SymbolASMB
NameASSEMBLY BIOSCIENCES, INC.
SectorHEALTH CARE
RegionNorth America
IndustryBiotechnology: Pharmaceutical Preparations
AddressTWO TOWER PLACE,7TH FLOOR, SOUTH SAN FRANCISCO, California, 94080, United States
Telephone+1 833 509-4583
Fax
Email
Websitehttps://www.assemblybio.com
IncorporationUNDEFINED
Incorporated On
Employees
Fiscal Year
Public Since
ExchangesNASDAQ
Auditor
Audit StatusNOT PROVIDED
Reporting Status
CIK0001426800
Description

Assembly Biosciences Inc is a clinical-stage biotechnology company. It is advancing two innovative platform programs, a novel class of oral therapeutics for the treatment of hepatitis B virus (HBV) infection and novel class of oral synthetic live biotherapeutics, which are designed to restore health to a dysbiotic microbiome. The companys HBV-cure program is aimed at increasing the current low cure rate for patients with HBV and is pursuing multiple drug candidates that inhibit multiple steps of the HBV lifecycle. Assembly has discovered several novel core protein Allosteric Modulators, which are small molecules that directly target and allosterically modulate the HBV core protein. The majority of the revenue is generated from the HBV cure program.

Additional info from NASDAQ:
Assembly Biosciences Inc is a clinical-stage biotechnology company. It is advancing two innovative platform programs, a novel class of oral therapeutics for the treatment of hepatitis B virus (HBV) infection and novel class of oral synthetic live biotherapeutics, which are designed to restore health to a dysbiotic microbiome. The companys HBV-cure program is aimed at increasing the current low cure rate for patients with HBV and is pursuing multiple drug candidates that inhibit multiple steps of the HBV lifecycle. Assembly has discovered several novel core protein Allosteric Modulators, which are small molecules that directly target and allosterically modulate the HBV core protein. The majority of the revenue is generated from the HBV cure program.

2026-06-05 21:11

Gaggar Anuj 🟢 acquired 14.0K shares of ASSEMBLY BIOSCIENCES, INC. (ASMB) Transaction Date: Mar 29, 2026 | Filing ID: 259927

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2026-06-05 21:10

White Nicole S 🟢 acquired 14.0K shares of ASSEMBLY BIOSCIENCES, INC. (ASMB) Transaction Date: Mar 29, 2026 | Filing ID: 259924

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2026-06-05 21:00

McHutchison John G 🟢 acquired 8.0K shares (1 derivative) of ASSEMBLY BIOSCIENCES, INC. (ASMB) at $24.11 Transaction Date: Jun 04, 2026 | Filing ID: 259855

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2026-06-05 20:50

Mahony Susan 🟢 acquired 8.0K shares (1 derivative) of ASSEMBLY BIOSCIENCES, INC. (ASMB) at $24.11 Transaction Date: Jun 04, 2026 | Filing ID: 259822

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2026-06-05 20:45

Johnson-Pratt Lisa 🟢 acquired 8.0K shares (1 derivative) of ASSEMBLY BIOSCIENCES, INC. (ASMB) at $24.11 Transaction Date: Jun 04, 2026 | Filing ID: 259808

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2026-06-05 20:35

Consylman Gina 🟢 acquired 8.0K shares (1 derivative) of ASSEMBLY BIOSCIENCES, INC. (ASMB) at $24.11 Transaction Date: Jun 04, 2026 | Filing ID: 259742

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2026-06-05 20:30

ALTIG ANTHONY E 🟢 acquired 8.0K shares (1 derivative) of ASSEMBLY BIOSCIENCES, INC. (ASMB) at $24.11 Transaction Date: Jun 04, 2026 | Filing ID: 259697

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2026-06-05 20:25

Bjorkquist Jeanette M 🟢 acquired 3.5K shares of ASSEMBLY BIOSCIENCES, INC. (ASMB) Transaction Date: Mar 29, 2026 | Filing ID: 259661

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2026-06-05 20:10

Delaney William E IV 🟢 acquired 14.0K shares of ASSEMBLY BIOSCIENCES, INC. (ASMB) Transaction Date: Mar 29, 2026 | Filing ID: 259562

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2026-06-05 20:05

Okazaki Jason A 🟢 acquired 50.8K shares of ASSEMBLY BIOSCIENCES, INC. (ASMB) Transaction Date: Mar 29, 2026 | Filing ID: 259517

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Trial ID Title Phase Indication Status Start Date Completion Date Source
NCT07208422 Task-Specific Self-Rehabilitation Training (TASSRET) Trial Na Stroke Completed 2025-06-07 2026-02-21 ClinicalTrials.gov
NCT06740474 A Study to Assess the Safety, Tolerability and Pharmacokinetics of ABI-6250 in … Phase1 Hepatitis Delta Virus Completed 2025-01-31 2025-07-08 ClinicalTrials.gov
NCT06698575 A Study to Assess the Safety, Pharmacokinetics, and Tolerability of ABI-1179 in… Phase1 Recurrent Genital Herpes Simplex Type 2 Completed 2024-12-08 2026-01-19 ClinicalTrials.gov
NCT06384131 A Study to Assess the Safety, Pharmacokinetics, and Antiviral Activity of ABI-4… Phase1 Chronic Hepatitis B Completed 2024-06-04 2025-05-14 ClinicalTrials.gov
NCT06385327 A Study to Assess the Safety, Pharmacokinetics, and Antiviral Activity of ABI-5… Phase1 Recurrent Genital Herpes Simplex Type 2 Completed 2024-05-30 2026-02-03 ClinicalTrials.gov
NCT05569941 A First in Human Study to Assess Safety, Tolerability, Pharmacokinetics of ABI-… Phase1 Chronic Hepatitis B Completed 2022-11-11 2023-04-12 ClinicalTrials.gov
NCT05414981 A Study to Assess the Safety, Pharmacokinetics, and Antiviral Activity of ABI-H… Phase1 Chronic Hepatitis B Completed 2022-08-07 2023-04-24 ClinicalTrials.gov
NCT04781647 A Study Evaluating ABI-H0731-containing Regimens in Chinese Participants With C… Phase2 Chronic Hepatitis B Terminated 2021-02-18 2022-12-02 ClinicalTrials.gov
NCT04637139 A Study to Evaluate the Mass Balance Absorption and AME of VBR Phase1 Chronic Hepatitis B Completed 2020-12-01 2020-12-22 ClinicalTrials.gov
NCT04454567 A Study Evaluating Treatment Intensification With ABI-H0731 in Participants Wit… Phase2 Chronic Hepatitis B Terminated 2020-11-11 2021-04-08 ClinicalTrials.gov
NCT04398134 A Study of ABI-H2158-containing Regimens in Participants With Chronic Hepatitis… Phase2 Chronic Hepatitis B Terminated 2020-08-28 2021-12-28 ClinicalTrials.gov
NCT04271592 A Study to Assess Safety, Tolerability, and Pharmacokinetics of ABI-H3733 in He… Phase1 Chronic Hepatitis B Completed 2020-05-17 2021-01-14 ClinicalTrials.gov
NCT04142762 A Study to Assess CYP3A4 Modulator, Oral Contraceptive, and pH Modifier Drug In… Phase1 Chronic Hepatitis B Completed 2019-10-18 2020-01-29 ClinicalTrials.gov
NCT04083716 A Study to Assess the Relative Bioavailability and Food Effect of ABI-H2158 in … Phase1 Chronic Hepatitis B Completed 2019-09-06 2019-10-07 ClinicalTrials.gov
NCT03923478 ABI-M201 in Adult Subjects With Mildly-to-Moderately Active Ulcerative Colitis Phase1 Ulcerative Colitis Chronic Mild Terminated 2019-06-24 2021-01-20 ClinicalTrials.gov
NCT03780543 A Study of ABI-H0731 + Nucleos(t)Ide as Finite Treatment for Chronic Hepatitis … Phase2 Chronic Hepatitis B Terminated 2018-12-20 2021-04-26 ClinicalTrials.gov
NCT03714152 A Study of ABI-H2158 in Healthy Volunteers and Patients With Chronic Hepatitis B Phase1 Chronic Hepatitis B Completed 2018-11-13 2021-01-07 ClinicalTrials.gov
NCT03577171 A Study Evaluating ABI-H0731+ Entecavir vs Entecavir Alone for the Treatment of… Phase2 Chronic Hepatitis B Completed 2018-06-19 2019-06-21 ClinicalTrials.gov
NCT03576066 A Study Evaluating ABI-H0731 as Adjunctive Therapy in Participants With Chronic… Phase2 Chronic Hepatitis B Completed 2018-06-11 2019-07-05 ClinicalTrials.gov
NCT03109730 Phase 1b/2a Study of ABI-H0731 in Patients With Chronic Hepatitis B Phase1 Chronic Hepatitis B Completed 2017-06-15 2018-06-12 ClinicalTrials.gov
NCT02908191 A Study in Healthy Volunteers and Patients With Chronic Hepatitis B Phase1 Chronic Hepatitis B Completed 2016-11-01 2018-06-12 ClinicalTrials.gov
NCT02234973 Transformation of Indigenous Primary Healthcare Delivery Type 2 Diabetes Mellitus Completed 2014-09-01 2020-03-31 ClinicalTrials.gov
Total clinical trials: 22
Product Name Type Development Stage Therapeutic Area Study Status Trial ID
Manual-based Task-specific Training Other Approved Stroke COMPLETED NCT07208422
Video-based Task-specific Training Other Approved Stroke COMPLETED NCT07208422
Quality Improvement Other Preclinical Type 2 Diabetes Mellitus COMPLETED NCT02234973
Quality Improvement Other Preclinical Type 2 Diabetes Mellitus COMPLETED NCT02234973
Pegasys Other Phase PHASE1 Chronic Hepatitis B COMPLETED NCT03109730
Tenofovir Disoproxil Fumarate Other Phase PHASE1 Chronic Hepatitis B COMPLETED NCT03109730
Entecavir Other Phase PHASE1 Chronic Hepatitis B COMPLETED NCT03109730
Placebo for ABI-H0731 Other Phase PHASE1 Chronic Hepatitis B COMPLETED NCT03109730
ABI-H0731 Other Phase PHASE1 Chronic Hepatitis B COMPLETED NCT03109730
Nucleos(t)ide Other Phase PHASE1 Chronic Hepatitis B COMPLETED NCT02908191
Pegasys Other Phase PHASE1 Chronic Hepatitis B COMPLETED NCT02908191
Tenofovir disoproxil fumarate Other Phase PHASE1 Chronic Hepatitis B COMPLETED NCT02908191
Entecavir Other Phase PHASE1 Chronic Hepatitis B COMPLETED NCT02908191
Placebo for ABI-H0731 Other Phase PHASE1 Chronic Hepatitis B COMPLETED NCT02908191
ABI-H0731 Other Phase PHASE1 Chronic Hepatitis B COMPLETED NCT02908191
ABI-H2158 Test Formulation Other Phase PHASE1 Chronic Hepatitis B COMPLETED NCT04083716
ABI-H2158 Reference Formulation Other Phase PHASE1 Chronic Hepatitis B COMPLETED NCT04083716
Placebo matching oral contraceptive Other Phase PHASE1 Chronic Hepatitis B COMPLETED NCT04142762
Esomeprazole Other Phase PHASE1 Chronic Hepatitis B COMPLETED NCT04142762
Ethinyl Estradiol / Levonorgestrel Other Phase PHASE1 Chronic Hepatitis B COMPLETED NCT04142762
Midazolam Other Phase PHASE1 Chronic Hepatitis B COMPLETED NCT04142762
Rifampin Other Phase PHASE1 Chronic Hepatitis B COMPLETED NCT04142762
Itraconazole Other Phase PHASE1 Chronic Hepatitis B COMPLETED NCT04142762
ABI-H2158 Other Phase PHASE1 Chronic Hepatitis B COMPLETED NCT04142762
Vebicorvir (VBR) Other Phase PHASE1 Chronic Hepatitis B COMPLETED NCT04637139
Placebo to ABI-H3733 Solid Oral Dosage Form Other Phase PHASE1 Chronic Hepatitis B COMPLETED NCT04271592
Placebo to ABI-H3733 Liquid Oral Dosage Form Other Phase PHASE1 Chronic Hepatitis B COMPLETED NCT04271592
ABI-H3733 Solid Oral Dosage Form Other Phase PHASE1 Chronic Hepatitis B COMPLETED NCT04271592
ABI-H3733 Liquid Oral Dosage Form Other Phase PHASE1 Chronic Hepatitis B COMPLETED NCT04271592
Placebo for ABI-H2158 Other Phase PHASE1 Chronic Hepatitis B COMPLETED NCT03714152
ABI-H2158 Other Phase PHASE1 Chronic Hepatitis B COMPLETED NCT03714152
Placebo Oral Tablet Other Phase PHASE2 Chronic Hepatitis B COMPLETED NCT03577171
SOC ETV Other Phase PHASE2 Chronic Hepatitis B COMPLETED NCT03577171
ABI-H0731 Other Phase PHASE2 Chronic Hepatitis B COMPLETED NCT03577171
Placebo Oral Tablet Other Phase PHASE2 Chronic Hepatitis B COMPLETED NCT03576066
SOC NUC Other Phase PHASE2 Chronic Hepatitis B COMPLETED NCT03576066
ABI-H0731 Other Phase PHASE2 Chronic Hepatitis B COMPLETED NCT03576066
Placebo Other Phase PHASE1 Ulcerative Colitis Chronic Mild TERMINATED NCT03923478
ABI-M201 Other Phase PHASE1 Ulcerative Colitis Chronic Mild TERMINATED NCT03923478
Entecavir (ETV) Other Phase PHASE2 Chronic Hepatitis B TERMINATED NCT04398134
Placebo Other Phase PHASE2 Chronic Hepatitis B TERMINATED NCT04398134
ABI-H2158 Other Phase PHASE2 Chronic Hepatitis B TERMINATED NCT04398134
NrtI Other Phase PHASE2 Chronic Hepatitis B TERMINATED NCT04454567
Placebo Other Phase PHASE2 Chronic Hepatitis B TERMINATED NCT04454567
ABI-H0731 Other Phase PHASE2 Chronic Hepatitis B TERMINATED NCT04454567
standard of care (SOC) Nucleoside reverse transcriptase inhibitor (NrtI) Other Phase PHASE2 Chronic Hepatitis B TERMINATED NCT03780543
Placebo Other Phase PHASE1 Chronic Hepatitis B COMPLETED NCT05414981
ABI-H3733 Other Phase PHASE1 Chronic Hepatitis B COMPLETED NCT05414981
ABI-4334 Placebo Other Phase PHASE1 Chronic Hepatitis B COMPLETED NCT05569941
ABI-4334 Tablet Other Phase PHASE1 Chronic Hepatitis B COMPLETED NCT05569941
Peg-IFNα Other Phase PHASE2 Chronic Hepatitis B TERMINATED NCT04781647
ETV Other Phase PHASE2 Chronic Hepatitis B TERMINATED NCT04781647
ABI-H0731 Other Phase PHASE2 Chronic Hepatitis B TERMINATED NCT04781647
Placebo Other Phase PHASE1 Chronic Hepatitis B COMPLETED NCT06384131
ABI-4334 Other Phase PHASE1 Chronic Hepatitis B COMPLETED NCT06384131
Placebo Other Phase PHASE1 Hepatitis Delta Virus COMPLETED NCT06740474
ABI-6250 Other Phase PHASE1 Hepatitis Delta Virus COMPLETED NCT06740474
ABI-1179 Placebo Other Phase PHASE1 Recurrent Genital Herpes Simplex Type 2 COMPLETED NCT06698575
ABI-1179 Other Phase PHASE1 Recurrent Genital Herpes Simplex Type 2 COMPLETED NCT06698575
ABI-5366 Placebo Other Phase PHASE1 Recurrent Genital Herpes Simplex Type 2 COMPLETED NCT06385327
ABI-5366 Other Phase PHASE1 Recurrent Genital Herpes Simplex Type 2 COMPLETED NCT06385327
Quality Improvement BEHAVIORAL Preclinical Type 2 Diabetes Mellitus COMPLETED NCT02234973
Total products: 62