SymbolACRS
NameACLARIS THERAPEUTICS, INC.
SectorHEALTH CARE
RegionNorth America
IndustryBiotechnology: Pharmaceutical Preparations
Address701 LEE ROAD,SUITE 103, WAYNE, Pennsylvania, 19087, United States
Telephone+1 484 - 324-7933
Fax
Email
Websitehttps://www.aclaristx.com
IncorporationUNDEFINED
Incorporated On
Employees
Fiscal Year
Public Since
ExchangesNASDAQ
Auditor
Audit StatusNOT PROVIDED
Reporting Status
CIK
Description

Aclaris Therapeutics Inc is a clinical-stage biopharmaceutical company that operates in the United States. It focuses on developing novel drug candidates for immuno-inflammatory diseases. The company operates in two segments: therapeutics and contract research. The majority of its revenue comes from the contract research segment, which provides laboratory services. Its drug candidates under development are Zunsemetinib, which is an Oral MK2 Inhibitor; ATI-2138 is an ITJ Inhibitor; and ATI-1777.

Additional info from NASDAQ:
Aclaris Therapeutics Inc is a clinical-stage biopharmaceutical company that operates in the United States. It focuses on developing novel drug candidates for immuno-inflammatory diseases. The company operates in two segments: therapeutics and contract research. The majority of its revenue comes from the contract research segment, which provides laboratory services. Its drug candidates under development are Zunsemetinib, which is an Oral MK2 Inhibitor; ATI-2138 is an ITJ Inhibitor; and ATI-1777.

2026-04-08 12:30

Aclaris Therapeutics to Participate in the H.C. Wainwright 4th Annual Inflammatory Skin Disease Virtual Conference

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2026-04-07 19:00

New Form SCHEDULE 13G - Aclaris Therapeutics, Inc. <b>Filed:</b> 2026-04-07 <b>AccNo:</b> 0001346824-26-000099 <b>Size:</b> 18 KB

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2026-03-27 14:10

Results Presented at 2026 American Academy of Dermatology (AAD) Annual Meeting Provide Additional Support for the Therapeutic Potential of ATI-2138

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2026-03-26 16:06

New Form SCHEDULE 13G/A - Aclaris Therapeutics, Inc. <b>Filed:</b> 2026-03-26 <b>AccNo:</b> 0000102909-26-000505 <b>Size:</b> 7 KB

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2026-03-20 15:00

Aclaris Therapeutics Announces Poster on Results from Phase 2a Trial of ATI-2138 at the 2026 American Academy of Dermatology (AAD) Annual Meeting

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2026-03-18 10:55

Aclaris Therapeutics Completes Enrollment in Phase 2 Trial of Bosakitug (ATI-045) in Atopic Dermatitis

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2026-03-17 17:17

New Form SCHEDULE 13G - Aclaris Therapeutics, Inc. <b>Filed:</b> 2026-03-17 <b>AccNo:</b> 0001172661-26-001355 <b>Size:</b> 11 KB

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2026-02-26 12:15

(30% Negative) Aclaris Therapeutics Inc (ACRS) Reports Q1 2026 Financial Results

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2026-02-26 11:58

Aclaris Therapeutics Reports Fourth Quarter and Full Year 2025 Financial Results and Provides Corporate Update

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2026-02-24 12:00

Aclaris Therapeutics Initiates Phase 1b Proof-of-Concept Trial in Patients with Asthma with its Novel Bispecific Anti-TSLP/IL-4Rα Antibody ATI-052

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Trial ID Title Phase Indication Status Start Date Completion Date Source
NCT07011706 ATI-045 Versus Placebo in Patients With Moderate-to-Severe Atopic Dermatitis Phase2 Atopic Dermatitis Active_Not_Recruiting 2025-05-30 2026-10-01 ClinicalTrials.gov
NCT06648434 MK2 Inhibitor in Combination With mFOLFIRINOX for Untreated Metastatic Pancreat… Phase1 Metastatic Pancreatic Ductal Adenocarcinoma Recruiting 2025-05-15 2030-05-31 ClinicalTrials.gov
NCT06374459 Zunsemetinib in Combination With Capecitabine in Patients With Hormone Receptor… Phase1 Hormone Receptor Positive HER-2 Negative Metastatic Breast Cancer Recruiting 2025-01-30 2032-05-31 ClinicalTrials.gov
NCT06585202 Study of ATI-2138 in Adult Participants With Moderate to Severe Atopic Dermatit… Phase2 Atopic Dermatitis Completed 2024-08-19 2025-03-31 ClinicalTrials.gov
NCT05791474 ATI-2231 in Advanced Solid Tumor Malignancies Phase1 Advanced Solid Tumor Withdrawn 2023-11-15 2025-06-30 ClinicalTrials.gov
NCT05511519 Study of ATI-450 vs Placebo in Patients With Moderate to Severe Psoriatic Arthr… Phase2 Psoriatic Arthritis Terminated 2022-07-12 2024-01-03 ClinicalTrials.gov
NCT05432596 Study of ATI-1777 in Patients 12 to 65 Years Old With Mild to Severe Atopic Der… Phase2 Atopic Dermatitis Completed 2022-05-11 2023-11-14 ClinicalTrials.gov
NCT05279417 ATI-450 Plus Methotrexate (MTX) Versus Placebo Plus MTX in Participants With Mo… Phase2 Rheumatoid Arthritis Completed 2022-02-01 2023-10-11 ClinicalTrials.gov
NCT05216224 ATI-450 vs Placebo in Participants With Moderate to Severe Hidradenitis Suppura… Phase2 Hidradenitis Suppurativa Completed 2021-12-29 2023-01-24 ClinicalTrials.gov
NCT05114889 Safety and Tolerability of BSI-045B in Healthy Adult Subjects and Patients With… Phase1 Atopic Dermatitis Completed 2021-10-25 2023-02-15 ClinicalTrials.gov
NCT04524858 Study of ATI-450 in Patients With Cryopyrin-Associated Periodic Syndrome (CAPS) Phase2 Cryopyrin-Associated Periodic Syndrome Terminated 2020-10-23 2021-02-25 ClinicalTrials.gov
NCT04598269 Study of ATI-1777 in Adult Patients With Moderate or Severe Atopic Dermatitis Phase2 Atopic Dermatitis Completed 2020-09-30 2021-04-22 ClinicalTrials.gov
NCT04247815 Study of ATI-450 Plus Methotrexate (MTX) vs MTX Alone in Patients With Moderate… Phase2 Rheumatoid Arthritis Completed 2020-03-16 2021-02-04 ClinicalTrials.gov
NCT03812510 Safety Study of A-101 Topical Solution for the Treatment of Common Warts Phase3 Common Wart Completed 2019-02-07 2019-12-20 ClinicalTrials.gov
NCT03759340 ATI-502 Topical Solution for the Treatment of Alopecia Areata (AA), Alopecia Un… Phase2 Alopecia Areata Terminated 2019-01-15 2019-09-11 ClinicalTrials.gov
NCT03687372 Study of A-101 Topical Solution for the Treatment of Common Warts Phase3 Common Wart Completed 2018-09-17 2019-09-06 ClinicalTrials.gov
NCT03691831 A Study of A-101 Topical Solution for the Treatment of Common Warts Phase3 Common Wart Completed 2018-09-13 2019-07-09 ClinicalTrials.gov
NCT03585296 A Study of ATI-502 Topical Solution for the Treatment of Atopic Dermatitis Phase2 Atopic Dermatitis Completed 2018-07-10 2019-04-25 ClinicalTrials.gov
NCT03594227 ATI-501 Oral Suspension Compared to Placebo in Subjects With Alopecia Areata, A… Phase2 Alopecia Completed 2018-06-11 2019-06-18 ClinicalTrials.gov
NCT03551821 Open Label Study of ATI-50002 Topical Solution Administered to Adult Subjects W… Phase2 Alopecia Areata Completed 2018-04-11 2018-11-06 ClinicalTrials.gov
NCT03495817 A Study in Male and Female Subjects With Androgenetic Alopecia Treated With ATI… Phase2 Androgenetic Alopecia Completed 2018-03-22 2019-10-30 ClinicalTrials.gov
NCT03487588 An A Study Assessing Subject Satisfaction With A-101 Topical Solution for Sebor… Phase4 Seborrheic Keratosis Completed 2018-03-21 2018-11-14 ClinicalTrials.gov
NCT03468855 A Study of ATI-50002 Topical Solution for the Treatment of Vitiligo Phase2 Vitiligo Completed 2018-03-19 2019-10-16 ClinicalTrials.gov
NCT03315689 Safety and Pharmacokinetic Study of ATI-50002 in Subjects With Alopecia Univers… Phase2 Alopecia Universalis (AU) Completed 2017-12-14 2019-06-20 ClinicalTrials.gov
NCT03380390 Safety and Tolerability of Oxymetazoline and Energy-Based Therapy in Participan… Phase4 Rosacea Completed 2017-12-04 2018-06-15 ClinicalTrials.gov
NCT03354637 A Study of ATI-50002 Topical Solution for the Treatment of Alopecia Areata Phase2 Alopecia Areata Terminated 2017-11-29 2019-09-10 ClinicalTrials.gov
NCT03210337 A Phase2 of A-101 Topical Solution in Subjects With Common Warts Phase2 Common Wart Completed 2017-08-01 2018-03-16 ClinicalTrials.gov
NCT03278028 A Study of A-101 Topical Solution Administered Twice a Week in Subjects With Co… Phase2 Common Wart Completed 2017-07-13 2018-03-01 ClinicalTrials.gov
NCT03224598 A Study of A-101 Topical Solution in Subjects With Dermatosis Papulosa Nigra Phase2 Dermatosis Papulosa Nigra Completed 2017-06-26 2019-01-08 ClinicalTrials.gov
NCT03148691 A Randomized, Vehicle-Controlled Study of 2 Concentrations of A-101 for the Tre… Phase2 Seborrheic Keratosis Completed 2017-05-17 2018-04-03 ClinicalTrials.gov
NCT02667236 A Study of A-101 Solution 40% in Subjects With Seborrheic Keratosis. Phase3 Seborrheic Keratosis Completed 2016-01-01 2016-10-01 ClinicalTrials.gov
NCT02667275 A Randomized, Double-Blind, Vehicle-Controlled Study in Subjects With Seborrhei… Phase3 Seborrheic Keratosis Completed 2016-01-01 2016-10-01 ClinicalTrials.gov
NCT02667288 An Open-Label Safety Study of A-101 Solution Phase3 Seborrheic Keratosis Completed 2016-01-01 2016-10-01 ClinicalTrials.gov
NCT02669862 A Study of A-101 Solution in Subjects With Common Warts. Phase2 Common Warts Completed 2015-12-21 2016-09-16 ClinicalTrials.gov
NCT02260180 Study of A-101 for the Treatment of Seborrheic Keratosis Phase2 Seborrheic Keratosis Completed 2014-10-01 2015-03-01 ClinicalTrials.gov
NCT02160626 Dose-Response Profile of A-101 in Subjects With Seborrheic Keratosis Phase2 Seborrheic Keratosis Completed 2014-06-01 2014-12-01 ClinicalTrials.gov
NCT01986920 Study of Safety, Tolerability and Effectiveness of A-101 in Subjects With Sebor… Phase1 Seborrheic Keratosis (SK) Completed 2013-10-22 2014-02-25 ClinicalTrials.gov
Total clinical trials: 37
Product Name Type Development Stage Therapeutic Area Study Status Trial ID
ATI-045 DRUG Phase PHASE2 Atopic Dermatitis ACTIVE_NOT_RECRUITING NCT07011706
mFOLFIRINOX DRUG Phase PHASE1 Metastatic Pancreatic Ductal Adenocarcinoma RECRUITING NCT06648434
Zunsemetinib DRUG Phase PHASE1 Metastatic Pancreatic Ductal Adenocarcinoma RECRUITING NCT06648434
ATI-2138 DRUG Phase PHASE2 Atopic Dermatitis COMPLETED NCT06585202
Denosumab DRUG Phase PHASE1 Hormone Receptor Positive HER-2 Negative Metastatic Breast Cancer RECRUITING NCT06374459
Zoledronic acid DRUG Phase PHASE1 Hormone Receptor Positive HER-2 Negative Metastatic Breast Cancer RECRUITING NCT06374459
Capecitabine DRUG Phase PHASE1 Hormone Receptor Positive HER-2 Negative Metastatic Breast Cancer RECRUITING NCT06374459
Zumsemetinib DRUG Phase PHASE1 Hormone Receptor Positive HER-2 Negative Metastatic Breast Cancer RECRUITING NCT06374459
ATI-2231 DRUG Phase PHASE1 Advanced Solid Tumor WITHDRAWN NCT05791474
Placebo Oral Tablet DRUG Phase PHASE2 Psoriatic Arthritis TERMINATED NCT05511519
ATI-1777 0.5% w/w DRUG Phase PHASE2 Atopic Dermatitis COMPLETED NCT05432596
ATI-1777 1.0% w/w DRUG Phase PHASE2 Atopic Dermatitis COMPLETED NCT05432596
ATI-1777 2.0% w/w DRUG Phase PHASE2 Atopic Dermatitis COMPLETED NCT05432596
ATI-450 20 mg oral tablet BID DRUG Phase PHASE2 Rheumatoid Arthritis COMPLETED NCT05279417
ATI-450 50 mg oral tablet BID DRUG Phase PHASE2 Rheumatoid Arthritis COMPLETED NCT05279417
BSI-045B BIOLOGICAL Phase PHASE1 Atopic Dermatitis COMPLETED NCT05114889
ATI-1777 DRUG Phase PHASE2 Atopic Dermatitis COMPLETED NCT04598269
Methotrexate DRUG Phase PHASE2 Rheumatoid Arthritis COMPLETED NCT05279417
Placebo oral tablet DRUG Phase PHASE2 Rheumatoid Arthritis COMPLETED NCT05279417
ATI-450 DRUG Phase PHASE2 Psoriatic Arthritis TERMINATED NCT05511519
ATI 502 0.46% Topical Solution DRUG Phase PHASE2 Alopecia Areata TERMINATED NCT03759340
Active DRUG Phase PHASE3 Common Wart COMPLETED NCT03691831
vehicle OTHER Phase PHASE3 Common Wart COMPLETED NCT03687372
ATI-501 800mg BID (High dose) DRUG Phase PHASE2 Alopecia COMPLETED NCT03594227
ATI-501 600mg BID (Mid dose) DRUG Phase PHASE2 Alopecia COMPLETED NCT03594227
ATI-501 400mg BID (Low dose) DRUG Phase PHASE2 Alopecia COMPLETED NCT03594227
ATI-502 DRUG Phase PHASE2 Atopic Dermatitis COMPLETED NCT03585296
ATI-50002 topical solution DRUG Phase PHASE2 Vitiligo COMPLETED NCT03468855
Energy-Based Therapy DEVICE Phase PHASE4 Rosacea COMPLETED NCT03380390
Oxymetazoline HCL 1.0% Cream DRUG Phase PHASE4 Rosacea COMPLETED NCT03380390
Placebo DRUG Phase PHASE2 Atopic Dermatitis ACTIVE_NOT_RECRUITING NCT07011706
ATI-50002 low dose DRUG Phase PHASE2 Alopecia Areata TERMINATED NCT03354637
ATI-50002 high dose DRUG Phase PHASE2 Alopecia Areata TERMINATED NCT03354637
ATI-50002 DRUG Phase PHASE2 Alopecia Areata COMPLETED NCT03551821
Vehicle DRUG Phase PHASE2 Atopic Dermatitis COMPLETED NCT05432596
A-101 Topical Solution 40% DRUG Phase PHASE2 Dermatosis Papulosa Nigra COMPLETED NCT03224598
A-101 Vehicle Solution DRUG Phase PHASE2 Common Wart COMPLETED NCT03278028
A-101 Topical Solution DRUG Phase PHASE4 Seborrheic Keratosis COMPLETED NCT03487588
A-101 Solution 45 DRUG Phase PHASE2 Common Warts COMPLETED NCT02669862
A-101 Solution 40 DRUG Phase PHASE2 Common Warts COMPLETED NCT02669862
Vehicle Solution DRUG Phase PHASE2 Common Warts COMPLETED NCT02669862
A-101 Solution DRUG Phase PHASE3 Seborrheic Keratosis COMPLETED NCT02667288
A-101 DRUG Phase PHASE3 Common Wart COMPLETED NCT03812510
A-101 (32.5) Topical Solution DRUG Phase PHASE2 Seborrheic Keratosis COMPLETED NCT02160626
A-101 (40) Topical Solution DRUG Phase PHASE2 Seborrheic Keratosis COMPLETED NCT02160626
A-101 Vehicle DRUG Phase PHASE2 Seborrheic Keratosis COMPLETED NCT02160626
A-101 40% DRUG Phase PHASE1 Seborrheic Keratosis (SK) COMPLETED NCT01986920
A-101 32.5% DRUG Phase PHASE1 Seborrheic Keratosis (SK) COMPLETED NCT01986920
A-101 25% DRUG Phase PHASE1 Seborrheic Keratosis (SK) COMPLETED NCT01986920
Total products: 49