SymbolOCUL
NameOCULAR THERAPEUTIX, INC
SectorHEALTH CARE
RegionNorth America
IndustryPharmaceutical Preparations
Address15 CROSBY DRIVE, BEDFORD, MA 01730
Telephone781-357-4000
Fax
Email
Websitehttps://www.ocutx.com
IncorporationUNDEFINED
Incorporated On
Employees
Fiscal Year
Public Since
ExchangesNASDAQ
Auditor
Audit StatusNOT PROVIDED
Reporting Status
CIK0001393434
Description

Ocular Therapeutix Inc is a biotechnology company that specializes in therapies for diseases and conditions of the eye. The company uses its proprietary hydrogel platform technology to deliver therapeutic agents to the eye. Its pipeline consists of eye medication that aims to overcome the limitations of current eye-drop-based therapies for ophthalmic diseases and conditions. Ocular Therapeutix aims to offer medication to replace the existing eye-drop therapy regimen, with the aim of lasting weeks or months with a one-time product application.

Additional info from NASDAQ:
Ocular Therapeutix Inc is a biotechnology company that specializes in therapies for diseases and conditions of the eye. The company uses its proprietary hydrogel platform technology to deliver therapeutic agents to the eye. Its pipeline consists of eye medication that aims to overcome the limitations of current eye-drop-based therapies for ophthalmic diseases and conditions. Ocular Therapeutix aims to offer medication to replace the existing eye-drop therapy regimen, with the aim of lasting weeks or months with a one-time product application.

2026-06-12 21:23

Director Warden Charles M 🟢 acquired 58.0K shares (1 derivative) of OCULAR THERAPEUTIX, INC (OCUL) at $8.74 Transaction Date: Jun 10, 2026 | Filing ID: 073589

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2026-06-12 21:22

Director Graves Adrienne L 🟢 acquired 58.0K shares (1 derivative) of OCULAR THERAPEUTIX, INC (OCUL) at $8.74 Transaction Date: Jun 10, 2026 | Filing ID: 073587

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2026-06-12 21:22

Robins Jason Shand 🟢 acquired 29.5K shares (1 derivative) of OCULAR THERAPEUTIX, INC (OCUL) at $8.74 Transaction Date: Jun 10, 2026 | Filing ID: 073586

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2026-06-12 21:21

Director Hong Seung Suh 🟢 acquired 58.0K shares (1 derivative) of OCULAR THERAPEUTIX, INC (OCUL) at $8.74 Transaction Date: Jun 10, 2026 | Filing ID: 073585

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2026-06-12 21:20

Director LINDSTROM RICHARD L MD 🟢 acquired 58.0K shares (1 derivative) of OCULAR THERAPEUTIX, INC (OCUL) at $8.74 Transaction Date: Jun 10, 2026 | Filing ID: 073584

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2026-06-12 21:19

Director RAINES MERILEE 🟢 acquired 58.0K shares (1 derivative) of OCULAR THERAPEUTIX, INC (OCUL) at $8.74 Transaction Date: Jun 10, 2026 | Filing ID: 073582

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2026-06-12 21:19

Director Williams Leslie J. 🟢 acquired 58.0K shares (1 derivative) of OCULAR THERAPEUTIX, INC (OCUL) at $8.74 Transaction Date: Jun 10, 2026 | Filing ID: 073580

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2026-06-12 20:23

(99% Neutral) OCULAR THERAPEUTIX, INC (OCUL) Announces New Board Appointment

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2026-06-05 20:01

Waheed Nadia 🔴 sold 14.8K shares of OCULAR THERAPEUTIX, INC (OCUL) at $8.27 Transaction Date: Jun 03, 2026 | Filing ID: 070956

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2026-06-05 11:00

Ocular Therapeutix™ Reports Inducement Grants Under Nasdaq Listing Rule 5635(c)(4)

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Trial ID Title Phase Indication Status Start Date Completion Date Source
NCT02309736 OTX-14-002: Device Exposure Registry Endophthalmitis Withdrawn ClinicalTrials.gov
NCT07516132 Study to Evaluate Long-Term Safety of Intravitreal OTX-TKI (Axitinib Implant) i… Phase3 Neovascular Age-Related Macular Degeneration (nAMD) Not_Yet_Recruiting 2026-04-01 2030-08-01 ClinicalTrials.gov
NCT07235085 A Study to Evaluate the Efficacy and Safety of OTX-TKI (Axitinib Implant) in Pa… Phase3 Non-Proliferative Diabetic Retinopathy Recruiting 2025-11-17 2027-03-01 ClinicalTrials.gov
NCT06495918 Study to Evaluate the Efficacy and Safety of Intravitreal OTX-TKI (Axitinib Imp… Phase3 Neovascular Age-related Macular Degeneration Active_Not_Recruiting 2024-11-27 2027-01-08 ClinicalTrials.gov
NCT06223958 Study to Evaluate the Efficacy and Safety of Intravitreal OTX-TKI (Ocular Thera… Phase3 Neovascular Age-Related Macular Degeneration Active_Not_Recruiting 2024-01-29 2027-09-27 ClinicalTrials.gov
NCT05814757 OTX-DED for the Short-term Treatment of the Symptoms of Dry Eye Disease (DED) Phase2 Dry Eye Syndromes Completed 2023-05-11 2024-05-22 ClinicalTrials.gov
NCT05695417 Study to Evaluate the Safety, Tolerability, and Efficacy of OTX-TKI in Subjects… Phase1 Non-proliferative Diabetic Retinopathy Unknown 2023-01-15 2024-12-01 ClinicalTrials.gov
NCT05372315 Efficacy of Dextenza Insert in Upper vs Lower Punctum Following Cataract Surger… Phase4 Cataract Completed 2022-06-15 2022-10-31 ClinicalTrials.gov
NCT05307081 An Observational, Qualitative Study Assessing Eye Drop Administration Ocular Injury Unknown 2022-04-21 2023-12-01 ClinicalTrials.gov
NCT05335122 A Study to Evaluate the Efficacy and Safety of OTX-TIC (Travoprost) Intracamera… Phase2 Open Angle Glaucoma Completed 2022-03-16 2025-01-24 ClinicalTrials.gov
NCT05143281 The SITE Study - Dexamethasone Ophthalmic Insert In OR on Day of Surgery Versus… Phase4 Cataract Completed 2021-12-13 2023-02-01 ClinicalTrials.gov
NCT05116345 DEXTENZA for the Treatment of Pain and Inflammation Following Surgical Trabecul… Phase4 Glaucoma Following Surgery Unknown 2021-11-01 2023-11-01 ClinicalTrials.gov
NCT04728646 Evaluation of Dextenza in Patients With Ocular GVHD and Effects on Ocular Surfa… Phase4 Graft Vs Host Disease Withdrawn 2021-09-01 2021-12-13 ClinicalTrials.gov
NCT05023304 In Clinic Optometrist Insertion of Dextenza Prior to Cataract Surgery Phase4 Cataract Completed 2021-08-23 2022-10-01 ClinicalTrials.gov
NCT04989699 Study Evaluating the Treatment of OTX-TKI for Subjects With Neovascular Age-rel… Phase1 Neovascular Age-Related Macular Degeneration Completed 2021-07-28 2023-12-18 ClinicalTrials.gov
NCT04945824 A Human Factors Study to Evaluate a Novel Intracanalicular Insertion Device in … Early_Phase1 Healthy Terminated 2021-06-01 2022-11-01 ClinicalTrials.gov
NCT04708821 DEXTENZA Therapy for Treatment of Allergic Conjunctivitis Phase4 Bilateral Conjunctivitis (Disorder) Completed 2021-04-30 2021-09-02 ClinicalTrials.gov
NCT04863742 Evaluation Of Vision Recovery And Comfort Index In Patients With Borderline/Mil… Phase4 Dry Eye Syndromes Unknown 2021-04-26 2021-09-30 ClinicalTrials.gov
NCT04529512 INtravitreal and Aqueous Dexamethasone Levels After DEXtenza Phase4 Ocular Disease Requiring Surgery Unknown 2021-03-01 2021-03-01 ClinicalTrials.gov
NCT04747977 To Assess the Efficacy and Safety of OTX-DED for the Short-term Treatment of Si… Phase2 Dry Eye Completed 2021-02-12 2021-09-22 ClinicalTrials.gov
NCT04530864 Pre-Surgical Ocular Surface Treatment With Intracanalicular Dexamethasone Inser… Phase4 Dry Eye Disease Unknown 2021-01-01 2021-07-01 ClinicalTrials.gov
NCT04563299 Effect on Pain and Inflammation With DEXTENZA Treatment in Patients Undergoing … Phase4 Neovascular Age-related Macular Degeneration Terminated 2020-12-09 2023-02-14 ClinicalTrials.gov
NCT04687800 Clinical Investigation of the Dextenza 0.4mg Intracanalicular Insert Delivery S… Phase4 Cataract Terminated 2020-12-01 2022-10-24 ClinicalTrials.gov
NCT04563559 PREFERENTIAL Study Phase2 Cataract Surgery Withdrawn 2020-11-01 2021-11-01 ClinicalTrials.gov
NCT04403516 Dextenza in Pterygium Surgery Phase4 Pterygium Completed 2020-10-01 2021-08-05 ClinicalTrials.gov
NCT04539548 A Study Assessing the Safety and Efficacy of Dextenza® for the Treatment of Ocu… Phase3 Cataract Completed 2020-09-04 2023-12-21 ClinicalTrials.gov
NCT04527887 Intracanalicular Dexamethasone Insert for the Treatment of Inflammation and Dis… Phase4 Dry Eye Terminated 2020-09-04 2024-12-31 ClinicalTrials.gov
NCT04413253 Xiidra vs. Xiidra + Dextenza Treatment for Dry Eye Disease Phase4 Dry Eye Syndromes Terminated 2020-08-01 2022-04-11 ClinicalTrials.gov
NCT04413279 Lipiflow Treatment Alone vs. Lipiflow + Dextenza Treatment for Dry Eye Disease Phase4 Dry Eye Syndromes Completed 2020-08-01 2021-07-01 ClinicalTrials.gov
NCT04464629 Assessing the Efficacy and Safety of DEXTENZA in Pseudo Phakic Patients Undergo… Phase4 Retinal Detachment Terminated 2020-07-14 2023-01-25 ClinicalTrials.gov
NCT04426734 Evaluation of DEXTENZA in the Management of Pain and Inflammation in Patients W… Phase4 Non-infectious Anterior Uveitis Unknown 2020-07-01 2021-03-31 ClinicalTrials.gov
NCT04396990 The RESTORE Study, A Randomized, Controlled, Masked (Reading Center) Prospectiv… Phase4 Refractive Surgery Completed 2020-06-08 2020-09-28 ClinicalTrials.gov
NCT04371445 Dextenza in the Post-op Management of Vitreoretinal Surgeries Phase4 Vitreoretinal Surgery Recruiting 2020-06-01 2026-05-01 ClinicalTrials.gov
NCT04362670 Study to Evaluate the Safety, Tolerability, and Efficacy of OTX-CSI in Subjects… Phase1 Dry Eye Disease Completed 2020-04-23 2021-08-11 ClinicalTrials.gov
NCT04168112 Intracanalicular Dexamethasone Insert for Post-Corneal Cross-Linking Inflammati… Phase4 Keratoconus, Unstable Completed 2020-02-12 2023-04-05 ClinicalTrials.gov
NCT04200651 Prospective Study on DEXTENZA® Safety And Efficacy Following Concomitant MIGS a… Phase4 Glaucoma Terminated 2020-01-13 2023-07-12 ClinicalTrials.gov
NCT04462523 DEXTENZA for the Treatment of Postoperative Pain and Inflammation Following Vit… Phase4 Vitreo-Retinal Surgery Completed 2020-01-03 2022-03-31 ClinicalTrials.gov
NCT04316936 Omidria and Dexycu, or Omidria and Dextenza Compared to Topical Prednisolone Ac… Phase4 Cataract Surgery Completed 2019-12-10 2020-12-23 ClinicalTrials.gov
NCT04205916 A Trial Evaluating Patient Preference of Dropless vs Drops Post Cataract Surgery Phase4 Patient Preference Recruiting 2019-11-04 2020-12-01 ClinicalTrials.gov
NCT04050865 A Study Evaluating the Safety and Efficacy of OTX-DP for the Treatment of Aller… Phase3 Allergic Conjunctivitis Completed 2019-08-05 2020-02-28 ClinicalTrials.gov
NCT03630315 CLN-0046: Treatment of AMD Subjects With OTX-TKI Phase1 Neovascular Age-related Macular Degeneration Completed 2019-02-18 2024-01-10 ClinicalTrials.gov
NCT04061044 A Study to Evaluate the Long Term Safety of OTX-TP (Sustained Release Travopros… Phase3 Open Angle Glaucoma and Ocular Hypertension Completed 2018-07-10 2020-09-22 ClinicalTrials.gov
NCT04360174 CLN-0045: Safety, and Efficacy of OTX-TIC in Participants With Open Angle Glauc… Phase1 Ocular Hypertension Completed 2018-04-25 2021-05-24 ClinicalTrials.gov
NCT02914509 Phase 3 Study Evaluating Safety and Efficacy of OTX-TP in Subjects With OAG or … Phase3 Open Angle Glaucoma Completed 2016-11-07 2019-03-30 ClinicalTrials.gov
NCT02736175 OTX-15:003: A Phase 3 Study Evaluating the Safety and Efficacy of OTX-DP for th… Phase3 Post-Surgical Ocular Pain Completed 2015-10-01 2016-07-01 ClinicalTrials.gov
NCT02988882 OTX-15-002: A Phase 3 Study Evaluating the Safety and Efficacy of OTX-DP for th… Phase3 Chronic Allergic Conjunctivitis Completed 2015-06-01 2016-04-27 ClinicalTrials.gov
NCT02445326 OTX-14-007: A Phase 3 Study Evaluating the Safety and Efficacy of OTX-DP for th… Phase3 Chronic Allergic Conjunctivitis Completed 2015-04-01 2015-09-01 ClinicalTrials.gov
NCT02468700 OTX-14-006: A Phase 2 Study Evaluating the Safety and Efficacy of OTX-DP for th… Phase2 Dry Eye Completed 2015-01-01 2015-11-01 ClinicalTrials.gov
NCT02310815 ReSure Sealant Post Approval Study Adverse Events Completed 2014-12-01 2016-04-01 ClinicalTrials.gov
NCT02312544 Phase 2b Study Evaluating Safety and Efficacy of OTX-TP Compared to Timolol Dro… Phase2 Glaucoma Completed 2014-11-01 2015-12-01 ClinicalTrials.gov
NCT02089113 OTX-14-003: A Phase 3 Study Evaluating the Safety and Efficacy of OTX-DP for th… Phase3 Post-Surgical Ocular Pain Completed 2014-04-01 2015-03-01 ClinicalTrials.gov
NCT02062905 OTX-14-001: A Phase 2 Study Evaluating the Safety and Efficacy of OTX-DP for th… Phase2 Chronic Allergic Conjunctivitis Completed 2014-03-01 2014-11-01 ClinicalTrials.gov
NCT02034019 Phase 3 Study Evaluating Safety and Efficacy of OTX-DP for Treatment of Ocular … Phase3 Post Ocular Surgical Inflammation and Pain Completed 2014-02-01 2015-02-01 ClinicalTrials.gov
NCT01845038 Multi-Arm Feasibility Study Evaluating OTX-TP Compared to Timolol in Treatment … Phase1 Glaucoma Completed 2013-04-01 2014-05-01 ClinicalTrials.gov
NCT01800175 Non-Significant Risk Feasibility Study to Assess Retention and Replacement of t… Phase1 Healthy Subjects Unknown 2013-02-01 ClinicalTrials.gov
NCT01666210 Phase II Study Evaluating Safety/Efficacy of OTX-DP for Treatment of Ocular Inf… Phase2 Ocular Inflammation and Pain Completed 2012-10-01 2013-08-01 ClinicalTrials.gov
NCT01498224 ReSure Sealant Pivotal Study Phase3 Cataract Surgery Incision Leak Completed 2011-12-01 2012-11-01 ClinicalTrials.gov
NCT00774228 I-ZIP Ocular Bandage Pivotal Study Na Cataract Completed 2008-10-01 2009-08-01 ClinicalTrials.gov
Total clinical trials: 58
Product Name Type Development Stage Therapeutic Area Study Status Trial ID
ReSure Sealant Other Preclinical Adverse Events COMPLETED NCT02310815
Timolol Other Phase PHASE2 Glaucoma COMPLETED NCT02312544
OTX-TP Other Phase PHASE2 Glaucoma COMPLETED NCT02312544
Placebo Vehicle Other Phase PHASE3 Post-Surgical Ocular Pain COMPLETED NCT02736175
Dexamethasone Other Phase PHASE3 Post-Surgical Ocular Pain COMPLETED NCT02736175
Punctum Plug Other Phase PHASE3 Post Ocular Surgical Inflammation and Pain COMPLETED NCT02034019
Dexamethasone Other Phase PHASE3 Post Ocular Surgical Inflammation and Pain COMPLETED NCT02034019
Dexamethasone Intracanalicular Insert, 0.4mg with LipiFlow Thermal Pulsation Other Phase PHASE4 Dry Eye Syndromes COMPLETED NCT04413279
LipiFlow Thermal Pulsation Other Phase PHASE4 Dry Eye Syndromes COMPLETED NCT04413279
Dexamethasone Intracanalicular Insert, 0.4mg with Lifitegrast 5% Ophthalmic Solution Other Phase PHASE4 Dry Eye Syndromes TERMINATED NCT04413253
Lifitegrast 5% Ophthalmic Solution Other Phase PHASE4 Dry Eye Syndromes TERMINATED NCT04413253
Artificial Tears Other Preclinical Ocular Injury UNKNOWN NCT05307081
Punctum Plug Other Phase PHASE1 Healthy Subjects UNKNOWN NCT01800175
Timolol Maleate (0.5%) dosed twice daily with punctum plug without drug Drug Phase PHASE1 Glaucoma COMPLETED NCT01845038
OTX-TPb ~3µg/day over 3 months with natural tears drops Other Phase PHASE1 Glaucoma COMPLETED NCT01845038
OTX-TPa ~4µg/day over 2 mos. with natural tears drops Other Phase PHASE1 Glaucoma COMPLETED NCT01845038
Sutures Other Phase PHASE3 Cataract Surgery Incision Leak COMPLETED NCT01498224
ReSure Sealant Other Phase PHASE3 Cataract Surgery Incision Leak COMPLETED NCT01498224
Placebo Vehicle Other Phase PHASE2 Dry Eye COMPLETED NCT02468700
Dexamethasone Other Phase PHASE2 Dry Eye COMPLETED NCT02468700
Placebo Vehicle Other Phase PHASE3 Chronic Allergic Conjunctivitis COMPLETED NCT02445326
Dexamethasone Other Phase PHASE3 Chronic Allergic Conjunctivitis COMPLETED NCT02445326
Placebo Vehicle Other Phase PHASE2 Chronic Allergic Conjunctivitis COMPLETED NCT02062905
Dexamethasone Other Phase PHASE2 Chronic Allergic Conjunctivitis COMPLETED NCT02062905
Placebo Vehicle Other Phase PHASE3 Post-Surgical Ocular Pain COMPLETED NCT02089113
Dexamethasone Other Phase PHASE3 Post-Surgical Ocular Pain COMPLETED NCT02089113
Standard of care surgery Procedure Phase PHASE4 Patient Preference RECRUITING NCT04205916
Dexamethasone Other Phase PHASE4 Patient Preference RECRUITING NCT04205916
ReSure Sealant Other Preclinical Endophthalmitis WITHDRAWN NCT02309736
Topical Prednisolone Acetate 1% Other Phase PHASE4 Non-infectious Anterior Uveitis UNKNOWN NCT04426734
Dextenza Dexamethasone Implant Other Phase PHASE4 Non-infectious Anterior Uveitis UNKNOWN NCT04426734
Placebo Vehicle Other Phase PHASE3 Chronic Allergic Conjunctivitis COMPLETED NCT02988882
Dexamethasone Other Phase PHASE3 Chronic Allergic Conjunctivitis COMPLETED NCT02988882
Dextenza 0.4Mg Ophthalmic Insert Other Phase PHASE4 Dry Eye Disease UNKNOWN NCT04530864
DEXTENZA® Other Phase PHASE4 Ocular Disease Requiring Surgery UNKNOWN NCT04529512
Prednisolone Acetate Other Phase PHASE4 Dry Eye Syndromes UNKNOWN NCT04863742
Dextenza 0.4Mg Ophthalmic Insert Other Phase PHASE4 Dry Eye Syndromes UNKNOWN NCT04863742
Placebo plug with no drug Drug Phase PHASE3 Allergic Conjunctivitis COMPLETED NCT04050865
Dexamethasone, 0.4mg Other Phase PHASE3 Allergic Conjunctivitis COMPLETED NCT04050865
Placebo Vehicle Other Phase PHASE3 Open Angle Glaucoma COMPLETED NCT02914509
Travoprost Other Phase PHASE3 Open Angle Glaucoma COMPLETED NCT02914509
Placebo Vehicle Punctum Plug Other Phase PHASE2 Ocular Inflammation and Pain COMPLETED NCT01666210
OTX-DP (Dexamethasone punctum plug) Other Phase PHASE2 Ocular Inflammation and Pain COMPLETED NCT01666210
Topical Dexamethasone Other Phase PHASE4 Glaucoma Following Surgery UNKNOWN NCT05116345
DEXTENZA Other Phase PHASE4 Glaucoma Following Surgery UNKNOWN NCT05116345
Prednisolone Acetate 1% Ophthalmic Suspension [PRED FORTE] Other Phase PHASE2 Cataract Surgery WITHDRAWN NCT04563559
Dextenza 0.4Mg Ophthalmic Insert Other Phase PHASE2 Cataract Surgery WITHDRAWN NCT04563559
Regular dissolvable intracanalicular plug Other Phase PHASE4 Graft Vs Host Disease WITHDRAWN NCT04728646
DEXTENZA (dexamethasone ophthalmic insert) 0.4 mg, for intracanalicular use Other Phase PHASE4 Graft Vs Host Disease WITHDRAWN NCT04728646
Prednisolone Acetate 1% Other Phase PHASE4 Pterygium COMPLETED NCT04403516
Dexamethasone Intracanalicular Insert, 0.4mg Other Phase PHASE4 Pterygium COMPLETED NCT04403516
olopatadine hydrochloride ophthalmic solution 0.7% Other Phase PHASE4 Bilateral Conjunctivitis (Disorder) COMPLETED NCT04708821
0.2% loteprednol etabonate ophthalmic suspension Other Phase PHASE4 Bilateral Conjunctivitis (Disorder) COMPLETED NCT04708821
Dexamethasone ophthalmic insert 0.4Mg Other Phase PHASE4 Bilateral Conjunctivitis (Disorder) COMPLETED NCT04708821
Durezol 0.05% Ophthalmic Emulsion Other Phase PHASE4 Cataract TERMINATED NCT04687800
Dextenza 0.4mg intracanalicular Insert Other Phase PHASE4 Cataract TERMINATED NCT04687800
Dilator Other Phase EARLY_PHASE1 Healthy TERMINATED NCT04945824
Dexamethasone Ophthalmic Other Phase EARLY_PHASE1 Healthy TERMINATED NCT04945824
OTX-DED Other Phase PHASE2 Dry Eye COMPLETED NCT04747977
Prednisolone Acetate Other Phase PHASE4 Neovascular Age-related Macular Degeneration TERMINATED NCT04563299
Dextenza 0.4Mg Ophthalmic Insert Other Phase PHASE4 Neovascular Age-related Macular Degeneration TERMINATED NCT04563299
Ophthalmic Insert Other Phase PHASE3 Open Angle Glaucoma and Ocular Hypertension COMPLETED NCT04061044
Topical Prednisolone Other Phase PHASE4 Vitreo-Retinal Surgery COMPLETED NCT04462523
Dextenza 0.4Mg Ophthalmic Insert Other Phase PHASE4 Vitreo-Retinal Surgery COMPLETED NCT04462523
Prednisolone Acetate 1% Other Phase PHASE4 Cataract Surgery COMPLETED NCT04316936
Dexycu, 9% Intraocular Suspension Other Phase PHASE4 Cataract Surgery COMPLETED NCT04316936
Dextenza (dexamethasone ophthalmic insert) 0.4mg Other Phase PHASE4 Cataract Surgery COMPLETED NCT04316936
Omidria Other Phase PHASE4 Cataract Surgery COMPLETED NCT04316936
Dexamethasone 0.4 MG [Dextenza] Other Phase PHASE4 Cataract COMPLETED NCT05143281
Prednisolone Acetate Other Phase PHASE4 Retinal Detachment TERMINATED NCT04464629
Dextenza Other Phase PHASE4 Retinal Detachment TERMINATED NCT04464629
Dextenza 0.4Mg Ophthalmic Insert Other Phase PHASE4 Cataract COMPLETED NCT05372315
Placebo Vehicle Other Phase PHASE1 Dry Eye Disease COMPLETED NCT04362670
OTX-CSI Other Phase PHASE1 Dry Eye Disease COMPLETED NCT04362670
Sham Other Phase PHASE1 Non-proliferative Diabetic Retinopathy UNKNOWN NCT05695417
OTX-TKI Other Phase PHASE1 Non-proliferative Diabetic Retinopathy UNKNOWN NCT05695417
Aflibercept/Sham Other Phase PHASE1 Neovascular Age-Related Macular Degeneration COMPLETED NCT04989699
OTX-TKI/Sham Other Phase PHASE1 Neovascular Age-Related Macular Degeneration COMPLETED NCT04989699
Prednisolone Acetate Other Phase PHASE4 Keratoconus, Unstable COMPLETED NCT04168112
Dextenza Other Phase PHASE4 Keratoconus, Unstable COMPLETED NCT04168112
Prednisolone Acetate 1% Oph Susp Other Phase PHASE4 Glaucoma TERMINATED NCT04200651
Dexamethasone Ophthalmic Insert Other Phase PHASE4 Glaucoma TERMINATED NCT04200651
Prednisolone acetate ophthalmic suspension USP 1% Other Phase PHASE3 Cataract COMPLETED NCT04539548
Dextenza Ophthalmic Insert Other Phase PHASE3 Cataract COMPLETED NCT04539548
Collagen Punctal Plug Other Phase PHASE2 Dry Eye Syndromes COMPLETED NCT05814757
Controlled Insertion Other Phase PHASE2 Dry Eye Syndromes COMPLETED NCT05814757
OTX-DED Other Phase PHASE2 Dry Eye Syndromes COMPLETED NCT05814757
Anti-VEGF Other Phase PHASE1 Neovascular Age-related Macular Degeneration COMPLETED NCT03630315
OTX-TKI Other Phase PHASE1 Neovascular Age-related Macular Degeneration COMPLETED NCT03630315
Topical Prednisolone Other Phase PHASE4 Refractive Surgery COMPLETED NCT04396990
Dextenza 0.4Mg Ophthalmic Insert Other Phase PHASE4 Refractive Surgery COMPLETED NCT04396990
OTX-TIC Other Phase PHASE1 Ocular Hypertension COMPLETED NCT04360174
ProLong™ collagen plugs Other Phase PHASE4 Dry Eye TERMINATED NCT04527887
Dextenza (IDI) (Sustained Release Dexamethasone), (0.4 mg) Other Phase PHASE4 Dry Eye TERMINATED NCT04527887
Durysta, Bimatoprost Intracameral Implant 10 µg Other Phase PHASE2 Open Angle Glaucoma COMPLETED NCT05335122
OTX-TIC high dose Travoprost Intracameral Implant Other Phase PHASE2 Open Angle Glaucoma COMPLETED NCT05335122
OTX-TIC low dose Travoprost Intracameral Implant Other Phase PHASE2 Open Angle Glaucoma COMPLETED NCT05335122
Aflibercept Other Phase PHASE3 Neovascular Age-Related Macular Degeneration ACTIVE_NOT_RECRUITING NCT06223958
OTX-TKI (axitinib implant) Other Phase PHASE3 Neovascular Age-Related Macular Degeneration ACTIVE_NOT_RECRUITING NCT06223958
Aflibercept Other Phase PHASE3 Neovascular Age-related Macular Degeneration ACTIVE_NOT_RECRUITING NCT06495918
OTX-TKI Other Phase PHASE3 Neovascular Age-related Macular Degeneration ACTIVE_NOT_RECRUITING NCT06495918
Topical prednisolone acetate Other Phase PHASE4 Cataract COMPLETED NCT05023304
Dextenza 0.4Mg Ophthalmic Insert Other Phase PHASE4 Cataract COMPLETED NCT05023304
Prednisolone Acetate 1% Oph Susp Other Phase PHASE4 Vitreoretinal Surgery RECRUITING NCT04371445
Dexamethasone Ophthalmic Insert Other Phase PHASE4 Vitreoretinal Surgery RECRUITING NCT04371445
Sham/mock procedure of intravitreal injection followed by a second sham/mock procedure at Week 24 Procedure Phase PHASE3 Non-Proliferative Diabetic Retinopathy RECRUITING NCT07235085
Intravitreal injection of axitinib hydrogel implant followed by a second intravitreal injection of the axitinib implant at Week 24 Other Phase PHASE3 Non-Proliferative Diabetic Retinopathy RECRUITING NCT07235085
Single intravitreal injection of axitinib hydrogel implant followed by a mock (sham) injection procedure at Week 24 Procedure Phase PHASE3 Non-Proliferative Diabetic Retinopathy RECRUITING NCT07235085
OTX-TKI Other Phase PHASE3 Neovascular Age-Related Macular Degeneration (nAMD) NOT_YET_RECRUITING NCT07516132
Sham/mock procedure of intravitreal injection followed by a second sham/mock procedure at Week 24 OTHER Phase PHASE3 Non-Proliferative Diabetic Retinopathy RECRUITING NCT07235085
Intravitreal injection of axitinib hydrogel implant followed by a second intravitreal injection of the axitinib implant at Week 24 DRUG Phase PHASE3 Non-Proliferative Diabetic Retinopathy RECRUITING NCT07235085
Single intravitreal injection of axitinib hydrogel implant followed by a mock (sham) injection procedure at Week 24 DRUG Phase PHASE3 Non-Proliferative Diabetic Retinopathy RECRUITING NCT07235085
Aflibercept DRUG Phase PHASE3 Neovascular Age-related Macular Degeneration ACTIVE_NOT_RECRUITING NCT06495918
OTX-TKI (axitinib implant) DRUG Phase PHASE3 Neovascular Age-Related Macular Degeneration ACTIVE_NOT_RECRUITING NCT06223958
Collagen Punctal Plug DRUG Phase PHASE2 Dry Eye Syndromes COMPLETED NCT05814757
Controlled Insertion DRUG Phase PHASE2 Dry Eye Syndromes COMPLETED NCT05814757
Sham DRUG Phase PHASE1 Non-proliferative Diabetic Retinopathy ACTIVE_NOT_RECRUITING NCT05695417
Durysta, Bimatoprost Intracameral Implant 10 µg DRUG Phase PHASE2 Open Angle Glaucoma COMPLETED NCT05335122
OTX-TIC high dose Travoprost Intracameral Implant DRUG Phase PHASE2 Open Angle Glaucoma COMPLETED NCT05335122
OTX-TIC low dose Travoprost Intracameral Implant DRUG Phase PHASE2 Open Angle Glaucoma COMPLETED NCT05335122
Artificial Tears DRUG Preclinical Ocular Injury UNKNOWN NCT05307081
Dexamethasone 0.4 MG [Dextenza] DRUG Phase PHASE4 Cataract COMPLETED NCT05143281
Topical Dexamethasone DRUG Phase PHASE4 Glaucoma Following Surgery UNKNOWN NCT05116345
DEXTENZA DRUG Phase PHASE4 Glaucoma Following Surgery UNKNOWN NCT05116345
Topical prednisolone acetate DRUG Phase PHASE4 Cataract COMPLETED NCT05023304
Aflibercept/Sham DRUG Phase PHASE1 Neovascular Age-Related Macular Degeneration COMPLETED NCT04989699
OTX-TKI/Sham DRUG Phase PHASE1 Neovascular Age-Related Macular Degeneration COMPLETED NCT04989699
Dilator DEVICE Phase EARLY_PHASE1 Healthy TERMINATED NCT04945824
Dexamethasone Ophthalmic DRUG Phase EARLY_PHASE1 Healthy TERMINATED NCT04945824
OTX-DED DRUG Phase PHASE2 Dry Eye Syndromes COMPLETED NCT05814757
Regular dissolvable intracanalicular plug DEVICE Phase PHASE4 Graft Vs Host Disease WITHDRAWN NCT04728646
DEXTENZA (dexamethasone ophthalmic insert) 0.4 mg, for intracanalicular use DRUG Phase PHASE4 Graft Vs Host Disease WITHDRAWN NCT04728646
olopatadine hydrochloride ophthalmic solution 0.7% DRUG Phase PHASE4 Bilateral Conjunctivitis (Disorder) COMPLETED NCT04708821
0.2% loteprednol etabonate ophthalmic suspension DRUG Phase PHASE4 Bilateral Conjunctivitis (Disorder) COMPLETED NCT04708821
Dexamethasone ophthalmic insert 0.4Mg DRUG Phase PHASE4 Bilateral Conjunctivitis (Disorder) COMPLETED NCT04708821
Durezol 0.05% Ophthalmic Emulsion DRUG Phase PHASE4 Cataract TERMINATED NCT04687800
Dextenza 0.4mg intracanalicular Insert DRUG Phase PHASE4 Cataract TERMINATED NCT04687800
Prednisolone Acetate 1% Ophthalmic Suspension [PRED FORTE] DRUG Phase PHASE2 Cataract Surgery WITHDRAWN NCT04563559
Prednisolone acetate ophthalmic suspension USP 1% DRUG Phase PHASE3 Cataract COMPLETED NCT04539548
Dextenza Ophthalmic Insert DRUG Phase PHASE3 Cataract COMPLETED NCT04539548
DEXTENZA® DRUG Phase PHASE4 Ocular Disease Requiring Surgery UNKNOWN NCT04529512
ProLong™ collagen plugs OTHER Phase PHASE4 Dry Eye TERMINATED NCT04527887
Dextenza (IDI) (Sustained Release Dexamethasone), (0.4 mg) DRUG Phase PHASE4 Dry Eye TERMINATED NCT04527887
Topical Prednisolone Acetate 1% DRUG Phase PHASE4 Non-infectious Anterior Uveitis UNKNOWN NCT04426734
Dextenza Dexamethasone Implant DEVICE Phase PHASE4 Non-infectious Anterior Uveitis UNKNOWN NCT04426734
Dexamethasone Intracanalicular Insert, 0.4mg with LipiFlow Thermal Pulsation DRUG Phase PHASE4 Dry Eye Syndromes COMPLETED NCT04413279
LipiFlow Thermal Pulsation PROCEDURE Phase PHASE4 Dry Eye Syndromes COMPLETED NCT04413279
Dexamethasone Intracanalicular Insert, 0.4mg with Lifitegrast 5% Ophthalmic Solution DRUG Phase PHASE4 Dry Eye Syndromes TERMINATED NCT04413253
Lifitegrast 5% Ophthalmic Solution DRUG Phase PHASE4 Dry Eye Syndromes TERMINATED NCT04413253
Dexamethasone Intracanalicular Insert, 0.4mg DRUG Phase PHASE4 Pterygium COMPLETED NCT04403516
Topical Prednisolone DRUG Phase PHASE4 Vitreo-Retinal Surgery COMPLETED NCT04462523
Dextenza 0.4Mg Ophthalmic Insert DRUG Phase PHASE4 Cataract COMPLETED NCT05372315
OTX-CSI DRUG Phase PHASE1 Dry Eye Disease COMPLETED NCT04362670
OTX-TIC DRUG Phase PHASE1 Ocular Hypertension COMPLETED NCT04360174
Prednisolone Acetate 1% DRUG Phase PHASE4 Pterygium COMPLETED NCT04403516
Dexycu, 9% Intraocular Suspension DRUG Phase PHASE4 Cataract Surgery COMPLETED NCT04316936
Dextenza (dexamethasone ophthalmic insert) 0.4mg DRUG Phase PHASE4 Cataract Surgery COMPLETED NCT04316936
Omidria DRUG Phase PHASE4 Cataract Surgery COMPLETED NCT04316936
Standard of care surgery OTHER Phase PHASE4 Patient Preference RECRUITING NCT04205916
Prednisolone Acetate 1% Oph Susp DRUG Phase PHASE4 Vitreoretinal Surgery RECRUITING NCT04371445
Dexamethasone Ophthalmic Insert DRUG Phase PHASE4 Vitreoretinal Surgery RECRUITING NCT04371445
Prednisolone Acetate DRUG Phase PHASE4 Dry Eye Syndromes UNKNOWN NCT04863742
Dextenza DRUG Phase PHASE4 Retinal Detachment TERMINATED NCT04464629
Ophthalmic Insert DRUG Phase PHASE3 Open Angle Glaucoma and Ocular Hypertension COMPLETED NCT04061044
Placebo plug with no drug DEVICE Phase PHASE3 Allergic Conjunctivitis COMPLETED NCT04050865
Dexamethasone, 0.4mg DRUG Phase PHASE3 Allergic Conjunctivitis COMPLETED NCT04050865
Anti-VEGF DRUG Phase PHASE1 Neovascular Age-related Macular Degeneration COMPLETED NCT03630315
OTX-TKI DRUG Phase PHASE3 Neovascular Age-Related Macular Degeneration (nAMD) NOT_YET_RECRUITING NCT07516132
Travoprost DRUG Phase PHASE3 Open Angle Glaucoma COMPLETED NCT02914509
Timolol DRUG Phase PHASE2 Glaucoma COMPLETED NCT02312544
OTX-TP DRUG Phase PHASE2 Glaucoma COMPLETED NCT02312544
Placebo Vehicle Punctum Plug DRUG Phase PHASE2 Ocular Inflammation and Pain COMPLETED NCT01666210
OTX-DP (Dexamethasone punctum plug) DRUG Phase PHASE2 Ocular Inflammation and Pain COMPLETED NCT01666210
Placebo Vehicle OTHER Phase PHASE1 Dry Eye Disease COMPLETED NCT04362670
Dexamethasone DRUG Phase PHASE4 Patient Preference RECRUITING NCT04205916
Timolol Maleate (0.5%) dosed twice daily with punctum plug without drug DRUG Phase PHASE1 Glaucoma COMPLETED NCT01845038
OTX-TPb ~3µg/day over 3 months with natural tears drops DRUG Phase PHASE1 Glaucoma COMPLETED NCT01845038
OTX-TPa ~4µg/day over 2 mos. with natural tears drops DRUG Phase PHASE1 Glaucoma COMPLETED NCT01845038
Punctum Plug DRUG Phase PHASE3 Post Ocular Surgical Inflammation and Pain COMPLETED NCT02034019
Sutures PROCEDURE Phase PHASE3 Cataract Surgery Incision Leak COMPLETED NCT01498224
ReSure Sealant DEVICE Preclinical Adverse Events COMPLETED NCT02310815
Oasis 24 Hour Soft Shield Collagen Corneal Shield DEVICE Approved Cataract COMPLETED NCT00774228
I-ZIP Ocular Bandage DEVICE Approved Cataract COMPLETED NCT00774228
Total products: 183