SymbolKYTX
NameKYVERNA THERAPEUTICS, INC.
SectorHEALTH CARE
RegionNorth America
IndustryBiotechnology: Biological Products (No Diagnostic Substances)
Address5980 HORTON STREET,SUITE 550, EMERYVILLE, California, United States
Telephone+1 (510) 626-8331
Fax
Email
Websitehttps://www.kyvernatx.com
IncorporationUNDEFINED
Incorporated On
Employees
Fiscal Year
Public Since
ExchangesNASDAQ
Auditor
Audit StatusNOT PROVIDED
Reporting Status
CIK0001994702
Description

Kyverna Therapeutics is a cell therapy company engineering a new class of therapies for autoimmune and inflammatory diseases. The Kyverna therapeutic platform combines advanced T-cell engineering and synthetic biology technologies to suppress and eliminate the autoreactive immune cells at the origin of autoimmune and inflammatory diseases. Kyvernas pipeline includes next-generation chimeric antigen receptor T-cell (CAR T) therapies in both autologous and allogeneic formats with properties well suited for use in B cell-driven autoimmune diseases.

Additional info from NASDAQ:
Kyverna Therapeutics is a cell therapy company engineering a new class of therapies for autoimmune and inflammatory diseases. The Kyverna therapeutic platform combines advanced T-cell engineering and synthetic biology technologies to suppress and eliminate the autoreactive immune cells at the origin of autoimmune and inflammatory diseases. Kyvernas pipeline includes next-generation chimeric antigen receptor T-cell (CAR T) therapies in both autologous and allogeneic formats with properties well suited for use in B cell-driven autoimmune diseases.

2026-05-18 12:00

(80% Positive) KYVERNA THERAPEUTICS, INC. (KYTX) Provides Update on Kyverna for its transition to a commercial-stage organization

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2026-05-18 12:00

Kyverna Therapeutics Names Greg Martini as Chief Financial Officer

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2026-05-14 12:00

Kyverna Therapeutics to Present at Upcoming Investor Conferences

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2026-05-12 20:05

(30% Negative) KYVERNA THERAPEUTICS, INC. (KYTX) Reports Q2 2026 Financial Results

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2026-05-12 20:02

Kyverna Therapeutics Announces Initiation of Rolling SPS BLA Submission and Reports First Quarter 2026 Financial Results

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2026-05-06 20:30

Dac Nadia 🟢 acquired 300.0K shares (1 derivative) of Kyverna Therapeutics, Inc. (KYTX) at $9.00 ($2.7M) Transaction Date: May 04, 2026 | Filing ID: 209120

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2026-05-06 17:30

New Form 3 - Kyverna Therapeutics, Inc. <b>Filed:</b> 2026-05-06 <b>AccNo:</b> 0001193125-26-209119 <b>Size:</b> 13 KB

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2026-04-22 11:00

(90% Positive) KYVERNA THERAPEUTICS, INC. (KYTX) Announces Enrollment Update for management Due to Patient Enrollment Issues, Regulatory Process, Manufacturing Considerations, Safety Review, Efficacy Assessment

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2026-04-21 22:45

Kyverna Presents Registrational Trial Primary Analysis for Miv-cel in Stiff Person Syndrome Demonstrating Statistically Significant, Durable Clinical Benefit Across All Endpoints in an Oral, Late-Breaker Session at AAN Annual Meeting

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2026-04-20 12:00

(85% Positive) KYVERNA THERAPEUTICS, INC. (KYTX) Announces Enrollment Update for profile Due to Patient Enrollment Issues, Regulatory Process, Safety Review, Efficacy Assessment

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Trial ID Title Phase Indication Status Start Date Completion Date Source
NCT07403188 A Long-Term Follow-Up Study for Participants Previously Treated With KYV-101 Refractory Lupus Nephritis Recruiting 2025-11-24 2041-01-01 ClinicalTrials.gov
NCT06475495 Comparison of B-cell Depletion by Rituximab and Anti-CD 19 CAR-T Therapy in Pat… Phase1 Rheumatoid Arthritis Active_Not_Recruiting 2024-12-04 2027-06-01 ClinicalTrials.gov
NCT06588491 KYSA-8: A Study of Anti-CD19 Chimeric Antigen Receptor T-Cell (CD19 CAR T) Ther… Phase2 Stiff-Person Syndrome Active_Not_Recruiting 2024-09-25 2026-12-01 ClinicalTrials.gov
NCT06384976 KYSA-7: A Study of Anti-CD19 CAR T-Cell Therapy, in Subjects With Refractory Pr… Phase2 Multiple Sclerosis, Primary Progressive Active_Not_Recruiting 2024-09-20 2029-01-01 ClinicalTrials.gov
NCT06193889 KYSA-6: A Study of Anti-CD19 Chimeric Antigen Receptor T-Cell Therapy, in Patie… Phase2 Myasthenia Gravis Recruiting 2024-08-28 2028-09-01 ClinicalTrials.gov
NCT06400303 KYSA-5: A Study of Anti-CD19 Chimeric Antigen Receptor T-Cell (CD19 CAR T) Ther… Phase1 Systemic Sclerosis Active_Not_Recruiting 2024-08-06 2027-03-01 ClinicalTrials.gov
NCT06451159 A Study of KYV-101, a CD19 CAR T Cell Therapy, in Participants With Treatment R… Phase1 Progressive Multiple Sclerosis Active_Not_Recruiting 2024-06-20 2027-02-01 ClinicalTrials.gov
NCT06138132 A Study of Anti-CD19 Chimeric Antigen Receptor T-Cell ( CAR-T) Therapy in Subje… Phase1 Multiple Sclerosis Recruiting 2024-04-10 2027-06-01 ClinicalTrials.gov
NCT05938725 KYSA-1: A Study of Anti-CD19 Chimeric Antigen Receptor T-Cell (CD19 CAR T) Ther… Phase1 Lupus Nephritis Active_Not_Recruiting 2023-04-28 2027-08-01 ClinicalTrials.gov
NCT06342960 KYSA-3: A Study of Anti-CD19 Chimeric Antigen Receptor T-Cell (CD19 CAR T) Ther… Phase1 Lupus Nephritis Active_Not_Recruiting 2022-12-01 2029-01-01 ClinicalTrials.gov
Total clinical trials: 10
Product Name Type Development Stage Therapeutic Area Study Status Trial ID
KYV-101 Other Phase PHASE2 Myasthenia Gravis RECRUITING NCT06193889
Standard lymphodepletion regimen Other Phase PHASE2 Myasthenia Gravis RECRUITING NCT06193889
Standard of Care Treatment Drug Phase PHASE2 Myasthenia Gravis RECRUITING NCT06193889
KYV-101 Other Phase PHASE2 Myasthenia Gravis RECRUITING NCT06193889
Standard lymphodepletion regimen Other Phase PHASE2 Myasthenia Gravis RECRUITING NCT06193889
Standard of Care Treatment Drug Phase PHASE2 Myasthenia Gravis RECRUITING NCT06193889
KYV-101 Other Phase PHASE2 Myasthenia Gravis RECRUITING NCT06193889
Standard lymphodepletion regimen Other Phase PHASE2 Myasthenia Gravis RECRUITING NCT06193889
Standard of Care Treatment Drug Phase PHASE2 Myasthenia Gravis RECRUITING NCT06193889
KYV-101 Other Phase PHASE2 Myasthenia Gravis RECRUITING NCT06193889
Standard lymphodepletion regimen Other Phase PHASE2 Myasthenia Gravis RECRUITING NCT06193889
Standard of Care Treatment Drug Phase PHASE2 Myasthenia Gravis RECRUITING NCT06193889
KYV-101 Other Phase PHASE2 Myasthenia Gravis RECRUITING NCT06193889
Standard lymphodepletion regimen Other Phase PHASE2 Myasthenia Gravis RECRUITING NCT06193889
Standard of Care Treatment Drug Phase PHASE2 Myasthenia Gravis RECRUITING NCT06193889
KYV-101 Other Phase PHASE2 Myasthenia Gravis RECRUITING NCT06193889
Standard lymphodepletion regimen Other Phase PHASE2 Myasthenia Gravis RECRUITING NCT06193889
Standard of Care Treatment Drug Phase PHASE2 Myasthenia Gravis RECRUITING NCT06193889
KYV-101 Other Phase PHASE2 Myasthenia Gravis RECRUITING NCT06193889
Standard lymphodepletion regimen Other Phase PHASE2 Myasthenia Gravis RECRUITING NCT06193889
Standard of Care Treatment Drug Phase PHASE2 Myasthenia Gravis RECRUITING NCT06193889
KYV-101 Other Phase PHASE2 Myasthenia Gravis RECRUITING NCT06193889
Standard lymphodepletion regimen Other Phase PHASE2 Myasthenia Gravis RECRUITING NCT06193889
Standard of Care Treatment Drug Phase PHASE2 Myasthenia Gravis RECRUITING NCT06193889
KYV-101 Other Phase PHASE2 Myasthenia Gravis RECRUITING NCT06193889
Standard lymphodepletion regimen Other Phase PHASE2 Myasthenia Gravis RECRUITING NCT06193889
Standard of Care Treatment Drug Phase PHASE2 Myasthenia Gravis RECRUITING NCT06193889
KYV-101 Other Phase PHASE2 Myasthenia Gravis RECRUITING NCT06193889
Standard lymphodepletion regimen Other Phase PHASE2 Myasthenia Gravis RECRUITING NCT06193889
Standard of Care Treatment Drug Phase PHASE2 Myasthenia Gravis RECRUITING NCT06193889
KYV-101 Other Phase PHASE2 Myasthenia Gravis RECRUITING NCT06193889
Standard lymphodepletion regimen Other Phase PHASE2 Myasthenia Gravis RECRUITING NCT06193889
Standard of Care Treatment Drug Phase PHASE2 Myasthenia Gravis RECRUITING NCT06193889
KYV-101 Other Phase PHASE2 Myasthenia Gravis RECRUITING NCT06193889
Standard lymphodepletion regimen Other Phase PHASE2 Myasthenia Gravis RECRUITING NCT06193889
Standard of Care Treatment Drug Phase PHASE2 Myasthenia Gravis RECRUITING NCT06193889
KYV-101 Other Phase PHASE2 Myasthenia Gravis RECRUITING NCT06193889
Standard lymphodepletion regimen Other Phase PHASE2 Myasthenia Gravis RECRUITING NCT06193889
Standard of Care Treatment Drug Phase PHASE2 Myasthenia Gravis RECRUITING NCT06193889
KYV-101 Other Phase PHASE2 Myasthenia Gravis RECRUITING NCT06193889
Standard lymphodepletion regimen Other Phase PHASE2 Myasthenia Gravis RECRUITING NCT06193889
Standard of Care Treatment Drug Phase PHASE2 Myasthenia Gravis RECRUITING NCT06193889
Anti-CD20 mAB Other Phase PHASE2 Multiple Sclerosis, Primary Progressive ACTIVE_NOT_RECRUITING NCT06384976
Standard lymphodepletion regimen Other Phase PHASE2 Multiple Sclerosis, Primary Progressive ACTIVE_NOT_RECRUITING NCT06384976
KYV-101 Other Phase PHASE2 Multiple Sclerosis, Primary Progressive ACTIVE_NOT_RECRUITING NCT06384976
Standard lymphodepletion regimen Other Phase PHASE2 Stiff-Person Syndrome ACTIVE_NOT_RECRUITING NCT06588491
KYV-101 Other Preclinical Refractory Lupus Nephritis RECRUITING NCT07403188
Standard lymphodepletion regimen Other Phase PHASE1 Systemic Sclerosis ACTIVE_NOT_RECRUITING NCT06400303
KYV-101 Other Phase PHASE1 Systemic Sclerosis ACTIVE_NOT_RECRUITING NCT06400303
Standard lymphodepletion regimen Other Phase PHASE1 Lupus Nephritis ACTIVE_NOT_RECRUITING NCT06342960
KYV-101 anti-CD19 CAR-T cell therapy Drug Phase PHASE1 Lupus Nephritis ACTIVE_NOT_RECRUITING NCT06342960
Standard lymphodepletion regimen Other Phase PHASE1 Lupus Nephritis ACTIVE_NOT_RECRUITING NCT05938725
KYV-101 anti-CD19 CAR-T cell therapy Drug Phase PHASE1 Lupus Nephritis ACTIVE_NOT_RECRUITING NCT05938725
Chemotherapy: fludarabine (FLU) Drug Phase PHASE1 Progressive Multiple Sclerosis ACTIVE_NOT_RECRUITING NCT06451159
Chemotherapy: cyclophosphamide (CYC) Drug Phase PHASE1 Progressive Multiple Sclerosis ACTIVE_NOT_RECRUITING NCT06451159
KYV-101 (Biological) - 1 ×10^8 cells Other Phase PHASE1 Progressive Multiple Sclerosis ACTIVE_NOT_RECRUITING NCT06451159
KYV-101 (Biological) - 0.33 ×10^8 cells Other Phase PHASE1 Progressive Multiple Sclerosis ACTIVE_NOT_RECRUITING NCT06451159
Standard lymphodepletion regimen Other Phase PHASE1 Multiple Sclerosis RECRUITING NCT06138132
KYV-101 anti-CD19 CAR-T cell therapy Drug Phase PHASE1 Multiple Sclerosis RECRUITING NCT06138132
Rituximab (active comparator) Other Phase PHASE1 Rheumatoid Arthritis ACTIVE_NOT_RECRUITING NCT06475495
KYV101 Other Phase PHASE1 Rheumatoid Arthritis ACTIVE_NOT_RECRUITING NCT06475495
KYV-101 Other Phase PHASE2 Myasthenia Gravis RECRUITING NCT06193889
Standard lymphodepletion regimen Other Phase PHASE2 Myasthenia Gravis RECRUITING NCT06193889
Standard of Care Treatment Drug Phase PHASE2 Myasthenia Gravis RECRUITING NCT06193889
Total products: 64