SymbolATYR
NameATYR PHARMA INC
SectorHEALTH CARE
RegionNorth America
IndustryBiological Products, (No Diagnostic Substances)
Address10240 SORRENTO VALLEY ROAD, SAN DIEGO, CA 92121
Telephone8587318389
Fax
Email
Websitehttps://www.atyrpharma.com
IncorporationUNDEFINED
Incorporated On
Employees
Fiscal Year
Public Since
ExchangesNASDAQ
Auditor
Audit StatusNOT PROVIDED
Reporting Status
CIK0001339970
Description

aTyr Pharma Inc is a biotherapeutics company engaged in the discovery and development of innovative medicines based on novel immunological pathways. Its focus is on the extracellular functionality and signaling pathways of tRNA synthetases. Its lead clinical product candidate, ATYR1923, is a selective modulator of Neuropilin-2 (NRP2) that downregulates both the innate and adaptive immune responses in inflammatory disease states. It is developing ATYR1923 as a potential disease-modifying therapy for patients with interstitial lung diseases (ILDs), a group of rare immune-mediated disorders that cause progressive fibrosis of the lung interstitium and remain a high unmet medical need.

Additional info from NASDAQ:
aTyr Pharma Inc is a biotherapeutics company engaged in the discovery and development of innovative medicines based on novel immunological pathways. Its focus is on the extracellular functionality and signaling pathways of tRNA synthetases. Its lead clinical product candidate, ATYR1923, is a selective modulator of Neuropilin-2 (NRP2) that downregulates both the innate and adaptive immune responses in inflammatory disease states. It is developing ATYR1923 as a potential disease-modifying therapy for patients with interstitial lung diseases (ILDs), a group of rare immune-mediated disorders that cause progressive fibrosis of the lung interstitium and remain a high unmet medical need.

2026-07-15 12:00

aTyr Pharma to Present Subgroup Analysis of Phase 3 EFZO-FIT™ Study of Efzofitimod in Pulmonary Sarcoidosis at WASOG 2026

Read more
2026-07-08 08:38

New Form SCHEDULE 13G/A - aTYR PHARMA INC <b>Filed:</b> 2026-07-08 <b>AccNo:</b> 0001623632-26-000980 <b>Size:</b> 46 KB

Read more
2026-06-05 11:13

New Form SCHEDULE 13G/A - aTYR PHARMA INC <b>Filed:</b> 2026-06-05 <b>AccNo:</b> 0000315066-26-001409 <b>Size:</b> 11 KB

Read more
2026-05-15 12:02

(10% Negative) ATYR PHARMA INC (ATYR) Reports Q2 2026 Financial Results

Read more
2026-05-15 12:00

aTyr Pharma Announces First Quarter 2026 Results and Provides Corporate Update

Read more
2026-05-13 20:17

Coughlin Timothy 🟢 acquired 50.0K shares (1 derivative) of aTYR PHARMA INC (ATYR) at $0.95 Transaction Date: May 11, 2026 | Filing ID: 000003

Read more
2026-05-13 20:15

BENEVICH ERIC 🟢 acquired 50.0K shares (1 derivative) of aTYR PHARMA INC (ATYR) at $0.95 Transaction Date: May 11, 2026 | Filing ID: 000014

Read more
2026-05-13 20:14

Gross Jane A 🟢 acquired 50.0K shares (1 derivative) of aTYR PHARMA INC (ATYR) at $0.95 Transaction Date: May 11, 2026 | Filing ID: 000003

Read more
2026-05-13 20:12

Lucas Svetlana 🟢 acquired 50.0K shares (1 derivative) of aTYR PHARMA INC (ATYR) at $0.95 Transaction Date: May 11, 2026 | Filing ID: 000003

Read more
2026-05-13 20:10

Zaknoen Sara 🟢 acquired 50.0K shares (1 derivative) of aTYR PHARMA INC (ATYR) at $0.95 Transaction Date: May 11, 2026 | Filing ID: 000003

Read more
Trial ID Title Phase Indication Status Start Date Completion Date Source
NCT05892614 Study to Evaluate the Efficacy, Safety, and Tolerability of Efzofitimod in Pati… Phase2 Interstitial Lung Disease Recruiting 2023-10-26 2026-04-01 ClinicalTrials.gov
NCT05415137 Efficacy and Safety of Intravenous Efzofitimod in Patients With Pulmonary Sarco… Phase3 Pulmonary Sarcoidosis Completed 2022-09-15 2025-07-14 ClinicalTrials.gov
NCT04412668 Study to Evaluate the Safety and Efficacy of ATYR1923 (Efzofitimod) In Particip… Phase2 SARS-CoV-2 (COVID-19) Severe Pneumonia Completed 2020-06-04 2020-10-23 ClinicalTrials.gov
NCT03824392 Study of Intravenous ATYR1923 (Efzofitimod) for Pulmonary Sarcoidosis Phase1 Pulmonary Sarcoidosis Completed 2019-01-29 2021-06-29 ClinicalTrials.gov
NCT02836418 Study to Evaluate the Long-Term Safety, Tolerability, and Biological Activity o… Phase1 Facioscapulohumeral Muscular Dystrophy Completed 2016-07-13 2017-04-18 ClinicalTrials.gov
NCT02603562 Evaluate Safety and Biological Activity of ATYR1940 in Participants With Early … Phase1 Facioscapulohumeral Muscular Dystrophy (FSHD) Completed 2016-03-30 2016-12-12 ClinicalTrials.gov
NCT02579239 Evaluate Safety and Biological Activity of ATYR1940 in Participants With Limb G… Phase1 Limb-Girdle Muscular Dystrophies Completed 2015-11-30 2016-10-05 ClinicalTrials.gov
NCT02531217 Safety, Tolerability, Pharmacokinetics (PK), and Activity of ATYR1940 in Partic… Phase1 Facioscapulohumeral Muscular Dystrophy Completed 2015-08-13 2016-05-26 ClinicalTrials.gov
NCT02239224 Safety, Tolerability, Pharmacokinetics, and Biological Activity of ATYR1940 in … Phase1 Facioscapulohumeral Muscular Dystrophy (FSHD) Completed 2014-09-04 2015-12-14 ClinicalTrials.gov
NCT01437345 A Multicenter Collaborative Study on the Clinical Features, Expression Profilin… Facioscapulohumeral Muscular Dystrophy Completed 2012-07-01 2017-08-01 ClinicalTrials.gov
Total clinical trials: 10
Product Name Type Development Stage Therapeutic Area Study Status Trial ID
Placebo Other Phase PHASE3 Pulmonary Sarcoidosis COMPLETED NCT05415137
Efzofitimod 5 mg/kg Other Phase PHASE3 Pulmonary Sarcoidosis COMPLETED NCT05415137
Efzofitimod 3 mg/kg Other Phase PHASE3 Pulmonary Sarcoidosis COMPLETED NCT05415137
ATYR1940 Other Phase PHASE1 Facioscapulohumeral Muscular Dystrophy (FSHD) COMPLETED NCT02239224
Placebo Other Phase PHASE1 Facioscapulohumeral Muscular Dystrophy (FSHD) COMPLETED NCT02239224
Efzofitimod 5.0 mg/kg or Placebo Other Phase PHASE1 Pulmonary Sarcoidosis COMPLETED NCT03824392
Efzofitimod 3.0 mg/kg or Placebo Other Phase PHASE1 Pulmonary Sarcoidosis COMPLETED NCT03824392
Efzofitimod 1.0 mg/kg or Placebo Other Phase PHASE1 Pulmonary Sarcoidosis COMPLETED NCT03824392
Placebo Other Phase PHASE2 SARS-CoV-2 (COVID-19) Severe Pneumonia COMPLETED NCT04412668
Efzofitimod 3 mg/kg Other Phase PHASE2 SARS-CoV-2 (COVID-19) Severe Pneumonia COMPLETED NCT04412668
Efzofitimod 1 mg/kg Other Phase PHASE2 SARS-CoV-2 (COVID-19) Severe Pneumonia COMPLETED NCT04412668
ATYR1940 Other Phase PHASE1 Facioscapulohumeral Muscular Dystrophy COMPLETED NCT02531217
ATYR1940 Other Phase PHASE1 Facioscapulohumeral Muscular Dystrophy (FSHD) COMPLETED NCT02603562
Placebo Other Phase PHASE1 Limb-Girdle Muscular Dystrophies COMPLETED NCT02579239
ATYR1940 Other Phase PHASE1 Limb-Girdle Muscular Dystrophies COMPLETED NCT02579239
ATYR1940 Other Phase PHASE1 Facioscapulohumeral Muscular Dystrophy COMPLETED NCT02836418
Placebo Other Phase PHASE2 Interstitial Lung Disease RECRUITING NCT05892614
efzofitimod 270 mg Other Phase PHASE2 Interstitial Lung Disease RECRUITING NCT05892614
efzofitimod 450 mg Other Phase PHASE2 Interstitial Lung Disease RECRUITING NCT05892614
Placebo Other Phase PHASE3 Pulmonary Sarcoidosis ACTIVE_NOT_RECRUITING NCT05415137
Efzofitimod 5 mg/kg Other Phase PHASE3 Pulmonary Sarcoidosis ACTIVE_NOT_RECRUITING NCT05415137
Efzofitimod 3 mg/kg Other Phase PHASE3 Pulmonary Sarcoidosis ACTIVE_NOT_RECRUITING NCT05415137
efzofitimod 270 mg DRUG Phase PHASE2 Interstitial Lung Disease RECRUITING NCT05892614
efzofitimod 450 mg DRUG Phase PHASE2 Interstitial Lung Disease RECRUITING NCT05892614
Efzofitimod 5 mg/kg DRUG Phase PHASE3 Pulmonary Sarcoidosis ACTIVE_NOT_RECRUITING NCT05415137
Efzofitimod 3 mg/kg DRUG Phase PHASE3 Pulmonary Sarcoidosis ACTIVE_NOT_RECRUITING NCT05415137
Efzofitimod 1 mg/kg DRUG Phase PHASE2 SARS-CoV-2 (COVID-19) Severe Pneumonia COMPLETED NCT04412668
Efzofitimod 5.0 mg/kg or Placebo BIOLOGICAL Phase PHASE1 Pulmonary Sarcoidosis COMPLETED NCT03824392
Efzofitimod 3.0 mg/kg or Placebo BIOLOGICAL Phase PHASE1 Pulmonary Sarcoidosis COMPLETED NCT03824392
Efzofitimod 1.0 mg/kg or Placebo BIOLOGICAL Phase PHASE1 Pulmonary Sarcoidosis COMPLETED NCT03824392
ATYR1940 DRUG Phase PHASE1 Facioscapulohumeral Muscular Dystrophy COMPLETED NCT02836418
Placebo DRUG Phase PHASE2 Interstitial Lung Disease RECRUITING NCT05892614
Total products: 32