch III Device | Device | Approved | Entrapment Neuropathy | COMPLETED | NCT01753778 |
| EXPAREL | Other | Phase PHASE4 | Retraction of Colostomy | COMPLETED | NCT01509807 |
| IV morphine sulfate or Sponsor-approved equivalent | Other | Phase PHASE4 | Retraction of Colostomy | COMPLETED | NCT01509807 |
| EXPAREL | Other | Phase PHASE1 | Postoperative Pain Management | TERMINATED | NCT03428984 |
| EXPAREL 266 mg | Other | Phase PHASE2 | Postoperative Pain | COMPLETED | NCT01683071 |
| EXPAREL 133 mg | Other | Phase PHASE2 | Postoperative Pain | COMPLETED | NCT01683071 |
| EXPAREL 67 mg | Other | Phase PHASE2 | Postoperative Pain | COMPLETED | NCT01683071 |
| Placebo | Other | Phase PHASE2 | Postoperative Pain | COMPLETED | NCT01683071 |
| Bupivacaine HCl | Other | Phase PHASE2 | Postoperative Pain | COMPLETED | NCT01206595 |
| SKY0402 | Other | Phase PHASE2 | Postoperative Pain | COMPLETED | NCT01206595 |
| Bupivacaine HCl | Other | Phase PHASE2 | Inguinal Hernia | COMPLETED | NCT01203644 |
| SKY0402 | Other | Phase PHASE2 | Inguinal Hernia | COMPLETED | NCT01203644 |
| EXPAREL Infiltration | Other | Phase PHASE4 | Pain | COMPLETED | NCT02284386 |
| Bupivacaine SNB | Other | Phase PHASE4 | Pain | COMPLETED | NCT02284386 |
| Bupivacaine Hydrochloride | Other | Phase PHASE1 | Breast Augmentation | COMPLETED | NCT04293809 |
| Exparel Injectable Product | Other | Phase PHASE1 | Breast Augmentation | COMPLETED | NCT04293809 |
| Bupivacaine supraclavicular block | Other | Phase PHASE4 | Hand Injuries | TERMINATED | NCT02058303 |
| Exparel Forearm block | Other | Phase PHASE4 | Hand Injuries | TERMINATED | NCT02058303 |
| Questionnaire and Physical Exam | Other | Preclinical | Postoperative Pain | COMPLETED | NCT01076686 |
| EXPAREL (bupivacaine liposome injectable suspension) | Other | Phase PHASE4 | Bowel Obstruction | COMPLETED | NCT01507246 |
| IV morphine sulfate | Other | Phase PHASE4 | Bowel Obstruction | COMPLETED | NCT01507246 |
| Group 2 EXPAREL | Other | Phase PHASE4 | Retraction of Colostomy | COMPLETED | NCT01509638 |
| Group 1 Standard of Care | Other | Phase PHASE4 | Retraction of Colostomy | COMPLETED | NCT01509638 |
| EXPAREL (bupivacaine liposome injectable suspension) | Other | Phase PHASE4 | Bowel Obstruction | TERMINATED | NCT01507233 |
| IV morphine sulfate | Other | Phase PHASE4 | Bowel Obstruction | TERMINATED | NCT01507233 |
| bupivacaine liposome extended-release injectable suspension | Other | Phase PHASE4 | Bowel Obstruction | TERMINATED | NCT01507220 |
| morphine sulfate | Other | Phase PHASE4 | Bowel Obstruction | TERMINATED | NCT01507220 |
| EXPAREL | Other | Phase PHASE4 | Bowel Obstruction | TERMINATED | NCT02058290 |
| IV morphine sulfate or Sponsor-approved equivalent | Other | Phase PHASE4 | Bowel Obstruction | TERMINATED | NCT02058290 |
| On-Q Pain Ball | Other | Phase PHASE4 | Obesity | COMPLETED | NCT02142829 |
| EXPAREL | Other | Phase PHASE4 | Obesity | COMPLETED | NCT02142829 |
| Infiltration - EXPAREL | Other | Phase PHASE4 | Mammoplasty | COMPLETED | NCT01582490 |
| Instillation - EXPAREL | Other | Phase PHASE4 | Mammoplasty | COMPLETED | NCT01582490 |
| Cryotherapy for the utilization of wrinkle reduction (iovera) | Drug | Preclinical | Wrinkles | COMPLETED | NCT01984619 |
| iovera | Other | Approved | Forehead Wrinkles | COMPLETED | NCT01950065 |
| Treatment with CryoTouch III Device | Drug | Preclinical | Frown Lines | COMPLETED | NCT01808742 |
| Treatment with CryoTouch IV | Drug | Preclinical | Frown Lines | COMPLETED | NCT01801826 |
| Cryo-Touch II | Other | Phase PHASE2 | Facial Wrinkles | COMPLETED | NCT01447342 |
| Cryo-Touch III | Other | Phase PHASE2 | Facial Wrinkles | COMPLETED | NCT01379365 |
| Bupivacaine block in shoulder surgery | Procedure | Approved | Injury of Shoulder Region | COMPLETED | NCT02554357 |
| Exparel block in arthroscopic shoulder surgery | Procedure | Approved | Injury of Shoulder Region | COMPLETED | NCT02554357 |
| Continuous Perineural Ropivicaine Infusion | Other | Phase PHASE4 | Postoperative Pain | TERMINATED | NCT02787226 |
| Liposomal Bupivacaine Infiltration | Other | Phase PHASE4 | Postoperative Pain | TERMINATED | NCT02787226 |
| MRI | Other | Preclinical | Hematoma | COMPLETED | NCT02821325 |
| EXPAREL | Other | Phase PHASE1 | Spinal Fusion | COMPLETED | NCT02985762 |
| iovera° | Other | Approved | Anterior Cruciate Ligament Reconstruction | WITHDRAWN | NCT03688477 |
| iovera° | Other | Approved | ACL Reconstruction | WITHDRAWN | NCT03909516 |
| Bupivacaine Hcl 0.25% Inj | Other | Phase PHASE4 | Post Operative Pain | UNKNOWN | NCT03975283 |
| Exparel 266 MG Per 20 ML Injection | Other | Phase PHASE4 | Post Operative Pain | UNKNOWN | NCT03975283 |
| iovera° | Other | Approved | Arthropathy of Knee | WITHDRAWN | NCT03836313 |
| Ropivacaine | Other | Phase PHASE2 | Chronic Shoulder Pain | NOT_YET_RECRUITING | NCT03739021 |
| Exparel | Other | Phase PHASE2 | Chronic Shoulder Pain | NOT_YET_RECRUITING | NCT03739021 |
| Placebo | Other | Phase PHASE4 | Rotator Cuff Tear | COMPLETED | NCT03149887 |
| Liposomal bupivacaine | Other | Phase PHASE4 | Rotator Cuff Tear | COMPLETED | NCT03149887 |
| Bupivacaine Hydrochloride | Other | Phase PHASE4 | Hip Fractures | WITHDRAWN | NCT03955458 |
| Ropivacaine | Other | Phase PHASE4 | Hip Fractures | WITHDRAWN | NCT03955458 |
| EXPAREL | Other | Phase PHASE4 | Hip Fractures | WITHDRAWN | NCT03955458 |
| EXPAREL® infiltration | Other | Preclinical | Pain Management | WITHDRAWN | NCT03076710 |
| Opioids delivered through PCA | Other | Preclinical | Pain Management | WITHDRAWN | NCT03076710 |
| Bupivacaine Hydrochloride | Other | Phase PHASE3 | Bunion | WITHDRAWN | NCT03954639 |
| EXPAREL 13.3Mg/mL Suspension for Injection | Other | Phase PHASE3 | Bunion | WITHDRAWN | NCT03954639 |
| Liposome bupivacaine + bupivacaine | Other | Phase PHASE2 | Dupuytren's Contracture of the Hand (Viking's Disease) | COMPLETED | NCT03106519 |
| Liposome bupivacaine | Other | Phase PHASE2 | Hallux Valgus (Bunions) | COMPLETED | NCT03106545 |
| Exparel | Other | Phase PHASE4 | Ankle Arthrodesis | COMPLETED | NCT02586077 |
| Placebo | Other | Phase PHASE3 | Pain | COMPLETED | NCT02713178 |
| bupivacaine liposome injectable suspension | Other | Phase PHASE3 | Pain | COMPLETED | NCT02713178 |
| Placebo | Other | Phase PHASE3 | Pain | COMPLETED | NCT02713230 |
| bupivacaine liposome injectable suspension | Other | Phase PHASE3 | Pain | COMPLETED | NCT02713230 |
| Placebo | Other | Phase PHASE3 | Dental Pain | COMPLETED | NCT02517905 |
| Bupivacaine liposome | Other | Phase PHASE3 | Dental Pain | COMPLETED | NCT02517905 |
| Tranexamic Acid | Other | Phase PHASE2 | Total Knee Arthroplasty | TERMINATED | NCT02922582 |
| DepoTXA | Other | Phase PHASE2 | Total Knee Arthroplasty | TERMINATED | NCT02922582 |
| Bupivacaine | Other | Phase PHASE4 | Pain | COMPLETED | NCT02713490 |
| EXPAREL | Other | Phase PHASE4 | Pain | COMPLETED | NCT02713490 |
| Standard Bupivacaine | Other | Phase PHASE4 | Male Infertility | COMPLETED | NCT03802864 |
| Liposomal Bupivacaine | Other | Phase PHASE4 | Male Infertility | COMPLETED | NCT03802864 |
| 0.5% Bupivacaine HCl | Other | Phase PHASE3 | Postoperative Pain Management | COMPLETED | NCT03682302 |
| Exparel | Other | Phase PHASE3 | Postoperative Pain Management | COMPLETED | NCT03682302 |
| Bupivacaine | Other | Phase PHASE4 | C-Section | COMPLETED | NCT03176459 |
| Exparel + Bupivacaine | Other | Phase PHASE4 | C-Section | COMPLETED | NCT03176459 |
| Bupivacaine | Other | Phase PHASE1 | Bunion | COMPLETED | NCT04002089 |
| Exparel Injectable Product | Other | Phase PHASE1 | Bunion | COMPLETED | NCT04002089 |
| EXPAREL | Other | Phase PHASE4 | Postoperative Pain | TERMINATED | NCT01919606 |
| Mid-dose SKY0402 + bupivacaine HCl | Other | Phase PHASE2 | Postoperative Pain | COMPLETED | NCT01206608 |
| SKY0402 + bupivacaine HCl | Other | Phase PHASE2 | Postoperative Pain | COMPLETED | NCT01206608 |
| EXPAREL Infiltration | Other | Phase PHASE4 | Pain | COMPLETED | NCT02255500 |
| Bupivacaine FNB | Other | Phase PHASE4 | Pain | COMPLETED | NCT02255500 |
| EXPAREL | Other | Phase PHASE4 | Pain | COMPLETED | NCT02199574 |
| EXPAREL | Other | Phase PHASE4 | Hernia | COMPLETED | NCT01801124 |
| SKY0402 | Other | Phase PHASE1 | Healthy Volunteers | COMPLETED | NCT01349140 |
| EXPAREL | Other | Phase PHASE4 | Pain | TERMINATED | NCT02353754 |
| Intrathecal morphine injection | Other | Phase PHASE4 | Pain | TERMINATED | NCT02353754 |
| Placebo | Other | Phase PHASE1 | Healthy | TERMINATED | NCT04173611 |
| Bupivacaine Hydrochloride | Other | Phase PHASE1 | Healthy | TERMINATED | NCT04173611 |
| EXPAREL | Other | Phase PHASE1 | Healthy | TERMINATED | NCT04173611 |
| iovera° | Other | Approved | Total Knee Arthroplasty | COMPLETED | NCT03327220 |
| EXPAREL 40 mL | Other | Phase PHASE4 | Postsurgical Pain | COMPLETED | NCT01582477 |
| EXPAREL 20 mL | Other | Phase PHASE4 | Postsurgical Pain | COMPLETED | NCT01582477 |
| Placebo | Other | Phase PHASE4 | Pain | TERMINATED | NCT01919190 |
| EXPAREL | Other | Phase PHASE4 | Pain | TERMINATED | NCT01919190 |
| EXPAREL | Other | Phase PHASE1 | Healthy Volunteers | COMPLETED | NCT02210247 |
| Placebo | Other | Phase PHASE3 | Posterolateral Thoracotomy | COMPLETED | NCT01802411 |
| EXPAREL 266 mg | Other | Phase PHASE3 | Posterolateral Thoracotomy | COMPLETED | NCT01802411 |
| Bupivacaine Hydrochloride | Other | Phase PHASE3 | Coronary Artery Disease | COMPLETED | NCT03270514 |
| Exparel Injectable Product | Other | Phase PHASE3 | Coronary Artery Disease | COMPLETED | NCT03270514 |
| Placebo | Other | Phase PHASE4 | Analgesia, Postoperative | COMPLETED | NCT03541941 |
| Bupivacaine Hcl 0.25% Inj | Other | Phase PHASE4 | Analgesia, Postoperative | COMPLETED | NCT03541941 |
| Exparel | Other | Phase PHASE4 | Analgesia, Postoperative | COMPLETED | NCT03541941 |
| Bupivacaine HCl | Other | Phase PHASE4 | Postoperative Pain Management | TERMINATED | NCT03015961 |
| EXPAREL and bupivacaine HCl | Other | Phase PHASE4 | Postoperative Pain Management | TERMINATED | NCT03015961 |
| Bupivacaine Hydrochloride | Other | Phase PHASE4 | Vaginal Hysterectomy | TERMINATED | NCT03907033 |
| Liposomal bupivacaine | Other | Phase PHASE4 | Vaginal Hysterectomy | TERMINATED | NCT03907033 |
| Symptom Questionnaire | Other | Phase PHASE3 | Malignant Neoplasms of Female Genital Organs | TERMINATED | NCT02740114 |
| Pill Diary | Other | Phase PHASE3 | Malignant Neoplasms of Female Genital Organs | TERMINATED | NCT02740114 |
| Oxycodone | Other | Phase PHASE3 | Malignant Neoplasms of Female Genital Organs | TERMINATED | NCT02740114 |
| Liposomal Bupivacaine | Other | Phase PHASE3 | Malignant Neoplasms of Female Genital Organs | TERMINATED | NCT02740114 |
| Bupivacaine | Other | Phase PHASE3 | Malignant Neoplasms of Female Genital Organs | TERMINATED | NCT02740114 |
| Standard of Care | Other | Phase PHASE4 | Postoperative Pain Management | TERMINATED | NCT03927911 |
| EXPAREL and Bupivacaine | Other | Phase PHASE4 | Postoperative Pain Management | TERMINATED | NCT03927911 |
| Triamcinolone Acetonide Extended-Release Injectable Suspension | Other | Phase PHASE1 | Osteoarthritis, Knee | COMPLETED | NCT04261049 |
| Bupivacaine hydrochloride (HCl) | Other | Phase PHASE4 | Pain, Postoperative | COMPLETED | NCT04278846 |
| Depofoam bupivacaine | Other | Phase PHASE4 | Pain, Postoperative | COMPLETED | NCT04278846 |
| Bupivacaine Hydrochloride | Other | Phase PHASE3 | Lower Extremity Surgery | COMPLETED | NCT04518462 |
| Exparel | Other | Phase PHASE3 | Lower Extremity Surgery | COMPLETED | NCT04518462 |
| Exparel TAP + multi-modal pain regimen | Other | Phase PHASE4 | Elective Cesarean Section | COMPLETED | NCT03853694 |
| 150 mcg Duramorph + multi-modal pain regimen | Other | Phase PHASE4 | Elective Cesarean Section | COMPLETED | NCT03853694 |
| 50 mcg Duramorph+ EXPAREL + multi-modal pain regimen | Other | Phase PHASE4 | Elective Cesarean Section | COMPLETED | NCT03853694 |
| Normal Saline | Other | Phase PHASE1 | Pain, Postoperative | COMPLETED | NCT04826328 |
| FX301 | Other | Phase PHASE1 | Pain, Postoperative | COMPLETED | NCT04826328 |
| Cryoanalgesia (iovera°®) | Other | Approved | Morton's Neuroma | UNKNOWN | NCT05604144 |
| ioveraº sham | Other | Approved | Post-Operative Pain Management | TERMINATED | NCT04191031 |
| ioveraº | Other | Approved | Post-Operative Pain Management | TERMINATED | NCT04191031 |
| Sham cryoneurolysis procedure | Procedure | Approved | Mastectomy | COMPLETED | NCT03578237 |
| Cryoneurolysis (active) | Other | Approved | Mastectomy | COMPLETED | NCT03578237 |
| Exparel | Other | Phase PHASE1 | Postoperative Pain Management | COMPLETED | NCT03485014 |
| FX006 | Other | Phase PHASE2 | Trochanteric Bursitis | COMPLETED | NCT04182672 |
| Normal Saline | Other | Phase PHASE2 | Osteoarthritis of the Shoulder | TERMINATED | NCT04160091 |
| FX006 | Other | Phase PHASE2 | Osteoarthritis of the Shoulder | TERMINATED | NCT04160091 |
| FX006 32 mg | Other | Phase PHASE2 | Osteoarthritis, Hip | COMPLETED | NCT04065074 |
| Normal saline | Other | Phase PHASE3 | Osteoarthritis, Hip | TERMINATED | NCT03793010 |
| FX006 | Other | Phase PHASE3 | Osteoarthritis, Hip | TERMINATED | NCT03793010 |
| FX006 32 mg | Other | Phase PHASE3 | Osteoarthritis, Knee | COMPLETED | NCT03529942 |
| TAcs 40 mg | Other | Phase PHASE2 | Osteoarthritis of the Shoulder | COMPLETED | NCT03382262 |
| FX006 32 mg | Other | Phase PHASE2 | Osteoarthritis of the Shoulder | COMPLETED | NCT03382262 |
| TAcs 40 mg | Other | Phase PHASE2 | Bilateral Knee Osteoarthritis | COMPLETED | NCT03378076 |
| FX006 32 mg | Other | Phase PHASE2 | Bilateral Knee Osteoarthritis | COMPLETED | NCT03378076 |
| FX006 32 mg | Other | Phase PHASE3 | Osteoarthritis of the Knee | COMPLETED | NCT03046446 |
| TCA IR 40 mg | Other | Phase PHASE2 | Osteoarthritis of the Knee | COMPLETED | NCT02762370 |
| FX006 32 mg | Other | Phase PHASE2 | Osteoarthritis of the Knee | COMPLETED | NCT02762370 |
| TCA IR 40 | Other | Phase PHASE2 | Osteoarthritis of the Knee | COMPLETED | NCT02637323 |
| FX006 32 mg | Other | Phase PHASE2 | Osteoarthritis of the Knee | COMPLETED | NCT02637323 |
| TCA IR 40 mg | Other | Phase PHASE2 | Post-traumatic Osteoarthritis of the Knee | TERMINATED | NCT02468583 |
| FX006 32 mg | Other | Phase PHASE2 | Post-traumatic Osteoarthritis of the Knee | TERMINATED | NCT02468583 |
| TCA IR 40 | Other | Phase PHASE3 | Osteoarthritis of the Knee | COMPLETED | NCT02357459 |
| Placebo | Other | Phase PHASE3 | Osteoarthritis of the Knee | COMPLETED | NCT02357459 |
| FX006 | Other | Phase PHASE3 | Osteoarthritis of the Knee | COMPLETED | NCT02357459 |
| iovera° Sham | Other | Approved | Arthritis of the Knee | COMPLETED | NCT02284113 |
| iovera° | Other | Approved | Arthritis of the Knee | COMPLETED | NCT02284113 |
| Sham Comparator | Other | Approved | Knee Osteoarthritis | COMPLETED | NCT02260921 |
| iovera° | Other | Approved | Knee Osteoarthritis | COMPLETED | NCT02260921 |
| FX006 16 mg | Other | Phase PHASE2 | Osteoarthritis of the Knee | COMPLETED | NCT02116972 |
| Placebo | Other | Phase PHASE2 | Osteoarthritis of the Knee | COMPLETED | NCT02116972 |
| FX006 32 mg | Other | Phase PHASE2 | Osteoarthritis of the Knee | COMPLETED | NCT02116972 |
| TCA IR 40 mg | Other | Phase PHASE2 | Osteoarthritis of the Knee | COMPLETED | NCT02003365 |
| FX006 40 mg | Other | Phase PHASE2 | Osteoarthritis of the Knee | COMPLETED | NCT02003365 |
| FX006 10 mg | Other | Phase PHASE2 | Osteoarthritis of the Knee | COMPLETED | NCT02003365 |
| Treatment with Cryo-Touch III device | Drug | Approved | Upper Limb Spasticity | COMPLETED | NCT01863901 |
| Device: Cryo-Touch III Study treatment at Day 0. | Drug | Approved | Occipital Neuralgia | COMPLETED | NCT01753765 |
| Cryo-Touch III | Other | Approved | Osteoarthritis of the Knee | COMPLETED | NCT01704157 |
| Cryo-Touch III | Other | Approved | Histological Response of Tissue to Cold | COMPLETED | NCT01681745 |
| TCA IR 40 | Other | Phase PHASE2 | Osteoarthritis of the Knee | COMPLETED | NCT01487200 |
| FX006 60 mg | Other | Phase PHASE2 | Osteoarthritis of the Knee | COMPLETED | NCT01487200 |
| FX006 40 mg | Other | Phase PHASE2 | Osteoarthritis of the Knee | COMPLETED | NCT01487200 |
| FX006 10 mg | Other | Phase PHASE2 | Osteoarthritis of the Knee | COMPLETED | NCT01487200 |
| TCA IR | Other | Phase PHASE2 | Osteoarthritis of the Knee | COMPLETED | NCT01487161 |
| FX006 | Other | Phase PHASE2 | Osteoarthritis of the Knee | COMPLETED | NCT01487161 |
| Placebo 2 (Diluent) | Other | Phase PHASE1 | Osteoarthritis, Knee | COMPLETED | NCT01291914 |
| Placebo 1 (Carrier) | Other | Phase PHASE1 | Osteoarthritis, Knee | COMPLETED | NCT01291914 |
| FX005 | Other | Phase PHASE1 | Osteoarthritis, Knee | COMPLETED | NCT01291914 |
| Cryo-Touch II | Other | Phase PHASE2 | Facial Wrinkles | COMPLETED | NCT01167140 |
| Ropivacaine | Other | Phase PHASE4 | Rotator Cuff Injury | COMPLETED | NCT03738696 |
| Exparel | Other | Phase PHASE4 | Rotator Cuff Injury | COMPLETED | NCT03738696 |
| Liposomal bupivacaine (LB, Exparel) | Other | Phase PHASE4 | Adolescent Idiopathic Scoliosis | COMPLETED | NCT05730920 |
| Methadone | Other | Phase PHASE4 | Adolescent Idiopathic Scoliosis | COMPLETED | NCT05730920 |
| Bupivacaine Hydrochloride | Other | Phase PHASE3 | Knee Osteoarthritis | COMPLETED | NCT05139030 |
| bupivacaine liposome injectable suspension | Other | Phase PHASE3 | Knee Osteoarthritis | COMPLETED | NCT05139030 |
| Radiofrequency ablation | Other | Approved | Low Back Pain | COMPLETED | NCT06016127 |
| iovera system | Other | Approved | Low Back Pain | COMPLETED | NCT06016127 |
| Cryoneurolysis | Other | Approved | ACL Repair | RECRUITING | NCT06603051 |
| Bupivacain | Other | Phase PHASE2 | Back Pain | ENROLLING_BY_INVITATION | NCT06350981 |
| Exparel | Other | Phase PHASE2 | Back Pain | ENROLLING_BY_INVITATION | NCT06350981 |
| Acetaminophen 500Mg Cap | Other | Preclinical | ACL Tear | COMPLETED | NCT06340932 |
| Bupivacaine Hydrochloride | Other | Preclinical | ACL Tear | COMPLETED | NCT06340932 |
| Tramadol | Other | Preclinical | ACL Tear | COMPLETED | NCT06340932 |
| Oxycodone | Other | Preclinical | ACL Tear | COMPLETED | NCT06340932 |
| Acetaminophen | Other | Preclinical | ACL Tear | COMPLETED | NCT06340932 |
| Celecoxib | Other | Preclinical | ACL Tear | COMPLETED | NCT06340932 |
| Iovera | Other | Preclinical | ACL Tear | COMPLETED | NCT06340932 |
| Placebo | Other | Phase PHASE1 | Healthy | COMPLETED | NCT05456490 |
| Bupivacaine | Other | Phase PHASE1 | Healthy | COMPLETED | NCT05456490 |
| Liposomal Bupivacaine 13.3 | Other | Phase PHASE1 | Healthy | COMPLETED | NCT05456490 |
| FX201 | Other | Phase PHASE1 | Osteoarthritis, Knee | ACTIVE_NOT_RECRUITING | NCT04119687 |
| EXPAREL 1.3 % in 20 ML Injection | Other | Phase PHASE4 | Rotator Cuff Tear | TERMINATED | NCT03290196 |
| Radiofrequency ablation | Other | Approved | Chronic Sacroiliac Joint Pain | NOT_YET_RECRUITING | NCT06935539 |
| Cryoneurolysis | Other | Approved | Chronic Sacroiliac Joint Pain | NOT_YET_RECRUITING | NCT06935539 |
| Thoracic epidural analgesia (bupivacaine) | Other | Phase PHASE3 | Surgery | COMPLETED | NCT04117074 |
| Liposomal bupivacaine | Other | Phase PHASE3 | Surgery | COMPLETED | NCT04117074 |
| Bupivacaine liposome injectable suspension 133 mg | Other | Phase PHASE3 | Bunionectomy | COMPLETED | NCT05157841 |
| Bupivacaine HCl | Other | Phase PHASE3 | Bunionectomy | COMPLETED | NCT05157841 |
| Bupivacaine liposome injectable suspension 266 mg | Other | Phase PHASE3 | Bunionectomy | COMPLETED | NCT05157841 |
| Sham Cryoanalgesia | Other | Approved | Postoperative Pain | WITHDRAWN | NCT06284109 |
| Cryoanalgesia | Other | Approved | Postoperative Pain | WITHDRAWN | NCT06284109 |
| No cryoneurolysis | Other | Approved | Degenerative Joint Disease of Shoulder | RECRUITING | NCT07125833 |
| Cryoneurolysis | Other | Approved | Degenerative Joint Disease of Shoulder | RECRUITING | NCT07125833 |
| Local Infiltration Analgesia (LIA) of EXPAREL | Other | Approved | Total Knee Arthroplasty | RECRUITING | NCT06946368 |
| Adductor Canal Block (ACB) and Local Local Infiltration Analgesia of EXPAREL | Other | Approved | Total Knee Arthroplasty | RECRUITING | NCT06946368 |
| Intra-articular Posteromedial Surgeon Administered (IPSA) Block of EXPAREL | Other | Approved | Total Knee Arthroplasty | RECRUITING | NCT06946368 |
| an open surgery for abdominal hernia repair | Procedure | Phase PHASE4 | Pain | COMPLETED | NCT02128646 |
| laparoscopic abdominal hernia repair | Other | Phase PHASE4 | Pain | COMPLETED | NCT02128646 |
| Ketorolac | Other | Phase PHASE4 | Pain | COMPLETED | NCT02128646 |
| EXPAREL | Other | Phase PHASE4 | Pain | COMPLETED | NCT02128646 |
| Thoracic epidural analgesia | Other | Phase PHASE4 | Laparotomy | COMPLETED | NCT03827291 |
| Exparel | Other | Phase PHASE4 | Laparotomy | COMPLETED | NCT03827291 |
| Continuous popliteal nerve block with unencapsulated bupivacaine | Other | Phase PHASE4 | Moderate-to-severely Painful Ankle Surgery | ENROLLING_BY_INVITATION | NCT06995352 |
| Adductor canal nerve block with exclusively unencapsulated bupivacaine | Other | Phase PHASE4 | Moderate-to-severely Painful Ankle Surgery | ENROLLING_BY_INVITATION | NCT06995352 |
| Popliteal nerve block with exclusively unencapsulated bupivacaine | Other | Phase PHASE4 | Moderate-to-severely Painful Ankle Surgery | ENROLLING_BY_INVITATION | NCT06995352 |
| Continuous popliteal nerve block with normal saline | Other | Phase PHASE4 | Moderate-to-severely Painful Ankle Surgery | ENROLLING_BY_INVITATION | NCT06995352 |
| Adductor canal nerve block including liposomal bupivacaine | Other | Phase PHASE4 | Moderate-to-severely Painful Ankle Surgery | ENROLLING_BY_INVITATION | NCT06995352 |
| Popliteal nerve block including liposomal bupivacaine | Other | Phase PHASE4 | Moderate-to-severely Painful Ankle Surgery | ENROLLING_BY_INVITATION | NCT06995352 |
| Placebo | Other | Phase PHASE3 | Glenohumeral Osteoarthritis | RECRUITING | NCT06269705 |
| ZILRETTA | Other | Phase PHASE3 | Glenohumeral Osteoarthritis | RECRUITING | NCT06269705 |
| Triamcinolone Acetonide | Other | Phase PHASE2 | Osteoarthritis of Hip | TERMINATED | NCT06977568 |
| Zilretta | Other | Phase PHASE2 | Osteoarthritis of Hip | TERMINATED | NCT06977568 |
| bupivacaine | Other | Phase PHASE1 | Postoperative Pain | RECRUITING | NCT06271265 |
| EXPAREL | Other | Phase PHASE1 | Postoperative Pain | RECRUITING | NCT06271265 |
| Treatment for Knee OA | Drug | Preclinical | Knee Osteoarthritis | RECRUITING | NCT05495334 |
| Bupivacaine Hydrochloride | Other | Phase PHASE2 | Pain, Postoperative | ENROLLING_BY_INVITATION | NCT06077422 |
| bupivacaine liposome injectable suspension | Other | Phase PHASE2 | Pain, Postoperative | ENROLLING_BY_INVITATION | NCT06077422 |
| 0.25% bupivacaine (HCl): 30 ml | Other | Phase PHASE3 | Total Ankle Arthroplasty | RECRUITING | NCT07212114 |
| 0.25% bupivacaine (HCl): 50 ml | Other | Phase PHASE3 | Total Ankle Arthroplasty | RECRUITING | NCT07212114 |
| EXPAREL | Other | Phase PHASE3 | Total Ankle Arthroplasty | RECRUITING | NCT07212114 |
| ioveraº system | Other | Preclinical | Pain Management Improvement | COMPLETED | NCT06093776 |
| Placebo | Other | Phase PHASE2 | Osteoarthritis (OA) of the Knee | ACTIVE_NOT_RECRUITING | NCT06884865 |
| Enekinragene Inzadenovec (PCRX-201) | Other | Phase PHASE2 | Osteoarthritis (OA) of the Knee | ACTIVE_NOT_RECRUITING | NCT06884865 |
| sham iovera° system treatment | Drug | Approved | Spasticity, Cerebral or Spinal Condition | RECRUITING | NCT06340451 |
| iovera° system | Other | Approved | Spasticity, Cerebral or Spinal Condition | RECRUITING | NCT06340451 |
| Best Practices | Other | Phase PHASE3 | Knee Osteoarthritis | COMPLETED | NCT04504812 |
| Pain Coping Skills Training | Other | Phase PHASE3 | Knee Osteoarthritis | COMPLETED | NCT04504812 |
| Nerve Procedure with nerve ablation | Procedure | Phase PHASE3 | Knee Osteoarthritis | COMPLETED | NCT04504812 |
| Nerve Procedure with long acting blocks | Procedure | Phase PHASE3 | Knee Osteoarthritis | COMPLETED | NCT04504812 |
| Intra-Articular Injection | Other | Phase PHASE3 | Knee Osteoarthritis | COMPLETED | NCT04504812 |
| Duloxetine | Other | Phase PHASE3 | Knee Osteoarthritis | COMPLETED | NCT04504812 |
| Cryoneurolysis | Other | Approved | Spasticity as Sequela of Stroke | RECRUITING | NCT06958289 |
| Radiofrequency ablation (RFA) | Other | Approved | Low Back Pain, Chronic | RECRUITING | NCT07214844 |
| Iovera Medial Branch Cryoneurolysis | Other | Approved | Low Back Pain, Chronic | RECRUITING | NCT07214844 |
| Radiofrequency ablation (RFA) | Other | Approved | Low Back Pain, Chronic | RECRUITING | NCT07214844 |
| Iovera Medial Branch Cryoneurolysis | Other | Approved | Low Back Pain, Chronic | RECRUITING | NCT07214844 |
| Radiofrequency ablation (RFA) | Other | Approved | Low Back Pain, Chronic | RECRUITING | NCT07214844 |
| Iovera Medial Branch Cryoneurolysis | Other | Approved | Low Back Pain, Chronic | RECRUITING | NCT07214844 |
| Radiofrequency ablation (RFA) | Other | Approved | Low Back Pain, Chronic | RECRUITING | NCT07214844 |
| Iovera Medial Branch Cryoneurolysis | Other | Approved | Low Back Pain, Chronic | RECRUITING | NCT07214844 |
| Radiofrequency ablation (RFA) | Other | Approved | Low Back Pain, Chronic | RECRUITING | NCT07214844 |
| Iovera Medial Branch Cryoneurolysis | Other | Approved | Low Back Pain, Chronic | RECRUITING | NCT07214844 |
| Radiofrequency ablation (RFA) | Other | Approved | Low Back Pain, Chronic | RECRUITING | NCT07214844 |
| Iovera Medial Branch Cryoneurolysis | Other | Approved | Low Back Pain, Chronic | RECRUITING | NCT07214844 |
| Radiofrequency ablation (RFA) | Other | Approved | Low Back Pain, Chronic | RECRUITING | NCT07214844 |
| Iovera Medial Branch Cryoneurolysis | Other | Approved | Low Back Pain, Chronic | RECRUITING | NCT07214844 |
| Radiofrequency ablation (RFA) | Other | Approved | Low Back Pain, Chronic | RECRUITING | NCT07214844 |
| Iovera Medial Branch Cryoneurolysis | Other | Approved | Low Back Pain, Chronic | RECRUITING | NCT07214844 |
| Radiofrequency ablation (RFA) | Other | Approved | Low Back Pain, Chronic | RECRUITING | NCT07214844 |
| Iovera Medial Branch Cryoneurolysis | Other | Approved | Low Back Pain, Chronic | RECRUITING | NCT07214844 |
| Radiofrequency ablation (RFA) | Other | Approved | Low Back Pain, Chronic | RECRUITING | NCT07214844 |
| Iovera Medial Branch Cryoneurolysis | Other | Approved | Low Back Pain, Chronic | RECRUITING | NCT07214844 |
| Radiofrequency ablation (RFA) | Other | Approved | Low Back Pain, Chronic | RECRUITING | NCT07214844 |
| Iovera Medial Branch Cryoneurolysis | Other | Approved | Low Back Pain, Chronic | RECRUITING | NCT07214844 |
| Cryoneurolysis | Other | Approved | Spasticity as Sequela of Stroke | RECRUITING | NCT06958289 |
| Cryoneurolysis | Other | Approved | Spasticity as Sequela of Stroke | RECRUITING | NCT06958289 |
| Cryoneurolysis | Other | Approved | Spasticity as Sequela of Stroke | RECRUITING | NCT06958289 |
| Cryoneurolysis | Other | Approved | Spasticity as Sequela of Stroke | RECRUITING | NCT06958289 |
| Cryoneurolysis | Other | Approved | Spasticity as Sequela of Stroke | RECRUITING | NCT06958289 |
| Cryoneurolysis | Other | Approved | Spasticity as Sequela of Stroke | RECRUITING | NCT06958289 |