SymbolAVIR
NameATEA PHARMACEUTICALS, INC.
SectorHEALTH CARE
RegionNorth America
IndustryBiotechnology: Pharmaceutical Preparations
Address125 SUMMER STREET, BOSTON, Massachusetts, 02110, United States
Telephone+1 857 284-8891
Fax
Email
Websitehttps://www.ateapharma.com
IncorporationUNDEFINED
Incorporated On
Employees
Fiscal Year
Public Since
ExchangesNASDAQ
Auditor
Audit StatusNOT PROVIDED
Reporting Status
CIK0001593899
Description

Atea Pharmaceuticals Inc is a clinical-stage biopharmaceutical company engaged in discovering and developing therapies to address the unmet medical needs of patients with severe viral diseases. Its programs are focused on the development of orally- administered direct acting antivirals for the treatment of patients with COVID-19 in the hospital and community settings, the treatment of patients with chronic hepatitis C infection, the treatment of patients with dengue, and the treatment of high-risk patients with severe respiratory syncytial virus infection. The companys medicinal chemistry, virology, and pharmacology expertise, bolstered by its collective experience in drug development, enables it to pioneer new advancements in antiviral science.

Additional info from NASDAQ:
Atea Pharmaceuticals Inc is a clinical-stage biopharmaceutical company engaged in discovering and developing therapies to address the unmet medical needs of patients with severe viral diseases. Its programs are focused on the development of orally- administered direct acting antivirals for the treatment of patients with COVID-19 in the hospital and community settings, the treatment of patients with chronic hepatitis C infection, the treatment of patients with dengue, and the treatment of high-risk patients with severe respiratory syncytial virus infection. The companys medicinal chemistry, virology, and pharmacology expertise, bolstered by its collective experience in drug development, enables it to pioneer new advancements in antiviral science.

2026-06-25 11:00

Atea Pharmaceuticals Completes Patient Enrollment in Phase 3 C-FORWARD Trial Evaluating Bemnifosbuvir and Ruzasvir for Treatment of Hepatitis C Virus

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2026-06-23 21:00

Lucidi Bruno 🟡 adjusted position in 64.4K shares (3 derivative) of Atea Pharmaceuticals, Inc. (AVIR) at $4.36 Transaction Date: Jun 18, 2026 | Filing ID: 279728

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2026-06-23 21:00

BERGER FRANKLIN M 🟡 adjusted position in 64.4K shares (3 derivative) of Atea Pharmaceuticals, Inc. (AVIR) at $4.36 Transaction Date: Jun 18, 2026 | Filing ID: 279726

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2026-06-23 21:00

Berman Howard 🟢 acquired 64.4K shares (2 derivative) of Atea Pharmaceuticals, Inc. (AVIR) at $4.36 Transaction Date: Jun 18, 2026 | Filing ID: 279723

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2026-06-23 21:00

DUNCAN BARBARA GAYLE 🟡 adjusted position in 64.4K shares (3 derivative) of Atea Pharmaceuticals, Inc. (AVIR) at $4.36 Transaction Date: Jun 18, 2026 | Filing ID: 279721

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2026-06-23 21:00

Polsky Bruce 🟡 adjusted position in 64.4K shares (3 derivative) of Atea Pharmaceuticals, Inc. (AVIR) at $4.36 Transaction Date: Jun 18, 2026 | Filing ID: 279719

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2026-06-23 21:00

Murphy Polly A. 🟡 adjusted position in 64.4K shares (3 derivative) of Atea Pharmaceuticals, Inc. (AVIR) at $4.36 Transaction Date: Jun 18, 2026 | Filing ID: 279718

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2026-06-23 21:00

Adams Jerome M. 🟡 adjusted position in 64.4K shares (3 derivative) of Atea Pharmaceuticals, Inc. (AVIR) at $4.36 Transaction Date: Jun 18, 2026 | Filing ID: 279720

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2026-06-23 21:00

KIRSCH ARTHUR S 🟢 acquired 64.4K shares (2 derivative) of Atea Pharmaceuticals, Inc. (AVIR) at $4.36 Transaction Date: Jun 18, 2026 | Filing ID: 279717

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2026-06-22 20:53

(99% Neutral) ATEA PHARMACEUTICALS, INC. (AVIR) Announces Regulatory Update

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Trial ID Title Phase Indication Status Start Date Completion Date Source
NCT07272889 Drug-drug Interaction Study of Bemnifosbuvir/Ruzasvir (BEM/RZR) and Ethinyl Est… Phase1 Healthy Volunteer Study Completed 2025-12-04 2026-02-17 ClinicalTrials.gov
NCT07037277 C-Forward: Efficacy and Safety of BEM/RZR vs SOF/VEL in Subjects With Chronic H… Phase3 HEPATITIS C VIRUS CHRONIC INFECTION Active_Not_Recruiting 2025-06-02 2027-03-01 ClinicalTrials.gov
NCT07007806 Drug-drug Interaction Study of Omeprazole and Bemnifosbuvir/Ruzasvir Phase1 Healthy Volunteer Study Completed 2025-05-09 2025-06-28 ClinicalTrials.gov
NCT06911320 Study of Bemnifosbuvir/Ruzasvir as a Fixed-dose Combination in Subjects With No… Phase1 Healthy Volunteer Study Recruiting 2025-04-09 2026-05-01 ClinicalTrials.gov
NCT06921941 Drug-drug Interaction Study of Bemnifosbuvir/Ruzasvir (BEM/RZR) and Digoxin and… Phase1 Healthy Volunteer Study Completed 2025-04-08 2025-07-02 ClinicalTrials.gov
NCT06868264 C-BEYOND: Efficacy and Safety of BEM/RZR vs. SOF/VEL in Subjects With Chronic H… Phase3 HEPATITIS C VIRUS CHRONIC INFECTION Active_Not_Recruiting 2025-04-07 2026-12-01 ClinicalTrials.gov
NCT07314346 Drug-drug Interaction Study of Bemnifosbuvir/Ruzasvir (BEM/RZR) and Buprenorphi… Phase1 Healthy Volunteer Study Recruiting 2025-01-07 2026-08-01 ClinicalTrials.gov
NCT06356194 Drug-drug Interaction Study of Biktarvy and Bemnifosbuvir/Ruzasvir Phase1 Healthy Volunteer Study Completed 2024-04-15 2024-05-30 ClinicalTrials.gov
NCT06204679 Pharmacokinetics of Fixed-Dose Combination Tablet of Bemnifosbuvir and Ruzasvir Phase1 Healthy Volunteer Study Completed 2023-12-14 2024-08-25 ClinicalTrials.gov
NCT05904470 A Phase 2, Safety and Efficacy of Bemnifosbuvir (BEM) and Ruzasvir (RZR) in Sub… Phase2 Chronic Hepatitis C Virus Completed 2023-05-30 2025-01-28 ClinicalTrials.gov
NCT05905497 The Study of Bemnifosbuvir in Healthy Japanese Subjects Phase1 Healthy Volunteer Study Completed 2023-04-26 2023-05-19 ClinicalTrials.gov
NCT05905484 Study of Bemnifosbuvir on Cardiac Repolarization in Healthy Subjects Phase1 Healthy Volunteer Study Completed 2023-04-25 2023-05-31 ClinicalTrials.gov
NCT05731843 Drug-drug Interaction Study of Ruzasvir and Bemnifosbuvir Phase1 Healthy Volunteer Study Completed 2023-01-30 2023-03-15 ClinicalTrials.gov
NCT05724693 Study of Bemnifosbuvir in Subjects With Normal and Impaired Hepatic Function Phase1 Healthy Volunteer Completed 2023-01-30 2024-04-23 ClinicalTrials.gov
NCT05629962 SUNRISE-3: Efficacy and Safety of Bemnifosbuvir in High-Risk Outpatients With C… Phase3 Severe Acute Respiratory Syndrome Coronavirus 2 (SARS CoV 2 Infection) Completed 2022-11-25 2024-05-30 ClinicalTrials.gov
NCT05618314 Study of AT-527 in Subjects With Normal and Impaired Renal Function Phase1 Healthy Volunteer Completed 2022-10-17 2024-06-15 ClinicalTrials.gov
NCT05466240 Study of AT-752 in Patients With Dengue Infection Phase2 Dengue Fever Terminated 2022-04-29 2023-01-19 ClinicalTrials.gov
NCT05366439 Study of AT-752 in Healthy Subjects in a Dengue Human Challenge Model Phase1 Dengue Terminated 2022-04-22 2023-03-16 ClinicalTrials.gov
NCT05256732 Study of AT-527 in Healthy Subjects Under Fasting Conditions or With a Meal Phase1 Healthy Volunteer Study Completed 2022-02-22 2022-08-23 ClinicalTrials.gov
NCT05154123 Drug-drug Interaction Study of Rosuvastatin and AT-527 (R07496998) Phase1 Healthy Volunteer Study Completed 2021-11-16 2021-12-23 ClinicalTrials.gov
NCT05137626 Drug-drug Interaction Study of Digoxin and AT-527 (R07496998) Phase1 Healthy Volunteers Study Completed 2021-11-03 2021-12-12 ClinicalTrials.gov
NCT04309734 Study of AT-777 in Healthy Subjects and AT-777 in Combination With AT-527 in HC… Phase1 Hepatitis C Withdrawn 2021-10-01 2022-09-01 ClinicalTrials.gov
NCT05004415 Mass Balance Study of AT-527 in Healthy Adult Male Subjects (R07496998) Phase1 Healthy Volunteer Study Completed 2021-07-28 2021-08-12 ClinicalTrials.gov
NCT05059080 A Six-Month Follow-Up Study of Participants With Coronavirus Disease 2019 (COVI… COVID-19 Terminated 2021-06-15 2022-03-16 ClinicalTrials.gov
NCT04889040 Study to Evaluate the Effects of RO7496998 (AT-527) in Non-Hospitalized Adult a… Phase3 COVID-19 Terminated 2021-04-28 2021-12-02 ClinicalTrials.gov
NCT04877769 Bronchopulmonary PK of AT-527 (R07496998) Phase1 Healthy Volunteer Study Completed 2021-04-25 2021-08-31 ClinicalTrials.gov
NCT04865445 Drug-drug Interaction Study of Midazolam and AT-527 (R07496998) Phase1 Healthy Volunteer Study Completed 2021-04-22 2021-05-15 ClinicalTrials.gov
NCT04849299 Effect of Cyclosporine on the Pharmacokinetics (PK) of AT-527 (R07496998) Phase1 Healthy Volunteer Study Completed 2021-04-18 2021-05-10 ClinicalTrials.gov
NCT04722627 Study of AT-752 in Healthy Subjects Phase1 Dengue Completed 2021-03-09 2021-11-14 ClinicalTrials.gov
NCT04784000 Effect of Carbamazepine on the Pharmacokinetics (PK) of AT-527 Phase1 Healthy Volunteer Study Completed 2021-03-01 2021-04-10 ClinicalTrials.gov
NCT04709835 Study to Evaluate the Effects of AT-527 in Non-Hospitalized Adult Patients With… Phase2 COVID-19 Completed 2021-02-03 2021-10-13 ClinicalTrials.gov
NCT04711187 Study of AT-527 in Healthy Subjects (R07496998) Phase1 Healthy Volunteer Study Completed 2020-11-02 2021-09-15 ClinicalTrials.gov
NCT04396106 Safety and Efficacy of AT-527 in Subjects With Moderate Coronavirus Disease (CO… Phase2 COVID-19 Terminated 2020-05-26 2022-02-28 ClinicalTrials.gov
NCT04019717 Study of AT-527 in Combination With Daclatasvir in Subjects With Hepatitis C Vi… Phase2 Hepatitis C Completed 2019-06-20 2020-03-23 ClinicalTrials.gov
NCT03219957 Study of AT-527 in Healthy and HCV-Infected Subjects Phase1 Chronic Hepatitis C Completed 2017-07-06 2018-06-20 ClinicalTrials.gov
Total clinical trials: 35
Product Name Type Development Stage Therapeutic Area Study Status Trial ID
Methadone +BEM/RZR Other Phase PHASE1 Healthy Volunteer Study RECRUITING NCT07314346
Buprenorphine/Naloxone + BEM/RZR Other Phase PHASE1 Healthy Volunteer Study RECRUITING NCT07314346
Sofosbuvir-Velpatasvir Other Phase PHASE3 HEPATITIS C VIRUS CHRONIC INFECTION ACTIVE_NOT_RECRUITING NCT07037277
Bemnifosbuvir-Ruzasvir Other Phase PHASE3 HEPATITIS C VIRUS CHRONIC INFECTION ACTIVE_NOT_RECRUITING NCT07037277
AT-527 + rosuvastatin Other Phase PHASE1 Healthy Volunteer Study COMPLETED NCT05154123
Drug: AT-527 + rosuvastatin Drug Phase PHASE1 Healthy Volunteer Study COMPLETED NCT05154123
AT-527 (R07496998) Other Phase PHASE1 Healthy Volunteer Study COMPLETED NCT05004415
Treatment F-Bemnifosbuvir/Ruzasvir FDC administered 2 hours after 40 mg dose Omeprazole Drug Phase PHASE1 Healthy Volunteer Study COMPLETED NCT07007806
Treatment E-Omeprazole 40 mg administered fasting Drug Phase PHASE1 Healthy Volunteer Study COMPLETED NCT07007806
Treatment D-Bemnifosbuvir/Ruzasvir FDC administered 0.5 hour prior to 20 mg dose of Omeprazole Drug Phase PHASE1 Healthy Volunteer Study COMPLETED NCT07007806
Treatment C-Bemnifosbuvir/Ruzasvir FDC administered simultaneously with 20 mg dose of Omeprazole fasting Drug Phase PHASE1 Healthy Volunteer Study COMPLETED NCT07007806
Treatment B-Omeprazole 20 mg dose administered fasting Drug Phase PHASE1 Healthy Volunteer Study COMPLETED NCT07007806
Treatment A-Bemnifosbuvir/Ruzasvir FDC administered fasting Drug Phase PHASE1 Healthy Volunteer Study COMPLETED NCT07007806
Placebo Comparator Other Phase PHASE1 Chronic Hepatitis C COMPLETED NCT03219957
AT-527 Other Phase PHASE1 Chronic Hepatitis C COMPLETED NCT03219957
Daclatasvir Other Phase PHASE2 Hepatitis C COMPLETED NCT04019717
AT-527 Other Phase PHASE2 Hepatitis C COMPLETED NCT04019717
AT-527 550 mg + midazolam Other Phase PHASE1 Healthy Volunteer Study COMPLETED NCT04865445
Period 3: AT-527 1100 mg + carbamazepine Other Phase PHASE1 Healthy Volunteer Study COMPLETED NCT04784000
Period 3: AT-527 550 mg + carbamazepine Other Phase PHASE1 Healthy Volunteer Study COMPLETED NCT04784000
Period 2: carbamazepine Other Phase PHASE1 Healthy Volunteer Study COMPLETED NCT04784000
Period 1: AT-527 550 mg Other Phase PHASE1 Healthy Volunteer Study COMPLETED NCT04784000
AT-527 550 mg + cyclosporine Other Phase PHASE1 Healthy Volunteer Study COMPLETED NCT04849299
AT-527 Other Phase PHASE1 Healthy Volunteer Study COMPLETED NCT04877769
AT-527 Formulation 2 Other Phase PHASE1 Healthy Volunteer Study COMPLETED NCT04711187
Placebo Comparator Other Phase PHASE1 Healthy Volunteer Study COMPLETED NCT04711187
AT-527 Formulation 1 Other Phase PHASE1 Healthy Volunteer Study COMPLETED NCT04711187
AT-527 + digoxin Other Phase PHASE1 Healthy Volunteers Study COMPLETED NCT05137626
AT-527 Other Phase PHASE1 Hepatitis C WITHDRAWN NCT04309734
Placebo Other Phase PHASE1 Hepatitis C WITHDRAWN NCT04309734
AT-777 Other Phase PHASE1 Hepatitis C WITHDRAWN NCT04309734
Placebo Other Phase PHASE1 Dengue COMPLETED NCT04722627
AT-752 Other Phase PHASE1 Dengue COMPLETED NCT04722627
AT-527 single dose Other Phase PHASE1 Healthy Volunteer Study COMPLETED NCT05256732
AT-527 Other Phase PHASE1 Healthy Volunteer Study COMPLETED NCT05256732
Placebo Comparator fed Other Phase PHASE1 Healthy Volunteer Study COMPLETED NCT05256732
AT-527 fed Other Phase PHASE1 Healthy Volunteer Study COMPLETED NCT05256732
Placebo Comparator fasted Other Phase PHASE1 Healthy Volunteer Study COMPLETED NCT05256732
AT-527 fasted Other Phase PHASE1 Healthy Volunteer Study COMPLETED NCT05256732
Placebo Other Phase PHASE2 COVID-19 COMPLETED NCT04709835
AT-527 Other Phase PHASE2 COVID-19 COMPLETED NCT04709835
Placebo Other Phase PHASE2 COVID-19 TERMINATED NCT04396106
AT-527 Other Phase PHASE2 COVID-19 TERMINATED NCT04396106
Placebo Comparator Other Phase PHASE1 Dengue TERMINATED NCT05366439
AT-752 Other Phase PHASE1 Dengue TERMINATED NCT05366439
Cohort 2 Ruzasvir + BEM Other Phase PHASE1 Healthy Volunteer Study COMPLETED NCT05731843
Cohort 1 BEM + Ruzasvir Other Phase PHASE1 Healthy Volunteer Study COMPLETED NCT05731843
Bemnifosbuvir (BEM) Other Phase PHASE1 Healthy Volunteer Study COMPLETED NCT05905497
Moxifloxacin Other Phase PHASE1 Healthy Volunteer Study COMPLETED NCT05905484
Placebo Other Phase PHASE1 Healthy Volunteer Study COMPLETED NCT05905484
Bemnifosbuvir (BEM) Other Phase PHASE1 Healthy Volunteer Study COMPLETED NCT05905484
Placebo Other Phase PHASE3 COVID-19 TERMINATED NCT04889040
RO7496998 Other Phase PHASE3 COVID-19 TERMINATED NCT04889040
Placebo Other Phase PHASE2 Dengue Fever TERMINATED NCT05466240
AT-752 Other Phase PHASE2 Dengue Fever TERMINATED NCT05466240
Cohort 2: Days 1-10 Biktarvy (BIK). Days 11-17 Bemnifosbuvir (BEM)/Ruzasvir (RZR) co-administered + Biktarvy (BIK). Days 18-24 Bemnifosbuvir (BEM)/Ruzasvir (RZR) co-administered. Other Phase PHASE1 Healthy Volunteer Study COMPLETED NCT06356194
Cohort 1: Days 1-7 Bemnifosbuvir (BEM)/Ruzasvir (RZR) co-administered. Days 8-17 Bemnifosbuvir (BEM)/Ruzasvir (RZR) co-administered + Biktarvy (BIK). Days 18-24 BIK Other Phase PHASE1 Healthy Volunteer Study COMPLETED NCT06356194
Bemnifosbuvir (BEM) Other Phase PHASE1 Healthy Volunteer COMPLETED NCT05724693
AT-527 and Probenecid Other Phase PHASE1 Healthy Volunteer COMPLETED NCT05618314
AT-527 Other Phase PHASE1 Healthy Volunteer COMPLETED NCT05618314
Bemnifosbuvir (BEM) and Ruzasvir (RZR) as reference formulation under fasting conditions Other Phase PHASE1 Healthy Volunteer Study COMPLETED NCT06204679
Bemnifosbuvir (BEM)/Ruzasvir (RZR) FDC under fed conditions Other Phase PHASE1 Healthy Volunteer Study COMPLETED NCT06204679
Bemnifosbuvir (BEM)/Ruzasvir (RZR) FDC under fasting conditions Other Phase PHASE1 Healthy Volunteer Study COMPLETED NCT06204679
Placebo Other Phase PHASE3 Severe Acute Respiratory Syndrome Coronavirus 2 (SARS CoV 2 Infection) COMPLETED NCT05629962
Bemnifosbuvir (BEM) Other Phase PHASE3 Severe Acute Respiratory Syndrome Coronavirus 2 (SARS CoV 2 Infection) COMPLETED NCT05629962
Rosuvastatin vs Rosuvastatin + BEM/RZR vs Rosuvastatin + 2h BEM/RZR Other Phase PHASE1 Healthy Volunteer Study COMPLETED NCT06921941
Digoxin vs Digoxin + BEM/RZR vs Digoxin + 2h BEM/RZR Other Phase PHASE1 Healthy Volunteer Study COMPLETED NCT06921941
Methadone +BEM/RZR Other Phase PHASE1 Healthy Volunteer Study RECRUITING NCT07314346
Buprenorphine/Naloxone + BEM/RZR Other Phase PHASE1 Healthy Volunteer Study RECRUITING NCT07314346
Sofosbuvir-Velpatasvir Other Phase PHASE3 HEPATITIS C VIRUS CHRONIC INFECTION RECRUITING NCT07037277
Bemnifosbuvir-Ruzasvir Other Phase PHASE3 HEPATITIS C VIRUS CHRONIC INFECTION RECRUITING NCT07037277
Ruzasvir Other Phase PHASE2 Chronic Hepatitis C Virus COMPLETED NCT05904470
Bemnifosbuvir Other Phase PHASE2 Chronic Hepatitis C Virus COMPLETED NCT05904470
Sofosbuvir-Velpatasvir (SOF/VEL) Other Phase PHASE3 HEPATITIS C VIRUS CHRONIC INFECTION ACTIVE_NOT_RECRUITING NCT06868264
Bemnifosbuvir-Ruzasvir (BEM/RZR) Other Phase PHASE3 HEPATITIS C VIRUS CHRONIC INFECTION ACTIVE_NOT_RECRUITING NCT06868264
Bemnifosbuvir/Ruzasvir (BEM/RZR) + Ethinyl Estradioll/Levonorgestrel (EE/LNG) Other Phase PHASE1 Healthy Volunteer Study COMPLETED NCT07272889
Bemnifosbuvir/Ruzasvir (BEM/RZR) Other Phase PHASE1 Healthy Volunteer Study COMPLETED NCT07272889
Ethinyl Estradioll/Levonorgestrel (EE/LNG) Other Phase PHASE1 Healthy Volunteer Study COMPLETED NCT07272889
Bemnifosbuvir (BEM)/Ruzasvir (RZR) as a fixed-dose combination Other Phase PHASE1 Healthy Volunteer Study RECRUITING NCT06911320
Citrate buffer DRUG Phase PHASE1 Healthy COMPLETED NCT00698425
EyeGate II® Drug Delivery System OTHER Phase PHASE1 Healthy COMPLETED NCT00698425
Sodium citrate buffer solution with EyeGate® II System DRUG Phase PHASE2 Dry Eye Syndrome COMPLETED NCT00765804
EGP-437 with EyeGate® II System DRUG Phase PHASE2 Dry Eye Syndrome COMPLETED NCT00765804
EGP-437 14.0 mA-min at 3.5 mA with EyeGate® II System DRUG Phase PHASE2 Uveitis, Anterior COMPLETED NCT00694135
EGP-437 10.0 mA-min at 2.5 mA with EyeGate® II System DRUG Phase PHASE2 Uveitis, Anterior COMPLETED NCT00694135
EGP-437 4.8 mA-min at 1.2 mA with EyeGate® II System DRUG Phase PHASE2 Uveitis, Anterior COMPLETED NCT00694135
EGP-437 1.6 mA-min at 0.4 with EyeGate® II System DRUG Phase PHASE2 Uveitis, Anterior COMPLETED NCT00694135
Sodium citrate buffer solution DRUG Phase PHASE3 Dry Eye COMPLETED NCT01129856
Dexamethasone phosphate ophthalmic solution DRUG Phase PHASE3 Dry Eye COMPLETED NCT01129856
Placebo Eyedrops DRUG Phase PHASE3 Anterior Uveitis COMPLETED NCT01505088
100 mM sodium citrate buffer solution DRUG Phase PHASE3 Anterior Uveitis COMPLETED NCT01505088
Prednisolone Acetate (1%) Eyedrops DRUG Phase PHASE3 Anterior Uveitis COMPLETED NCT01505088
40 mg/mL Dexamethasone phosphate ophthalmic solution DRUG Phase PHASE3 Anterior Uveitis COMPLETED NCT01505088
Experimental: Dexamethasone Phosphate Ophthalmic solution (40 mg/mL) delivered by ocular iontophoresis consisting of 4.0 mA-min at 1.5 mA DRUG Phase PHASE1 Patients Having Undergone Unilateral Cataract Extraction and Implantation of a Monofocal COMPLETED NCT02571556
Dexamethasone Phosphate Ophthalmic Solution DRUG Phase PHASE1 Vitrectomy COMPLETED NCT02644694
100 mM Sodium Citrate Buffer DRUG Phase PHASE2 Cataract COMPLETED NCT01602068
Dexamethasone Phosphate Ophthalmic DRUG Phase PHASE1 Macular Edema TERMINATED NCT02485249
Bandage Contact Lens (BCL) DEVICE Approved Ophthalmology COMPLETED NCT03938883
Ocular Bandage Gel (OBG) DEVICE Approved Ophthalmology COMPLETED NCT03938883
Nitrofurantoin capsules DRUG Phase PHASE2 Uncomplicated Urinary Tract Infection COMPLETED NCT03425396
Omadacycline tablets DRUG Phase PHASE2 Uncomplicated Urinary Tract Infection COMPLETED NCT03425396
Levofloxacin DRUG Phase PHASE2 Acute Pyelonephritis COMPLETED NCT03757234
Linezolid DRUG Phase PHASE3 Skin Structures and Soft Tissue Infections WITHDRAWN NCT00876850
PTK 0796 DRUG Phase PHASE3 Skin Structures and Soft Tissue Infections WITHDRAWN NCT00876850
Ocular Bandage Gel DEVICE Approved Corneal Epithelial Wound COMPLETED NCT03163641
Acuvue Oasys DEVICE Approved Corneal Epithelial Wound COMPLETED NCT03163641
Microdialysis Catheter Insertion PROCEDURE Phase PHASE1 Diabetes COMPLETED NCT04144374
Placebos DRUG Phase PHASE3 Migraine COMPLETED NCT03901482
Dihydroergotamine DRUG Phase PHASE1 Migraine With Aura COMPLETED NCT03874832
Omadacycline Oral Tablet [Nuzyra] DRUG Phase PHASE4 Cystic Fibrosis COMPLETED NCT04460586
Omadacycline Injection DRUG Phase PHASE4 Microbial Colonization COMPLETED NCT05515562
Vancomycin Pill DRUG Phase PHASE1 Healthy Volunteers COMPLETED NCT06030219
Omadacycline DRUG Phase PHASE3 Bacterial Pneumonia COMPLETED NCT02531438
Omadacycline Oral Tablet DRUG Phase PHASE2 Mycobacterium Infections, Nontuberculous COMPLETED NCT04922554
Omadacycline Injection [Nuzyra] DRUG Phase PHASE4 Cystic Fibrosis COMPLETED NCT04460586
NP-101 DRUG Phase PHASE1 Solid Tumor RECRUITING NCT06563375
Methadone +BEM/RZR DRUG Phase PHASE1 Healthy Volunteer Study NOT_YET_RECRUITING NCT07314346
Buprenorphine/Naloxone + BEM/RZR DRUG Phase PHASE1 Healthy Volunteer Study NOT_YET_RECRUITING NCT07314346
Bemnifosbuvir/Ruzasvir (BEM/RZR) + Ethinyl Estradioll/Levonorgestrel (EE/LNG) DRUG Phase PHASE1 Healthy Volunteer Study NOT_YET_RECRUITING NCT07272889
Bemnifosbuvir/Ruzasvir (BEM/RZR) DRUG Phase PHASE1 Healthy Volunteer Study NOT_YET_RECRUITING NCT07272889
Ethinyl Estradioll/Levonorgestrel (EE/LNG) DRUG Phase PHASE1 Healthy Volunteer Study NOT_YET_RECRUITING NCT07272889
Sofosbuvir-Velpatasvir DRUG Phase PHASE3 HEPATITIS C VIRUS CHRONIC INFECTION RECRUITING NCT07037277
Bemnifosbuvir-Ruzasvir DRUG Phase PHASE3 HEPATITIS C VIRUS CHRONIC INFECTION RECRUITING NCT07037277
Treatment F-Bemnifosbuvir/Ruzasvir FDC administered 2 hours after 40 mg dose Omeprazole DRUG Phase PHASE1 Healthy Volunteer Study COMPLETED NCT07007806
Treatment E-Omeprazole 40 mg administered fasting DRUG Phase PHASE1 Healthy Volunteer Study COMPLETED NCT07007806
Treatment D-Bemnifosbuvir/Ruzasvir FDC administered 0.5 hour prior to 20 mg dose of Omeprazole DRUG Phase PHASE1 Healthy Volunteer Study COMPLETED NCT07007806
Treatment C-Bemnifosbuvir/Ruzasvir FDC administered simultaneously with 20 mg dose of Omeprazole fasting DRUG Phase PHASE1 Healthy Volunteer Study COMPLETED NCT07007806
Treatment B-Omeprazole 20 mg dose administered fasting DRUG Phase PHASE1 Healthy Volunteer Study COMPLETED NCT07007806
Treatment A-Bemnifosbuvir/Ruzasvir FDC administered fasting DRUG Phase PHASE1 Healthy Volunteer Study COMPLETED NCT07007806
Rosuvastatin vs Rosuvastatin + BEM/RZR vs Rosuvastatin + 2h BEM/RZR DRUG Phase PHASE1 Healthy Volunteer Study COMPLETED NCT06921941
Digoxin vs Digoxin + BEM/RZR vs Digoxin + 2h BEM/RZR DRUG Phase PHASE1 Healthy Volunteer Study COMPLETED NCT06921941
Bemnifosbuvir (BEM)/Ruzasvir (RZR) as a fixed-dose combination DRUG Phase PHASE1 Healthy Volunteer Study RECRUITING NCT06911320
Sofosbuvir-Velpatasvir (SOF/VEL) DRUG Phase PHASE3 HEPATITIS C VIRUS CHRONIC INFECTION ACTIVE_NOT_RECRUITING NCT06868264
Bemnifosbuvir-Ruzasvir (BEM/RZR) DRUG Phase PHASE3 HEPATITIS C VIRUS CHRONIC INFECTION ACTIVE_NOT_RECRUITING NCT06868264
Cohort 2: Days 1-10 Biktarvy (BIK). Days 11-17 Bemnifosbuvir (BEM)/Ruzasvir (RZR) co-administered + Biktarvy (BIK). Days 18-24 Bemnifosbuvir (BEM)/Ruzasvir (RZR) co-administered. DRUG Phase PHASE1 Healthy Volunteer Study COMPLETED NCT06356194
Cohort 1: Days 1-7 Bemnifosbuvir (BEM)/Ruzasvir (RZR) co-administered. Days 8-17 Bemnifosbuvir (BEM)/Ruzasvir (RZR) co-administered + Biktarvy (BIK). Days 18-24 BIK DRUG Phase PHASE1 Healthy Volunteer Study COMPLETED NCT06356194
Bemnifosbuvir (BEM) and Ruzasvir (RZR) as reference formulation under fasting conditions DRUG Phase PHASE1 Healthy Volunteer Study COMPLETED NCT06204679
Bemnifosbuvir (BEM)/Ruzasvir (RZR) FDC under fed conditions DRUG Phase PHASE1 Healthy Volunteer Study COMPLETED NCT06204679
Bemnifosbuvir (BEM)/Ruzasvir (RZR) FDC under fasting conditions DRUG Phase PHASE1 Healthy Volunteer Study COMPLETED NCT06204679
Moxifloxacin DRUG Phase PHASE3 Bacterial Pneumonia COMPLETED NCT02531438
Ruzasvir DRUG Phase PHASE2 Chronic Hepatitis C Virus COMPLETED NCT05904470
Bemnifosbuvir DRUG Phase PHASE2 Chronic Hepatitis C Virus COMPLETED NCT05904470
Cohort 2 Ruzasvir + BEM DRUG Phase PHASE1 Healthy Volunteer Study COMPLETED NCT05731843
Cohort 1 BEM + Ruzasvir DRUG Phase PHASE1 Healthy Volunteer Study COMPLETED NCT05731843
Bemnifosbuvir (BEM) DRUG Phase PHASE1 Healthy Volunteer Study COMPLETED NCT05905497
AT-527 and Probenecid DRUG Phase PHASE1 Healthy Volunteer COMPLETED NCT05618314
AT-527 single dose DRUG Phase PHASE1 Healthy Volunteer Study COMPLETED NCT05256732
Placebo Comparator fed OTHER Phase PHASE1 Healthy Volunteer Study COMPLETED NCT05256732
AT-527 fed DRUG Phase PHASE1 Healthy Volunteer Study COMPLETED NCT05256732
Placebo Comparator fasted OTHER Phase PHASE1 Healthy Volunteer Study COMPLETED NCT05256732
AT-527 fasted DRUG Phase PHASE1 Healthy Volunteer Study COMPLETED NCT05256732
AT-527 + rosuvastatin DRUG Phase PHASE1 Healthy Volunteer Study COMPLETED NCT05154123
Drug: AT-527 + rosuvastatin DRUG Phase PHASE1 Healthy Volunteer Study COMPLETED NCT05154123
AT-527 + digoxin DRUG Phase PHASE1 Healthy Volunteers Study COMPLETED NCT05137626
AT-527 (R07496998) DRUG Phase PHASE1 Healthy Volunteer Study COMPLETED NCT05004415
RO7496998 DRUG Phase PHASE3 COVID-19 TERMINATED NCT04889040
AT-527 550 mg + midazolam DRUG Phase PHASE1 Healthy Volunteer Study COMPLETED NCT04865445
AT-527 550 mg + cyclosporine DRUG Phase PHASE1 Healthy Volunteer Study COMPLETED NCT04849299
Period 3: AT-527 1100 mg + carbamazepine DRUG Phase PHASE1 Healthy Volunteer Study COMPLETED NCT04784000
Period 3: AT-527 550 mg + carbamazepine DRUG Phase PHASE1 Healthy Volunteer Study COMPLETED NCT04784000
Period 2: carbamazepine DRUG Phase PHASE1 Healthy Volunteer Study COMPLETED NCT04784000
Period 1: AT-527 550 mg DRUG Phase PHASE1 Healthy Volunteer Study COMPLETED NCT04784000
AT-752 DRUG Phase PHASE2 Dengue Fever TERMINATED NCT05466240
AT-527 Formulation 2 DRUG Phase PHASE1 Healthy Volunteer Study COMPLETED NCT04711187
AT-527 Formulation 1 DRUG Phase PHASE1 Healthy Volunteer Study COMPLETED NCT04711187
Placebo OTHER Phase PHASE2 Cataract COMPLETED NCT03180255
AT-777 DRUG Phase PHASE1 Hepatitis C WITHDRAWN NCT04309734
Daclatasvir DRUG Phase PHASE2 Hepatitis C COMPLETED NCT04019717
Placebo Comparator DRUG Phase PHASE1 Dengue TERMINATED NCT05366439
AT-527 DRUG Phase PHASE1 Healthy Volunteer COMPLETED NCT05618314
Total products: 170