SymbolCRSP
NameCRISPR THERAPEUTICS AG
SectorHEALTH CARE
RegionEurope
IndustryBiotechnology: Biological Products (No Diagnostic Substances)
AddressBAARERSTRASSE 14, ZUG, 6300, Switzerland
Telephone+41 41 - 561 32 77
Fax
Email
Websitehttps://www.crisprtx.com
IncorporationUNDEFINED
Incorporated On
Employees
Fiscal Year
Public Since
ExchangesNASDAQ
Auditor
Audit StatusNOT PROVIDED
Reporting Status
CIK0001674416
Description

CRISPR Therapeutics is a gene editing company focused on the development of CRISPR/Cas9-based therapeutics. CRISPR/Cas9 stands for Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)/CRISPR-associated protein 9 (Cas9), which is a revolutionary technology for precisely altering specific sequences of genomic DNA. The company is focused on using this technology to treat genetically defined diseases. CRISPRs most advanced pipeline candidate, CTX001, is in collaboration with Vertex Pharmaceuticals and targets sickle cell disease and transfusion-dependent beta-thalassemia, which have high unmet medical needs. The company is progressing additional gene editing programs for immuno-oncology, as well as a stem cell-derived therapy for the treatment of Type 1 diabetes.

Additional info from NASDAQ:
CRISPR Therapeutics is a gene editing company focused on the development of CRISPR/Cas9-based therapeutics. CRISPR/Cas9 stands for Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)/CRISPR-associated protein 9 (Cas9), which is a revolutionary technology for precisely altering specific sequences of genomic DNA. The company is focused on using this technology to treat genetically defined diseases. CRISPRs most advanced pipeline candidate, CTX001, is in collaboration with Vertex Pharmaceuticals and targets sickle cell disease and transfusion-dependent beta-thalassemia, which have high unmet medical needs. The company is progressing additional gene editing programs for immuno-oncology, as well as a stem cell-derived therapy for the treatment of Type 1 diabetes.

2026-05-06 12:30

CRISPR Therapeutics to Present at the Bank of America Securities 2026 Global Healthcare Conference

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2026-05-04 20:41

(30% Negative) CRISPR THERAPEUTICS AG (CRSP) Reports Q2 2026 Financial Results

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2026-05-04 20:30

CRISPR Therapeutics Provides Business Update and Reports First Quarter 2026 Financial Results

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2026-04-30 13:41

New Form SCHEDULE 13G/A - CRISPR Therapeutics AG <b>Filed:</b> 2026-04-30 <b>AccNo:</b> 0001104659-26-052492 <b>Size:</b> 13 KB

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2026-04-21 09:19

New Form ARS - CRISPR Therapeutics AG <b>Filed:</b> 2026-04-21 <b>AccNo:</b> 0001193125-26-165183 <b>Size:</b> 3 MB

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2026-04-21 09:12

New Form DEFA14A - CRISPR Therapeutics AG <b>Filed:</b> 2026-04-21 <b>AccNo:</b> 0001193125-26-165164 <b>Size:</b> 13 MB

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2026-04-21 09:06

New Form DEF 14A - CRISPR Therapeutics AG <b>Filed:</b> 2026-04-21 <b>AccNo:</b> 0001193125-26-165158 <b>Size:</b> 15 MB

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2026-04-02 17:24

New Form PRE 14A - CRISPR Therapeutics AG <b>Filed:</b> 2026-04-02 <b>AccNo:</b> 0001193125-26-140224 <b>Size:</b> 13 MB

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2026-03-24 21:38

KASINGER JAMES R. 🟡 adjusted position in 60.3K shares (3 derivative) of CRISPR Therapeutics AG (CRSP) at $46.78 ($1.9M) Transaction Date: Mar 20, 2026 | Filing ID: 122274

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2026-03-24 21:37

Prasad Raju 🟡 adjusted position in 62.3K shares (3 derivative) of CRISPR Therapeutics AG (CRSP) at $46.78 ($2.0M) Transaction Date: Mar 20, 2026 | Filing ID: 122268

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Trial ID Title Phase Indication Status Start Date Completion Date Source
NCT07549698 Safety and Preliminary Efficacy of CTX112 in Adult Participants With Relapsed/R… Phase1 Warm Autoimmune Hemolytic Anemia (WAIHA) Not_Yet_Recruiting 2026-04-01 2033-12-01 ClinicalTrials.gov
NCT07549698 Safety and Preliminary Efficacy of CTX112 in Adult Participants With Relapsed/R… Phase1 Warm Autoimmune Hemolytic Anemia (WAIHA) Not_Yet_Recruiting 2026-04-01 2033-12-01 ClinicalTrials.gov
NCT06907875 A First-in-human Study of EPI-321 in Facioscapulohumeral Muscular Dystrophy Phase1 Facioscapulohumeral Muscular Dystrophy Recruiting 2025-05-08 2032-04-30 ClinicalTrials.gov
NCT06907875 A First-in-human Study of EPI-321 in Facioscapulohumeral Muscular Dystrophy Phase1 Facioscapulohumeral Muscular Dystrophy Recruiting 2025-05-08 2032-04-30 ClinicalTrials.gov
NCT06925542 A Safety and Efficacy Study Evaluating CTX112 in Adult Subjects With Refractory… Phase1 SLE (Systemic Lupus) Recruiting 2025-03-10 2031-12-31 ClinicalTrials.gov
NCT06925542 A Safety and Efficacy Study Evaluating CTX112 in Adult Subjects With Refractory… Phase1 SLE (Systemic Lupus) Recruiting 2025-03-10 2031-12-31 ClinicalTrials.gov
NCT06492304 A Safety and Efficacy Study Evaluating CTX131 in Adult Subjects With Relapsed/R… Phase1 T Cell Lymphoma Completed 2024-08-13 2026-03-11 ClinicalTrials.gov
NCT06492304 A Safety and Efficacy Study Evaluating CTX131 in Adult Subjects With Relapsed/R… Phase1 T Cell Lymphoma Completed 2024-08-13 2026-03-11 ClinicalTrials.gov
NCT07491172 A Safety and Tolerability Trial Evaluating CTX310 in Participants With Refracto… Phase1 Cardiovascular Recruiting 2024-06-21 2028-06-01 ClinicalTrials.gov
NCT07491172 A Safety and Tolerability Trial Evaluating CTX310 in Participants With Refracto… Phase1 Cardiovascular Recruiting 2024-06-21 2028-06-01 ClinicalTrials.gov
NCT06208878 A Long-term Follow-up Study of Subjects Who Received CRISPR CAR T Cellular Ther… Hematologic Malignancy Enrolling_By_Invitation 2023-11-22 2038-08-01 ClinicalTrials.gov
NCT06208878 A Long-term Follow-up Study of Subjects Who Received CRISPR CAR T Cellular Ther… Hematologic Malignancy Enrolling_By_Invitation 2023-11-22 2038-08-01 ClinicalTrials.gov
NCT05795595 A Safety and Efficacy Study Evaluating CTX131 in Adult Subjects With Relapsed o… Phase1 Clear Cell Renal Cell Carcinoma Completed 2023-03-13 2025-09-18 ClinicalTrials.gov
NCT05795595 A Safety and Efficacy Study Evaluating CTX131 in Adult Subjects With Relapsed o… Phase1 Clear Cell Renal Cell Carcinoma Completed 2023-03-13 2025-09-18 ClinicalTrials.gov
NCT05643742 A Safety and Efficacy Study Evaluating CTX112 in Subjects With Relapsed or Refr… Phase1 B-cell Lymphoma Recruiting 2023-03-10 2030-02-01 ClinicalTrials.gov
NCT05643742 A Safety and Efficacy Study Evaluating CTX112 in Subjects With Relapsed or Refr… Phase1 B-cell Lymphoma Recruiting 2023-03-10 2030-02-01 ClinicalTrials.gov
NCT05565248 An Open-Label, FIH Study Evaluating the Safety, Tolerability, and Efficacy of V… Phase1 Diabetes Mellitus Recruiting 2023-01-20 2025-08-01 ClinicalTrials.gov
NCT05565248 An Open-Label, FIH Study Evaluating the Safety, Tolerability, and Efficacy of V… Phase1 Diabetes Mellitus Recruiting 2023-01-20 2025-08-01 ClinicalTrials.gov
NCT05210530 An Open-Label, FIH Study Evaluating the Safety and Tolerability of VCTX210A Com… Phase1 Diabetes Mellitus Completed 2022-01-24 2023-01-19 ClinicalTrials.gov
NCT05210530 An Open-Label, FIH Study Evaluating the Safety and Tolerability of VCTX210A Com… Phase1 Diabetes Mellitus Completed 2022-01-24 2023-01-19 ClinicalTrials.gov
NCT04502446 A Safety and Efficacy Study Evaluating CTX130 in Subjects With Relapsed or Refr… Phase1 T Cell Lymphoma Terminated 2020-07-31 2024-08-30 ClinicalTrials.gov
NCT04502446 A Safety and Efficacy Study Evaluating CTX130 in Subjects With Relapsed or Refr… Phase1 T Cell Lymphoma Terminated 2020-07-31 2024-08-30 ClinicalTrials.gov
NCT04438083 A Safety and Efficacy Study Evaluating CTX130 in Subjects With Relapsed or Refr… Phase1 Renal Cell Carcinoma Terminated 2020-06-16 2024-10-08 ClinicalTrials.gov
NCT04438083 A Safety and Efficacy Study Evaluating CTX130 in Subjects With Relapsed or Refr… Phase1 Renal Cell Carcinoma Terminated 2020-06-16 2024-10-08 ClinicalTrials.gov
NCT04244656 A Safety and Efficacy Study Evaluating CTX120 in Subjects With Relapsed or Refr… Phase1 Multiple Myeloma Terminated 2020-01-22 2024-01-04 ClinicalTrials.gov
NCT04244656 A Safety and Efficacy Study Evaluating CTX120 in Subjects With Relapsed or Refr… Phase1 Multiple Myeloma Terminated 2020-01-22 2024-01-04 ClinicalTrials.gov
NCT04035434 A Safety and Efficacy Study Evaluating CTX110 in Subjects With Relapsed or Refr… Phase1 B-cell Malignancy Terminated 2019-07-22 2024-10-04 ClinicalTrials.gov
NCT04035434 A Safety and Efficacy Study Evaluating CTX110 in Subjects With Relapsed or Refr… Phase1 B-cell Malignancy Terminated 2019-07-22 2024-10-04 ClinicalTrials.gov
Total clinical trials: 28
Product Name Type Development Stage Therapeutic Area Study Status Trial ID
VCTX210A unit Other Phase PHASE1 Diabetes Mellitus COMPLETED NCT05210530
VCTX211 Other Phase PHASE1 Diabetes Mellitus RECRUITING NCT05565248
CTX130 Other Phase PHASE1 T Cell Lymphoma TERMINATED NCT04502446
CTX130 Other Phase PHASE1 Renal Cell Carcinoma TERMINATED NCT04438083
CTX120 Other Phase PHASE1 Multiple Myeloma TERMINATED NCT04244656
Non Interventional Other Preclinical Hematologic Malignancy ENROLLING_BY_INVITATION NCT06208878
CTX110 Other Phase PHASE1 B-cell Malignancy TERMINATED NCT04035434
CTX112 Other Phase PHASE1 B-cell Lymphoma RECRUITING NCT05643742
CTX131 Other Phase PHASE1 Clear Cell Renal Cell Carcinoma COMPLETED NCT05795595
CTX112 Other Phase PHASE1 SLE (Systemic Lupus) RECRUITING NCT06925542
CTX310 Other Phase PHASE1 Cardiovascular RECRUITING NCT07491172
CTX131 Other Phase PHASE1 T Cell Lymphoma COMPLETED NCT06492304
EPI-321 Other Phase PHASE1 Facioscapulohumeral Muscular Dystrophy RECRUITING NCT06907875
CTX112 Other Phase PHASE1 Warm Autoimmune Hemolytic Anemia (WAIHA) NOT_YET_RECRUITING NCT07549698
CTX112 Other Phase PHASE1 Warm Autoimmune Hemolytic Anemia (WAIHA) NOT_YET_RECRUITING NCT07549698
CTX112 Other Phase PHASE1 Warm Autoimmune Hemolytic Anemia (WAIHA) NOT_YET_RECRUITING NCT07549698
CTX112 Other Phase PHASE1 Warm Autoimmune Hemolytic Anemia (WAIHA) NOT_YET_RECRUITING NCT07549698
CTX112 Other Phase PHASE1 Warm Autoimmune Hemolytic Anemia (WAIHA) NOT_YET_RECRUITING NCT07549698
CTX112 Other Phase PHASE1 Warm Autoimmune Hemolytic Anemia (WAIHA) NOT_YET_RECRUITING NCT07549698
CTX112 Other Phase PHASE1 Warm Autoimmune Hemolytic Anemia (WAIHA) NOT_YET_RECRUITING NCT07549698
CTX112 Other Phase PHASE1 Warm Autoimmune Hemolytic Anemia (WAIHA) NOT_YET_RECRUITING NCT07549698
CTX112 Other Phase PHASE1 Warm Autoimmune Hemolytic Anemia (WAIHA) NOT_YET_RECRUITING NCT07549698
CTX112 Other Phase PHASE1 Warm Autoimmune Hemolytic Anemia (WAIHA) NOT_YET_RECRUITING NCT07549698
CTX112 Other Phase PHASE1 Warm Autoimmune Hemolytic Anemia (WAIHA) NOT_YET_RECRUITING NCT07549698
CTX112 Other Phase PHASE1 Warm Autoimmune Hemolytic Anemia (WAIHA) NOT_YET_RECRUITING NCT07549698
CTX112 Other Phase PHASE1 Warm Autoimmune Hemolytic Anemia (WAIHA) NOT_YET_RECRUITING NCT07549698
EPI-321 Other Phase PHASE1 Facioscapulohumeral Muscular Dystrophy RECRUITING NCT06907875
EPI-321 Other Phase PHASE1 Facioscapulohumeral Muscular Dystrophy RECRUITING NCT06907875
EPI-321 Other Phase PHASE1 Facioscapulohumeral Muscular Dystrophy RECRUITING NCT06907875
EPI-321 Other Phase PHASE1 Facioscapulohumeral Muscular Dystrophy RECRUITING NCT06907875
EPI-321 Other Phase PHASE1 Facioscapulohumeral Muscular Dystrophy RECRUITING NCT06907875
EPI-321 Other Phase PHASE1 Facioscapulohumeral Muscular Dystrophy RECRUITING NCT06907875
EPI-321 Other Phase PHASE1 Facioscapulohumeral Muscular Dystrophy RECRUITING NCT06907875
EPI-321 BIOLOGICAL Phase PHASE1 Facioscapulohumeral Muscular Dystrophy RECRUITING NCT06907875
CTX310 DRUG Phase PHASE1 Cardiovascular RECRUITING NCT07491172
Non Interventional OTHER Preclinical Hematologic Malignancy ENROLLING_BY_INVITATION NCT06208878
CTX131 BIOLOGICAL Phase PHASE1 Clear Cell Renal Cell Carcinoma COMPLETED NCT05795595
CTX112 BIOLOGICAL Phase PHASE1 B-cell Lymphoma RECRUITING NCT05643742
CTX130 BIOLOGICAL Phase PHASE1 T Cell Lymphoma TERMINATED NCT04502446
CTX120 BIOLOGICAL Phase PHASE1 Multiple Myeloma TERMINATED NCT04244656
CTX110 BIOLOGICAL Phase PHASE1 B-cell Malignancy TERMINATED NCT04035434
Total products: 41