SymbolBCYC
NameBICYCLE THERAPEUTICS PLC
SectorHEALTH CARE
RegionEurope
IndustryBiotechnology: Pharmaceutical Preparations
AddressB900, BABRAHAM RESEARCH CAMPUS, CAMBRIDGE, CB22 3AT, United Kingdom
Telephone+44 1223261503
Fax
Email
Websitehttps://www.bicycletherapeutics.com
IncorporationUNDEFINED
Incorporated On
Employees
Fiscal Year
Public Since
ExchangesNASDAQ
Auditor
Audit StatusNOT PROVIDED
Reporting Status
CIK
Description

Bicycle Therapeutics PLC is a clinical-stage biopharmaceutical company developing a novel class of medicines which are referred to as Bicycles. The Bicycles are synthetic short peptides constrained to form two loops which stabilize their structural geometry. Its initial internal programs are focused on oncology indications with high unmet medical need.

Additional info from NASDAQ:
Bicycle Therapeutics PLC is a clinical-stage biopharmaceutical company developing a novel class of medicines which are referred to as Bicycles. The Bicycles are synthetic short peptides constrained to form two loops which stabilize their structural geometry. Its initial internal programs are focused on oncology indications with high unmet medical need.

2026-04-22 17:06

New Form DEF 14A - BICYCLE THERAPEUTICS PLC <b>Filed:</b> 2026-04-22 <b>AccNo:</b> 0001104659-26-046806 <b>Size:</b> 4 MB

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2026-04-20 11:06

(90% Positive) BICYCLE THERAPEUTICS PLC (BCYC) Provides Update on molecules for radiopharmaceutical use CAMBRIDGE

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2026-04-20 11:00

Bicycle Therapeutics Provides Update on Nuzefatide Pevedotin and EphA2 Pipeline at the AACR Annual Meeting 2026

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2026-04-06 22:30

Hannay Michael Charles Ferguson 🔴 sold 1.8K shares of BICYCLE THERAPEUTICS PLC (BCYC) at $5.05 Transaction Date: Apr 02, 2026 | Filing ID: 000004

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2026-04-06 22:30

Thompson Travis Alvin 🔴 sold 901 shares of BICYCLE THERAPEUTICS PLC (BCYC) at $5.05 Transaction Date: Apr 02, 2026 | Filing ID: 000006

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2026-04-06 22:30

Perry Jennifer Scott 🔴 sold 1.4K shares of BICYCLE THERAPEUTICS PLC (BCYC) at $5.05 Transaction Date: Apr 02, 2026 | Filing ID: 000005

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2026-04-06 22:30

Lee Kevin 🔴 sold 7.7K shares of BICYCLE THERAPEUTICS PLC (BCYC) at $5.05 Transaction Date: Apr 02, 2026 | Filing ID: 000004

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2026-04-06 22:30

Skynner Michael 🔴 sold 2.4K shares of BICYCLE THERAPEUTICS PLC (BCYC) at $5.05 Transaction Date: Apr 02, 2026 | Filing ID: 000004

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2026-04-02 21:39

📋 Young Alethia (Officer) plans to sell 2K shares of BICYCLE THERAPEUTICS PLC (at $4.91 each, total $10K) Filed: Apr 02, 2026 | ID: 000134

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2026-04-02 21:27

📋 Perry Jennifer Scott (Officer) plans to sell 2K shares of BICYCLE THERAPEUTICS PLC (at $4.91 each, total $7K) Filed: Apr 02, 2026 | ID: 000133

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Trial ID Title Phase Indication Status Start Date Completion Date Source
NCT03486730 BT1718 in Patients with Advanced Solid Tumours. Phase1 Advanced Solid Tumours Completed 2018-01-24 2023-11-20 ClinicalTrials.gov
Total clinical trials: 1
Product Name Type Development Stage Therapeutic Area Study Status Trial ID
Avelumab Other Phase PHASE2 Metastatic Urothelial Cancer ACTIVE_NOT_RECRUITING NCT06225596
Gemcitabine + cisplatin Or carboplatin Other Phase PHASE2 Metastatic Urothelial Cancer ACTIVE_NOT_RECRUITING NCT06225596
Pembrolizumab Other Phase PHASE2 Metastatic Urothelial Cancer ACTIVE_NOT_RECRUITING NCT06225596
BT8009 Other Phase PHASE2 Metastatic Urothelial Cancer ACTIVE_NOT_RECRUITING NCT06225596
nuzefatide pevedotin (BT5528) Other Phase PHASE2 Pancreatic Ductal Adenocarcinoma (PDAC) RECRUITING NCT07450859
nuzefatide pevedotin (BT5528) Other Phase PHASE2 Pancreatic Ductal Adenocarcinoma (PDAC) RECRUITING NCT07450859
Avelumab Other Phase PHASE2 Metastatic Urothelial Cancer ACTIVE_NOT_RECRUITING NCT06225596
Gemcitabine + cisplatin Or carboplatin Other Phase PHASE2 Metastatic Urothelial Cancer ACTIVE_NOT_RECRUITING NCT06225596
Pembrolizumab Other Phase PHASE2 Metastatic Urothelial Cancer ACTIVE_NOT_RECRUITING NCT06225596
BT8009 Other Phase PHASE2 Metastatic Urothelial Cancer ACTIVE_NOT_RECRUITING NCT06225596
nuzefatide pevedotin (BT5528) Other Phase PHASE2 Pancreatic Ductal Adenocarcinoma (PDAC) RECRUITING NCT07450859
Avelumab Other Phase PHASE2 Metastatic Urothelial Cancer ACTIVE_NOT_RECRUITING NCT06225596
Gemcitabine + cisplatin Or carboplatin Other Phase PHASE2 Metastatic Urothelial Cancer ACTIVE_NOT_RECRUITING NCT06225596
Pembrolizumab Other Phase PHASE2 Metastatic Urothelial Cancer ACTIVE_NOT_RECRUITING NCT06225596
BT8009 Other Phase PHASE2 Metastatic Urothelial Cancer ACTIVE_NOT_RECRUITING NCT06225596
nuzefatide pevedotin (BT5528) Other Phase PHASE2 Pancreatic Ductal Adenocarcinoma (PDAC) RECRUITING NCT07450859
Avelumab Other Phase PHASE2 Metastatic Urothelial Cancer ACTIVE_NOT_RECRUITING NCT06225596
Gemcitabine + cisplatin Or carboplatin Other Phase PHASE2 Metastatic Urothelial Cancer ACTIVE_NOT_RECRUITING NCT06225596
Pembrolizumab Other Phase PHASE2 Metastatic Urothelial Cancer ACTIVE_NOT_RECRUITING NCT06225596
BT8009 Other Phase PHASE2 Metastatic Urothelial Cancer ACTIVE_NOT_RECRUITING NCT06225596
nuzefatide pevedotin (BT5528) Other Phase PHASE2 Pancreatic Ductal Adenocarcinoma (PDAC) RECRUITING NCT07450859
Avelumab Other Phase PHASE2 Metastatic Urothelial Cancer ACTIVE_NOT_RECRUITING NCT06225596
Gemcitabine + cisplatin Or carboplatin Other Phase PHASE2 Metastatic Urothelial Cancer ACTIVE_NOT_RECRUITING NCT06225596
Pembrolizumab Other Phase PHASE2 Metastatic Urothelial Cancer ACTIVE_NOT_RECRUITING NCT06225596
BT8009 Other Phase PHASE2 Metastatic Urothelial Cancer ACTIVE_NOT_RECRUITING NCT06225596
nuzefatide pevedotin (BT5528) Other Phase PHASE2 Pancreatic Ductal Adenocarcinoma (PDAC) RECRUITING NCT07450859
Avelumab Other Phase PHASE2 Metastatic Urothelial Cancer ACTIVE_NOT_RECRUITING NCT06225596
Gemcitabine + cisplatin Or carboplatin Other Phase PHASE2 Metastatic Urothelial Cancer ACTIVE_NOT_RECRUITING NCT06225596
Pembrolizumab Other Phase PHASE2 Metastatic Urothelial Cancer ACTIVE_NOT_RECRUITING NCT06225596
BT8009 Other Phase PHASE2 Metastatic Urothelial Cancer ACTIVE_NOT_RECRUITING NCT06225596
nuzefatide pevedotin (BT5528) Other Phase PHASE2 Pancreatic Ductal Adenocarcinoma (PDAC) RECRUITING NCT07450859
Avelumab Other Phase PHASE2 Metastatic Urothelial Cancer ACTIVE_NOT_RECRUITING NCT06225596
Gemcitabine + cisplatin Or carboplatin Other Phase PHASE2 Metastatic Urothelial Cancer ACTIVE_NOT_RECRUITING NCT06225596
Pembrolizumab Other Phase PHASE2 Metastatic Urothelial Cancer ACTIVE_NOT_RECRUITING NCT06225596
BT8009 Other Phase PHASE2 Metastatic Urothelial Cancer ACTIVE_NOT_RECRUITING NCT06225596
nuzefatide pevedotin (BT5528) Other Phase PHASE2 Pancreatic Ductal Adenocarcinoma (PDAC) RECRUITING NCT07450859
Total products: 36