SymbolGNPX
NameGENPREX, INC.
SectorHEALTH CARE
RegionNorth America
IndustryBiotechnology: Pharmaceutical Preparations
Address3300 BEE CAVE ROAD,SUITE 650-227, AUSTIN, Texas, 78746, United States
Telephone+1 877 774-4679
Fax
Email
Websitehttps://www.genprex.com
IncorporationUNDEFINED
Incorporated On
Employees
Fiscal Year
Public Since
ExchangesNASDAQ
Auditor
Audit StatusNOT PROVIDED
Reporting Status
CIK0001595248
Description

Genprex, Inc. is a clinical-stage gene therapy company focused on developing life-changing therapies for patients with cancer and diabetes. Genprexs technologies are designed to administer disease-fighting genes to provide new therapies for large patient populations with cancer and diabetes who currently have limited treatment options. Genprex works with world-class institutions and collaborators to develop drug candidates to further its pipeline of gene therapies in order to provide novel treatment approaches. Genprexs oncology program utilizes its systemic, non-viral Oncoprex® Delivery System which encapsulates the gene-expressing plasmids using lipid-based nanoparticles in a lipoplex form. The resultant product is administered intravenously, where it is taken up by tumor cells that then express tumor suppressor proteins that were deficient in the tumor.

Additional info from NASDAQ:
Genprex, Inc. is a clinical-stage gene therapy company focused on developing life-changing therapies for patients with cancer and diabetes. Genprexs technologies are designed to administer disease-fighting genes to provide new therapies for large patient populations with cancer and diabetes who currently have limited treatment options. Genprex works with world-class institutions and collaborators to develop drug candidates to further its pipeline of gene therapies in order to provide novel treatment approaches. Genprexs oncology program utilizes its systemic, non-viral Oncoprex® Delivery System which encapsulates the gene-expressing plasmids using lipid-based nanoparticles in a lipoplex form. The resultant product is administered intravenously, where it is taken up by tumor cells that then express tumor suppressor proteins that were deficient in the tumor.

2026-05-11 18:53

New Form SCHEDULE 13G/A - Genprex, Inc. <b>Filed:</b> 2026-05-11 <b>AccNo:</b> 0001493152-26-022311 <b>Size:</b> 11 KB

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2026-04-30 12:09

Genprex Receives Patent Grant from The Israel Patent Office for the Combination of Reqorsa® Gene Therapy and PD-1 Antibodies to Treat Cancer

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2026-04-29 17:49

New Form ARS - Genprex, Inc. <b>Filed:</b> 2026-04-29 <b>AccNo:</b> 0001437749-26-013907 <b>Size:</b> 5 MB

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2026-04-28 11:07

(70% Positive) GENPREX, INC. (GNPX) Announces Clinical Development Update

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2026-04-28 11:03

Genprex Collaborators to Present Positive Preclinical Data on Diabetes Gene Therapy for Type 2 Diabetes at the 2026 American Society of Gene and Cell

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2026-04-22 12:06

Positive Clinical Data on Biomarkers in Patients Receiving Reqorsa® Gene Therapy To Be Released at the 2026 ASCO Annual Meeting

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2026-04-22 11:00

Positive Clinical Data on Biomarkers in Patients Receiving Reqorsa® Gene Therapy To Be Released at the 2026 ASCO Annual Meeting

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2026-04-21 12:46

Genprex Signs Sponsored Research Agreement to Study Biomarkers that May Predict Patient Response to Reqorsa® Gene Therapy

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2026-04-21 11:02

(99% Neutral) GENPREX, INC. (GNPX) Files Form 8-K

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2026-04-20 11:07

Genprex Collaborators Present Positive Preclinical Data on the Use of Reqorsa® Gene Therapy for the Treatment of Lung Cancer at the 2026 AACR Annual M

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Trial ID Title Phase Indication Status Start Date Completion Date Source
NCT05703971 Quaratusugene Ozeplasmid (Reqorsa) and Atezolizumab Maintenance Therapy in ES-S… Phase1 Small Cell Lung Cancer Extensive Stage Recruiting 2024-05-09 2027-08-01 ClinicalTrials.gov
NCT05062980 Quaratusugene Ozeplasmid (Reqorsa) in Combination With Pembrolizumab in Previou… Phase1 Non Small Cell Lung Cancer Terminated 2022-03-30 2025-02-03 ClinicalTrials.gov
NCT04486833 Quaratusugene Ozeplasmid (Reqorsa) and Osimertinib in Patients With Advanced Lu… Phase1 Carcinoma, Non-Small Cell Lung Recruiting 2021-09-03 2029-03-01 ClinicalTrials.gov
NCT01455389 TUSC2-nanoparticles and Erlotinib in Stage IV Lung Cancer Phase1 Lung Cancer Terminated 2014-02-01 2020-09-28 ClinicalTrials.gov
Total clinical trials: 4
Product Name Type Development Stage Therapeutic Area Study Status Trial ID
Diphenhydramine Other Phase PHASE1 Lung Cancer TERMINATED NCT01455389
Dexamethasone Other Phase PHASE1 Lung Cancer TERMINATED NCT01455389
Erlotinib Other Phase PHASE1 Lung Cancer TERMINATED NCT01455389
DOTAP:Chol-TUSC2 Other Phase PHASE1 Lung Cancer TERMINATED NCT01455389
Investigator's Treatment of Choice Drug Phase PHASE1 Non Small Cell Lung Cancer TERMINATED NCT05062980
ramucirumab Other Phase PHASE1 Non Small Cell Lung Cancer TERMINATED NCT05062980
docetaxel Other Phase PHASE1 Non Small Cell Lung Cancer TERMINATED NCT05062980
pembrolizumab Other Phase PHASE1 Non Small Cell Lung Cancer TERMINATED NCT05062980
quaratusugene ozeplasmid Other Phase PHASE1 Non Small Cell Lung Cancer TERMINATED NCT05062980
atezolizumab Other Phase PHASE1 Small Cell Lung Cancer Extensive Stage RECRUITING NCT05703971
quaratusugene ozeplasmid Other Phase PHASE1 Small Cell Lung Cancer Extensive Stage RECRUITING NCT05703971
Platinum-Based Chemotherapy Drug Phase PHASE1 Carcinoma, Non-Small Cell Lung RECRUITING NCT04486833
osimertinib Other Phase PHASE1 Carcinoma, Non-Small Cell Lung RECRUITING NCT04486833
quaratusugene ozeplasmid Other Phase PHASE1 Carcinoma, Non-Small Cell Lung RECRUITING NCT04486833
atezolizumab BIOLOGICAL Phase PHASE1 Small Cell Lung Cancer Extensive Stage RECRUITING NCT05703971
Investigator's Treatment of Choice DRUG Phase PHASE1 Non Small Cell Lung Cancer TERMINATED NCT05062980
ramucirumab DRUG Phase PHASE1 Non Small Cell Lung Cancer TERMINATED NCT05062980
docetaxel DRUG Phase PHASE1 Non Small Cell Lung Cancer TERMINATED NCT05062980
pembrolizumab DRUG Phase PHASE1 Non Small Cell Lung Cancer TERMINATED NCT05062980
Platinum-Based Chemotherapy DRUG Phase PHASE1 Carcinoma, Non-Small Cell Lung RECRUITING NCT04486833
osimertinib DRUG Phase PHASE1 Carcinoma, Non-Small Cell Lung RECRUITING NCT04486833
quaratusugene ozeplasmid BIOLOGICAL Phase PHASE1 Small Cell Lung Cancer Extensive Stage RECRUITING NCT05703971
Diphenhydramine DRUG Phase PHASE1 Lung Cancer TERMINATED NCT01455389
Dexamethasone DRUG Phase PHASE1 Lung Cancer TERMINATED NCT01455389
Erlotinib DRUG Phase PHASE1 Lung Cancer TERMINATED NCT01455389
DOTAP:Chol-TUSC2 DRUG Phase PHASE1 Lung Cancer TERMINATED NCT01455389
Total products: 26