SymbolABOS
NameACUMEN PHARMACEUTICALS, INC.
SectorHEALTH CARE
RegionNorth America
IndustryBiotechnology: Biological Products (No Diagnostic Substances)
Address427 PARK STREET, CHARLOTTESVILLE, Virginia, 22902, United States
Telephone+1 434 297-1000
Fax
Email
Websitehttps://www.acumenpharm.com
IncorporationUNDEFINED
Incorporated On
Employees
Fiscal Year
Public Since
ExchangesNASDAQ
Auditor
Audit StatusNOT PROVIDED
Reporting Status
CIK0001576885
Description

Acumen Pharmaceuticals Inc is a clinical-stage biopharmaceutical company developing a novel disease-modifying approach to target what we believe to be a key underlying cause of Alzheimers disease. The companys lead drug candidate, ACU193, is a subclass monoclonal antibody which selectively targets amyloid-beta oligomers.

Additional info from NASDAQ:
Acumen Pharmaceuticals Inc is a clinical-stage biopharmaceutical company developing a novel disease-modifying approach to target what we believe to be a key underlying cause of Alzheimers disease. The companys lead drug candidate, ACU193, is a subclass monoclonal antibody which selectively targets amyloid-beta oligomers.

2026-07-15 11:30

Acumen Pharmaceuticals Highlights Enhanced Brain Delivery™ (EBD™) Program Data and Early Alzheimer’s Disease Insights at the Alzheimer’s Association International Conference (AAIC®) 2026

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2026-06-17 21:10

Director Porter Derrell 🟡 adjusted position in 32.3K shares (2 derivative) of Acumen Pharmaceuticals, Inc. (ABOS) at $2.35 Transaction Date: Jun 15, 2026 | Filing ID: 043987

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2026-06-17 20:02

📋 DERRELL PORTER (Director) plans to sell 13K shares of ACUMEN PHARMACEUTICALS, INC. (at $2.33 each, total $30K) Filed: Jun 17, 2026 | ID: 006245

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2026-06-16 21:03

📋 DERRELL PORTER (Director) plans to sell 13K shares of ACUMEN PHARMACEUTICALS, INC. (at $2.33 each, total $30K) Filed: Jun 16, 2026 | ID: 006235

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2026-06-16 11:34

(91% Neutral) ACUMEN PHARMACEUTICALS, INC. (ABOS) Provides Update on submission for a stable

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2026-06-16 11:30

Acumen Pharmaceuticals Announces Nomination of Two Enhanced Brain Delivery™ (EBD™) Development Candidates for the Treatment of Alzheimer’s Disease

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2026-06-15 22:31

📋 DERRELL PORTER (Director) plans to sell 6K shares of ACUMEN PHARMACEUTICALS, INC. (at $2.35 each, total $15K) Filed: Jun 15, 2026 | ID: 006161

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2026-06-10 20:51

Director Fountain Nathan B 🔴 sold 6.4K shares of Acumen Pharmaceuticals, Inc. (ABOS) at $2.23 Transaction Date: Jun 09, 2026 | Filing ID: 042280

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2026-06-09 20:15

📋 NATHAN FOUNTAIN (Director) plans to sell 6K shares of ACUMEN PHARMACEUTICALS, INC. (at $2.23 each, total $14K) Filed: Jun 09, 2026 | ID: 005810

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2026-06-05 21:12

RA CAPITAL MANAGEMENT, L.P. 🟢 acquired 88.8K shares (1 derivative) of Acumen Pharmaceuticals, Inc. (ABOS) at $2.29 Transaction Date: Jun 03, 2026 | Filing ID: 000604

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Trial ID Title Phase Indication Status Start Date Completion Date Source
NCT07430202 A DNAJB1-PRKACA Fusion Kinase Peptide Vaccine Combined With Glutamine Antagonis… Phase1 Liver Cancer (Fibrolamellar Hepatocellular Cancer (FLC)) Not_Yet_Recruiting 2026-08-01 2030-08-01 ClinicalTrials.gov
NCT07430202 A DNAJB1-PRKACA Fusion Kinase Peptide Vaccine Combined With Glutamine Antagonis… Phase1 Liver Cancer (Fibrolamellar Hepatocellular Cancer (FLC)) Not_Yet_Recruiting 2026-08-01 2030-08-01 ClinicalTrials.gov
NCT06511570 A Study Comparing the Safety, Tolerability, and Pharmacokinetics of Sabirnetug … Phase1 Alzheimer Disease Completed 2024-06-25 2024-09-17 ClinicalTrials.gov
NCT06511570 A Study Comparing the Safety, Tolerability, and Pharmacokinetics of Sabirnetug … Phase1 Alzheimer Disease Completed 2024-06-25 2024-09-17 ClinicalTrials.gov
NCT06335173 A Study to Evaluate Efficacy and Safety of Intravenous Sabirnetug in Participan… Phase2 Alzheimer Disease Active_Not_Recruiting 2024-02-29 2026-10-01 ClinicalTrials.gov
NCT06335173 A Study to Evaluate Efficacy and Safety of Intravenous Sabirnetug in Participan… Phase2 Alzheimer Disease Active_Not_Recruiting 2024-02-29 2026-10-01 ClinicalTrials.gov
NCT06027086 DRP-104 (Glutamine Antagonist) in Combination With Durvalumab in Patients With … Phase1 Fibrolamellar Hepatocellular Carcinoma Recruiting 2024-02-12 2033-09-01 ClinicalTrials.gov
NCT06027086 DRP-104 (Glutamine Antagonist) in Combination With Durvalumab in Patients With … Phase1 Fibrolamellar Hepatocellular Carcinoma Recruiting 2024-02-12 2033-09-01 ClinicalTrials.gov
NCT04931459 A Study to Evaluate the Safety, Tolerability, and Blood Levels of ACU193 in Par… Phase1 Alzheimer Disease Completed 2021-06-21 2023-06-12 ClinicalTrials.gov
NCT04931459 A Study to Evaluate the Safety, Tolerability, and Blood Levels of ACU193 in Par… Phase1 Alzheimer Disease Completed 2021-06-21 2023-06-12 ClinicalTrials.gov
NCT04471415 Study to Investigate DRP-104 in Adults With Advanced Solid Tumors Phase1 Advanced Solid Tumor Terminated 2020-08-31 2023-03-28 ClinicalTrials.gov
NCT04471415 Study to Investigate DRP-104 in Adults With Advanced Solid Tumors Phase1 Advanced Solid Tumor Terminated 2020-08-31 2023-03-28 ClinicalTrials.gov
Total clinical trials: 12
Product Name Type Development Stage Therapeutic Area Study Status Trial ID
Ipilimumab Other Phase PHASE1 Liver Cancer (Fibrolamellar Hepatocellular Cancer (FLC)) NOT_YET_RECRUITING NCT07430202
Nivolumab Other Phase PHASE1 Liver Cancer (Fibrolamellar Hepatocellular Cancer (FLC)) NOT_YET_RECRUITING NCT07430202
DRP-104 Other Phase PHASE1 Liver Cancer (Fibrolamellar Hepatocellular Cancer (FLC)) NOT_YET_RECRUITING NCT07430202
DNAJB1-PRKACA Peptide Vaccine Other Phase PHASE1 Liver Cancer (Fibrolamellar Hepatocellular Cancer (FLC)) NOT_YET_RECRUITING NCT07430202
Ipilimumab Other Phase PHASE1 Liver Cancer (Fibrolamellar Hepatocellular Cancer (FLC)) NOT_YET_RECRUITING NCT07430202
Nivolumab Other Phase PHASE1 Liver Cancer (Fibrolamellar Hepatocellular Cancer (FLC)) NOT_YET_RECRUITING NCT07430202
DRP-104 Other Phase PHASE1 Liver Cancer (Fibrolamellar Hepatocellular Cancer (FLC)) NOT_YET_RECRUITING NCT07430202
DNAJB1-PRKACA Peptide Vaccine Other Phase PHASE1 Liver Cancer (Fibrolamellar Hepatocellular Cancer (FLC)) NOT_YET_RECRUITING NCT07430202
atezolizumab Other Phase PHASE1 Advanced Solid Tumor TERMINATED NCT04471415
DRP-104 Other Phase PHASE1 Advanced Solid Tumor TERMINATED NCT04471415
DRP-104 Other Phase PHASE1 Fibrolamellar Hepatocellular Carcinoma RECRUITING NCT06027086
Durvalumab Other Phase PHASE1 Fibrolamellar Hepatocellular Carcinoma RECRUITING NCT06027086
Ipilimumab Other Phase PHASE1 Liver Cancer (Fibrolamellar Hepatocellular Cancer (FLC)) NOT_YET_RECRUITING NCT07430202
Nivolumab Other Phase PHASE1 Liver Cancer (Fibrolamellar Hepatocellular Cancer (FLC)) NOT_YET_RECRUITING NCT07430202
DRP-104 Other Phase PHASE1 Liver Cancer (Fibrolamellar Hepatocellular Cancer (FLC)) NOT_YET_RECRUITING NCT07430202
DNAJB1-PRKACA Peptide Vaccine Other Phase PHASE1 Liver Cancer (Fibrolamellar Hepatocellular Cancer (FLC)) NOT_YET_RECRUITING NCT07430202
Ipilimumab Other Phase PHASE1 Liver Cancer (Fibrolamellar Hepatocellular Cancer (FLC)) NOT_YET_RECRUITING NCT07430202
Nivolumab Other Phase PHASE1 Liver Cancer (Fibrolamellar Hepatocellular Cancer (FLC)) NOT_YET_RECRUITING NCT07430202
DRP-104 Other Phase PHASE1 Liver Cancer (Fibrolamellar Hepatocellular Cancer (FLC)) NOT_YET_RECRUITING NCT07430202
DNAJB1-PRKACA Peptide Vaccine Other Phase PHASE1 Liver Cancer (Fibrolamellar Hepatocellular Cancer (FLC)) NOT_YET_RECRUITING NCT07430202
Ipilimumab Other Phase PHASE1 Liver Cancer (Fibrolamellar Hepatocellular Cancer (FLC)) NOT_YET_RECRUITING NCT07430202
Nivolumab Other Phase PHASE1 Liver Cancer (Fibrolamellar Hepatocellular Cancer (FLC)) NOT_YET_RECRUITING NCT07430202
DRP-104 Other Phase PHASE1 Liver Cancer (Fibrolamellar Hepatocellular Cancer (FLC)) NOT_YET_RECRUITING NCT07430202
DNAJB1-PRKACA Peptide Vaccine Other Phase PHASE1 Liver Cancer (Fibrolamellar Hepatocellular Cancer (FLC)) NOT_YET_RECRUITING NCT07430202
Placebo Other Phase PHASE1 Alzheimer Disease COMPLETED NCT04931459
ACU193 Other Phase PHASE1 Alzheimer Disease COMPLETED NCT04931459
Sabirnetug + rHuPH20 Other Phase PHASE1 Alzheimer Disease COMPLETED NCT06511570
sabirnetug (ACU193) Other Phase PHASE1 Alzheimer Disease COMPLETED NCT06511570
Placebo Other Phase PHASE2 Alzheimer Disease ACTIVE_NOT_RECRUITING NCT06335173
sabirnetug Other Phase PHASE2 Alzheimer Disease ACTIVE_NOT_RECRUITING NCT06335173
Diclofenac DRUG Phase PHASE3 Osteo Arthritis of the Knee COMPLETED NCT01456611
Lubiprostone DRUG Phase PHASE3 Chronic Idiopathic Constipation COMPLETED NCT01372423
atezolizumab BIOLOGICAL Phase PHASE1 Advanced Solid Tumor TERMINATED NCT04471415
Placebo oral capsule DRUG Phase PHASE2 Cystic Fibrosis COMPLETED NCT03265288
LAU-7b DRUG Phase PHASE2 Cystic Fibrosis COMPLETED NCT03265288
Placebo for 3 cycles OTHER Phase PHASE2 Long COVID COMPLETED NCT05999435
LAU-7b for 1 cycle, then placebo DRUG Phase PHASE2 Long COVID COMPLETED NCT05999435
LAU-7b for 3 cycles DRUG Phase PHASE2 Long COVID COMPLETED NCT05999435
Durvalumab DRUG Phase PHASE1 Fibrolamellar Hepatocellular Carcinoma RECRUITING NCT06027086
Ipilimumab DRUG Phase PHASE1 Liver Cancer (Fibrolamellar Hepatocellular Cancer (FLC)) NOT_YET_RECRUITING NCT07430202
Nivolumab DRUG Phase PHASE1 Liver Cancer (Fibrolamellar Hepatocellular Cancer (FLC)) NOT_YET_RECRUITING NCT07430202
DRP-104 DRUG Phase PHASE1 Advanced Solid Tumor TERMINATED NCT04471415
DNAJB1-PRKACA Peptide Vaccine DRUG Phase PHASE1 Liver Cancer (Fibrolamellar Hepatocellular Cancer (FLC)) NOT_YET_RECRUITING NCT07430202
Placebo DRUG Phase PHASE3 Osteo Arthritis of the Knee COMPLETED NCT01456611
Total products: 44