SymbolENSC
NameENSYSCE BIOSCIENCES INC.
SectorHEALTH CARE
RegionNorth America
Industry-
Address92037 United States CA 7946 Ivanhoe Avenue Suite 201
Telephone(858)263-4196
Fax
Email
Websitehttps://ensysce.com/
IncorporationUS
Incorporated On
Employees
Fiscal Year12/31
Public Since
ExchangesOTC;NASDAQ
Auditor
Audit StatusAUDITED
Reporting StatusU.S. Reporting: SEC Reporting
CIK0001716947
Description

Ensysce Biosciences is a clinical-stage biotech company using its proprietary technology platforms to develop safer prescription drugs.

Additional info from NASDAQ:
Ensysce Biosciences Inc is a clinical-stage biotech company using its proprietary technology platforms to develop safer prescription drugs. The company is developing a new class of powerful, tamper-proof opioids that prevent both drug abuse and overdoses. Ensysces products are anticipated to provide safer options to treat severe pain and assist in preventing deaths caused by opioid abuse, reducing human and economic costs.

Additional info from OTC:
Ensysce Biosciences is a clinical-stage biotech company using its proprietary technology platforms to develop safer prescription drugs.

2026-05-08 12:00

Ensysce Biosciences CEO Presents at Inaugural Clinical Pain Symposium in Amsterdam

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2026-04-30 17:16

New Form S-8 - Ensysce Biosciences, Inc. <b>Filed:</b> 2026-04-30 <b>AccNo:</b> 0001493152-26-020504 <b>Size:</b> 295 KB

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2026-04-16 12:05

Ensysce Biosciences Secures IRB Approval of Final Phase of PF614-MPAR-102 Clinical Study

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2026-04-16 07:04

New Form EFFECT - Ensysce Biosciences, Inc. <b>Filed:</b> 2026-04-15 <b>AccNo:</b> 9999999995-26-001203 <b>Size:</b> 1 KB

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2026-04-07 12:05

Ensysce Biosciences Secures Second Financing From 2025 Agreement to Advance Breakthrough Pain Programs

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2026-04-03 20:14

(99% Neutral) ENSYSCE BIOSCIENCES INC. (ENSC) Announces Executive Departure

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2026-03-30 21:37

(10% Negative) ENSYSCE BIOSCIENCES INC. (ENSC) Reports Q1 2026 Financial Results

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2026-03-30 20:50

Ensysce Biosciences Reports Fourth Quarter and Full Year 2025 Financial Results

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2026-03-23 12:00

(99% Neutral) ENSYSCE BIOSCIENCES INC. (ENSC) Announces Executive Changes

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2026-03-05 02:59

NASDAQ symbol attribute type Financial_Status was changed. Previous value: Normal. New value: Deficient.

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Trial ID Title Phase Indication Status Start Date Completion Date Source
NCT06602271 PF614 Analgesic Activity in Acute Postoperative Pain (PF614-301) Phase3 Postoperative Pain, Acute Recruiting 2025-12-09 2026-11-01 ClinicalTrials.gov
NCT06500793 Single Dose Study, Pharmacokinetics of Oxycodone and PF614 Co-Administered With… Phase1 Pharmacokinetics Recruiting 2024-11-24 2026-12-31 ClinicalTrials.gov
NCT06629402 Assessment of PF614 Effects on Experimental Pain in the Cold Pressure Test (PF6… Phase2 Acute Pain Completed 2023-10-05 2023-11-15 ClinicalTrials.gov
NCT05571345 A Study to Evaluate the Oral Abuse Potential of PF614 in Non-Dependent Recreati… Phase1 Recreational Drug Use Completed 2022-10-05 2022-12-28 ClinicalTrials.gov
NCT05567354 A Study to Evaluate the Intranasal Abuse Potential of PF614 in Non-Dependent Re… Phase1 Recreational Drug Use Completed 2022-06-10 2022-08-31 ClinicalTrials.gov
NCT05090280 Pharmacokinetics of Oxycodone and PF614 Co-Administered with Nafamostat (PF614-… Phase1 Pharmacokinetics Completed 2021-12-01 2023-04-26 ClinicalTrials.gov
NCT05043766 Evaluation of Oral PF614 Relative to OxyContin (PF614-102) Phase1 Healthy Volunteers Completed 2021-09-08 2022-03-21 ClinicalTrials.gov
NCT04406415 Oral Nafamostat in Healthy Volunteers (NAF-101) Phase1 Pharmacokinetics Completed 2020-09-21 2021-05-14 ClinicalTrials.gov
NCT02454712 Study of PF614 Compared to OxyContin® in Healthy Volunteers (PF614-101) Phase1 Healthy Completed 2016-11-16 2018-01-18 ClinicalTrials.gov
Total clinical trials: 9
Product Name Type Development Stage Therapeutic Area Study Status Trial ID
Placebo Other Phase PHASE1 Recreational Drug Use COMPLETED NCT05571345
Oxycodone Hydrochloride 40 mg Other Phase PHASE1 Recreational Drug Use COMPLETED NCT05571345
PF614 Other Phase PHASE1 Recreational Drug Use COMPLETED NCT05571345
Placebo Other Phase PHASE1 Recreational Drug Use COMPLETED NCT05567354
Oxycodone Other Phase PHASE1 Recreational Drug Use COMPLETED NCT05567354
PF614 Other Phase PHASE1 Recreational Drug Use COMPLETED NCT05567354
Nafamostat Mesylate Other Phase PHASE1 Pharmacokinetics COMPLETED NCT05090280
Naltrexone Hydrochloride Other Phase PHASE1 Pharmacokinetics COMPLETED NCT05090280
PF614 solution Other Phase PHASE1 Pharmacokinetics COMPLETED NCT05090280
OxyContin Other Phase PHASE1 Healthy Volunteers COMPLETED NCT05043766
Naltrexone Hydrochloride Other Phase PHASE1 Healthy Volunteers COMPLETED NCT05043766
PF614 Other Phase PHASE1 Healthy Volunteers COMPLETED NCT05043766
Placebo Other Phase PHASE1 Pharmacokinetics COMPLETED NCT04406415
Nafamostat Mesilate Other Phase PHASE1 Pharmacokinetics COMPLETED NCT04406415
Naltrexone Hydrochloride Other Phase PHASE1 Healthy COMPLETED NCT02454712
Oxycodone extended-release Other Phase PHASE1 Healthy COMPLETED NCT02454712
PF614 Other Phase PHASE1 Healthy COMPLETED NCT02454712
Placebo Other Phase PHASE2 Acute Pain COMPLETED NCT06629402
PF614 Other Phase PHASE2 Acute Pain COMPLETED NCT06629402
Placebo Other Phase PHASE3 Postoperative Pain, Acute RECRUITING NCT06602271
PF614 capsule Other Phase PHASE3 Postoperative Pain, Acute RECRUITING NCT06602271
Nafamostat Mesylate Other Phase PHASE1 Pharmacokinetics RECRUITING NCT06500793
PF614 capsule Other Phase PHASE1 Pharmacokinetics RECRUITING NCT06500793
Total products: 23